Комбинированный препарат Витапрост Плюс обладает антимикробн... Инструкция
Показания к применению
Острый и хронический бактериальный простатит, вызванный чувствительными микроорганизмами, в том числе сопровождающийся воспалительными заболеваниями мочеполового тракта.
Состояния до и после оперативного вмешательства на предстательной железе.
Противопоказания
Повышенная чувствительность к компонентам препарата.
Возраст до 18 лет (период формирования и роста скелета).
действующие вещества: простаты экстракт — 100 мг (в пересчете на водорастворимые пептиды — 20 мг); ломефлоксацина гидрохлорид — 400мг;
вспомогательные вещества: жир твердый (Витепсол, марки H 15, W 35, Суппосир, марки NA 15, NAS 50) — до получения суппозитория массой 2,25 г.
Описание
Суппозитории торпедообразной формы от белого или почти белого до светло-кремового с сероватым оттенком цвета. Допускается появление белого налета на поверхности суппозитория и наличие на срезе воздушного стержня и воронкообразного углубления.
Фармакотерапевтическая группа
Противомикробное средство - фторхинолон.
Фармакологические свойства
Комбинированный препарат Витапрост Плюс обладает антимикробными и противовоспалительными свойствами.
Показания к применению
Острый и хронический бактериальный простатит, вызванный чувствительными микроорганизмами, в том числе сопровождающийся воспалительными заболеваниями мочеполового тракта.
Состояния до и после оперативного вмешательства на предстательной железе.
Противопоказания
Повышенная чувствительность к компонентам препарата.
Возраст до 18 лет (период формирования и роста скелета).
С осторожностью
Церебральный атеросклероз, эпилепсия и другие заболевания центральной нервной системы с эпилептическим синдромом, электролитный дисбаланс (например, при гипокалиемии, гипомагниемии), одновременный прием антиаритмических лекарственных средств IА класса (хинидин, прокаинамид) и III класса (амиодарон, соталол), синдром удлинения интервала Q-T, другие заболевания сердечно-сосудистой системы (сердечная недостаточность, инфаркт миокарда, брадикардия), почечная недостаточность, пожилой возраст, поражение сухожилий при ранее проводившемся лечении фторхинолонами.
Способ применения и дозы
Ректально. По 1 суппозиторию 1 раз в день после клизмы или самостоятельного опорожнения кишечника. Перед применением суппозиторий следует извлечь из контурной ячейковой упаковки. После введения препарата Витапрост Плюс желательно в течение 30-40 минут находиться в постели. Курс лечения продолжается до исчезновения возбудителя в секрете простаты и составляет от 10 до 30 дней (продолжительность лечения определяется врачом индивидуально для каждого пациента).
При необходимости возможно проведение повторных курсов. Если после лечения улучшения не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом.
Побочное действие
Побочные действия препарата Витапрост Плюс, за исключением аллергических реакций, связаны с наличием в его составе антибиотика ломефлоксацин.
Со стороны пищеварительной системы: тошнота, рвота, сухость слизистой оболочки полости рта, гастралгия, боли в животе, диарея или запор, метеоризм, псевдомембранозный колит, дисфагия, изменение цвета языка, снижение аппетита или булимия, извращение вкуса, дисбактериоз, повышение активности «печеночных» трансаминаз.
Со стороны психики: Нарушения внимания, дезориентация, ажитация, нервозность, нарушение памяти, делирий.
Со стороны мочеполовой системы: гломерулонефрит, дизурия, полиурия, анурия, альбуминурия, уретральные кровотечения, кристаллурия, гематурия, задержка мочи, отеки; орхит, эпидидимит.
Со стороны обмена веществ: гипогликемия, гипергликемия, дисгликемия, подагра.
Тяжелая гипогликемия, вплоть до развития гипогликемической комы, особенно у пожилых пациентов, пациентов с сахарным диабетом, принимающих пероральные гипогликемические препараты или инсулин.
Со стороны опорно-двигательного аппарата: артралгия, васкулит, судороги икроножных мышц, боли в спине и груди, разрыв сухожилия.
