Отривин Комплекс Спрей, флакон, 10 мл, 0,6+0,5 мг/мл, для орошения, назальный, для взрослых

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Рекомендуется соблюдать осторожность при лечении пациентов, предрасположенных к носовым кровотечениям, с чувствительностью к адренергическим средствам, которые могут приводить к появлению таких симптомов, как нарушение сна, головокружение, тремор скелетной мускулатуры, аритмия, повышение АД; паралитической непроходимости кишечника и пациентов с муковисцидозом."}},{"type":"paragraph","data":{"text":"Рекомендуется соблюдать осторожность при применении препарата у пациента, имеющего в анамнезе реакции гиперчувствительности немедленного типа, включая крапивницу, ангионевротический отек, сыпь, бронхоспазм, отек гортани и анафилактические реакции."}},{"type":"paragraph","data":{"text":"Если у пациента одно из перечисленных заболеваний, перед приемом препарата он должен обязательно проконсультироваться с врачом."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Применение препарата при беременности и в период грудного вскармливания противопоказано."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Интраназально."}},{"type":"paragraph","data":{"text":"Для \u003cb\u003eпациентов в возрасте старше 18 лет:\u003c/b\u003e по 1 впрыскиванию в каждый носовой ход 3 раза/сут. Перерыв между повторным применением должен составлять минимум 6 ч. Суточная доза не должна превышать более 3 впрыскиваний в каждый носовой ход."}},{"type":"paragraph","data":{"text":"Препарат применяют не более 7 дней без консультации врача."}},{"type":"paragraph","data":{"text":"Рекомендуется прекратить лечение сразу после купирования симптомов, даже если это произошло ранее, чем через 7 дней (максимальная продолжительность терапии), с целью минимизации риска нежелательных явлений."}},{"type":"paragraph","data":{"text":"Длительное применение ксилометазолина может вызвать отек слизистой оболочки носа и повышение секреции, что обусловлено развитием повышенной чувствительности клеток к действующим веществам препарата, так называемый обратный эффект."}},{"type":"paragraph","data":{"text":"1 впрыскивание (140 мкл) препарата Отривин Комплекс содержит около 70 мкг ксилометазолина гидрохлорида и 84 мкг ипратропия бромида."}},{"type":"paragraph","data":{"text":"\u003cb\u003eПрименение в пожилом возрасте: \u003c/b\u003eопыт применения препарата у \u003cb\u003eпациентов старше 70 лет\u003c/b\u003e ограничен."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Определение частоты побочных реакций: очень часто (≥10); часто (≥1/100, <1/10); нечасто (≥1/1000, <1/100); редко (\u003cb\u003e≥\u003c/b\u003e1/10 000, <1/1000); очень редко (<1/10 000), включая отдельные сообщения и реакции с неизвестной частотой (не может быть рассчитана на основании доступных данных)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны иммунной системы:\u003c/i\u003e частота неизвестна - гиперчувствительность."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны нервной системы:\u003c/i\u003e часто - нарушение вкуса, головная боль; нечасто - нарушение обоняния, головокружение, тремор; очень редко - бессонница."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны органа зрения:\u003c/i\u003e нечасто - раздражение глаз, сухость глаз; частота неизвестна - повышение внутриглазного давления, мидриаз, боль в глазах, фотопсия, ухудшение состояния при закрытоугольной глаукоме, нарушение четкости зрительного восприятия, расширение зрачка, гало эффект (наличие в поле зрения радужных кругов вокруг источника света)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны сердца:\u003c/i\u003e нечасто - учащенное сердцебиение, наджелудочковая тахикардия; очень редко - аритмичный пульс; частота неизвестна - мерцательная аритмия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны дыхательной системы:\u003c/i\u003e очень часто - носовое кровотечение, раздражение и/или сухость слизистой оболочки носоглотки; часто - ощущение жжения, покалывания, чихание, назальная гиперсекреция; заложенность носа (при частом и/или длительном применении препарата), сухость в горле, першение в горле, риналгия; нечасто - носовая язва, чихание, боль в глотке, кашель, дисфония; редко - насморк; частота неизвестна - дискомфорт в области околоносовых пазух, спазм гортани, отек глотки."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны пищеварительной системы:\u003c/i\u003e часто - сухость во рту; нечасто - диспепсия, тошнота; частота неизвестна - затрудненное глотание."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны кожи и подкожных тканей:\u003c/i\u003e частота неизвестна - зуд, кожная сыпь, крапивница."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны мочевыделительной системы:\u003c/i\u003e частота неизвестна - затрудненное мочеиспускание."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОбщие реакции:\u003c/i\u003e нечасто - дискомфорт, утомляемость; частота неизвестна - дискомфорт в грудной клетке, жажда."}},{"type":"paragraph","data":{"text":"\u003ci\u003eАллергические реакции:\u003c/i\u003e редко - системные аллергические реакции (анафилактическая реакция, ангионевротический отек языка, губ и лица, ларингоспазм)."