Гастал - комбинированный антацидный препарат для приема внутрь. Снижает повышенную кислотность желудочного сока до физиологического уровня и устраняет диспепсические расстройства за счет нейтрализации избытка соляной кислоты в желудке. Входящие в состав Гастала гидроксид магния и гидроксид алюминия обеспечивают быструю и длительную нейтрализацию, обусловливающую антацидный эффект.
Антацидное действие препарата проявляется сразу после приема таблеток Гастала и продолжается около 2 ч. 1 таблетка Гастала нейтрализует около 21.5 ммоль соляной кислоты. Гастал ингибирует действие пепсина, лизолецитина и желчных кислот, таким образом, также устраняя расстройства функции желудка.
Гастал помимо антацидного эффекта активирует защитные и регенеративные механизмы в слизистой оболочке желудка. Цитопротекторное действие, обусловленное ионами алюминия, включает стимулирование секреции слизи и гидрокарбоната натрия в желудке, накопление эпидермального фактора роста в очаге повреждения, увеличение концентрации фосфолипидов в желудке и другие механизмы.
Фармакокинетика
Гастал не оказывает системного действия у пациентов с нормальной функцией почек.
После взаимодействия с соляной кислотой желудочного сока, гидроксид алюминия реагирует с фосфатами и карбонатами в щелочной среде кишечника и выделяется с калом в виде нерастворимых солей. Гидроксид магния реагирует с соляной кислотой в желудочном соке с образованием хлорида магния, который оказывает осмотическое слабительное действие в тонком кишечнике. Магний также выводится с калом в виде нерастворимого карбоната.
Показания к применению
изжога (после приема лекарственных средств, алкоголя, кофе; погрешностей впитании, злоупотреблении никотином и т.д.);
эрозии слизистой оболочки желудка и верхних отделов ЖКТ;
рефлюкс-эзофагит;
грыжа пищеводного отверстия диафрагмы;
острый панкреатит, обострение хронического панкреатита (в составе комбинированной терапии);
бродильная или гнилостная диспепсия (в составе комбинированной терапии).
Противопоказания
хроническая почечная недостаточность;
болезнь Альцгеймера;
гипофосфатемия;
детский возраст до 6 лет;
гиперчувствительность.
С осторожностью
детский возраст до 12 лет; в период лактации и при беременности - только по назначению и под контролем врача.
Применение при беременности и в период грудного вскармливания
Как и при назначении всех других лекарственных препаратов, применение Гастала при беременности возможно только в особых случаях и только по рекомендации врача.
Способ применения и дозы
Внутрь. Таблетку следует постепенно рассасывать (не проглатывать целиком).
Взрослым рекомендуется принимать через 1 ч после приема пищи и перед сном 1-2 таб. 4-6 раз/сут, однако не более 8 таб. в течение 24 ч.
Продолжительность приема Гастала не должна превышать 2 недель.
Для профилактики Гастал применяют перед предполагаемым раздражающим воздействием на слизистую оболочку ЖКТ.
Аналогичные дозы рекомендуются при изжоге, независимо от приема пищи.
Для детей в возрасте 6-12 лет рекомендуется половина дозы, принятой для взрослых.
Побочное действие
Редко : аллергические реакции, тошнота, рвота, изменение вкусовых ощущений, диарея, запор.
Передозировка
Не зарегистрировано симптомов острой передозировки.
При длительном приеме в высоких дозах препаратов, содержащих алюминий и магний возможно развитие гипофосфатемии, гипокальциемии, гиперкальциурии, остеомаляции, остеопороза, гипермагниеми и гипералюминиемии, энцефалопатии, нефрокальциноза и нарушения функции почек. Возможно усиление побочных эффектов со стороны ЖКТ (запоры, диарея). У больных с сопутствующей почечной недостаточностью — жажда, снижение АД, гипорефлексия.
При появлении указанных симптомов следует проводить симптоматическое лечение.
Взаимодействие с другими лекарственными средствами
Интервал между приемом Гастала и других лекарственных средств должен составлять 1-2 ч.
Гастал усиливает активность леводопы и налидиксовой кислоты; снижает и замедляет абсорбцию тетрациклиновых антибиотиков, ципрофлокацина и офлоксацина, салицилатов, изониазида, напроксена, препаратов железа, сердечных гпикозидов, индометацина, аминазина, фенитоина, блокаторов Н2-гистаминовых рецепторов, бета-адрепоблокаторов, дифлунизала, жирорастворимых витаминов, непрямых антикоагулянтов, барбитуратов. М- холиноблокаторы, замедляя опорожнение желудка, усиливают и удлиняют действие препарата.
Особые указания
Пациентам с небольшой массой тела и детям применяются меньшие дозы и менее длительно.
Пациентам с нарушением функции почек не рекомендуется применение Гастала более длительное и в более высоких дозах, чем рекомендовано.