Со стороны органов кроветворения и системы гемостаза: кровотечения из органов желудочно-кишечного тракта, тромбоцитопения, пурпура, повышение фибринолиза, носовое кровотечение, лимфоаденопатия.
Со стороны дыхательной системы: диспноэ, бронхоспазм, кашель, гиперсекреция мокроты, гриппоподобные симптомы.
Со стороны органов чувств: нарушение зрения, боль и шум в ушах, боль в глазах.
Со стороны сердечно-сосудистой системы: снижение артериального давления, тахикардия, брадикардия, экстрасистолия, аритмии, прогрессирование сердечной недостаточности и стенокардии, тромбоэмболия легочной артерии, кардиомиопатия, флебит, удлинение интервала QT, желудочковая аритмия типа «пируэт».
Если любые из указанных выше побочных эффектов усугубляются или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.
Передозировка
О случаях передозировки препарата Витапрост Плюс не сообщалось.
Сведения о передозировке ломефлоксацина очень ограничены. Проводится симптоматическая терапия. Гемо- и перитонеальный диализ при передозировке малоэффективны.
Взаимодействие с другими лекарственными средствами
Повышает активность пероральных антикоагулянтов и увеличивает токсичность нестероидных противовоспалительных препаратов.
Совместное применение с антиаритмическими препаратами I А класса (хинидин, прокаинамид) и III класса (амиодарон, соталол) может вызывать удлинение интервала Q-T.
Отсутствует перекрестная устойчивость с пенициллинами, цефалоспоринами, аминогликозидами, ко-тримоксазолом, метронидазолом.
Препарат может применяться в комплексной терапии.
Особые указания
Особые указания при применении препарата Витапрост Плюс связаны с наличием в его составе антибиотика ломефлоксацин, относящегося к группе фторхинолонов.
В период лечения препаратом Витапрост Плюс следует ограничить одновременное применение противомикробных средств — фторхинолонов во избежание развития передозировки и увеличения частоты побочных эффектов.
При циррозе печени не требуется коррекции режима дозирования (при условии нормальной функции почек).
В период лечения следует избегать длительного воздействия солнечного света и использования искусственного ультрафиолетового освещения. При первых признаках фотосенсибилизации (повышение чувствительности кожи, ожог, гиперемия, отек, появление волдырей, сыпи, зуда, дерматита), гиперчувствительности, проявлениях нейротоксичности (возбуждение, судороги, тремор, светобоязнь, спутанность сознания, токсические психозы, галлюцинации) терапию необходимо прекратить.
Применяют только для лечения взрослых мужчин; не применяют у женщин и детей.
Лечение хронического простатита должно быть комплексным, предполагающим наряду с назначением препарата Витапрост Плюс применение других групп лекарственных препаратов и немедикаментозных методов лечения.
До начала лечения хронического простатита и, при необходимости, в процессе лечения рекомендуется проводить анализ секрета предстательной железы.
В период лечения препаратом Витапрост Плюс имеется потенциальный риск развития гипогликемии, вплоть до развития гипогликемической комы, что чаще встречается у пожилых людей и пациентов с сахарным диабетом, которые принимают пероральные гипогликемические препараты или инсулин. В связи с этим следует тщательно следить за концентрацией глюкозы в плазме крови у этих пациентов.
При первых признаках развития гипогликемии (спутанность сознания, головокружение, «волчий» аппетит, головная боль, нервозность, ощущение сердцебиения или учащение пульса, бледность кожных покровов, испарина, дрожь, слабость) терапию необходимо прекратить.
В период лечения препаратом Витапрост Плюс имеется риск развития психических побочных реакций, которые могут появиться даже после однократной дозы.
Следует немедленно прекратить лечение препаратом Витапрост Плюс, если пациент сообщает о любых побочных эффектах со стороны центральной нервной системы, включая нарушения психики, или снижении концентрации глюкозы, и немедленно начать терапию другим антибиотиком, отличным от фторхинолонов, если это возможно.
В эпидемиологических исследованиях сообщалось о повышенном риске развития аневризмы и расслоения аорты после применения фторхинолонов, особенно у пожилых пациентов.