}},{"type":"paragraph","data":{"text":"Если любые из указанных выше побочных эффектов усугубляются, или пациент заметил любые другие побочные эффекты, он должен сообщить об этом врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"При назальном применении препарата Отривин Комплекс острая передозировка маловероятна, т.к. всасывание препарата крайне незначительно."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы:\u003c/i\u003e в случае передозировки ксилометазолина для клинической картины характерны тошнота, потоотделение, понижение температуры тела, головная боль, брадикардия, нарушение аккомодации, артериальная гипертензия, угнетение дыхания, кома. Артериальная гипертензия может смениться гипотензией."}},{"type":"paragraph","data":{"text":"При чрезмерном использовании ипратропия бромида передозировка маловероятна в связи с крайне незначительным всасыванием вещества в кровь, но могут развиться сухость во рту, затруднение аккомодации, тахикардия."}},{"type":"paragraph","data":{"text":"Значительная передозировка может вызвать симптомы, связанные с холинолитическим действием препарата со стороны ЦНС, включая галлюцинации, для устранения которых назначают ингибиторы холинэстеразы."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение:\u003c/i\u003e соответствующие поддерживающие меры должны приниматься при любых подозрениях на передозировку, при необходимости показано незамедлительное симптоматическое лечение под наблюдением врача. Симптоматическую терапию необходимо проводить под наблюдением врача. Эти меры должны включать наблюдение за пациентом в течение 6 ч. В случае тяжелого отравления с остановкой сердца реанимационные действия должны продолжаться не менее 1 часа."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Препарат несовместим с одновременным приемом ингибиторов МАО, три- и тетрациклических антидепрессантов, а также в случае приема указанных препаратов в течение предшествующих 2 недель."}},{"type":"paragraph","data":{"text":"Симпатомиметические препараты вызывают высвобождение катехоламинов, в т.ч. норадреналина, обладающего сосудосуживающим эффектом, вследствие чего повышается АД. При значительном повышении АД лечение препаратом Отривин Комплекс следует отменить, провести симптоматическое лечение."}},{"type":"paragraph","data":{"text":"Применение с три- и тетрациклическими антидепрессантами может усилить симпатомиметический эффект ксилометазолина."}},{"type":"paragraph","data":{"text":"При сопутствующем назначении других препаратов, обладающих антихолинергической активностью, возможно усиление антихолинергического эффекта ипратропия бромида."}},{"type":"paragraph","data":{"text":"Вышеуказанное взаимодействие изучалось индивидуально для обоих активных веществ, входящих в состав препарата Отривин Комплекс. В комбинации для обоих активных веществ вышеуказанное взаимодействие не изучалось."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Перед применением необходимо очистить носовые ходы. Не следует применять в течение длительного времени, например, при хроническом рините."}},{"type":"paragraph","data":{"text":"Не допускать попадания препарата в глаза или вокруг глаз. В случае попадания может отмечаться временная нечеткость зрения, раздражение, боль, покраснение глаз, возможно развитие обострения закрытоугольной глаукомы. Следует обильно промыть глаза холодной водой в случае попадания в них препарата и обратиться к врачу при боли в глазах или помутнении зрения."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"  При применении препарата Отривин Комплекс отмечались случаи нарушения зрения (включая нечеткость зрения и расширение зрачка), головокружения и утомляемости. Пациентов следует предупредить о том, что при появлении подобных симптомов они должны воздержаться от вождения транспортных средств, управления механизмами, а также от выполнения действий, в случае которых подобные симптомы могут повлечь за собой риск для самих пациентов и для других людей.  "}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ci\u003e\u003cb\u003eСпрей назальный\u003c/b\u003e\u003c/i\u003e в виде прозрачного, бесцветного или слегка окрашенного раствора, практически без запаха.  "}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"Срок годности - 3 года"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Препарат отпускается без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/firm/4838\"\u003eГлаксоСмитКляйн Хелскер, АО\u003c/a\u003e (Россия)  "}}]}],"source":null},"description_toggle":false,"short_description":"Ксилометазолинотносится к группе местных сосудосуживающих средств (деконгестантов) c альфа-адреномиметическим действием, вызывает сужение кровеносных сосудов слизистой оболочки носа, устраняя таким образом отек и гиперемию слизистой оболочки носоглотки. Снимает заложенность, облегчая носовое дыхание при ринитах.Ипратропия бромидобладает антихолинергическим эффектом. При интраназальном применении снижает назальную секрецию, останавливая течение из носа за счет конкурентного ингибирования холинергических рецепторов, расположенных в эпителии носовой полости. В терапевтических концентрациях не раздражает слизистую оболочку, не вызывает ее гиперемии. 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