Миролют Таблетки, 4 шт, 200 мкг

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Применение препарата требует предупреждения резус-конфликта и других общих мероприятий, сопутствующих аборту."}},{"type":"paragraph","data":{"text":"Внутрь, через 36-48 часов после приема 600 мг (3 таблетки) мифепристона назначают 400 мкг (2 таблетки) препарата Миролют."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Боль в нижней части живота, головокружение, головная боль, тошнота, рвота, метеоризм, диарея, вялость, \"приливы\" крови к лицу, повышение температуры тела, аллергические реакции (кожная сыпь, зуд, ангионевротический отек)."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптомы: сонливость, заторможенность, тремор, судороги, одышка, боль в животе, диарея, лихорадка, сердцебиение, снижение артериального давления, брадикардия."}},{"type":"paragraph","data":{"text":"Лечение: симптоматическое, гемодиализ неэффективен."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При сочетании с магнийсодержащими антацидами возможно усиление диареи."}},{"type":"paragraph","data":{"text":"Прием пищи, антациды уменьшают концентрацию мизопростоловой кислоты в плазме (клинически незначимо)."}},{"type":"paragraph","data":{"text":"Мизопростол не оказывает клинически значимого влияния на абсорбцию, концентрацию в крови и антиагрегантный эффект ацетилсалициловой кислоты, при приеме последней в терапевтических дозах, а также на фармакокинетику диклофенака и ибупрофена."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"В сочетании с мифепристоном мизопростол должен применяться только по назначению и под наблюдением врача акушера-гинеколога, и только в специализированных лечебных учреждениях, располагающих возможностями оказания экстренной хирургической гинекологической и гемотрансфузионной помощи. Применение препарата требует предупреждения резус-конфликта и других общих мероприятий, сопутствующих аборту."}},{"type":"paragraph","data":{"text":"Перед назначением мизопростола пациентка должна быть подробно проинформирована о фармакологическом действии и возможных побочных эффектах препарата."}},{"type":"paragraph","data":{"text":"Пациентка должна наблюдаться в условиях лечебного учреждения в течение 2-3 часов после приёма препарата. После приема мизопростола, как правило, возникает небольшое вагинальное кровотечение, у части женщин - весьма продолжительное. В случае массивного кровотечения или развития других осложнений пациентке должна быть оказана своевременная медицинская помощь. В 80% случаев самопроизвольный аборт происходит в течение 6 часов, в 10% - в течение 1 недели. При очень раннем сроке беременности самопроизвольный аборт возможен уже после приема одного мифепристона, однако в этом случае все равно необходим приём мизопростола для оптимизации медикаментозного воздействия."}},{"type":"paragraph","data":{"text":"Через 10-14 дней пациентке необходимо пройти повторное обследование в том же лечебном учреждении. При необходимости проводят ультразвуковое исследование (УЗИ) или определение уровня хорионического гонадотропина в сыворотке крови."}},{"type":"paragraph","data":{"text":"При подозрении на незавершенный аборт или сохранение беременности, оцениваемые на 10-14 день после приема мифепристона, проводят вакуумаспирацию с последующим гистологическим исследованием аспирата."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Учитывая возможные побочные эффекты препарата (головокружение), рекомендуется соблюдать осторожность при вождении автотранспорта и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, 200 мкг. По 4 или 10 таблеток в контурную ячейковую упаковку из пленки поливинилхлоридной / поливинилиденхлоридной и фольги алюминиевой печатной лакированной."}},{"type":"paragraph","data":{"text":"По 4, 10, 20 или 30 таблеток в банку полимерную для лекарственных средств с контролем первого вскрытия, укупоренную крышкой с силикагелем. На банку наклеивают этикетку из бумаги этикеточной или писчей."}},{"type":"paragraph","data":{"text":"По 1 банке или 1, 2, 3, 4 или 10 контурных ячейковых упаковок вместе с инструкцией по медицинскому применению лекарственного препарата помещают в пачку картонную."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В сухом, защищенном от света месте, при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. Не применять по истечении срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпуск только в медицинские акушерско-гинекологические учреждения, относящиеся к государственной системе здравоохранения, а также в учреждения муниципальной и частной собственности, имеющие лицензии на этот род деятельности."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ЗАО «Обнинская химико-фармацевтическая компания», Россия"}},{"type":"paragraph","data":{"text":"249036, Калужская область, г. Обнинск,"}},{"type":"paragraph","data":{"text":"ул. Королева, д. 4"}},{"type":"paragraph","data":{"text":"Тел./факс: (48439) 6-47-41"}},{"type":"paragraph","data":{"text":"Адрес места производства"}},{"type":"paragraph","data":{"text":"Калужская область, г. Обнинск, Киевское шоссе, зд. 103, зд. 107"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"\n\nАО «Нижфарм», Россия"}},{"type":"paragraph","data":{"text":"603950, г. Нижний Новгород, ГСП-459, ул. Салганская, д. 7"}},{"type":"paragraph","data":{"text":"Тел.: (831) 278-80-88; факс:(831) 430-72-28"}},{"type":"paragraph","data":{"text":"E-mail: \u003ca href=\"mailto:med@nizhpharm.ru\"\u003emed@\u003c/a\u003e\u003ca href=\"mailto:med@nizhpharm.ru\"\u003estada.ru\u003c/a\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"Мизопростол - синтетическое производное простагландина Е1. Мизопростол индуцирует сокращение гладких мышечных волокон миометрия и расширяет шейку матки, что облегчает удаление содержимого полости матки. Повышает частоту и силу сокращений миометрия, оказывает слабое стимулирующее действие на гладкую мускулатуру желудочно-кишечного тракта (ЖКТ). При пероральном применении быстро и полно абсорбируется (пища снижает абсорбцию). В стенках ЖКТ и печени метаболизируется до фармакологически активной мизопростоловой кислоты. Время достижения максимальной концентрации мизопростоловой кислоты - 9-15 минут, максимальная концентрация (Cmax) – 1 мкг/л, период полувыведения (T1/2) - 20-40 мин. Связь с белками плазмы - 85%. Выводится почками - 64-73% в течение первых 24 часов (56% в течение первых 8 часов) и с желчью (15% в течение первых 24 часов). При нарушении функции почек Cmax может повышаться почти в 2 раза, удлиняться T1/2. Не кумулирует.","substance":[{"id":2211,"title":"Мизопростол","title_latin":null,"slug":"mizoprostol"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Миролют - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/18349/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/18349/share_default/"}},"diseases":[],"other_packages":[],"other_product_forms":[],"related_products":{"title":"Похожие товары","type":"nondrugs","products":[{"id":99732,"title":"Клостилбегит","subtitle":{"full":"Таблетки, коробка, 10 шт, 50 мг, для приема внутрь","short":"Таблетки, 10 шт, 50 мг","package":"10 шт, 50 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