Эрмиталь Капсулы, 50 шт, 36000 ед

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Входящие в состав ферменты (липаза, альфа-амилаза, трипсин, химотрипсин), способствуют расщеплению белков до аминокислот, жиров — до глицерина и жирных кислот, крахмала — до декстринов и моносахаридов, улучшают функциональное состояние желудочно-кишечного тракта, нормализуют процессы пищеварения. Продукты расщепления панкреатическими ферментами всасываются в кишечнике либо непосредственно, либо после расщепления кишечными ферментами."}},{"type":"paragraph","data":{"text":"\u003ci\u003e\u003cb\u003eФармакокинетика\u003c/b\u003e\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Форма выпуска препарата обеспечивает полное высвобождение резистентных к действию желудочного сока микротаблеток из капсулы в желудке с последующим мелкодисперсным перемешиванием микротаблеток с кишечным содержимым и химусом и быстрым выделением ферментов из микротаблеток в двенадцатиперстной кишке."}},{"type":"paragraph","data":{"text":"Ферменты поджелудочной железы не всасываются в кровь. Ферменты инактивируются и перевариваются в кишечнике как белки путем аутолиза и протеолиза."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"У взрослых и детей:"}},{"type":"list","data":{"style":"ordered","items":["для улучшения переваривания пищи у пациентов с нормальной функцией желудочно-кишечного тракта в случае погрешностей в питании;","заместительная терапия при внешнесекреторной недостаточности поджелудочной железы: муковисцидоз, хронический панкреатит, панкреатэктомия, рак поджелудочной железы, протоковая обструкция вследствие новообразования (в т.ч. обструкция протоков поджелудочной железы, общего желчного протока), синдром Швахмана-Даймонда, состояния после приступа острого панкреатита и возобновления питания;","симптоматическая терапия нарушений пищеварения: состояние после холецистэктомии, частичная резекция желудка (Бильрот-I/II), тотальная гастрэктомия, дуодено- и гастростаз, билиарная обструкция, холестатический гепатит, цирроз печени, болезнь Крона, дисбактериоз."]}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Известная гиперчувствительность к любому из компонентов препарата."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"  Применение препарата Эрмиталь при беременности и в период лактации возможно только после тщательной оценки соотношения пользы для матери и риска для плода или младенца. В связи с незначительной системной абсорбцией панкреатина, негативного влияния на организм матери, а также плода и младенца, не ожидается.  "}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь, дозы подбирают индивидуально в зависимости от тяжести заболевания и диеты."}},{"type":"paragraph","data":{"text":"Расчет дозы проводится в перерасчете на единицы активности липазы. Капсулы следует проглатывать целиком во время приема пищи, запивая большим количеством жидкости (вода, соки); при затруднении глотания капсулы можно вскрыть и их содержимое добавить к жидкой пище, имеющей кислый вкус (pH<5,5), или высыпать содержимое капсул в рот и проглотить их, не разжевывая и запивая большим количеством жидкости (около стакана воды). Размельчение, разжевывание микротаблеток или добавление их к пище с рН>5,5 приводит к разрушению их оболочки, защищающей от действия желудочного сока. Это может привести к раннему высвобождению ферментов в полости рта, снижению эффективности и раздражению слизистых оболочек. Необходимо убедиться, что во рту не осталось микротаблеток."}},{"type":"paragraph","data":{"text":"\u003ci\u003eМуковисцидоз\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Доза зависит от массы тела и должна составлять в начале лечения 1000 липазных единиц/кг на каждый прием пищи для детей младше четырех лет и 500 липазных единиц/кг во время приема пищи для детей старше четырех лет и взрослых."}},{"type":"paragraph","data":{"text":"Дозу следует определять в зависимости от выраженности симптомов заболевания, результатов контроля за стеатореей и поддержания адекватного нутритивного статуса. У большинства пациентов доза должна оставаться меньше или не превышать 10 000 липазных единиц/кг массы тела в сутки или 4 000 липазных единиц/г потребленного жира."