1 таблетка содержит: Активное вещество: пропранолола гидрохлорид 40 мг.
Показания к применению
Артериальная гипертензия. Стенокардия напряжения, нестабильная стенокардия. Синусовая тахикардия (в т.ч. при гипертиреозе), наджелудочковая тахикардия. Тахисистолическая форма мерцания предсердий. Наджелудочковая и желудочковая экстрасистолия. Эссенциальный тремор. Профилактика мигрени . Алкогольная абстиненция (ажитация и дрожание). Тревожность. Феохромоцитома (вспомогательное лечение). Диффузно-токсический зоб и тиреотоксический криз (в качестве вспомогательного средства, в т.ч. при непереносимости тиреостатических препаратов). Симпатоадреналовые кризы на фоне диэнцефального синдрома.
Противопоказания
гиперчувствительность; AV блокада 5 ст.
синоатриальная блокада; синусовая брадикардия.
Применение при беременности и в период грудного вскармливания
Применение пропранолола при беременности возможно только в том случае, когда предполагаемая польза для матери превышает потенциальный риск для плода. При необходимости применения в этот период необходимо тщательное наблюдение за состоянием плода, за 48-72 ч до родов пропранолол следует отменить. Следует иметь в виду, что возможно негативное влияние на плод: внутриутробная задержка роста, гипогликемия, брадикардия . Пропранолол выделяется с грудным молоком. При необходимости применения в период лактации следует установить врачебное наблюдение за ребенком или прекратить грудное вскармливание.
Способ применения и дозы
При приеме внутрь режим дозирования индивидуальный. Начальная доза составляет 20 мг. Разовая доза - 40-80 мг, частота приема - 2-3 раза/сут. Максимальные дозы: 320 мг/сут.
Побочное действие
Со стороны ЦНС и периферической нервной системыПовышенная утомляемость, слабость, головокружение, головная боль, сонливость или бессонница, яркие сновидения, депрессия, спутанность сознания , галлюцинации, тремор, нервозность, беспокойство. Со стороны органов чувствУменьшение секреции слезной жидкости (сухость и болезненность глаз). Со стороны сердечно-сосудистой системыСинусовая брадикардия , AV блокада (вплоть до развития полной поперечной блокады и остановки сердца), аритмии , развитие (усугубление) хронической сердечной недостаточности , снижение АД, ортостатическая гипотензия, проявление ангиоспазма (усиление нарушения периферического кровообращения, похолодание нижних конечностей, синдром Рейно), боль в груди. Со стороны пищеварительной системыТошнота, рвота , дискомфорт в эпигастральной области, запор или диарея, нарушения функции печени (темная моча, желтушность склер или кожи, холестаз), изменения вкуса, повышение активности печеночных трансаминаз, ЛДГ. Со стороны дыхательной системыЗаложенность носа, бронхоспазм. Со стороны эндокринной системыИзменение концентрации глюкозы крови (гипо- или гипергликемия). Со стороны системы кроветворенияТромбоцитопения (необычные кровотечения и кровоизлияния), лейкопения. Дерматологические реакцииУсиление потоотделения, псориазоподобные кожные реакции, обострение симптомов псориаза. Аллергические реакцииЗуд, кожная сыпь, крапивница. ПрочиеБоль в спине, артралгии, снижение потенции, синдром отмены (усиление приступов стенокардии, инфаркт миокарда, повышение АД ).
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