У пациентов с аневризмой в анамнезе, либо имеющих аневризму и / или расслоение аорты, а также другие факторы риска или состояния, предрасполагающие к развитию аневризмы и расслоения аорты (например, синдром Марфана, синдром Элерса-Данло сосудистого типа, артериит Такаясу, гигантоклеточный артериит, болезнь Бехчета, артериальная гипертензия, атеросклероз), фторхинолоны следует применять только после тщательной оценки соотношения польза-риск и рассмотрения других возможных вариантов терапии.
В случае появления внезапной боли в животе, груди или спине пациентам следует немедленно обратиться к врачу в отделение неотложной помощи.
Влияние на способность управлять автомобилем и движущимися механизмами
В период лечения необходимо соблюдать осторожность при вождении автотранспорта и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций.
Форма выпуска
Суппозитории ректальные 400мг+20 мг.
5 суппозиториев в контурную ячейковую упаковку из пленки поливинилхлоридной ламинированной полиэтиленом
Одну или две контурные ячейковые упаковки вместе с инструкцией по медицинскому применению лекарственного препарата в пачку из картона
Условия хранения
При температуре не выше 25°С.
Хранить в недоступном для детей месте.
Срок годности
2 года. Не использовать препарат после истечения срока годности.
Для описания товара использована информация от партнера 36.6
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белого до светло-кремового с сероватым оттенком цвета. Допускается появление белого налета на поверхности суппозитория и наличие на срезе воздушного стержня и воронкообразного углубления."}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"Противомикробное средство - фторхинолон."}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":" Комбинированный препарат Витапрост Плюс обладает антимикробными и противовоспалительными свойствами. "}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Острый и хронический бактериальный простатит, вызванный чувствительными микроорганизмами, в том числе сопровождающийся воспалительными заболеваниями мочеполового тракта."}},{"type":"paragraph","data":{"text":"Состояния до и после оперативного вмешательства на предстательной железе."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к компонентам препарата."}},{"type":"paragraph","data":{"text":"Возраст до 18 лет (период формирования и роста скелета)."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Церебральный атеросклероз, эпилепсия и другие заболевания центральной нервной системы с эпилептическим синдромом, электролитный дисбаланс (например, при гипокалиемии, гипомагниемии), одновременный прием антиаритмических лекарственных средств IА класса (хинидин, прокаинамид) и III класса (амиодарон, соталол), синдром удлинения интервала Q-T, другие заболевания сердечно-сосудистой системы (сердечная недостаточность, инфаркт миокарда, брадикардия), почечная недостаточность, пожилой возраст, поражение сухожилий при ранее проводившемся лечении фторхинолонами."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Ректально. По 1 суппозиторию 1 раз в день после клизмы или самостоятельного опорожнения кишечника. Перед применением суппозиторий следует извлечь из контурной ячейковой упаковки. После введения препарата Витапрост Плюс желательно в течение 30-40 минут находиться в постели. Курс лечения продолжается до исчезновения возбудителя в секрете простаты и составляет от 10 до 30 дней (продолжительность лечения определяется врачом индивидуально для каждого пациента)."}},{"type":"paragraph","data":{"text":"\u003cb\u003eПри необходимости возможно проведение повторных курсов. Если после лечения улучшения не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом.\u003c/b\u003e"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Побочные действия препарата Витапрост Плюс, за исключением аллергических реакций, связаны с наличием в его составе антибиотика ломефлоксацин."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны пищеварительной системы:\u003c/i\u003e тошнота, рвота, сухость слизистой оболочки полости рта, гастралгия, боли в животе, диарея или запор, метеоризм, псевдомембранозный колит, дисфагия, изменение цвета языка, снижение аппетита или булимия, извращение вкуса, дисбактериоз, повышение активности «печеночных» трансаминаз."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны нервной системы: \u003c/i\u003eповышенная утомляемость, недомогание, астения, головная боль, головокружение, бессонница, галлюцинации, судороги, гиперкинез, тремор, парестезии, нервозность, тревожность, депрессия, возбуждение, обморок."