• Когнитивные нарушения при органических поражениях головного мозга и невротических расстройствах;
• в составе комплексной терапии цереброваскулярной недостаточности, вызванной атеросклеротическими изменениями сосудов головного мозга; сенильной деменции (начальной формы), резидуальных органических поражений мозга у лиц зрелого возраста и пожилых;
Таблетки белого цвета плоскоцилиндрической формы с фаской и риской для дозировки 500 мг, сфаҫкой и крестообразной риской для дозировки 250 мг.
Фармакотерапевтическая группа
Ноотропное средство.
Фармакологические свойства
Фармакодинамика Спектр действия связан с наличием в структуре гамма-аминомаслянной кислоты. Механизм действия обусловлен прямым влиянием пантокальцина на ГАМКБ - рецептор-канальный комплекс. Обладает нейрометаболическими, нейропротекторными и нейротрофическими свойствами. Повышает устойчивость мозга к гипоксии и воздействию токсических веществ, Стимулирует анаболические процессы в нейронах. Обладает противосудорожным действием, уменьшает моторную возбудимость с одновременным упорядочением поведения. Повышает умственную и физическую работоспособность. Способствует нормализации содержания гамма-аминомасляной кислоты при хронической алкогольной Интоксикации и последующей отмене этанола. Проявляет анальгезирующее действие. Способен ингибировать реакции ацетилирования, участвующие в механизмах инактивации новокаина и сульфаниламидов, благодаря чему достигается пролонгирование действия Последних. Вызывает торможение патологически повышенного пузырного рефлекса и тонуса детрузора. Фармакокинетика Быстро всасывается в желудочно-кишечном тракте. Время достижения максимальной концентрации в плазме крови составляет 1 ч. Наибольшие концентрации создаются в печени, почках, в стенке желудка, коже. Проникает через гематоэнцефалический барьер. Не метаболизируется. Выводится в неизмененном виде в течение 48 ч (67,5% от принятой дозы - смочой, 28,5% - с калом).
Показания к применению
• Когнитивные нарушения при органических поражениях головного мозга и невротических расстройствах;
• в составе комплексной терапии цереброваскулярной недостаточности, вызванной атеросклеротическими изменениями сосудов головного мозга; сенильной деменции (начальной формы), резидуальных органических поражений мозга у лиц зрелого возраста и пожилых;
• церебральная органическая недостаточность у больных шизофренией (в комбинации с нейролептиками, антидепрессантами);
• экстрапирамидные гиперкинезы у больных с наследственными заболеваниями нервной системы (хорея ГенТИНГТона, гепатоцеребральная дистрофия, болезнь Паркинсона и др.);
• последствия перенесенных нейроинфекций и черепно-мозговых травм (в составе Комплексной терапии);
• для коррекции побочного действия нейролептиков и с профилактической целью одновременно как "терапия прикрытия"; экстрапирамидный нейролептический синдром (гиперкинетический иакинетический);
• эпилепсия с замедлением психических процессов (в комбинации с противосудорожными препаратами).
• психоэмоциональные перегрузки, снижение умственной и физической работоспособности; для улучшения концентрации Внимания и запоминания;
• детям при умственной отсталости (задержка психического, речевого, моторного развития или их сочетания); детском церебральном параличе; заикании (преимущественно клоническая форма); эпилепсии (в составе комбинированной терапии с противосудорожными препаратами, особенно при полиморфных приступах и малых эпилептических припадках).
