Состав на 100 мл сиропа
Действующее вещество:
Инозин пранобекс - 5,00 г
Вспомогательные вещества:
Сахароза - 65,00 г
Глицерол - 5,00 г
Метилпарагидроксибензоат - 0,18 г
Пропилпарагидроксибензоат - 0,02 г
Цитрусовый ароматизатор - 0,50 г
Вода очищенная - до 100 мл
Описание
Прозрачная, слегка желтоватая жидкость с характерным запахом.
Фармакологические свойства
Иммуностимулирующее средство, обладающее противовирусным действием. Представляет собой комплекс, содержащий инозин и соль пара-ацетамидобензойной кислоты с N,N-диметиламино-2-пропанолом в молярном соотношении 1:3.
Эффективность комплекса определяется присутствием инозина, второй компонент повышает его доступность для лимфоцитов. Нормомед® блокирует размножение вирусных частиц путем повреждения генетического аппарата, стимулирует активность макрофагов, пролиферацию лимфоцитов и образование цитокинов. Второй компонент повышает доступность препарата Нормомед® для лимфоцитов. Уменьшает клинические проявления вирусных заболеваний, ускоряет реконвалесценцию, повышает резистентность организма.
При назначении препарата Нормомед® в качестве вспомогательного лекарственного средства при инфекционном поражении слизистых оболочек и кожи, вызванных вирусом Herpes simplex, происходит более быстрое заживление пораженной поверхности, чем при лечении традиционным способом. Реже возникают новые пузырьки, отеки, эрозии и рецидивы болезни. При своевременном применении препарата сокращается частота возникновения вирусных инфекций, снижается длительность и тяжесть заболевания.
Показания к применению
Лечение гриппа и других ОРВИ в составе комплексной терапии.
Лечение лабиального герпеса (Herpes simplex) в составе комплексной терапии.
Противопоказания
повышенная чувствительность к инозину пранобексу и другим компонентам препарата;
подагра;
мочекаменная болезнь;
хроническая почечная недостаточность;
аритмии;
беременность;
период кормления грудью;
детский возраст до 3 лет (масса тела до 15-20 кг).
Применение при беременности и в период грудного вскармливания
Противопоказан беременным и женщинам, кормящим грудью, т.к. безопасность препарата не исследовалась.
Способ применения и дозы
Внутрь, после еды, запивая небольшим количеством воды, через равные промежутки времени (8 или 6 ч) 3-4 раза в сутки.
Взрослые и дети старше 12 лет: По 20 мл сиропа 3-4 раза в сутки.
Дети от 3 до 12 лет: 50 мг на 1 кг массы тела в сутки, разделенные на 3-4 приема.
Для детей старше 3 лет препарат назначается в соответствии с таблицей.
Масса тела Разовая доза при приеме 3 раза в сутки Максимальная суточная доза
15 - 20 кг 5 - 6,5 мл 15 - 20 мл/сут
21 - 30 кг 7 - 10 мл 21 - 30 мл/сут
31 - 40 кг 10 - 13 мл 31 - 40 мл/сут
41 - 50 кг 13,5 - 16,5 мл 41 - 50 мл/сут
При гриппе и других ОРВИ лечение продолжается от 5 до 14 дней. После исчезновения симптомов лечение следует продолжить в течение 1-2 дней.
При лабиальном герпесе лечение продолжается от 5 до 10 дней до исчезновения симптомов инфекции.
Особые группы пациентов
Применение у пожилых пациентов. Необходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста.
Длительность лечения без консультации с врачом не более 5 дней. Решение о продолжении терапии препаратом более 5 дней принимается лечащим врачом на основании клинической картины заболевания.
Применяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции.
Побочное действие
Побочные действия определяются следующим образом: часто — >1/100 и <1/10; и нечасто — >1/1000 и <1/100.
Со стороны нервной системы: часто - головная боль, головокружение, утомляемость, плохое самочувствие; нечасто - нервозность, сонливость, бессонница.
Со стороны желудочно-кишечного тракта: часто - снижение аппетита, тошнота, рвота, боль в эпигастрии; нечасто - диарея, запор.
Со стороны гепатобилиарной системы: часто - повышение активности печеночных ферментов, щелочной фосфатазы.
Со стороны кожи и подкож-но-жировой клетчатки: часто - зуд, сыпь.
Со стороны почек и мочевыводящих путей: нечасто - полиурия.
