Установленный дефицит магния, изолированный или связанный с другими дефицитными состояниями, сопровождающийся такими симптомами, как повышенная раздражительность, незначительные нарушения сна, желудочно-кишечные спазмы, учащенное сердцебиение, повышенная утомляемость, боли и спазмы мышц, ощущение покалывания в мышцах.
Повышенная чувствительность к любому из компонентов препарата;
− тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин);
− возраст до 12 лет (эффективность и безопасность не установлены);
− наследственная галактоземия, синдром мальабсорбции глюкозы и галактозы или недостаточность лактазы (в связи с присутствием в составе препарата лактозы ...
Магнелис В6 форте — первый и единственный аналог французского магния цитрата и витамина В6. Магнелис В6 форте содержит в два раза больше магния по сравнению с классической формой.
Магнелис В6 с заботой о нервах.
Преимущества препарата Магнелис В6 форте.
Магнелис В6 форте — первый и единственный аналог французского магния цитрата и витамина В6 по доступной цене. Магнелис В6 форте содержит органичекую соль магния и магнезиефиксатор витамин В6, что обеспечивает ему легкое и полноценное усвоение. Прием Магнелис В6 форте помогает устранить дефицит магния, поддержит баланс и обменные процессы в нервной системе, восполняет уровень энергии и борется с утомляемостью, способствует улучшению настроения и сна, внимания и памяти, помогает выдержать повышенные нагрузки и противостоять стрессу.
Фармакотерапевтическая группа
Магния препарат
Фармакологические свойства
Фармакокинетика: Желудочно-кишечная абсорбция солей магниевых солей происходит частично путем пассивного механизма, в котором растворимость соли играет определяющую роль. Степень этой абсорбции не превосходит 50 %. Выведение происходит преимущественно почками. Фармакодинамика: Магний является жизненно важным элементом, который необходим для нормального функционирования клеток, участвует в большинстве реакций обмена веществ. В частности, он участвует в регуляции передачи нервных импульсов и сокращении мышц. 50 % количества магния, содержащегося в организме, накапливается в костной ткани.
Пиридоксин (витамин В6) участвует во многих метаболических процессах, способствует улучшению всасывания магния из желудочно-кишечного тракта и его проникновению в клетки.
Концентрация магния в сыворотке:
− в диапазоне 12 и17 мг/л (1 - 1,4 мЭкв/л или 0,5 - 0,7 ммоль/л): указывает на умеренный дефицит магния;
− ниже 12 мг/л (1 мЭкв/л или 0,5 ммоль/л): указывает на тяжелый дефицит магния.
Организм получает магний вместе с пищей. Недостаток магния в организме может наблюдаться при дефиците поступления или при увеличении потребности в магнии.
Показания к применению
Установленный дефицит магния, изолированный или связанный с другими дефицитными состояниями, сопровождающийся такими симптомами, как повышенная раздражительность, незначительные нарушения сна, желудочно-кишечные спазмы, учащенное сердцебиение, повышенная утомляемость, боли и спазмы мышц, ощущение покалывания в мышцах.
Если через месяц лечения отсутствует уменьшение этих симптомов, продолжение лечения нецелесообразно
Противопоказания
Повышенная чувствительность к любому из компонентов препарата;
− тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин);
− возраст до 12 лет (эффективность и безопасность не установлены);
− наследственная галактоземия, синдром мальабсорбции глюкозы и галактозы или недостаточность лактазы (в связи с присутствием в составе препарата лактозы моногидрата);
− одновременный прием леводопы (смотри «Взаимодействия с другими лекарственными средствами»).
С осторожностью
Умеренная почечная недостаточность (опасность развития гипермагниемии).
Применение при беременности и в период грудного вскармливания
Беременность
Клинический опыт применения комбинации магния цитрата и пиридоксина гидрохлорида у достаточного количества беременных женщин не выявил какого-либо неблагоприятного влияния на возникновение пороков развития плода или фетотоксического действия.
Препарат «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой» может применяться в период беременности только при необходимости, по рекомендации врача.
Период кормления грудью
Принимая во внимание, что магний проникает в материнское молоко, при необходимости приема препарата рекомендуется прекратить кормление грудью.
Способ применения и дозы
Таблетки следует принимать целиком, запивая стаканом воды.
Взрослые: 3-4 таблетки в сутки, разделенные на 2-3 приема, во время еды.
Дети старше 12 лет: 2-4 таблетки в сутки, разделенные на 2-3 приема, во время еды.