Внутрь, через 15-30 минут после еды. Разовая доза для взрослых составляет 0,5-1 г, для детей - 0,25-0,5 г, суточная доза для взрослых - 1,5-3 г, для детей - 0,75-3 г. Длительность курса лечения - от 1 до 4 месяцев, в отдельных случаях до 6 месяцев. Через 3-6 месяцев возможно проведение повторного курса лечения. Детям при умственной недостаточности: по 0,5 г 4-6 раз в день, ежедневно в течение 3 месяцев, при задержке речевого развития - по 0,5г 3-4 раза в день в течение 2-3 месяцев. При нейролептическом синдроме (в качестве корректора побочного действия нейролептических средств): взрослым по 0,5-1 г 3 раза в день, детям - 0,25-0,5г 3-4 раза в день. Длительность курса лечения -1-3 месяца. При эпилепсии: детям по 0,25-0,5 г 3-4 раза в день, взрослым по 0,5-1 г3-4 раза в день ежедневно в течение длительного времени (до 6 месяцев). При гиперкинезах (тиках): детям по 0,25-0,5 г 3-6 раз в день ежедневно в течение 1-4 месяцев, взрослым - по 1,5-3 гв день ежедневно в течение 1-5 месяцев. При расстройствах мочеиспускания: взрослым по 0,5-1 г 2-3 раза в день (суточная доза 2-3 г), детям - по 0,25-0,5 г (суточная доза 25-50 мг/кг). Длительность курса лечения - от 2недель до 3 месяцев (зависит от выраженности расстройств и терапевтического эффекта). При последствиях нейроинфекцийичерепно-мозговых травм: По 0,25 г 3-4 раза в день. Для восстановления работоспособности при повышенных нагрузках и астенических состояниях: по 0,25 г3 раза в день. Данная лекарственная форма не рекомендована детям до 3-х лет.
Взаимодействие с другими лекарственными средствами
Пролонгирует действие барбитуратов; усиливает эффекты препаратов, стимулирующих центральную нервную систему, противосудорожных лекарственных средств, действие местных анестетиков (прокаина). Предотвращает побочное действие фенобарбитала, карбамазепина, антипсихотических средств (нейролептиков). Действие гопантеновой кислоты усиливается в сочетании С ГЛИЦИном, КСИДифоном.
Форма выпуска
Таблетки по 250 мг или 500 мг. По 10 таблеток в контурной ячейковой упаковке или в контурной ячейковой упаковке с перфорацией из пленки поливинилхлоридной и фольги алюминиевой печатной лакированной. По 50 таблеток помещают в банки полимерные в комплекте с крышками. Каждую банку, 5 контурных упаковок вместе с инструкцией по применению помещают в пачку из картона.
Условия хранения
В защищенном от света месте при температуре не выше 25°С. Хранить в недоступном для детей месте.
Срок годности
4 года. Не использовать после истечения срока годности.
Условия отпуска
По рецепту.
Производитель
ПАО «Валента Фарм».
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Обладает противосудорожным действием, уменьшает моторную возбудимость с одновременным упорядочением поведения. Повышает умственную и физическую работоспособность. Способствует нормализации содержания гамма-аминомасляной кислоты при хронической алкогольной Интоксикации и последующей отмене этанола. Проявляет анальгезирующее действие. Способен ингибировать реакции ацетилирования, участвующие в механизмах инактивации новокаина и сульфаниламидов, благодаря чему достигается пролонгирование действия Последних. Вызывает торможение патологически повышенного пузырного рефлекса и тонуса детрузора. Фармакокинетика Быстро всасывается в желудочно-кишечном тракте. Время достижения максимальной концентрации в плазме крови составляет 1 ч. Наибольшие концентрации создаются в печени, почках, в стенке желудка, коже. Проникает через гематоэнцефалический барьер. Не метаболизируется. Выводится в неизмененном виде в течение 48 ч (67,5% от принятой дозы - смочой, 28,5% - с калом). "}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"• Когнитивные нарушения при органических поражениях головного мозга и невротических расстройствах; "}},{"type":"paragraph","data":{"text":"• в составе комплексной терапии цереброваскулярной недостаточности, вызванной атеросклеротическими изменениями сосудов головного мозга; сенильной деменции (начальной формы), резидуальных органических поражений мозга у лиц зрелого возраста и пожилых; "}},{"type":"paragraph","data":{"text":"• церебральная органическая недостаточность у больных шизофренией (в комбинации с нейролептиками, антидепрессантами); "}},{"type":"paragraph","data":{"text":"• экстрапирамидные гиперкинезы у больных с наследственными заболеваниями нервной системы (хорея ГенТИНГТона, гепатоцеребральная дистрофия, болезнь Паркинсона и др.); "}},{"type":"paragraph","data":{"text":"• последствия перенесенных нейроинфекций и черепно-мозговых травм (в составе Комплексной