Комбинация Глюкозамина и Хондроитина рекомендуется взрослым и пожилым лицам в комплексном лечении заболеваний опорно-двигательного аппарата и других состояний, сопровождающихся дегенеративно-дистрофическими изменениями тканей суставного хряща и соединительной ткани: остеоартроз суставов I-III степени, в т.ч. крупных суставов (гонартроз), остеоартрит; ...
Гиперчувствительность к глюкозамину, хондроитину или любому другому компоненту препарата; выраженные нарушения функции почек (для приема внутрь); беременность и грудное вскармливание; дети младше 12 лет. Препараты Глюкозамина и Хондроитина применяют с осторожностью: кровотечения или склонность к кровотечениям.
Артра - стимулятор регенерации хрящевой ткани. ; Глюкозамин и хондроитин сульфат натрия принимают участие в биосинтезе соединительной ткани, способствуя предотвращению процессов разрушения хряща и стимулируя регенерацию ткани. Введение экзогенного глюкозамина усиливает выработку хрящевого матрикса и обеспечивает неспецифическую защиту от химического повреждения хряща. Другой возможной функцией глюкозамина является защита поврежденного хряща от метаболического разрушения, вызываемого нестероидными противовоспалительными препаратами (НПВП) и глюкокортикостероидами (ГКС), а также собственное умеренное противовоспалительное действие. Хондроитин сульфат натрия, независимо от того, всасывается ли он в интактной форме или же в виде отдельных компонентов, служит дополнительным субстратом для образования здорового хрящевого матрикса. Стимулирует образование гиалуронона, синтез протеогликанов и коллагена типа II, а также защищает гиалуронон от ферментативного расщепления (путем подавления активности гиалуронидазы) и от повреждающего действия свободных радикалов; поддерживает вязкость синовиальной жидкости, стимулирует механизмы репарации хряща и подавляет активность тех ферментов (эластаза, гиалуронидаза), которые расщепляют хрящ. При лечении остеоартрита облегчает симптомы заболевания и уменьшает потребность в НПВП.
Показания к применению
Комбинация Глюкозамина и Хондроитина рекомендуется взрослым и пожилым лицам в комплексном лечении заболеваний опорно-двигательного аппарата и других состояний, сопровождающихся дегенеративно-дистрофическими изменениями тканей суставного хряща и соединительной ткани: остеоартроз суставов I-III степени, в т.ч. крупных суставов (гонартроз), остеоартрит; остеохондроз позвоночника; пародонтопатии; плечелопаточный периартрит; спондиллез; хондромаляция надколенника; деформирование суставов (подвывихи, анкилозы); повышенная функциональная нагрузка на суставы (избыточный вес, физические нагрузки); профилактика заболеваний суставов в пожилом возрасте; для уменьшения последствий переломов, ускорения образования костной мозоли.
Противопоказания
Гиперчувствительность к глюкозамину, хондроитину или любому другому компоненту препарата; выраженные нарушения функции почек (для приема внутрь); беременность и грудное вскармливание; дети младше 12 лет. Препараты Глюкозамина и Хондроитина применяют с осторожностью: кровотечения или склонность к кровотечениям.
Применение при беременности и в период грудного вскармливания
Препарат противопоказан при беременности и лактации.
Способ применения и дозы
Глюкозамин и Хондроитин в капсулах/таблетках. Назначают внутрь, взрослым и детям старше 15 лет, перед едой, запивая небольшим количеством воды. Оптимальный режим дозирования определяет врач. Обычно, в течение первых 3-х недель приема препараты назначают из расчета - 1000-1500 мг глюкозамина гидрохлорида + 1000-1200 мг хондроитина сульфата в сутки, разделенные на 2-3 приема. В течение последующих недель и месяцев - по 500-1000 мг глюкозамина гидрохлорида + 500-800 мг хондроитина сульфата в сутки, разделенные на 2 приема. Облегчение боли и восстановление хрящевой ткани происходит не сразу, поэтому курс приема должен быть длительным. Минимальный курс приема составляет 3 месяца. Устойчивый лечебный эффект достигается при приеме не менее 6 месяцев. Глюкозамин и Хондроитин в составе мази/крема. Применяют наружно; наносят тонким слоем на неповрежденную кожу над участком поражения 2-3 раза в день, втирая массажными движениями в течение 2-3 минуты, до впитывания. Длительность применения - до 6 месяцев. Рекомендуется совместное использование крема/мази и капсул/таблеток для достижения оптимальной концентрации активных веществ в суставах.
Побочное действие
Может наблюдаться при передозировке или гиперчувствительности к компонентам препаратов: нарушения функции ЖКТ (тошнота, боль в эпигастрии, метеоризм, диарея/запор), головокружение, аллергические реакции.
Передозировка
Симптомы: случаи передозировки неизвестны. ; Лечение промывание желудка, симптоматическая терапия.
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