Отхаркивающий (муколитический) препарат. Амброксол — активный метаболит бромгексина, принадлежит к бензиламиновой группе муколитических веществ. Разжижает мокроту за счет усиления выработки и повышения активности гидролитических ферментов, расщепляющих связи между мукополисахаридами мокроты. Улучшает реологические свойства мокроты, уменьшая ее вязкость и адгезивные свойства, за счет стимуляции серозных клеток желез слизистой оболочки бронхов и нормализации соотношения слизистого и серозного компонентов мокроты. Увеличивает мукоцилиарный транспорт, повышая двигательную активность мерцательного эпителия. Не вызывает чрезмерного образования секрета, уменьшает спастическую гиперреактивность бронхов. Способствует выработке сурфактанта. Эффект развивается через 30 мин после приема препарата.
Показания к применению
Острые и хронические заболевания органов дыхания, сопровождающиеся образованием вязкой мокроты: бронхит, бронхиальная астма, хроническая обструктивная болезнь легких, пневмония, бронхоэктатическая болезнь
Воспалительные заболевания ЛОР-органов (синуситы, отиты), при которых необходимо разжижение слизи
Противопоказания
Язвенное поражение ЖКТ
I триместр беременности
Период лактации (грудное вскармливание)
Повышенная чувствительность к амброксолу или бромгексину; С осторожностью следует применять препарат при почечной недостаточности тяжелой степени
Способ применения и дозы
Внутрь после еды, запивая большим количеством жидкости. Сироп можно принимать при помощи мерного стаканчика, находящегося в комплекте упаковки. Обильный прием жидкости способствует разжижению слизи при лечении Халиксолом. Взрослым и детям старше 12 лет: обычная суточная доза в первые 2-3 дня по 10 мл 3 раза/сут, а в последующие дни – по 10 мл 2 раза/сут или по 5 мл 3 раза/сут. В тяжелых случаях заболевания дозу не уменьшают в течение всего курса лечения. Детям в возрасте 5-12 лет назначают по 5 мл 2-3 раза/сут. Детям в возрасте 2-5 лет назначают по 2.5 мл сиропа 3 раза/сут. Детям в возрасте до 2 лет назначают по 2.5 мл сиропа 2 раза/сут. При почечной недостаточности тяжелой степени препарат следует назначать в низких дозах или увеличивать интервалы между приемами. Вопрос о необходимости приема Халиксола более 4-5 дней врач решает индивидуально.
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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