терапии); "}},{"type":"paragraph","data":{"text":"• для коррекции побочного действия нейролептиков и с профилактической целью одновременно как \"терапия прикрытия\"; экстрапирамидный нейролептический синдром (гиперкинетический иакинетический); "}},{"type":"paragraph","data":{"text":"• эпилепсия с замедлением психических процессов (в комбинации с противосудорожными препаратами). "}},{"type":"paragraph","data":{"text":"• психоэмоциональные перегрузки, снижение умственной и физической работоспособности; для улучшения концентрации Внимания и запоминания; "}},{"type":"paragraph","data":{"text":"• расстройства мочеиспускания: энурез, дневное недержание мочи, поллакиурия, императивные позывы; "}},{"type":"paragraph","data":{"text":"• детям при умственной отсталости (задержка психического, речевого, моторного развития или их сочетания); детском церебральном параличе; заикании (преимущественно клоническая форма); эпилепсии (в составе комбинированной терапии с противосудорожными препаратами, особенно при полиморфных приступах и малых эпилептических припадках). "}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Гиперчувствительность; острая почечная недостаточность; беременность (1 триместр)."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь, через 15-30 минут после еды. Разовая доза для взрослых составляет 0,5-1 г, для детей - 0,25-0,5 г, суточная доза для взрослых - 1,5-3 г, для детей - 0,75-3 г. Длительность курса лечения - от 1 до 4 месяцев, в отдельных случаях до 6 месяцев. Через 3-6 месяцев возможно проведение повторного курса лечения. Детям при умственной недостаточности: по 0,5 г 4-6 раз в день, ежедневно в течение 3 месяцев, при задержке речевого развития - по 0,5г 3-4 раза в день в течение 2-3 месяцев. При нейролептическом синдроме (в качестве корректора побочного действия нейролептических средств): взрослым по 0,5-1 г 3 раза в день, детям - 0,25-0,5г 3-4 раза в день. Длительность курса лечения -1-3 месяца. При эпилепсии: детям по 0,25-0,5 г 3-4 раза в день, взрослым по 0,5-1 г3-4 раза в день ежедневно в течение длительного времени (до 6 месяцев). При гиперкинезах (тиках): детям по 0,25-0,5 г 3-6 раз в день ежедневно в течение 1-4 месяцев, взрослым - по 1,5-3 гв день ежедневно в течение 1-5 месяцев. При расстройствах мочеиспускания: взрослым по 0,5-1 г 2-3 раза в день (суточная доза 2-3 г), детям - по 0,25-0,5 г (суточная доза 25-50 мг/кг). Длительность курса лечения - от 2недель до 3 месяцев (зависит от выраженности расстройств и терапевтического эффекта). При последствиях нейроинфекцийичерепно-мозговых травм: По 0,25 г 3-4 раза в день. Для восстановления работоспособности при повышенных нагрузках и астенических состояниях: по 0,25 г3 раза в день. Данная лекарственная форма не рекомендована детям до 3-х лет. "}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Возможны аллергические реакции: ринит, конъюнктивит, кожные высыпания."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Пролонгирует действие барбитуратов; усиливает эффекты препаратов, стимулирующих центральную нервную систему, противосудорожных лекарственных средств, действие местных анестетиков (прокаина). Предотвращает побочное действие фенобарбитала, карбамазепина, антипсихотических средств (нейролептиков). Действие гопантеновой кислоты усиливается в сочетании С ГЛИЦИном, КСИДифоном."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки по 250 мг или 500 мг. По 10 таблеток в контурной ячейковой упаковке или в контурной ячейковой упаковке с перфорацией из пленки поливинилхлоридной и фольги алюминиевой печатной лакированной. По 50 таблеток помещают в банки полимерные в комплекте с крышками. Каждую банку, 5 контурных упаковок вместе с инструкцией по применению помещают в пачку из картона."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В защищенном от света месте при температуре не выше 25°С. Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"4 года. Не использовать после истечения срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту."}}]},{"id":17,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ПАО «Валента Фарм»."}}]}],"source":null},"description_toggle":false,"short_description":"Фармакодинамика Спектр действия связан с наличием в структуре гамма-аминомаслянной кислоты. 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Время достижения максимальной концентрации в плазме крови составляет 1 ч. Наибольшие концентрации создаются в печени, почках, в стенке желудка, коже. Проникает через гематоэнцефалический барьер. Не метаболизируется. 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