Сульфацил-натрия - противомикробное бактериостатическое средство, сульфаниламид. Механизм действия связан с конкурентным антагонизмом с ПАБК и угнетением дигидроптероатсинтетазы, что приводит к нарушению синтеза дигидрофолиевой кислоты, необходимой для синтеза пуринов и пиримидинов.
Активен в отношении грамположительных и грамотрицательных кокков, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.
Фармакокинетика
При местном применении практически не всасывается.
Показания к применению
Препарат применяют при: коньюктивитах, блефаритах, гнойных язвах роговицы и других инфекционных заболеваниях глаз.
Профилактика и лечение бленнореи у новорожденных.
Противопоказания
Повышенная чувствительность к препарату Сульфацил-натрия.
Способ применения и дозы
В конъюнктивальный мешок закапывают по 1-2 капли 5-6 раз в сутки.
Для профилактики бленнореи у новорожденных по 2 капли в каждый конъюнктивальный мешок непосредственно после рождения и по 2 капли – через 2 часа.
Взаимодействие с другими лекарственными средствами
Совместное применение с новокаином и дикаином снижает бактериостатический эффект сульфацила натрия.
Наблюдается несовместимость сульфацила натрия при его совместном применении с солями серебра.
Особые указания
У пациентов с повышенной индивидуальной чувствительностью к фуросемиду, тиазидным диуретикам, сульфонилмочевине или ингибиторам карбонгидразы может проявляться повышенная чувствительность к сульфацилу натрия.
Форма выпуска
Капли глазные.
Условия хранения
В защищенном от света месте, при температуре 8–15 °C.
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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