Кардионат Раствор, 10 шт, 5 мл, 100 мг / мл, для инъекций, для взрослых

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Период полувыведения составляет 3-6 часов."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eВ комплексной терапии:\u003c/i\u003e ишемическая болезнь сердца (стенокардия, инфаркт миокарда), хроническая сердечная недостаточность, кардиалгия на фоне дисгормональной дистрофии миокарда."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВ комплексной терапии:\u003c/i\u003e нарушения мозгового кровообращения (ишемический инсульт, цереброваскулярная недостаточность)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВ комплексной терапии:\u003c/i\u003e острое нарушение кровообращения в сетчатке, гемофтальм и кровоизлияния в сетчатку различной этиологии, тромбоз центральной вены сетчатки и ее ветвей, ретинопатии различной этиологии (в том числе диабетическая и гипертоническая) — только для парабульбарного введения."}},{"type":"paragraph","data":{"text":"Сниженная работоспособность, физическое перенапряжение (в том числе у спортсменов). Абстинентный алкогольный синдром \u003ci\u003e(в составе комплексной специфической терапии\u003c/i\u003e)."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к препарату; повышение внутричерепного давления (при нарушении венозного оттока и внутричерепных опухолях); беременность, период лактации, возраст до 18 лет."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Заболевания печени и/или почек."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Противопоказано применение препарата при беременности и в период грудного вскармливания."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Ввиду возможного возбуждающего эффекта препарат рекомендуется применять в первой половине дня."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСтенокардия и инфаркт миокарда\u003c/i\u003e (в составе комбинированной терапии): внутривенно (в/в) по 0,5-1 г (5-10 мл раствора для инъекций 100 мг/1 мл) 1 раз в сутки, затем переходят на прием препарата внутрь."}},{"type":"paragraph","data":{"text":"\u003ci\u003eХроническая сердечная недостаточность \u003c/i\u003e(в составе комбинированной терапии): в/в по 0,5-1 г (5-10 мл раствора для инъекций) 1 раз в сутки; курс лечения — 10-14 дней, затем переходят на прием препарата внутрь."}},{"type":"paragraph","data":{"text":"\u003ci\u003eКардиалгия на фоне дисгормональной дистрофии миокарда:\u003c/i\u003e в/в по 0,5-1 г (5-10 мл раствора для инъекций) 1 раз в сутки или в/м по 0,5 г 1-2 раза в сутки; курс лечения — 10-14 дней, затем переходят на прием препарата внутрь."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушение мозгового кровообращения \u003c/i\u003e(в составе комбинированной терапии): острая фаза — в/в по 500 мг (5 мл раствора для инъекций) 1 раз в сутки в течение 10 дней, затем возможен переход на пероральный прием;\u003ci\u003e хронические нарушения мозгового кровообращения: \u003c/i\u003eв/м по 500 мг (5 мл раствора для инъекций) 1 раз в сутки; курс лечения 10-14 дней, затем возможен переход на прием препарата внутрь."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСосудистая патология глазного дна и дистрофия сетчатки\u003c/i\u003e (в комплексной терапии): парабульбарно по 0,5 мл раствора для инъекций в течение 10 дней."}},{"type":"paragraph","data":{"text":"\u003ci\u003eФизические и умственные перегрузки:\u003c/i\u003e в/в по 0,5 г (5 мл раствора для инъекций) 1 раз в сутки; курс лечения — 10-14 дней. При необходимости курс повторяют через 2-3 недели."}},{"type":"paragraph","data":{"text":"\u003ci\u003eАбстинентный алкогольный синдром: \u003c/i\u003eв/в по 500 мг (5 мл раствора для инъекций) 2 раза в сутки; курс лечения — 7-10 дней."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Редко — аллергические реакции (покраснение, кожная сыпь, зуд, отек), диспепсия, тахикардия, снижение или повышение артериального давления, возбуждение."}},{"type":"paragraph","data":{"text":"Очень редко — эозинофилия, общая слабость."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптомы: снижение артериального давления, головная боль, тахикардия, головокружение, общая слабость."}},{"type":"paragraph","data":{"text":"Лечение: симптоматическое."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Усиливает действие коронародилатирующих и гипотензивных лекарственных препаратов, сердечных гликозидов. Ввиду возможного развития умеренной тахикардии и артериальной гипотензии, следует соблюдать осторожность при комбинации с нитроглицерином, нифедипином, альфа-адреноблокаторами, гипотензивными лекарственными средствами и периферическими вазодилататорами."}},{"type":"paragraph","data":{"text":"Можно сочетать с антиангинальными лекарственными средствами, антикоагулянтами, антиагрегантами, антиаритмическими препаратами, диуретиками, бронхолитиками."