Непрерывный прием более 2-х недель - только после консультации врача.
Влияние на способность управлять автомобилем и движущимися механизмами
Применение препарата Гастал не оказывает влияния на способность к вождению автотранспорта и управлению другими механизмами.
Форма выпуска
Круглые таблетки от белого до кремового цвета с гладкой поверхностью и фаской.
Условия хранения
Хранить при температуре не выше 25°С.
Срок годности
Срок годности – 3 года. Не применять по истечении, срока годности.
Условия отпуска
Препарат разрешен к применению в качестве средства безрецептурного отпуска.
Для описания товара использована информация от партнера 36.6
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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110,0/112,0/112,0 мг,"}},{"type":"paragraph","data":{"text":"крахмал прежелатинизированный 32,0/32,0/32,0 мг,"}},{"type":"paragraph","data":{"text":"кремния диоксид коллоидный 2,0/2,0/2,0 мг,"}},{"type":"paragraph","data":{"text":"кроскармеллоза натрия (тип А) 50,0/50,0/50,0 мг,"}},{"type":"paragraph","data":{"text":"аспартам 2,5/2,0/2,0 мг,"}},{"type":"paragraph","data":{"text":"магния стеарат 6,0/6,0/6,0 мг,"}},{"type":"paragraph","data":{"text":"ароматизатор мятный 11890-71 (таблетки мятные) 6,0 мг или ароматизатор вишневый Е 9407963 (таблетки вишневые) 4,0 мг или ароматизатор апельсиновый 1013042 (таблетки апельсиновые) 4,0 мг."}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"\u003ci\u003e\u003cb\u003eТаблетки для рассасывания\u003c/b\u003e\u003c/i\u003e\u003cb\u003e\u003ci\u003e \u003c/i\u003e\u003c/b\u003eбелого или почти белого цвета, круглые с гладкой поверхностью и фаской, с мятным вкусом. "}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/pharm-group/61\"\u003eАнтацидное средство\u003c/a\u003e"}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Гастал - комбинированный антацидный препарат для приема внутрь. Снижает повышенную кислотность желудочного сока до физиологического уровня и устраняет диспепсические расстройства за счет нейтрализации избытка соляной кислоты в желудке. Входящие в состав Гастала гидроксид магния и гидроксид алюминия обеспечивают быструю и длительную нейтрализацию, обусловливающую антацидный эффект."}},{"type":"paragraph","data":{"text":"Антацидное действие препарата проявляется сразу после приема таблеток Гастала и продолжается около 2 ч. 1 таблетка Гастала нейтрализует около 21.5 ммоль соляной кислоты. Гастал ингибирует действие пепсина, лизолецитина и желчных кислот, таким образом, также устраняя расстройства функции желудка."}},{"type":"paragraph","data":{"text":"Гастал помимо антацидного эффекта активирует защитные и регенеративные механизмы в слизистой оболочке желудка. Цитопротекторное действие, обусловленное ионами алюминия, включает стимулирование секреции слизи и гидрокарбоната натрия в желудке, накопление эпидермального фактора роста в очаге повреждения, увеличение концентрации фосфолипидов в желудке и другие механизмы."}},{"type":"header","data":{"text":"Фармакокинетика","level":4}},{"type":"paragraph","data":{"text":"Гастал не оказывает системного действия у пациентов с нормальной функцией почек."}},{"type":"paragraph","data":{"text":"После взаимодействия с соляной кислотой желудочного сока, гидроксид алюминия реагирует с фосфатами и карбонатами в щелочной среде кишечника и выделяется с калом в виде нерастворимых солей. Гидроксид магния реагирует с соляной кислотой в желудочном соке с образованием хлорида магния, который оказывает осмотическое слабительное действие в тонком кишечнике. Магний также выводится с калом в виде нерастворимого карбоната."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"list","data":{"style":"ordered","items":["изжога (после приема лекарственных средств, алкоголя, кофе; погрешностей впитании, злоупотреблении никотином и т.д.);","состояния, сопровожающиеся повышенным кислотообразованием: гастриты, язвенная болезнь желудка и двенадцатиперстной кишки;","симптоматические язвы различного генеза;","эрозии слизистой оболочки желудка и верхних отделов ЖКТ;","рефлюкс-эзофагит;","грыжа пищеводного отверстия диафрагмы;","острый панкреатит, обострение хронического панкреатита (в составе комбинированной терапии);","бродильная или гнилостная диспепсия (в составе комбинированной терапии)."]}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"list","data":{"style":"ordered","items":["хроническая почечная недостаточность;","болезнь Альцгеймера;","гипофосфатемия;","детский возраст до 6 лет;","гиперчувствительность."]}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"детский возраст до 12 лет; в период лактации и при беременности - только по назначению и под контролем врача."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Как и при назначении всех других лекарственных препаратов, применение Гастала при беременности возможно только в особых случаях и только по рекомендации врача."