Обычно продолжительность приема препарата составляет один месяц.
Побочное действие
Частота развития побочных реакций классифицирована согласно рекомендациям Всемирной организации здравоохранения:
очень часто (> 10 %), часто (> 1 % и < 10 %), нечасто (> 0,1 % и < 1 %), редко (> 0,01 % и < 0,1 %), очень редко (> 0,01 %), неизвестная частота (когда по имеющимся данным не представляется возможным оценить частоту развития побочных реакций).
Нарушения со стороны иммунной системы:
очень редко (> 0,01 %): аллергические реакции, включая кожные реакции;
Нарушения о стороны желудочно-кишечного тракта:
Неизвестная частота (по имеющимся данным оценить частоту возникновения не является возможным): диарея, боли в животе, тошнота, рвота, метеоризм.
Передозировка
Симптомы
При нормальной функции почек передозировка магния при приеме внутрь обычно не приводит к возникновению токсических реакций. Однако, в случае почечной недостаточности может развитие отравления магнием.
Симптомы передозировки, выраженность которых зависит от концентрации магния в крови:
снижение артериального давления, тошнота, рвота; угнетение центральной нервной системы, снижение рефлексов; изменения на электрокардиограмме; угнетение дыхания, кома, остановка сердца и паралич дыхания, анурический синдром.
Лечение
Регидратация, форсированный диурез. При почечной недостаточности необходим гемодиализ или перитонеальный диализ.
Взаимодействие с другими лекарственными средствами
Перед назначением других лекарственных средств следует проинформировать врача или получить консультацию о возможности приема «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой».
Противопоказанные комбинации:
С леводопой: активность леводопы ингибируется пиридоксином (если прием этого препарата не сочетается с приемом ингибиторов периферической декарбоксилазы ароматических L-аминокислот). Следует избегать приема любого количества пиридоксина, если леводопа не принимается в сочетании с ингибиторами периферической декарбоксилазы ароматических L-аминокислот.
Нерекомендуемые комбинации:
Одновременное применение препаратов, содержащих фосфаты или соли кальция, может ухудшать всасывание магния в кишечнике.
Комбинации, которые следует принимать во внимание:
При назначении внутрь тетрациклинов необходимо соблюдать интервал не менее трех часов между приемом внутрь тетрациклина и «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой», так как препараты магния снижают всасывание тетрациклинов.
Особые указания
Препарат «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой» предназначен только для взрослых и детей старше 12 лет.
Препарат содержит лактозы моногидрат, поэтому его применение не рекомендуется пациентам с наследственной галактоземией, синдром мальабсорбции глюкозы и галактозы или недостаточностью лактазы.
При умеренной почечной недостаточности следует принимать препарат с осторожностью из-за риска развития гипермагниемии.
При одновременном дефиците кальция и магния, дефицит магния следует восполнять до начала приема препаратов кальция или пищевых добавок, содержащих кальций.
При применении пиридоксина в высоких дозах (более 200 мг в день) в течение длительного времени (в течение нескольких месяцев или в некоторых случаях – лет) может развиться сенсорная аксональная нейропатия, которая сопровождается такими симптомами, как онемение и нарушение проприоцептивной чувствительности, тремор дистальных отделов конечностей и постепенно развивающаяся сенсорная атаксия (нарушения координации движений).
Эти нарушения обычно являются обратимыми и проходят после отмены высоких доз витамина В6.
Влияние на способность управлять автомобилем и движущимися механизмами
По 10 таблеток в контурную ячейковую упаковку из пленки поливинилхлоридной или импортной ПВХ/ПВДХ, или ПВХ/Полиэтилен/ПВДХ и фольги алюминиевой печатной лакированной.
По 3, 6, 9 контурных ячейковых упаковок по 10 таблеток вместе с инструкцией по применению помещают в пачку из картона.
Условия хранения
При температуре не выше 25 °С.
Хранить в недоступном для детей месте.
Срок годности
2 года. Не применять по истечении срока годности, указанного на упаковке.