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны психики:\u003c/i\u003e Нарушения внимания, дезориентация, ажитация, нервозность, нарушение памяти, делирий."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны мочеполовой системы:\u003c/i\u003e гломерулонефрит, дизурия, полиурия, анурия, альбуминурия, уретральные кровотечения, кристаллурия, гематурия, задержка мочи, отеки; орхит, эпидидимит."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны обмена веществ:\u003c/i\u003e гипогликемия, гипергликемия, дисгликемия, подагра."}},{"type":"paragraph","data":{"text":"Тяжелая гипогликемия, вплоть до развития гипогликемической комы, особенно у пожилых пациентов, пациентов с сахарным диабетом, принимающих пероральные гипогликемические препараты или инсулин."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны опорно-двигательного аппарата:\u003c/i\u003e артралгия, васкулит, судороги икроножных мышц, боли в спине и груди, разрыв сухожилия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны органов кроветворения и системы гемостаза: \u003c/i\u003eкровотечения из органов желудочно-кишечного тракта, тромбоцитопения, пурпура, повышение фибринолиза, носовое кровотечение, лимфоаденопатия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны дыхательной системы:\u003c/i\u003e диспноэ, бронхоспазм, кашель, гиперсекреция мокроты, гриппоподобные симптомы."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны органов чувств: \u003c/i\u003eнарушение зрения, боль и шум в ушах, боль в глазах."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны сердечно-сосудистой системы:\u003c/i\u003e снижение артериального давления, тахикардия, брадикардия, экстрасистолия, аритмии, прогрессирование сердечной недостаточности и стенокардии, тромбоэмболия легочной артерии, кардиомиопатия, флебит, удлинение интервала QT, желудочковая аритмия типа «пируэт»."}},{"type":"paragraph","data":{"text":"\u003ci\u003eАллергические реакции:\u003c/i\u003e кожный зуд, крапивница, фотосенсибилизация, злокачественная экссудативная эритема (синдром Стивенса-Джонсона)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПрочие:\u003c/i\u003e усиление потоотделения, озноб, жажда, суперинфекция."}},{"type":"paragraph","data":{"text":"\u003ci\u003e\u003cb\u003eЕсли любые из указанных выше побочных эффектов усугубляются или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.\u003c/b\u003e\u003c/i\u003e"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"О случаях передозировки препарата Витапрост Плюс не сообщалось."}},{"type":"paragraph","data":{"text":"Сведения о передозировке ломефлоксацина очень ограничены. Проводится симптоматическая терапия. Гемо- и перитонеальный диализ при передозировке малоэффективны."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Повышает активность пероральных антикоагулянтов и увеличивает токсичность нестероидных противовоспалительных препаратов."}},{"type":"paragraph","data":{"text":"Препараты, блокирующие канальцевую секрецию, замедляют выведение ломефлоксацина."}},{"type":"paragraph","data":{"text":"Совместное применение с антиаритмическими препаратами I А класса (хинидин, прокаинамид) и III класса (амиодарон, соталол) может вызывать удлинение интервала Q-T."}},{"type":"paragraph","data":{"text":"Отсутствует перекрестная устойчивость с пенициллинами, цефалоспоринами, аминогликозидами, ко-тримоксазолом, метронидазолом."}},{"type":"paragraph","data":{"text":"Препарат может применяться в комплексной терапии."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Особые указания при применении препарата Витапрост Плюс связаны с наличием в его составе антибиотика ломефлоксацин, относящегося к группе фторхинолонов."}},{"type":"paragraph","data":{"text":"В период лечения препаратом Витапрост Плюс следует ограничить одновременное применение противомикробных средств — фторхинолонов во избежание развития передозировки и увеличения частоты побочных эффектов."}},{"type":"paragraph","data":{"text":"При циррозе печени не требуется коррекции режима дозирования (при условии нормальной функции почек)."