1 таблетка содержит: Активное вещество: пропранолола гидрохлорид 10 мг.
Показания к применению
Артериальная гипертензия.
Стенокардия напряжения, нестабильная стенокардия.
Синусовая тахикардия (в т.ч. при гипертиреозе), наджелудочковая тахикардия.
Тахисистолическая форма мерцания предсердий.
Наджелудочковая и желудочковая экстрасистолия.
Эссенциальный тремор.
Профилактика мигрени .
Алкогольная абстиненция (ажитация и дрожание).
Тревожность.
Феохромоцитома (вспомогательное лечение).
Диффузно-токсический зоб и тиреотоксический криз (в качестве вспомогательного средства, в т.ч. при непереносимости тиреостатических препаратов).
Симпатоадреналовые кризы на фоне диэнцефального синдрома.
Противопоказания
Гиперчувствительность; AV блокада 5 ст.
синоатриальная блокада; синусовая брадикардия.
Применение при беременности и в период грудного вскармливания
Применение пропранолола при беременности возможно только в том случае, когда предполагаемая польза для матери превышает потенциальный риск для плода. При необходимости применения в этот период необходимо тщательное наблюдение за состоянием плода, за 48-72 ч до родов пропранолол следует отменить.; Следует иметь в виду, что возможно негативное влияние на плод: внутриутробная задержка роста, гипогликемия, брадикардия .; Пропранолол выделяется с грудным молоком. При необходимости применения в период лактации следует установить врачебное наблюдение за ребенком или прекратить грудное вскармливание.
Способ применения и дозы
При приеме внутрь режим дозирования индивидуальный. Начальная доза составляет 20 мг. Разовая доза - 40-80 мг, частота приема - 2-3 раза/сут. Максимальные дозы: 320 мг/сут.
Побочное действие
Со стороны ЦНС и периферической нервной системы; Повышенная утомляемость, слабость, головокружение, головная боль, сонливость или бессонница, яркие сновидения, депрессия, спутанность сознания , галлюцинации, тремор, нервозность, беспокойство. ; Со стороны органов чувств; Уменьшение секреции слезной жидкости (сухость и болезненность глаз). ; Со стороны сердечно-сосудистой системы; Синусовая брадикардия , AV блокада (вплоть до развития полной поперечной блокады и остановки сердца), аритмии , развитие (усугубление) хронической сердечной недостаточности , снижение АД, ортостатическая гипотензия, проявление ангиоспазма (усиление нарушения периферического кровообращения, похолодание нижних конечностей, синдром Рейно), боль в груди. ; Со стороны пищеварительной системы; Тошнота, рвота , дискомфорт в эпигастральной области, запор или диарея, нарушения функции печени (темная моча, желтушность склер или кожи, холестаз), изменения вкуса, повышение активности печеночных трансаминаз, ЛДГ. ; Со стороны дыхательной системы; Заложенность носа, бронхоспазм. ; Со стороны эндокринной системы; Изменение концентрации глюкозы крови (гипо- или гипергликемия). ; Со стороны системы кроветворения; Тромбоцитопения (необычные кровотечения и кровоизлияния), лейкопения. ; Дерматологические реакции; Усиление потоотделения, псориазоподобные кожные реакции, обострение симптомов псориаза. ; Аллергические реакции; Зуд, кожная сыпь, крапивница. ; Прочие; Боль в спине, артралгии, снижение потенции, синдром отмены (усиление приступов стенокардии, инфаркт миокарда, повышение АД ).
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