Условия отпуска
Без рецепта
Производитель
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номер","slug":"","body":[{"type":"paragraph","data":{"text":"ЛП-003224"}}]},{"id":2,"name":"Торговое название препарата","slug":"","body":[{"type":"paragraph","data":{"text":"Магнелис B6 форте"}}]},{"id":3,"name":"Лекарственная форма","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, покрытые пленочной оболочкой"}}]},{"id":4,"name":"Состав","slug":"ingredients","body":[{"type":"paragraph","data":{"text":"\n\nДействующие вещества:"}},{"type":"paragraph","data":{"text":"магния цитрат – 618,43 * мг, пиридоксина гидрохлорид – 10,00 мг."}},{"type":"paragraph","data":{"text":"Вспомогательные вещества: лудипресс [лактозы моногидрат – 92,20 мг - 96,05 мг, коллидон 30 – 3,04 мг - 4,05 мг, коллидон CL – 3,04 мг - 4,05 мг] – 101,21 мг, макрогол -6000 (полиэтиленгликоль - 6000) – 69,36 мг, магния стеарат – 1,00 мг."}},{"type":"paragraph","data":{"text":"Оболочка"}},{"type":"paragraph","data":{"text":"VIVACOAT®PM-1P-000 [гипромеллоза 6 сПз (гидроксипропилметилцеллюлоза 6 сПз) – 10,00 мг, титана диоксид – 6,00 мг, гипролоза (гидроксипропилцеллюлоза) – 1,00 мг, тальк – 2,00 мг, макрогол - 3350 (полиэтиленгликоль - 3350) – 1,00 мг] – 20,00 мг."}},{"type":"paragraph","data":{"text":"* – количество, эквивалентное 100 мг магния (Mg 2+)\n\n"}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"\n\nМагнелис В6 форте — первый и единственный аналог французского магния цитрата и витамина В6. Магнелис В6 форте содержит в два раза больше магния по сравнению с классической формой."}},{"type":"paragraph","data":{"text":"Магнелис В6 с заботой о нервах."}},{"type":"paragraph","data":{"text":"Преимущества препарата Магнелис В6 форте."}},{"type":"paragraph","data":{"text":"Магнелис В6 форте — первый и единственный аналог французского магния цитрата и витамина В6 по доступной цене. Магнелис В6 форте содержит органичекую соль магния и магнезиефиксатор витамин В6, что обеспечивает ему легкое и полноценное усвоение. Прием Магнелис В6 форте помогает устранить дефицит магния, поддержит баланс и обменные процессы в нервной системе, восполняет уровень энергии и борется с утомляемостью, способствует улучшению настроения и сна, внимания и памяти, помогает выдержать повышенные нагрузки и противостоять стрессу.\n\n"}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"Магния препарат"}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Фармакокинетика: Желудочно-кишечная абсорбция солей магниевых солей происходит частично путем пассивного механизма, в котором растворимость соли играет определяющую роль. Степень этой абсорбции не превосходит 50 %. Выведение происходит преимущественно почками. Фармакодинамика: Магний является жизненно важным элементом, который необходим для нормального функционирования клеток, участвует в большинстве реакций обмена веществ. В частности, он участвует в регуляции передачи нервных импульсов и сокращении мышц. 50 % количества магния, содержащегося в организме, накапливается в костной ткани."}},{"type":"paragraph","data":{"text":"Пиридоксин (витамин В6) участвует во многих метаболических процессах, способствует улучшению всасывания магния из желудочно-кишечного тракта и его проникновению в клетки."}},{"type":"paragraph","data":{"text":"Концентрация магния в сыворотке:"}},{"type":"paragraph","data":{"text":"− в диапазоне 12 и17 мг/л (1 - 1,4 мЭкв/л или 0,5 - 0,7 ммоль/л): указывает на умеренный дефицит магния;"}},{"type":"paragraph","data":{"text":"− ниже 12 мг/л (1 мЭкв/л или 0,5 ммоль/л): указывает на тяжелый дефицит магния."}},{"type":"paragraph","data":{"text":"Организм получает магний вместе с пищей. Недостаток магния в организме может наблюдаться при дефиците поступления или при увеличении потребности в магнии.\n\n"}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"\n\nУстановленный дефицит магния, изолированный или связанный с другими дефицитными состояниями, сопровождающийся такими симптомами, как повышенная раздражительность, незначительные нарушения сна, желудочно-кишечные спазмы, учащенное сердцебиение, повышенная утомляемость, боли и спазмы мышц, ощущение покалывания в мышцах."}},{"type":"paragraph","data":{"text":"Если через месяц лечения отсутствует уменьшение этих симптомов, продолжение лечения нецелесообразно\n\n"}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"\n\nПовышенная чувствительность к любому из компонентов препарата;"}},{"type":"paragraph","data":{"text":"− тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин);"}},{"type":"paragraph","data":{"text":"− возраст до 12 лет (эффективность и безопасность не установлены);"}},{"type":"paragraph","data":{"text":"− наследственная галактоземия, синдром мальабсорбции глюкозы и галактозы или недостаточность лактазы (в связи с присутствием в составе препарата лактозы моногидрата);"}},{"type":"paragraph","data":{"text":"− одновременный прием леводопы (смотри «Взаимодействия с другими лекарственными средствами»).