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь. Таблетку следует постепенно рассасывать (не проглатывать целиком)."}},{"type":"paragraph","data":{"text":"\u003cb\u003eВзрослым\u003c/b\u003e рекомендуется принимать через 1 ч после приема пищи и перед сном 1-2 таб. 4-6 раз/сут, однако не более 8 таб. в течение 24 ч."}},{"type":"paragraph","data":{"text":"Продолжительность приема Гастала не должна превышать 2 недель."}},{"type":"paragraph","data":{"text":"Для профилактики Гастал применяют перед предполагаемым раздражающим воздействием на слизистую оболочку ЖКТ."}},{"type":"paragraph","data":{"text":"Аналогичные дозы рекомендуются при изжоге, независимо от приема пищи."}},{"type":"paragraph","data":{"text":"Для \u003cb\u003eдетей в возрасте 6-12 лет\u003c/b\u003e рекомендуется половина дозы, принятой для взрослых."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eРедко\u003c/i\u003e : аллергические реакции, тошнота, рвота, изменение вкусовых ощущений, диарея, запор. "}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Не зарегистрировано симптомов острой передозировки."}},{"type":"paragraph","data":{"text":"При длительном приеме в высоких дозах препаратов, содержащих алюминий и магний возможно развитие гипофосфатемии, гипокальциемии, гиперкальциурии, остеомаляции, остеопороза, гипермагниеми и гипералюминиемии, энцефалопатии, нефрокальциноза и нарушения функции почек. Возможно усиление побочных эффектов со стороны ЖКТ (запоры, диарея). У больных с сопутствующей почечной недостаточностью — жажда, снижение АД, гипорефлексия."}},{"type":"paragraph","data":{"text":"При появлении указанных симптомов следует проводить симптоматическое лечение."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Интервал между приемом Гастала и других лекарственных средств должен составлять 1-2 ч."}},{"type":"paragraph","data":{"text":"Гастал усиливает активность леводопы и налидиксовой кислоты; снижает и замедляет абсорбцию тетрациклиновых антибиотиков, ципрофлокацина и офлоксацина, салицилатов, изониазида, напроксена, препаратов железа, сердечных гпикозидов, индометацина, аминазина, фенитоина, блокаторов Н\u003csub\u003e2\u003c/sub\u003e-гистаминовых рецепторов, бета-адрепоблокаторов, дифлунизала, жирорастворимых витаминов, непрямых антикоагулянтов, барбитуратов. М- холиноблокаторы, замедляя опорожнение желудка, усиливают и удлиняют действие препарата."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Пациентам с небольшой массой тела и детям применяются меньшие дозы и менее длительно."}},{"type":"paragraph","data":{"text":"Пациентам с нарушением функции почек не рекомендуется применение Гастала более длительное и в более высоких дозах, чем рекомендовано."}},{"type":"paragraph","data":{"text":"Непрерывный прием более 2-х недель - только после консультации врача."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Применение препарата Гастал не оказывает влияния на способность к вождению автотранспорта и управлению другими механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Круглые таблетки от белого до кремового цвета с гладкой поверхностью и фаской."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить при температуре не выше 25°С."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"Срок годности – 3 года. Не применять по истечении, срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Препарат разрешен к применению в качестве средства безрецептурного отпуска."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/firm/1286\"\u003ePLIVA HRVATSKA \u003c/a\u003e(Хорватия) "}}]}],"source":null},"description_toggle":false,"short_description":"Гастал - комбинированный антацидный препарат для приема внутрь. Снижает повышенную кислотность желудочного сока до физиологического уровня и устраняет диспепсические расстройства за счет нейтрализации избытка соляной кислоты в желудке. Входящие в состав Гастала гидроксид магния и гидроксид алюминия обеспечивают быструю и длительную нейтрализацию, обусловливающую антацидный эффект. Антацидное действие препарата проявляется сразу после приема таблеток Гастала и продолжается около 2 ч. 1 таблетка Гастала нейтрализует около 21.5 ммоль соляной кислоты. Гастал ингибирует действие пепсина, лизолецитина и желчных кислот, таким образом, также устраняя расстройства функции желудка. Гастал помимо антацидного эффекта активирует защитные и регенеративные механизмы в слизистой оболочке желудка. Цитопротекторное действие, обусловленное ионами алюминия, включает стимулирование секреции слизи и гидрокарбоната натрия в желудке, накопление эпидермального фактора роста в очаге повреждения, увеличение концентрации фосфолипидов в желудке и другие механизмы. Гастал не оказывает системного действия у пациентов с нормальной функцией почек. После взаимодействия с соляной кислотой желудочного сока, гидроксид алюминия реагирует с фосфатами и карбонатами в щелочной среде кишечника и выделяется с калом в виде нерастворимых солей. 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