Аллергические реакции: нечасто - пятнисто-папулезная сыпь, крапивница, ангионевротический отек.
Общие расстройства: часто - боль в суставах, обострение подагры.
Лабораторные и инструментальные данные: часто - повышение концентрации азота мочевины крови.
Если у Вас отмечаются побочные эффекты, указанные в инструкции, или они усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.
Передозировка
При передозировке показано промывание желудка, симптоматическая терапия.
Взаимодействие с другими лекарственными средствами
Иммунодепрессанты ослабляют иммуностимулирующий эффект препарата.
Препарат следует применять с осторожностью пациентам, принимающим одновременно ингибиторы ксантиноксидазы (аллопуринол) или петлевые диуретики (фуросемид, торасемид, этакриновая кислота), так как это может приводить к повышению концентрации мочевой кислоты в сыворотке крови.
Совместное применение препарата с зидовудином приводит к увеличению концентрации зидовудина в плазме крови и удлиняет его Т1/2. Таким образом, при совместном применении препарата с зидовудином может потребоваться коррекция дозы зидовудина.
Если Вы применяете вышеперечисленные лекарственные препараты или другие лекарственные препараты (в том числе безрецептурные) перед применением препарата Нормомед® проконсультируйтесь с врачом.
Особые указания
Нормомед®, как и другие противовирусные средства, наиболее эффективен при острых вирусных инфекциях, если лечение начато на ранней стадии болезни (лучше с первых суток).
Поскольку инозин выводится из организма в форме мочевой кислоты, при назначении препарата одновременно с препаратами, увеличивающими концентрацию мочевой кислоты или препаратами, нарушающими функцию почек, необходимо контролировать концентрацию мочевой кислоты в сыворотке крови.
У пожилых пациентов чаще, чем у пациентов среднего возраста, происходит повышение концентрации мочевой кислоты в сыворотке крови и в моче.
Пациенты со значительно повышенной концентрацией мочевой кислоты в организме могут одновременно принимать препараты, понижающие ее концентрацию.
Нормомед® следует с осторожностью применять у пациентов с острой печеночной недостаточностью, поскольку препарат подвергается метаболизму в печени.
Сохраняйте инструкцию. Она может понадобиться вновь. Если у Вас возникли вопросы, обратитесь к врачу.
Условия хранения
Хранить в защищенном от света месте при температуре от 15 до 25 °С.
Хранить в недоступном для детей месте.
Срок годности
3 года. Срок годности после первого вскрытия флакона – 3 месяца.
Не использовать после окончания срока, указанного на упаковке.
Для описания товара использована информация от партнера 36.6
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Представляет собой комплекс, содержащий инозин и соль пара-ацетамидобензойной кислоты с N,N-диметиламино-2-пропанолом в молярном соотношении 1:3.\u003cbr /\u003e\nЭффективность комплекса определяется присутствием инозина, второй компонент повышает его доступность для лимфоцитов. Нормомед® блокирует размножение вирусных частиц путем повреждения генетического аппарата, стимулирует активность макрофагов, пролиферацию лимфоцитов и образование цитокинов. Второй компонент повышает доступность препарата Нормомед® для лимфоцитов. Уменьшает клинические проявления вирусных заболеваний, ускоряет реконвалесценцию, повышает резистентность организма.\u003cbr /\u003e\nПри назначении препарата Нормомед® в качестве вспомогательного лекарственного средства при инфекционном поражении слизистых оболочек и кожи, вызванных вирусом Herpes simplex, происходит более быстрое заживление пораженной поверхности, чем при лечении традиционным способом. Реже возникают новые пузырьки, отеки, эрозии и рецидивы болезни. При своевременном применении препарата сокращается частота возникновения вирусных инфекций, снижается длительность и тяжесть заболевания."}}]},{"id":4,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Лечение гриппа и других ОРВИ в составе комплексной терапии.\u003cbr /\u003e\nЛечение лабиального герпеса (Herpes simplex) в составе комплексной терапии."