Рекогнан показан при некоторых заболеваниях со стороны ЦНС, а именно: Острый период ишемического инсульта. Последствия геморрагического и ишемического инсультов, особенно эффективен в восстановительном периоде. ЧМТ разной степени тяжести. Когнитивные и эмоционально-волевые нарушения при дисциркуляторной энцефалопатии.
Противопоказания
Рекогнан может быть противопоказан при некоторых состояниях: Детский возраст, в силу недостаточности данных о безопасности. Парасимпатическое преобладание в вегетативной нервной системе. Аллергия. Тяжелые формы бронхиальной астмы. Беременность и грудное вскармливание.
Ноотропный препарат. Цитиколин, являясь предшественником ключевых ультраструктурных компонентов клеточной мембраны (преимущественно фосфолипидов), обладает широким спектром действия: способствует восстановлению поврежденных мембран клеток, ингибирует действие фосфолипаз, препятствуя избыточному образованию свободных радикалов, а также предотвращая гибель клеток, воздействуя на механизмы апоптоза. В остром периоде инсульта уменьшает объем поврежденной ткани, улучшает холинергическую передачу. При черепно-мозговой травме уменьшает длительность посттравматической комы и выраженность неврологических симптомов, кроме того, способствует уменьшению продолжительности восстановительного периода. Цитиколин улучшает наблюдающиеся при гипоксии симптомы: ухудшение памяти, эмоциональную лабильность, безынициативность, трудности при выполнении повседневных действий и самообслуживании. Эффективен при лечении когнитивных, чувствительных и двигательных неврологических нарушений дегенеративной и сосудистой этиологии. При хронической ишемии головного мозга цитиколин эффективен при лечении таких расстройств, как ухудшение памяти, безынициативность, затруднения, возникающие при выполнении повседневных действий и самообслуживании. Повышает уровень внимания и сознания, а также уменьшает проявление амнезии.
Показания к применению
Рекогнан показан при некоторых заболеваниях со стороны ЦНС, а именно: Острый период ишемического инсульта. Последствия геморрагического и ишемического инсультов, особенно эффективен в восстановительном периоде. ЧМТ разной степени тяжести. Когнитивные и эмоционально-волевые нарушения при дисциркуляторной энцефалопатии.
Противопоказания
Рекогнан может быть противопоказан при некоторых состояниях: Детский возраст, в силу недостаточности данных о безопасности. Парасимпатическое преобладание в вегетативной нервной системе. Аллергия. Тяжелые формы бронхиальной астмы. Беременность и грудное вскармливание.
Применение при беременности и в период грудного вскармливания
Данных по применению цитиколина при беременности недостаточно. Назначение препарата Рекогнан возможно только в тех случаях, когда ожидаемая польза терапии для матери превосходит потенциальный риск для плода. В исследованиях на животных отрицательного влияния не выявлено. При назначении препарата Рекогнан в период лактации женщинам следует прекратить грудное вскармливание, поскольку данные о выделении цитиколина с грудным молоком у человека отсутствуют.
Способ применения и дозы
Следует строго придерживаться рекомендуемых дозировок и длительности курсов лечения для полноценного действия Рекогнана. Раствор во флаконах используется перорально во время приема пищи. Перед применением можно разводить в воде (не больше 100 мл). Показан лишь при отсутствии бульбарных нарушений у пациента! Это же применительно и к форме выпуска в пакетиках. Инхекционные формы используют внутривенно (допускается внутримышечное использование). Рекогнан разводят в любом изотоническом растворителе (чаще используется физиологический раствор). Капельное введения предпочтительней в силу лучшей переносимости. Длительное внутримышечное использование в одну и ту же анатомическую область может привести к абсцессам. Инъекционные формы чаще применяются на этапе стационарной помощи или при наличии бульбарных расстройств. Курс терапии равен 10-14 дням. Далее рекомендован переход на пероральные формы (пакетики, раствор во флаконах). Дозы зависят от конкретной ситуации. При ишемических инсультах, а также в остром периоде ЧМТ рекомендовано применять 1 грамм Рекогнана (10 мл сиропа или 1 пакетик) 2 раза в сутки. Курс лечения длительный, минимально составляет 40-45 дней. Для реабилитации, в том числе после геморрагического поражения мозга используют Рекогнан в дозе от 500 до 2000 миллиграмм. Лечение также длительное и зависит от выраженности проявлений заболевания, а также эффективности препарата.
Побочное действие
Побочные эффекты развиваются крайне редко. Чаще отмечаются реакции гиперчувствительности. При этом возможна непереносимость компонентов растворителей инъекционных форм, консерванта раствора для приема внутрь, а не аллергия на цитиколин. Редко отмечались такие нежелательные явления как головокружение, галлюцинации, тремор конечностей, скачки АД. Часто данные явления могли быть проявлениями основного заболевания.
Передозировка
С учетом низкой токсичности препарата случаи передозировки не описаны.
Особые указания
Влияние на способность к вождению автотранспорта и управлению механизмами: В период лечения пациенты должны соблюдать осторожность при выполнении потенциально опасных видов деятельности, требующих повышенного внимания и быстроты психомоторных реакций (в т.ч. управление транспортными средствами. работа с движущимися механизмами, работа диспетчера, оператора).
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