}},{"type":"paragraph","data":{"text":"В период лечения следует избегать длительного воздействия солнечного света и использования искусственного ультрафиолетового освещения. При первых признаках фотосенсибилизации (повышение чувствительности кожи, ожог, гиперемия, отек, появление волдырей, сыпи, зуда, дерматита), гиперчувствительности, проявлениях нейротоксичности (возбуждение, судороги, тремор, светобоязнь, спутанность сознания, токсические психозы, галлюцинации) терапию необходимо прекратить."}},{"type":"paragraph","data":{"text":"Применяют только для лечения взрослых мужчин; не применяют у женщин и детей."}},{"type":"paragraph","data":{"text":"Лечение хронического простатита должно быть комплексным, предполагающим наряду с назначением препарата Витапрост Плюс применение других групп лекарственных препаратов и немедикаментозных методов лечения."}},{"type":"paragraph","data":{"text":"До начала лечения хронического простатита и, при необходимости, в процессе лечения рекомендуется проводить анализ секрета предстательной железы."}},{"type":"paragraph","data":{"text":"В период лечения препаратом Витапрост Плюс имеется потенциальный риск развития гипогликемии, вплоть до развития гипогликемической комы, что чаще встречается у пожилых людей и пациентов с сахарным диабетом, которые принимают пероральные гипогликемические препараты или инсулин. В связи с этим следует тщательно следить за концентрацией глюкозы в плазме крови у этих пациентов."}},{"type":"paragraph","data":{"text":"При первых признаках развития гипогликемии (спутанность сознания, головокружение, «волчий» аппетит, головная боль, нервозность, ощущение сердцебиения или учащение пульса, бледность кожных покровов, испарина, дрожь, слабость) терапию необходимо прекратить."}},{"type":"paragraph","data":{"text":"В период лечения препаратом Витапрост Плюс имеется риск развития психических побочных реакций, которые могут появиться даже после однократной дозы."}},{"type":"paragraph","data":{"text":"Следует немедленно прекратить лечение препаратом Витапрост Плюс, если пациент сообщает о любых побочных эффектах со стороны центральной нервной системы, включая нарушения психики, или снижении концентрации глюкозы, и немедленно начать терапию другим антибиотиком, отличным от фторхинолонов, если это возможно."}},{"type":"paragraph","data":{"text":"В эпидемиологических исследованиях сообщалось о повышенном риске развития аневризмы и расслоения аорты после применения фторхинолонов, особенно у пожилых пациентов."}},{"type":"paragraph","data":{"text":"У пациентов с аневризмой в анамнезе, либо имеющих аневризму и / или расслоение аорты, а также другие факторы риска или состояния, предрасполагающие к развитию аневризмы и расслоения аорты (например, синдром Марфана, синдром Элерса-Данло сосудистого типа, артериит Такаясу, гигантоклеточный артериит, болезнь Бехчета, артериальная гипертензия, атеросклероз), фторхинолоны следует применять только после тщательной оценки соотношения польза-риск и рассмотрения других возможных вариантов терапии."}},{"type":"paragraph","data":{"text":"В случае появления внезапной боли в животе, груди или спине пациентам следует немедленно обратиться к врачу в отделение неотложной помощи."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"В период лечения необходимо соблюдать осторожность при вождении автотранспорта и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Суппозитории ректальные 400мг+20 мг."}},{"type":"paragraph","data":{"text":"5 суппозиториев в контурную ячейковую упаковку из пленки поливинилхлоридной ламинированной полиэтиленом"}},{"type":"paragraph","data":{"text":"Одну или две контурные ячейковые упаковки вместе с инструкцией по медицинскому применению лекарственного препарата в пачку из картона"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре не выше 25°С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Не использовать препарат после истечения срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают по рецепту."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nАО «Нижфарм», Россия"}},{"type":"paragraph","data":{"text":"603950, г. Нижний Новгород,"}},{"type":"paragraph","data":{"text":"ул. Салганская, д. 7"}},{"type":"paragraph","data":{"text":"Тел.: (831) 278-80-88"}},{"type":"paragraph","data":{"text":"факс: (831) 430-72-28"}},{"type":"paragraph","data":{"text":"E-mail: \u003ca href=\"mailto:med@stada.ru\"\u003emed@stada.ru\u003c/a\u003e"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"\n\nАО «Нижфарм», Россия"}},{"type":"paragraph","data":{"text":"603950, г. Нижний Новгород,"}},{"type":"paragraph","data":{"text":"ул. 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