Повышенная чувствительность к аморолфину или любому из компонентов препарата.
Применение при беременности и в период грудного вскармливания
Ввиду ограниченности данных о применении аморолфина у беременных и кормящих женщин, применение препарата при беременности и в период грудного вскармливания не рекомендуется.
Способ применения и дозы
Наружно. Наносить на пораженные ногти пальцев рук или ног 1-2 раза в неделю следующим образом: 1. До применения препарата удалить по возможности пораженные участки ногтя (особенно с его поверхности) с помощью прилагаемой пилки для ногтей. ; 2. Затем поверхность ногтя очистить и обезжирить прилагаемым тампоном, смоченным спиртом. Перед каждым последующим применением препарата необходимо также проводить обработку пораженных ногтей пилкой и затем удалять оставшийся слой лака спиртовым тампоном. ; 3. Опустить аппликатор во флакон с лаком и затем аккуратно вынуть его, не стирая излишки лака о горлышко флакона. ; 4. С помощью аппликатора нанести лак ровным слоем на всю поверхность пораженного ногтя. Вышеописанную процедуру повторить для каждого пораженного ногтя. ; 5. Дать лаку высохнуть в течение 3-х минут. ; 6. Протереть аппликатор тампоном, использованным для очистки ногтя, избегая при этом контакта обработанных ногтей и ; тампона. Плотно закрыть флакон сразу же по окончании процедуры. Использованный тампон выбросить. ; Нанесение декоративного лака для ногтей возможно не ранее, чем через 10 минут после применения лака для ногтей Лоцерил. ; При повторном применении лака Лоцерил, необходимо аккуратно удалить с ногтей оставшийся декоративный лак, затем с помощью прилагаемых пилок обработать пораженные участки ногтей и удалить оставшийся слой лака спиртовыми тампонами. ; По окончании процедуры тщательно вымойте руки. В случае, если лак наносился на ногти на руках, дождитесь сначала его полного высыхания. ; После высыхания лака разрешается регулярное мытье рук и ног с использованием мыла. ; Лечение следует продолжать до регенерации ногтя и полного излечения пораженного участка. ; Средняя длительность лечения составляет 6 месяцев для ногтей на руках и 9-12 месяцев для ногтей на ногах. ; Ввиду медленного роста ногтевых пластин первые признаки улучшения могут стать ; заметными только после 2-3 месяцев применения препарата. При отсутствии признаков улучшения по истечении 3 месяцев рекомендуется проконсультироваться с врачом.
Побочное действие
При применении препарата Лоцерил нежелательные реакции отмечаются редко. Такие повреждения ногтей, как изменение цвета, разрушение ногтевых пластин, ломкость ногтей, могут быть следствием грибкового поражения ногтей. Все нежелательные реакции, отмеченные при ; применении препарата Лоцерил, представлены в таблице ниже в соответствии с принятой классификацией по системам ; органов и частоте встречаемости: очень часто (≥ 1/10), часто (≥ 1/100 - < 1/10), нечасто (≥ 1/1000 - < 1/100), редко (≥ 1/10000 - <1/1000), очень редко (< 1/10 ; 000), частота неизвестна (не может быть оценена на основании имеющихся данных): Нарушения со стороны кожи и подкожных тканей ; Редко (≥ 1/10000 - <1/1000) Повреждение ногтей, изменение цвета, онихоклазия (ломкость ногтевой пластинки), онихорексис (хрупкость ногтевой пластинки) ; Очень редко (< 1/10000) Ощущение жжения кожи ; Частота неизвестна Эритема, зуд, контактный дерматит, крапивница, образование волдырей ; Если любые из указанных в инструкции побочных эффектов усугубляются, или отмечаются любые другие побочные эффекты, не указанные в инструкции, следует немедленно сообщить об этом врачу.
Передозировка
При наружном применении препарата развитие системных признаков передозировки не ожидается. При случайном проглатывании препарата необходимо провести соответствующую симптоматическую терапию.
Особые указания
Пилки, использованные для обработки пораженных ногтей, не следует использовать для обработки здоровых ногтей; ; лица, работающие с органическими растворителями, должны надевать непроницаемые перчатки для защиты ногтей, покрытых лаком; ; во время лечения следует избегать использования накладных искусственных ногтей; ; препарат содержит этанол, поэтому слишком частое или неправильное его нанесение может привести к появлению раздражения или сухости кожи вокруг ногтя; ; тампон содержит легко воспламеняющееся вещество. ; Следует избегать попадания лака в глаза, уши и на слизистые оболочки. При попадании лака в глаза необходимо немедленно промыть их водой. Пациентам с состояниями, предрасполагающими к развитию грибковых поражений ногтей (нарушение периферического кровообращения, сахарный диабет, иммунодефициты), а также пациентам с дистрофией ногтя или разрушенной ногтевой пластинкой, псориазом или ; другими хроническими заболеваниями кожи следует обратиться к врачу. ; В случае, если разрушению или грибковому поражению подвержено более 2/3 ногтевой пластинки, необходимо также обратиться к врачу для назначения сопутствующей пероральной терапии.
