Панзинорм форте 20000 Таблетки, 30 шт, покрытые кишечно-растворимой оболочкой

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Незначительная часть пищеварительных ферментов выделяется через кишечник."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Недостаточность внешнесекреторной функции поджелудочной железы (хронический панкреатит, муковисцидоз и пр.)."}},{"type":"paragraph","data":{"text":"Хронические воспалительно-дистрофические заболевания желудка, кишечника, печени, желчного пузыря; состояния после резекции или облучения этих органов, сопровождающиеся нарушениями переваривания пищи, метеоризмом, диареей (в составе комбинированной терапии)."}},{"type":"paragraph","data":{"text":"Для улучшения переваривания пиши у пациентов с нормальной функцией желудочно-кишечного тракта в случае погрешностей в питании, при нарушениях жевательной функции (повреждение зубов и десен, в период привыкания к зубным протезам), малоподвижном образе жизни; длительной иммобилизации."}},{"type":"paragraph","data":{"text":"Подготовка к рентгенологическому и ультразвуковому исследованию органов брюшной полости."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"list","data":{"style":"ordered","items":["Повышенная чувствительность к свиному белку или другим компонентам препарата;","Острый панкреатит, обострение хронического панкреатита;","Дети до 3-х лет (для данной лекарственной формы) и дети до 15 лет, страдающие муковисцидозом."]}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"беременность."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Применение Панзинорма форте 20 000 при беременности и в период лактации (грудного вскармливания) возможно только в том случае, если ожидаемый положительный эффект терапии превосходит возможный риск, в связи с отсутствием клинических данных, подтверждающих безопасность применения ферментов поджелудочной железы у этой категории пациентов."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь, принимать во время еды. Таблетки следует принимать, не разжевывая с достаточным количеством жидкости."}},{"type":"paragraph","data":{"text":"Доза и длительность терапии определяется индивидуально в зависимости от возраста и степени недостаточности поджелудочной железы."}},{"type":"paragraph","data":{"text":"Взрослым Панзинорм форте 20 000 рекомендуют принимать (при отсутствии других предписаний) в начале лечения по 1 таблетке 3 раза в день, во время каждого основного приема пищи. Возможен прием Панзинорма форте 20 000 во время приема легкой закуски. При необходимости разовую дозу увеличивают в 2 раза. Средняя суточная доза: 1-2 таблетки 3 раза. Перед рентгенологическим и ультразвуковом исследованиях - по 2 таблетки 2-3 раза в сутки за 2-3 дня до обследования."}},{"type":"paragraph","data":{"text":"У детей препарат применяется по назначению врача. Детям в возрасте старше 3-х лет -100 тыс. ЕД/сут (в пересчете на липазу)."}},{"type":"paragraph","data":{"text":"Продолжительность лечения может варьировать от однократного приема или нескольких дней (при нарушении процесса пищеварения вследствие погрешностей в диете) до нескольких месяцев или лет (при необходимости постоянной заместительной терапии)."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Аллергические реакции: гиперемия кожи, кожная сыпь, кожный зуд, чихание, удушье, слезотечение."}},{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы (при длительном приеме в больших дозах): тошнота, рвота, боль в животе (в т.ч. кишечная колика), диарея, запор, перианальное раздражение, раздражение слизистой оболочки полости рта. При муковисцидозе в случае превышения необходимой дозы панкреатина (более 10 000 ЕД Ph. Eur. липазы на 1 кг массы тела) возможно развитие стриктур (фиброзной колонопатии) в илеоцекальном отделе и в восходящей ободочной кишке."}},{"type":"paragraph","data":{"text":"Прочие: гиперурикемия, гиперурикозурия, недостаточность фолатов."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптомы: тошнота, рвота, диарея, гиперурикозурия, гиперурикемия, перианальное раздражение, фиброзная колонопатия (при муковицидозе). Лечение: отмена препарата, гидратация, симптоматическая терапия."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"  При одновременном применении с панкреатином возможно снижение всасывания препаратов железа (клинически незначимо) и фолиевой кислоты. Рекомендуется периодически контролировать уровень фолатов и/или назначение фолиевой кислоты. Устойчивая к кислоте оболочка таблеток Панзинорм форте 20 000 растворяется в 12-перстной кишке. При низком значении рН в 12-перстной кишке панкреатин не высвобождается. Одновременное применение блокаторов Н\u003csub\u003e2\u003c/sub\u003e-гистаминовых рецепторов (циметидин), гидрокарбонатов, ингибиторов протонового насоса может привести к повышению эффективности панкреатина.  "}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Панзинорм форте 20 000 следует принимать, не разжевывая, с достаточным количеством жидкости."}},{"type":"paragraph","data":{"text":"При муковисцидозе в случае превышения необходимой дозы панкреатина (более 10 000 ЕД Ph. Eur. липазы на 1 кг массы тела) возможно развитие стриктур (фиброзной колонопатии) в илеоцекальном отделе и в восходящей ободочной кишке. Поэтому при муковисцидозе доза должна быть адекватна количеству ферментов, которое необходимо для всасывания жиров с учетом качества и количества потребляемой пищи. Капсулу гидросорбента не проглатывать!"}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"не известно об отрицательном влиянии на способность управления автомобилем и работе с другими механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nТаблетки, покрытые кишечнорастворимой оболочкой."}},{"type":"paragraph","data":{"text":"По 10, 30 или 100 таблеток в стеклянном флаконе янтарного цвета (III типа) с капсулой гидросорбента, закрытом завинчивающейся крышкой, с контролем первого вскрытия. По 1 флакону помещают в пачку картонную вместе с инструкцией по применению."}},{"type":"paragraph","data":{"text":"По 10 таблеток в блистере. По 1, 3 или 10 блистеров помещают в картонную пачку вместе с инструкцией по применению.\n\n"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в сухом месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"\n\n3 года."}},{"type":"paragraph","data":{"text":"Не применять после истечения срока годности.\n\n"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"КРКА, д.д,, Ново место, Шмарьешка цеста 6, 8501 Ново место, Словения"}}]}],"source":null},"description_toggle":false,"short_description":"Фармакологические свойства Препарат компенсирует недостаточность внешнесекреторной функции поджелудочной железы. 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Улучшает процесс переваривания пищи у детей; стимулирует выделение собственных ферментов поджелудочной железы, желудка и тонкого кишечника, а также желчи. Фармакокинетика Панкреатические ферменты высвобождаются из лекарственной формы в щелочной среде тонкого кишечника, т.к. защищены от действия желудочного сока пленочной оболочкой. 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