\n\n"}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Умеренная почечная недостаточность (опасность развития гипермагниемии)."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"\n\nБеременность"}},{"type":"paragraph","data":{"text":"Клинический опыт применения комбинации магния цитрата и пиридоксина гидрохлорида у достаточного количества беременных женщин не выявил какого-либо неблагоприятного влияния на возникновение пороков развития плода или фетотоксического действия."}},{"type":"paragraph","data":{"text":"Препарат «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой» может применяться в период беременности только при необходимости, по рекомендации врача."}},{"type":"paragraph","data":{"text":"Период кормления грудью"}},{"type":"paragraph","data":{"text":"Принимая во внимание, что магний проникает в материнское молоко, при необходимости приема препарата рекомендуется прекратить кормление грудью.\n\n"}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"\n\nТаблетки следует принимать целиком, запивая стаканом воды."}},{"type":"paragraph","data":{"text":"Взрослые: 3-4 таблетки в сутки, разделенные на 2-3 приема, во время еды."}},{"type":"paragraph","data":{"text":"Дети старше 12 лет: 2-4 таблетки в сутки, разделенные на 2-3 приема, во время еды."}},{"type":"paragraph","data":{"text":"Обычно продолжительность приема препарата составляет один месяц.\n\n"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\n\nЧастота развития побочных реакций классифицирована согласно рекомендациям Всемирной организации здравоохранения:"}},{"type":"paragraph","data":{"text":"очень часто (> 10 %), часто (> 1 % и < 10 %), нечасто (> 0,1 % и < 1 %), редко (> 0,01 % и < 0,1 %), очень редко (> 0,01 %), неизвестная частота (когда по имеющимся данным не представляется возможным оценить частоту развития побочных реакций)."}},{"type":"paragraph","data":{"text":"Нарушения со стороны иммунной системы:"}},{"type":"paragraph","data":{"text":"очень редко (> 0,01 %): аллергические реакции, включая кожные реакции;"}},{"type":"paragraph","data":{"text":"Нарушения о стороны желудочно-кишечного тракта:"}},{"type":"paragraph","data":{"text":"Неизвестная частота (по имеющимся данным оценить частоту возникновения не является возможным): диарея, боли в животе, тошнота, рвота, метеоризм.\n\n"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\n\nСимптомы"}},{"type":"paragraph","data":{"text":"При нормальной функции почек передозировка магния при приеме внутрь обычно не приводит к возникновению токсических реакций. Однако, в случае почечной недостаточности может развитие отравления магнием."}},{"type":"paragraph","data":{"text":"Симптомы передозировки, выраженность которых зависит от концентрации магния в крови:"}},{"type":"paragraph","data":{"text":"снижение артериального давления, тошнота, рвота; угнетение центральной нервной системы, снижение рефлексов; изменения на электрокардиограмме; угнетение дыхания, кома, остановка сердца и паралич дыхания, анурический синдром."}},{"type":"paragraph","data":{"text":"Лечение"}},{"type":"paragraph","data":{"text":"Регидратация, форсированный диурез. При почечной недостаточности необходим гемодиализ или перитонеальный диализ.\n\n"}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\n\nПеред назначением других лекарственных средств следует проинформировать врача или получить консультацию о возможности приема «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой»."}},{"type":"paragraph","data":{"text":"Противопоказанные комбинации:"}},{"type":"paragraph","data":{"text":"С леводопой: активность леводопы ингибируется пиридоксином (если прием этого препарата не сочетается с приемом ингибиторов периферической декарбоксилазы ароматических L-аминокислот). Следует избегать приема любого количества пиридоксина, если леводопа не принимается в сочетании с ингибиторами периферической декарбоксилазы ароматических L-аминокислот."}},{"type":"paragraph","data":{"text":"Нерекомендуемые комбинации:"}},{"type":"paragraph","data":{"text":"Одновременное применение препаратов, содержащих фосфаты или соли кальция, может ухудшать всасывание магния в кишечнике."