Холина альфосцерат как носитель холина и предшественник фосф... Инструкция
Показания к применению
Психоорганический синдром на фоне инволюционных и дегенеративных процессов в головном мозге, последствия цереброваскулярной недостаточности или первичные и вторичные когнитивные нарушения у пожилых, характеризующиеся нарушением памяти, спутанностью сознания, дезориентации, снижением мотивации и инициативности, снижением концентрации внимания. Нарушения ...
Повышенная чувствительность к холина альфосцерату или к компонентам препарата, а также к лекарственным средствам со схожей химической структурой. Беременность и период грудного вскармливания. Детский возраст до 18 лет.
Полигидрат альфосцерата холина, вода для инъекций.
Описание
Холина альфосцерат - ноотропное средство, применяемое при лечении патологий мозга.
Фармакологические свойства
Холина альфосцерат как носитель холина и предшественник фосфатидилхолина имеет потенциальную способность предотвращать и корректировать биохимические повреждения, которые имеют особое значение среди патогенетических факторов психоорганического инволюционного синдрома, то есть может влиять на снижение холинергической передачи и поврежденный фосфолипидный состав оболочек нервных клеток. Химическая структура холина альфосцерат (содержащая 40,5 % холина) имеет свойство метаболической защиты и обеспечивает высвобождение активного вещества – холина в тканях головного мозга. Холина альфосцерат положительно влияет на функции памяти и познавательные способности, а также на показатели эмоционального состояния и поведения, ухудшение которых было вызвано развитием инволюционной патологии мозга.
Показания к применению
Психоорганический синдром на фоне инволюционных и дегенеративных процессов в головном мозге, последствия цереброваскулярной недостаточности или первичные и вторичные когнитивные нарушения у пожилых, характеризующиеся нарушением памяти, спутанностью сознания, дезориентации, снижением мотивации и инициативности, снижением концентрации внимания. Нарушения поведения и аффективной сферы в старческом возрасте: эмоциональная лабильность, повышенная раздражительность, снижение интереса. Старческая псевдомеланхолия.
Противопоказания
Повышенная чувствительность к холина альфосцерату или к компонентам препарата, а также к лекарственным средствам со схожей химической структурой. Беременность и период грудного вскармливания. Детский возраст до 18 лет.
Применение при беременности и в период грудного вскармливания
Противопоказан при беременности и в период лактации.
Способ применения и дозы
Препарат вводят внутримышечно или внутривенно (капельно, медленно) в дозе 1000 мг (1 ампула) в сутки, в течение 10 дней. При необходимости и в случае хорошей переносимости доза препарата и длительность лечения могут быть увеличены лечащим врачом в зависимости от клинической картины, особенностей течения заболевания, возраста и переносимости препарата. При появлении нежелательных реакций возможно снижение дозы препарата.
Побочное действие
Со стороны пищеварительной системы: тошнота (которая главным образом является следствием вторичной допаминергической активации), боль в животе. Со стороны нервной системы: кратковременная спутанность сознания (в этом случае необходимо уменьшить дозу препарата).
Передозировка
Возможно усиление выраженности дозозависимых побочных эффектов. Лечение: симптоматическая терапия. Эффективность диализа не установлена.
Особые указания
Тошнота может являться следствием допаминергической активации. Эффективность и безопасность у детей до 18 лет не установлена.
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