Противомикробное бактериостатическое средство сульфаниламид. Инструкция
Показания к применению
В составе комплексной терапии. Конъюнктивит и блефарит у детей и взрослых гнойная язва роговицы профилактика и лечение бленнореи у новорожденных гонорейные и хламидийные заболевания глаз у взрослых.
Противопоказания
Повышенная чувствительность к компонентам препарата.
Вспомогательные вещества: натрия дисульфит (натрия пиросульфит) 5 г натрия гидроксид (1 М раствор натрия гидроксида) до рН 7,7-8,7вода очищенная до 1 л
Описание
Прозрачная бесцветная или слегка окрашенная жидкость.
Фармакотерапевтическая группа
Противомикробное средство - сульфаниламид
Фармакологические свойства
Фармакодинамика:
Противомикробное бактериостатическое средство сульфаниламид.Механизм действия обусловлен конкурентным антагонизмом с парааминобензойной кислотой и угнетением дигидроптероатсинтетазы нарушением синтеза тетрагидрофолиевой кислоты необходимой для синтеза пуринов и пиримидинов.Активен в отношении грамположительных и грамотрицательных кокковEscherichia coli Shigella spp. Vibrio cholerae Clostridium perfringens Bacillus anthracis Corynebacterium diphtheriae Yersinia pestis Chlamydia spp. Actinomyces israelii Toxoplasma gondii.
Фармакокинетика:
При местном применении максимальная концентрация (Сmах) сульфаниламидов в роговице (около 3 мг/мл) влаге передней камеры (около 0.5 мг/мл) и радужке (около 0.1 мг/мл) достигается за первые 30 мин после аппликации. Некоторое количество (менее 0.5 мг/мл) сохраняется в тканях глазного яблока в течение 3-4 ч. При повреждении эпителия роговицы пенетрация сульфаниламидов усиливается.
Показания к применению
В составе комплексной терапии. Конъюнктивит и блефарит у детей и взрослых гнойная язва роговицы профилактика и лечение бленнореи у новорожденных гонорейные и хламидийные заболевания глаз у взрослых.
Противопоказания
Повышенная чувствительность к компонентам препарата.
Применение при беременности и в период грудного вскармливания
Достаточного опыта по применению препарата во время беременности кормления грудью нет. Возможно применение сульфацетамида для лечения беременных и кормящих матерей по назначению лечащего врача если ожидаемый лечебный эффект превышает риск развития возможных побочных эффектов.
Способ применения и дозы
Местно. Для лечения конъюнктивита у детей и взрослых закапывают в конъюнктивальный мешок через каждый час по 1-2 капле в последующие 3-4 дня - 5-6 раз в день. Для лечения блефарита у детей и взрослых частота инсталляций впервые дни составляет до 6-8 раз и уменьшается до 3-4 раз в день по мере улучшения состояния длительность лечения 3-5 дней. Для лечения гнойной язвы роговицы в составе комплексной терапии в виде инсталляций 5-6 раз в день в течение 5-7 дней. С целью профилактики бленнореи у новорожденных по 2 капли в каждый конъюнктивальный мешок непосредственно после рождения и по 2 капли -через 2 часа в течение суток для лечения бленнореи - в каждый конъюнктивальный мешок по 2 капли каждые 1 -2 часа впервые сутки затем каждые 3 часа продолжительность лечения две недели. При лечении гонорейных и хламидийных заболевания глаз у взрослых в составе комплексной терапии по 1-2 капле 5-6 раз в день в течение 4-6 недель. При положительной динамике на фоне проводимого лечения число инсталляций капель уменьшают в каждую последующую неделю.
Побочное действие
Жжение слезотечение резь зуд в глазах преходящее затуманивание зрения после закапывания аллергические реакции.
Передозировка
Данные по передозировке препарата отсутствуют.
Взаимодействие с другими лекарственными средствами
Совместное применение с прокаином и тетракаином снижает бактериостатический эффект. Несовместимость с солями серебра.
Особые указания
Пациенты обладающие повышенной чувствительностью к фуросемиду тиазидным диуретикам сульфонилмочевине или ингибиторам карбоангидразы могут иметь повышенную чувствительность к сульфацетамиду. После вскрытия использовать в течение 14 суток.
Влияние на способность управлять автомобилем и движущимися механизмами
Если у пациента после применения препарата временно снижается четкость зрительного восприятия до ее восстановления не рекомендуется управлять автомобилем и заниматься вилами деятельности требующими повышенного внимания и реакции.
Форма выпуска
Капли глазные 20 %.
Условия хранения
В защищенном от света месте при температуре не выше от 2 до 15 °С. Хранить в недоступном для детей месте.
Срок годности
2 года.
Не использовать по истечении срока годности указанного на упаковке.
Условия отпуска
Без рецепта
Производитель
АО "Производственная фармацевтическая компания Обновление" (АО "ПФК Обновление"), г. Новосибирск, ул. Станционная, д.80, Россия
Организация, принимающая претензии потребителей
АО "ПФК Обновление"
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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