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Оказывает фунгистатическое и фунгицидное действие, обусловленное повреждением цитоплазматической мембраны гриба путем нарушения биосинтеза стеролов. Снижается содержание эргостерола, накапливается содержание атипичных стерических неплоских стеролов. Обладает широким спектром действия. Высокоактивен в отношении как наиболее распространенных, так и редких возбудителей грибковых поражений ногтей: Дерматофитов: Trichophyton spp., Microsporum spp., Epidermophyton spp. ; Дрожжевых грибов: Candida spp., Cryptococcus spp., Malassezia spp. (Pityrosporum spp.) ; Плесневых грибов: Alternaria spp., Scopulariopsis spp., Hendersonula spp. ; Грибов из семейства Dematiaceae: Cladopsorium spp., Fonsecaea spp., Wangiella spp. ; Диморфных грибов: Coccidioides spp., Histoplasma spp., Sporothrix spp."}}]},{"id":3,"name":"Показания к применению","slug":"indications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"лечение грибковых поражений ногтей, вызванных дерматофитами, дрожжевыми и плесневыми грибами; профилактика грибковых поражений ногтей."}}]},{"id":4,"name":"Противопоказания","slug":"contraindications","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к аморолфину или любому из компонентов препарата."}}]},{"id":5,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Ввиду ограниченности данных о применении аморолфина у беременных и кормящих женщин, применение препарата при беременности и в период грудного вскармливания не рекомендуется."}}]},{"id":6,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Наружно. Наносить на пораженные ногти пальцев рук или ног 1-2 раза в неделю следующим образом: 1. До применения препарата удалить по возможности пораженные участки ногтя (особенно с его поверхности) с помощью прилагаемой пилки для ногтей. ; 2. Затем поверхность ногтя очистить и обезжирить прилагаемым тампоном, смоченным спиртом. Перед каждым последующим применением препарата необходимо также проводить обработку пораженных ногтей пилкой и затем удалять оставшийся слой лака спиртовым тампоном. ; 3. Опустить аппликатор во флакон с лаком и затем аккуратно вынуть его, не стирая излишки лака о горлышко флакона. ; 4. С помощью аппликатора нанести лак ровным слоем на всю поверхность пораженного ногтя. Вышеописанную процедуру повторить для каждого пораженного ногтя. ; 5. Дать лаку высохнуть в течение 3-х минут. ; 6. Протереть аппликатор тампоном, использованным для очистки ногтя, избегая при этом контакта обработанных ногтей и ; тампона. Плотно закрыть флакон сразу же по окончании процедуры. Использованный тампон выбросить. ; Нанесение декоративного лака для ногтей возможно не ранее, чем через 10 минут после применения лака для ногтей Лоцерил. ; При повторном применении лака Лоцерил, необходимо аккуратно удалить с ногтей оставшийся декоративный лак, затем с помощью прилагаемых пилок обработать пораженные участки ногтей и удалить оставшийся слой лака спиртовыми тампонами. ; По окончании процедуры тщательно вымойте руки. В случае, если лак наносился на ногти на руках, дождитесь сначала его полного высыхания. ; После высыхания лака разрешается регулярное мытье рук и ног с использованием мыла. ; Лечение следует продолжать до регенерации ногтя и полного излечения пораженного участка. ; Средняя длительность лечения составляет 6 месяцев для ногтей на руках и 9-12 месяцев для ногтей на ногах. ; Ввиду медленного роста ногтевых пластин первые признаки улучшения могут стать ; заметными только после 2-3 месяцев применения препарата. При отсутствии признаков улучшения по истечении 3 месяцев рекомендуется проконсультироваться с врачом."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При применении препарата Лоцерил нежелательные реакции отмечаются редко. Такие повреждения ногтей, как изменение цвета, разрушение ногтевых пластин, ломкость ногтей, могут быть следствием грибкового поражения ногтей. Все нежелательные реакции, отмеченные при ; применении препарата Лоцерил, представлены в таблице ниже в соответствии с принятой классификацией по системам ; органов и частоте встречаемости: очень часто (≥ 1/10), часто (≥ 1/100 - \u003c 1/10), нечасто (≥ 1/1000 - \u003c 1/100), редко (≥ 1/10000 - \u003c1/1000), очень редко (\u003c 1/10 ; 000), частота неизвестна (не может быть оценена на основании имеющихся данных): Нарушения со стороны кожи и подкожных тканей ; Редко (≥ 1/10000 - \u003c1/1000) Повреждение ногтей, изменение цвета, онихоклазия (ломкость ногтевой пластинки), онихорексис (хрупкость ногтевой пластинки) ; Очень редко (\u003c 1/10000) Ощущение жжения кожи ; Частота неизвестна Эритема, зуд, контактный дерматит, крапивница, образование волдырей ; Если любые из указанных в инструкции побочных эффектов усугубляются, или отмечаются любые другие побочные эффекты, не указанные в инструкции, следует немедленно сообщить об этом врачу."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При наружном применении препарата развитие системных признаков передозировки не ожидается. 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