}}]},{"id":5,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"list","data":{"style":"unordered","items":["повышенная чувствительность к инозину пранобексу и другим компонентам препарата;\u003cbr /\u003e","подагра;\u003cbr /\u003e","мочекаменная болезнь;\u003cbr /\u003e","хроническая почечная недостаточность;\u003cbr /\u003e","аритмии;\u003cbr /\u003e","беременность;\u003cbr /\u003e","период кормления грудью;\u003cbr /\u003e","детский возраст до 3 лет (масса тела до 15-20 кг)."]}}]},{"id":6,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Противопоказан беременным и женщинам, кормящим грудью, т.к. безопасность препарата не исследовалась."}}]},{"id":7,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Внутрь, после еды, запивая небольшим количеством воды, через равные промежутки времени (8 или 6 ч) 3-4 раза в сутки.\u003cbr /\u003e\n\u003cbr /\u003e\nВзрослые и дети старше 12 лет: По 20 мл сиропа 3-4 раза в сутки.\u003cbr /\u003e\nДети от 3 до 12 лет: 50 мг на 1 кг массы тела в сутки, разделенные на 3-4 приема.\u003cbr /\u003e\nДля детей старше 3 лет препарат назначается в соответствии с таблицей.\u003cbr /\u003e\nМасса тела\tРазовая доза при приеме 3 раза в сутки\tМаксимальная суточная доза\u003cbr /\u003e\n15 - 20 кг \t5 - 6,5 мл\t 15 - 20 мл/сут\u003cbr /\u003e\n21 - 30 кг\t 7 - 10 мл\t 21 - 30 мл/сут\u003cbr /\u003e\n31 - 40 кг\t 10 - 13 мл\t 31 - 40 мл/сут\u003cbr /\u003e\n41 - 50 кг\t 13,5 - 16,5 мл\t 41 - 50 мл/сут\u003cbr /\u003e\n\u003cbr /\u003e\nПри гриппе и других ОРВИ лечение продолжается от 5 до 14 дней. После исчезновения симптомов лечение следует продолжить в течение 1-2 дней.\u003cbr /\u003e\nПри лабиальном герпесе лечение продолжается от 5 до 10 дней до исчезновения симптомов инфекции.\u003cbr /\u003e\n\u003cbr /\u003e\nОсобые группы пациентов\u003cbr /\u003e\nПрименение у пожилых пациентов. Необходимости в коррекции дозы нет, препарат применяется так же, как у пациентов среднего возраста.\u003cbr /\u003e\nДлительность лечения без консультации с врачом не более 5 дней. Решение о продолжении терапии препаратом более 5 дней принимается лечащим врачом на основании клинической картины заболевания.\u003cbr /\u003e\nПрименяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции."}}]},{"id":8,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Побочные действия определяются следующим образом: часто — \u003e1/100 и \u003c1/10; и нечасто — \u003e1/1000 и \u003c1/100.\u003cbr /\u003e\nСо стороны нервной системы: часто - головная боль, головокружение, утомляемость, плохое самочувствие; нечасто - нервозность, сонливость, бессонница.\u003cbr /\u003e\nСо стороны желудочно-кишечного тракта: часто - снижение аппетита, тошнота, рвота, боль в эпигастрии; нечасто - диарея, запор.\u003cbr /\u003e\nСо стороны гепатобилиарной системы: часто - повышение активности печеночных ферментов, щелочной фосфатазы.\u003cbr /\u003e\nСо стороны кожи и подкож-но-жировой клетчатки: часто - зуд, сыпь.\u003cbr /\u003e\nСо стороны почек и мочевыводящих путей: нечасто - полиурия.\u003cbr /\u003e\nАллергические реакции: нечасто - пятнисто-папулезная сыпь, крапивница, ангионевротический отек.\u003cbr /\u003e\nОбщие расстройства: часто - боль в суставах, обострение подагры.\u003cbr /\u003e\nЛабораторные и инструментальные данные: часто - повышение концентрации азота мочевины крови.\u003cbr /\u003e\nЕсли у Вас отмечаются побочные эффекты, указанные в инструкции, или они усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."}}]},{"id":9,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При передозировке показано промывание желудка, симптоматическая терапия."}}]},{"id":10,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Иммунодепрессанты ослабляют иммуностимулирующий эффект препарата.\u003cbr /\u003e\nПрепарат следует применять с осторожностью пациентам, принимающим одновременно ингибиторы ксантиноксидазы (аллопуринол) или петлевые диуретики (фуросемид, торасемид, этакриновая кислота), так как это может приводить к повышению концентрации мочевой кислоты в сыворотке крови.\u003cbr /\u003e\nСовместное применение препарата с зидовудином приводит к увеличению концентрации зидовудина в плазме крови и удлиняет его Т1/2. 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