Румикоз Капсулы, 15 шт, 100 мг, для приема внутрь

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В подобных случаях может потребоваться двукратное увеличение дозы.; Онихомикозы, вызванные дерматофитами и/или дрожжами, плесневыми грибами; Пульс-терапия; Один курс пульс-терапии заключается в ежедневном приеме Румикоза по 200 мг 2 раза/сут (по 2 капс. 2 раза/сут) в течение 1 недели (таблица 2).; Для лечения грибковых поражений ногтевых пластинок кистей рекомендуется 2 курса.; Для лечения грибковых поражений ногтевых пластинок стоп рекомендуется 3 курса.; Интервал между курсами, в течение которого не нужно принимать препарат, составляет 3 недели. Клинические результаты становятся очевидны после окончания лечения, по мере отрастания ногтей.; Непрерывная терапия; При поражении ногтевых пластинок стоп с поражением или без поражения ногтевых пластинок кистей доза составляет 200 мг/сут, продолжительность лечения - 3 мес.; Выведение Румикоза из кожи и ногтевой ткани осуществляется медленнее, чем из плазмы. Таким образом, оптимальные клинические и микологические эффекты достигаются через 2-4 недели после окончания лечения при поражениях кожи и через 6-9 мес после окончания лечения заболеваний ногтей.;"}}]},{"id":7,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы: диспепсия, тошнота, рвота, снижение аппетита, боль в животе, диарея, запор, обратимое повышение активности печеночных ферментов, гепатит; очень редко - тяжелое токсическое поражение печени, в т.ч. случаи острой печеночной недостаточности с летальным исходом.; Со стороны ЦНС и периферической нервной системы: головная боль, головокружение, периферическая невропатия.; Аллергические реакции: кожная сыпь, кожный зуд, крапивница, ангионевротический отек; редко - многоформная экссудативная эритема (синдром Стивенса-Джонсона).; Дерматологические реакции: алопеция, фотосенсибилизация.; Прочие: нарушения менструального цикла, гипокалиемия, отечный синдром, застойная сердечная недостаточность и отек легких, окрашивание мочи в темный цвет, гиперкреатининемия."}}]},{"id":8,"name":"Передозировка","slug":"overdose","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Данные о случаях передозировки препарата Румикоз; отсутствуют.; Лечение: при случайной передозировке следует применять поддерживающие меры. В течение первого часа провести промывание желудка и, если это необходимо, назначить активированный уголь. Итраконазол не выводится из организма при гемодиализе. Специфического антидота не существует."}}]},{"id":9,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"При исследовании в/в лекарственной формы итраконазола отмечалось преходящее бессимптомное уменьшение фракции выброса левого желудочка, нормализовавшееся до следующей инфузии препарата.; Обнаружено, что итраконазол обладает отрицательным инотропным эффектом. Сообщалось о случаях развития сердечной недостаточности, связанных с приемом Румикоза. Поэтому препарат не назначают пациентам с хронической сердечной недостаточностью или с наличием этого заболевания в анамнезе, за исключением случаев, когда ожидаемая польза терапии значительно превосходит потенциальный риск.; Блокаторы кальциевых каналов могут оказывать отрицательный инотропный эффект, который может усиливать подобный эффект итраконазола; итраконазол способен замедлять метаболизм блокаторов кальциевых каналов. При одновременном применении итраконазола и блокаторов кальциевых каналов требуется осторожность.; У пациентов с почечной недостаточностью возможно снижение биодоступности итраконазола, в таких случаях может потребоваться коррекция дозы.; При пониженной кислотности желудка абсорбция итраконазола нарушается. Пациентам, получающим антацидные препараты (например, гидроксид алюминия), рекомендуется принимать их не ранее чем через 2 ч после приема Румикоза. Пациентам с ахлоргидрией, а также больным, принимающим блокаторы гистаминовых Н2-рецепторов или ингибиторы протоновой помпы, рекомендуется принимать итраконазол с кислыми напитками.; В очень редких случаях при применении Румикоза развивалось тяжелое токсическое поражение печени, иногда с острой печеночной недостаточностью и летальным исходом. Это наблюдалось у пациентов с уже имеющимися заболеваниями печени, а также у пациентов, получавших другие лекарственные средства, обладающие гепатотоксическим действием. Несколько таких случаев возникли в первый месяц терапии, а некоторые - в первую неделю лечения. В связи с этим рекомендуется регулярно контролировать функцию печени у пациентов, получающих Румикоз;.; Лечение следует прекратить при возникновении невропатии, которая может быть связана с приемом Румикоза.; Нет данных о перекрестной гиперчувствительности к итраконазолу и другим азоловым противогрибковым препаратам. Румикоз; следует с осторожностью назначать пациентам с гиперчувствительностью к другим азоловым противогрибковым средствам.; У пациентов с нарушенным иммунитетом (СПИД, состояние после трансплантации органов, нейтропения) может потребоваться увеличение дозы Румикоза.; Использование в педиатрии; Румикоз; не следует назначать детям, за исключением случаев, когда ожидаемая польза терапии превосходит возможный риск.; Влияние на способность к вождению автотранспорта и управлению механизмами; Влияния на способность к управлению автомобилем и работе с техникой не наблюдалось."}}]},{"id":17,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В сухом, защищенном от света месте, при температуре не выше 25 °C."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года."}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.eapteka.ru/goods/manufacturer/valenta_farma/\"\u003eВалента Фарм, Россия\u003c/a\u003e."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Синтетический противогрибковый препарат широкого спектра действия, производное триазола. 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