}},{"type":"paragraph","data":{"text":"Комбинации, которые следует принимать во внимание:"}},{"type":"paragraph","data":{"text":"При назначении внутрь тетрациклинов необходимо соблюдать интервал не менее трех часов между приемом внутрь тетрациклина и «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой», так как препараты магния снижают всасывание тетрациклинов.\n\n"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nПрепарат «Магнелис В6 форте, таблетки, покрытые пленочной оболочкой» предназначен только для взрослых и детей старше 12 лет."}},{"type":"paragraph","data":{"text":"Препарат содержит лактозы моногидрат, поэтому его применение не рекомендуется пациентам с наследственной галактоземией, синдром мальабсорбции глюкозы и галактозы или недостаточностью лактазы."}},{"type":"paragraph","data":{"text":"При умеренной почечной недостаточности следует принимать препарат с осторожностью из-за риска развития гипермагниемии."}},{"type":"paragraph","data":{"text":"При одновременном дефиците кальция и магния, дефицит магния следует восполнять до начала приема препаратов кальция или пищевых добавок, содержащих кальций."}},{"type":"paragraph","data":{"text":"При применении пиридоксина в высоких дозах (более 200 мг в день) в течение длительного времени (в течение нескольких месяцев или в некоторых случаях – лет) может развиться сенсорная аксональная нейропатия, которая сопровождается такими симптомами, как онемение и нарушение проприоцептивной чувствительности, тремор дистальных отделов конечностей и постепенно развивающаяся сенсорная атаксия (нарушения координации движений)."}},{"type":"paragraph","data":{"text":"Эти нарушения обычно являются обратимыми и проходят после отмены высоких доз витамина В6.\n\n"}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Не влияет. Особых рекомендаций нет."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, покрытые пленочной оболочкой, 100 мг + 10 мг."}},{"type":"paragraph","data":{"text":"По 10 таблеток в контурную ячейковую упаковку из пленки поливинилхлоридной или импортной ПВХ/ПВДХ, или ПВХ/Полиэтилен/ПВДХ и фольги алюминиевой печатной лакированной."}},{"type":"paragraph","data":{"text":"По 3, 6, 9 контурных ячейковых упаковок по 10 таблеток вместе с инструкцией по применению помещают в пачку из картона.\n\n"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"\n\nПри температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте.\n\n"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Не применять по истечении срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nОАО \"Фармстандарт-Томскхимфарм\""}},{"type":"paragraph","data":{"text":"или ООО «Нанолек»\n\n"}}]}],"source":null},"description_toggle":false,"short_description":"Фармакокинетика: Желудочно-кишечная абсорбция солей магниевых солей происходит частично путем пассивного механизма, в котором растворимость соли играет определяющую роль. Степень этой абсорбции не превосходит 50 %. Выведение происходит преимущественно почками. Фармакодинамика: Магний является жизненно важным элементом, который необходим для нормального функционирования клеток, участвует в большинстве реакций обмена веществ. В частности, он участвует в регуляции передачи нервных импульсов и сокращении мышц. 50 % количества магния, содержащегося в организме, накапливается в костной ткани. Пиридоксин (витамин В6) участвует во многих метаболических процессах, способствует улучшению всасывания магния из желудочно-кишечного тракта и его проникновению в клетки. Концентрация магния в сыворотке: − в диапазоне 12 и17 мг/л (1 - 1,4 мЭкв/л или 0,5 - 0,7 ммоль/л): указывает на умеренный дефицит магния; − ниже 12 мг/л (1 мЭкв/л или 0,5 ммоль/л): указывает на тяжелый дефицит магния. Организм получает магний вместе с пищей. Недостаток магния в организме может наблюдаться при дефиците поступления или при увеличении потребности в магнии.","substance":[],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":true,"comments":null,"image_alt":"Магнелис В6 форте","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/224386/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/224386/share_default/"}},"diseases":[{"id":"424","title":"Недостаточность магния","slug":"424-nedostatochnost_magniya"},{"id":"509","title":"Расстройства режима сна и бодрствования неорганической этиологии","slug":"509-rasstroystva_rezhima_sna_i_bodrstvovaniya_neorganicheskoy_etiologii"},{"id":"1250","title":"Другие и неуточненные боли в области живота (колика)","slug":"1250-drugie_i_neutochnennye_boli_v_oblasti_zhivota_kolika"},{"id":"1259","title":"Парестезия кожи","slug":"1259-paresteziya_kozhi"},{"id":"1262","title":"Судорога и 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