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДругие состояния, сопровождающиеся экзокринной недостаточностью поджелудочной железы\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Рекомендуемая доза составляет 2-4 капсулы препарата Эрмиталь 10 000 ЕД, или 1-2 капсулы препарата Эрмиталь 25 000 ЕД, или 1 капсула препарата Эрмиталь 36 000 ЕД во время каждого приема пищи. При необходимости доза может быть увеличена. Повышение дозы должно проходить под контролем врача. Нельзя превышать суточную дозу ферментов в пределах 15-20 тыс. липазных единиц на кг массы тела. Терапия должна проводиться на фоне обильного приема жидкости."}},{"type":"paragraph","data":{"text":"У детей препарат должен применяться в соответствии с назначением врача."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны желудочно-кишечного тракта\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Очень часто (≥1/10): боль в области живота."}},{"type":"paragraph","data":{"text":"Часто (≥1/100, <1/10): тошнота, рвота, запор, вздутие живота, диарея."}},{"type":"paragraph","data":{"text":"Частота неизвестна: стриктуры подвздошной, слепой и толстой кишки (фиброзирующая колонопатия)."}},{"type":"paragraph","data":{"text":"Желудочно-кишечные расстройства связаны главным образом с основным заболеванием. Частота возникновения таких нежелательных реакций как боль в области живота и диарея была ниже или схожей с таковой при применении плацебо. Стриктуры подвздошной, слепой и толстой кишки (фиброзирующая колонопатия) наблюдались у пациентов с муковисцидзом, получавших высокие дозы препаратов панкреатина (см. раздел «Особые указания»)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны кожи и подкожных тканей\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Нечасто (≥1/1000, <1/100): сыпь."}},{"type":"paragraph","data":{"text":"Частота неизвестна: зуд, крапивница."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны иммунной системы\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Частота неизвестна: гиперчувствительность (анафилактические реакции)."}},{"type":"paragraph","data":{"text":"Аллергические реакции наблюдались преимущественно со стороны кожных покровов, но отмечались также и другие проявления аллергии. Сообщения о данных побочных эффектах были получены в период постмаркетингового применения и носили спонтанный характер. Для точной оценки частоты случаев имеющихся данных недостаточно."}},{"type":"paragraph","data":{"text":"При применении у детей не было отмечено каких-либо специфических нежелательных реакций. Частота, тип и степень тяжести нежелательных реакций у детей с муковисцидозом были сходны с таковыми у взрослых."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"При приеме панкреатина в высоких дозах возможно развитие гиперурикозурии и гиперурикемии, особенно у пациентов с муковисцидозом."}},{"type":"paragraph","data":{"text":"Лечение: отмена препарата, симптоматическая терапия."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"  При приеме препарата Эрмиталь может снижаться всасывание фолиевой кислоты. На фоне лечения препаратом Эрмиталь может снижаться эффект пероральных гипогликемических лекарственных средств акарбозы и миглитола.  "}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"При длительном применении панкреатина в высоких дозах у пациентов с муковисцидозом возможно развитие запоров, стриктур подвздошной и слепой кишки (фиброзирующая колонопатия), колит."}},{"type":"paragraph","data":{"text":"При приеме препарата в высоких дозах (более 10 000 липазных единиц/кг массы тела в сутки) следует тщательно контролировать необычные симптомы и побочные эффекты со стороны органов желудочно-кишечного тракта и, при необходимости, проводить медицинское обследование для исключения фиброзирующей колонопатии."}},{"type":"paragraph","data":{"text":"Препарат Эрмиталь содержит активные ферменты, которые при высвобождении в полости рта (например, при жевании) могут вызвать раздражение и изъязвление слизистой оболочки. Поэтому микротаблетки следует глотать, не разжевывая."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат не влияет на способность управлять транспортными средствами, механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы \u003ca href=\"https://www.stada.ru/products/ermital.html#\"\u003e10 000 ЕД\u003c/a\u003e, \u003ca href=\"https://www.stada.ru/products/ermital.html#\"\u003e25 000 ЕД\u003c/a\u003e, \u003ca href=\"https://www.stada.ru/products/ermital.html#\"\u003e36 000 ЕД\u003c/a\u003e."}},{"type":"paragraph","data":{"text":"По 20 или 50 капсул в стеклянный флакон темного стекла, укупоренный пластмассовой крышкой, флакон снабжен уплотнительным диском, состоящим из двух частей, скрепленных восковыми точками."