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"С осторожностью следует применять препарат при заболеваниях печени и/или почек, особенно в течение длительного времени."}},{"type":"paragraph","data":{"text":"Многолетний опыт лечения острого инфаркта миокарда и нестабильной стенокардии в кардиологических отделениях показывает, что мельдоний не является препаратом I ряда при остром коронарном синдроме и его применение не является остро необходимым."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВлияние на способность управлять транспортными средствами и обслуживать другие механизмы\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Нет данных о неблагоприятном воздействии мельдония на скорость психомоторных реакции."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Нет данных о неблагоприятном воздействии мельдония на скорость психомоторных реакции."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Раствор для инъекций 100 мг/мл. По 5 мл в ампулы нейтрального стекла."}},{"type":"paragraph","data":{"text":"По 5 ампул в контурную ячейковую упаковку из пленки поливинилхлоридной или из пленки поливинилхлоридной и фольги алюминиевой печатной лакированной."}},{"type":"paragraph","data":{"text":"По 1, 2 контурных ячейковых упаковки вместе с инструкцией по применению и ножом для вскрытия ампул (в случае использования ампул с точкой или кольцом облома нож не вкладывают) помещают в пачку из картона."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре не выше 25°С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"4 года. Не использовать после истечения срока годности, указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают по рецепту."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ФГУП «Московский эндокринный завод», Россия"}},{"type":"paragraph","data":{"text":"109052, г. Москва, ул. Новохохловская, д. 25"}},{"type":"paragraph","data":{"text":"Адрес места производства:"}},{"type":"paragraph","data":{"text":"г. Москва, ул. Новохохловская, д. 25, стр. 1, стр. 2"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"\n\nАО «Нижфарм», Россия"}},{"type":"paragraph","data":{"text":"603950, г. Нижний Новгород,"}},{"type":"paragraph","data":{"text":"ул. Салганская, д. 7"}},{"type":"paragraph","data":{"text":"Тел.: (831) 278-80-88"}},{"type":"paragraph","data":{"text":"Факс: (831) 430-72-28"}},{"type":"paragraph","data":{"text":"E-mail: \u003ca href=\"mailto:med@stada.ru\"\u003emed@stada.ru\u003c/a\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"Структурный аналог гамма-бутиробетаина. Мельдоний ингибирует гамма-бутиробетаингидроксилазу, что приводит к снижению синтеза карнитина, ограничению транспорта в клетки длинноцепочечных жирных кислот и препятствует накоплению активированных форм неокисленных жирных кислот — производных ацилкарнитина и ацилкофермента А. В условиях ишемии восстанавливает равновесие процессов доставки и потребления кислорода, активирует гликолиз; предупреждает нарушение транспорта и снижение уровня аденозинтрифосфата (АТФ). В результате снижения концентрации карнитина усиленно синтезируется гамма-бутиробетаин, обладающий вазодилатирующими свойствами. В случае острого ишемического повреждения миокарда замедляет образование некротической зоны, укорачивает реабилитационный период. При хронической сердечной недостаточности (ХСН) повышает толерантность к физической нагрузке. При стенокардии напряжения снижает частоту приступов. При острых и хронических ишемических нарушениях мозгового кровообращения улучшает циркуляцию крови в очаге ишемии, способствует перераспределению крови в пользу ишемизированного участка. Эффективен в случае сосудистой и дистрофической патологии глазного дна. Оказывает тонизирующее действие на центральную нервную систему, способствует устранению функциональных нарушений соматического и вегетативного отделов нервной системы у больных хроническим алкоголизмом в период абстиненции. Уменьшает выраженность симптомов психического и физического перенапряжения. После внутривенного введения максимальная концентрация препарата в плазме крови достигается сразу после его введения. Данных о биодоступности препарата после внутримышечного введения нет. Метаболизируется в организме с образованием двух основных метаболитов, которые выводятся почками. Период полувыведения составляет 3-6 часов.","substance":[{"id":726,"title":"Мельдоний","title_latin":"Meldonium","slug":"meldoniy_726"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Кардионат - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/71503/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/71503/share_default/"}},"diseases":[],"other_packages":[],"other_product_forms":[],"related_products":{"title":"Аналоги","type":"analogs","products":[{"id":95750,"title":"Мельдоний","subtitle":{"full":"Раствор, ампулы, 10 шт, 5 мл, 100 мг/мл, для инъекций","short":"Раствор, 10 шт, 5 мл, 100 мг/мл","package":"10 шт, 5 мл, 100 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