Баралгин М Таблетки, коробка, 20 шт, 500 мг, для приема внутрь

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Если состояние не улучшилось после 5 дней лечения при болевом синдроме и после 3 дней при лечении лихорадочного синдрома или ухудшилось на фоне приема препарата, пациенту следует обратиться к врачу."}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Агранулоцитоз, лейкопения, тромбоцитопения, резкое падение АД, преходящие нарушения функции почек (олигурия или анурия, протеинурия), интерстициальный нефрит, аллергические и иммунопатологические реакции (уртикарные высыпания на коже, конъюнктиве, слизистых оболочках в области носоглотки; синдром Стивенса-Джонсона, синдром Лайелла, анафилактический шок)"}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"В случае передозировки необходимо проконсультироваться с врачом. Возможно появление следующих симптомов: тошнота, рвота, боли в желудке, олигурия, гипотермия, снижение артериального давления, тахикардия, одышка, шум в ушах, сонливость, бред, нарушение сознания, острый агранулоцитоз, геморрагический синдром, острая почечная или печеночная недостаточность, судороги, паралич дыхательной мускулатуры. Лечение: вызвать рвоту, промывание желудка через зонд; солевые слабительные, активированный уголь; проведение форсированного диуреза, гемодиализ; при развитии судорожного синдрома - внутривенное введение диазепама и быстродействующих барбитуратов."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eС циклоспорином\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Метамизол натрия может снижать концентрацию циклоспорина в сыворотке крови, поэтому при их совместном применении следует контролировать концентрации циклоспорина."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС другими ненаркотическими анальгезирующими средствами \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Одновременное применение метамизола натрия с другими ненаркотическими анальгезирующими средствами может привести к взаимному усилению токсических эффектов."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС трициклическими антидепрессантами, пероральными контрацептивами, аллопуринолом\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Трициклические антидепрессанты, пероральные контрацептивы, аллопуринол нарушают метаболизм метамизола натрия в печени и повышают его токсичность."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС барбитуратами, фенилбутазоном и другими индукторами микросомальных ферментов печени\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Барбитураты, фенилбутазон и другие индукторы микросомальных ферментов печени ослабляют действие метамизола натрия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС седативными средствами и транквилизаторами \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Седативные средства и транквилизаторы усиливают обезболивающее действие метамизола натрия. При одновременном применении метамизола натрия и хлорпромазина может развиться тяжелая гипотермия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС лекарственными средствами, имеющими высокую связь с белками плазмы (пероральные гипогликемические средства, непрямые антикоагулянты, ГКС и индометацин)\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Метамизол натрия, вытесняя из связи с белками плазмы пероральные гипогликемические средства, непрямые антикоагулянты, ГКС и индометацин, усиливает их действие."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС миелотоксичными лекарственными средствами\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Миелотоксичные лекарственные средства усиливают проявление гематотоксичности метамизола натрия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС метотрексатом\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Добавление метамизола натрия к лечению метотрексатом может усиливать гематотоксическое действие метотрексата, особенно у пациентов пожилого возраста. Поэтому следует избегать совместного применения этих лекарственных средств."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС тиамазолом и сарколизином\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Тиамазол и сарколизин повышают риск развития лейкопении."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС кодеином, блокаторами гистаминовых Н\u003csub\u003e2\u003c/sub\u003e-рецепторов и пропранололом\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Кодеин, блокаторы гистаминовых Н\u003csub\u003e2\u003c/sub\u003e-рецепторов и пропранолол усиливают эффекты метамизола натрия. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eС рентгеноконтрастными веществами, коллоидными кровезаменителями и пенициллином\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Рентгеноконтрастные вещества, коллоидные кровезаменители и пенициллин не должны применяться во время лечения метамизолом натрия (повышенный риск развития анафилактических/анафилактоидных реакций)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eС ацетилсалициловой кислотой\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"При совместном применении метамизол натрия может уменьшать влияние ацетилсалициловой кислоты на агрегацию тромбоцитов. Поэтому данную комбинацию следует применять с осторожностью при лечении пациентов, принимающих низкие дозы ацетилсалициловой кислоты для кардиопротекции (профилактики тромбообразования). "}},{"type":"paragraph","data":{"text":"\u003ci\u003eС бупропионом\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Метамизол натрия может снижать концентрацию бупропиона в крови, что следует принимать во внимание при одновременном применении метамизола натрия и бупропиона."}}]},{"id":9,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Выведение с мочой одного из продуктов биотрансформации может вызывать красное окрашивание мочи (клинического значения не имеет и исчезает после отмены)"}}]},{"name":"Условия хранения","slug":"storage","id":18,"body":[{"type":"paragraph","data":{"text":"Препарат следует хранить в недоступном для детей, защищенном от света месте при температуре от 8°С до 25°С."}}]},{"name":"Срок годности","slug":"expiry_date","id":19,"body":[{"type":"paragraph","data":{"text":"Срок годности - 4 года. Не использовать препарат по истечении срока годности, указанного на упаковке."}}]},{"name":"Условия отпуска","slug":"release_condition","id":20,"body":[{"type":"paragraph","data":{"text":"Препарат отпускается без рецепта."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Противовоспалительное, жаропонижающее, анальгезирующее, спазмолитическое. Блокирует циклооксигеназу и снижает синтез ПГ. Анальгезирующее ненаркотическое средство группы пиразолонов, обладает обезболивающим, жаропонижающим и спазмолитическим действием. Его механизм действия окончательно не установлен. Имеющиеся данные позволяют полагать, что метамизол и его основной метаболит (4N-метиламиноантипирин [4-МАА]) обладают центральным и периферическим механизмом действия. В дозах, превышающих терапевтические, может достигаться противовоспалительный эффект, возможно за счет подавления синтеза простагландинов.","substance":[{"id":568,"title":"Метамизол натрия","title_latin":"Metamizolum natrium","slug":"metamizol_natriya_568"}],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":true,"comments":null,"image_alt":"Баралгин М - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/12816/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/12816/share_default/"}},"diseases":[{"id":"900","title":"Желчнокаменная болезнь [холелитиаз] (в т.ч. печеночная колика)","slug":"900-zhelchnokamennaya_bolezn_holelitiaz_v_tch_pechenochnaya_kolika"},{"id":"1057","title":"Миалгия","slug":"1057-mialgiya"},{"id":"1058","title":"Невралгия и неврит неуточненные","slug":"1058-nevralgiya_i_nevrit_neutochnennye"},{"id":"1096","title":"Почечная колика 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