}},{"type":"paragraph","data":{"text":"При первом вскрытии диск разделяется на две части. Часть 1 (пергамин/ алюминиевая фольга/ восковые точки) остается на горловине флакона, а часть 2 (алюминиевая фольга/ бумага/ картон) остается в крышке."}},{"type":"paragraph","data":{"text":"По 1 флакону в картонную пачку вместе с инструкцией по медицинскому применению лекарственного препарата."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре не выше 25 ˚С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте!"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. Не использовать по истечении срока годности, указанного на упаковке.ользовать по истечении срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта врача."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\n«Нордмарк Арцнаймиттель ГмбХ и Ко. КГ», Германия"}},{"type":"paragraph","data":{"text":"Пиннауаллее 4, 25436 Ютерсен\n\n"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"\n\nАО «Нижфарм», Россия"}},{"type":"paragraph","data":{"text":"603950, г. Нижний Новгород, ул. Салганская, д. 7"}},{"type":"paragraph","data":{"text":"Тел.: (831) 278-80-88; факс: (831) 430-72-28"}},{"type":"paragraph","data":{"text":"E-mail: E-mail: \u003ca href=\"mailto:med@stada.ru\"\u003emed@stada.ru\u003c/a\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"ФармакодинамикаЭрмиталь содержит стандартный высокоактивный панкреатин, полученный из поджелудочной железы свиньи в виде микротаблеток, резистентных к воздействию желудочного сока. Пищеварительное ферментное средство, восполняет дефицит ферментов поджелудочной железы, оказывает протеолитическое, амилолитическое и липолитическое действие. Входящие в состав ферменты (липаза, альфа-амилаза, трипсин, химотрипсин), способствуют расщеплению белков до аминокислот, жиров — до глицерина и жирных кислот, крахмала — до декстринов и моносахаридов, улучшают функциональное состояние желудочно-кишечного тракта, нормализуют процессы пищеварения. Продукты расщепления панкреатическими ферментами всасываются в кишечнике либо непосредственно, либо после расщепления кишечными ферментами.ФармакокинетикаФорма выпуска препарата обеспечивает полное высвобождение резистентных к действию желудочного сока микротаблеток из капсулы в желудке с последующим мелкодисперсным перемешиванием микротаблеток с кишечным содержимым и химусом и быстрым выделением ферментов из микротаблеток в двенадцатиперстной кишке. Ферменты поджелудочной железы не всасываются в кровь. Ферменты инактивируются и перевариваются в кишечнике как белки путем аутолиза и протеолиза.","substance":[{"id":119,"title":"Панкреатин","title_latin":"Pancreatinum","slug":"pankreatin_119"}],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":false,"comments":null,"image_alt":"Эрмиталь - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/17215/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/17215/share_default/"}},"diseases":[{"id":"221","title":"Злокачественное новообразование поджелудочной железы","slug":"221-zlokachestvennoe_novoobrazovanie_podzheludochnoy_zhelezy"},{"id":"872","title":"Болезнь Крона [регионарный энтерит]","slug":"872-bolezn_krona_regionarnyy_enterit"},{"id":"896","title":"Фиброз и цирроз печени","slug":"896-fibroz_i_tsirroz_pecheni"},{"id":"909","title":"Закупорка желчного протока","slug":"909-zakuporka_zhelchnogo_protoka"},{"id":"912","title":"Другие 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путей","slug":"3184-diskineziya_zhelchnogo_puzyrya_i_zhelchnyh_putey"},{"id":"3185","title":"Гипофункция поджелудочной железы внешнесекреторная","slug":"3185-gipofunktsiya_podzheludochnoy_zhelezy_vneshnesekretornaya"},{"id":"3186","title":"КЛАСС XXII Хирургическая практика","slug":"3186-klass_xxii_hirurgicheskaya_praktika"},{"id":"3187","title":"Неприемлемая диета и вредные привычки в питании","slug":"3187-nepriemlemaya_dieta_i_vrednye_privychki_v_pitanii"}],"other_packages":[{"id":95420,"title":"Эрмиталь","subtitle":{"full":"Капсулы, 20 шт, 36000 ед","short":"Капсулы, 20 шт, 36000 ед","package":"20 шт, 36000 ед"},"prescription":false,"catalog_section_id":139,"manufacturer":{"id":2332,"title":"Нижфарм","slug":"nizhfarm_2332","logo":{"isTouch":{"retina":null,"default":null},"isFromTablet":{"retina":null,"default":null}}},"is_advert":false,"product_form":"Капсулы","slug":"95420-ermital","attributes":{"count":"20 шт","dose":"36000 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