Гиперчувствительность аппендицит ректальное кровотечение кишечная непроходимость острые воспалительные заболевания желудочно-кишечного тракта дегидратация гипермагниемия беременность период грудного вскармливания детский возраст до 18 лет.
Инструкция
Регистрационный номер
ЛП-003463 от 16.02.16
Торговое название препарата
Магния сульфат
Лекарственная форма
порошок для приготовления раствора для приема внутрь
Состав
На одну упаковку:
Магния сульфат гептагидрат - 25 г
Описание
Белый или почти белый кристаллический порошок, или бесцветные призматические кристаллы
Фармакотерапевтическая группа
Слабительное средство
Фармакологические свойства
Фармакодинамика:
При приеме внутрь действует как слабительное средство (в связи с плохой всасываемостью препарата в кишечнике в нем создается высокое осмотическое давление происходит накопление воды в кишечнике содержимое кишечника разжижается перистальтика усиливается). Обладает желчегонным действием. Является антидотом при отравлениях солями тяжелых металлов (образует нерастворимые сульфатные комплексы тяжелых металлов и благодаря слабительному действию выводит их из организма).
Фармакокинетика:
При пероральном приеме плохо всасывается (не более 20%) в тощей и подвздошной кишке подвергается реабсорбции из желчи панкреатического и кишечного сока. При синдроме мальабсорбции и употреблении пищи богатой жирами абсорбция ионов магния снижается. Связь с внутриклеточными белками и макроэргическими фосфатами - 30%. Время наступления максимальной концентрации в плазме крови - 4 часа. Ионы магния депонируются в костях скелетной мускулатуре почках печени и миокарде; в небольших количествах в тканевой жидкости и эритроцитах. Проникает через гематоэнцефалический и плацентарный барьер создает в материнском молоке концентрации в два раза превышающие таковые плазме. Выведение осуществляется почками и с калом.
Показания к применению
Запоры очищение кишечника перед диагностическими манипуляциями.
Гиперчувствительность аппендицит ректальное кровотечение кишечная непроходимость острые воспалительные заболевания желудочно-кишечного тракта дегидратация гипермагниемия беременность период грудного вскармливания детский возраст до 18 лет.
Применение при беременности и в период грудного вскармливания
Противопоказано применение магния сульфата внутрь при беременности. Парентеральное применение при беременности возможно только по назначению врача, если предполагаемая польза для матери превышает потенциальный риск для плода; противопоказано применение в предродовой период (за 2 часа до родов).
При необходимости применения в период лактации грудное вскармливание следует прекратить.
Способ применения и дозы
Принимают внутрь.
Взрослые - по 20-25 г 1 раз в сутки натощак предварительно растворив препарат в стакане воды (200 мл).
Возможно применение препарата в виде клизм (50-100 мл 20-30% раствора).
При отравлении солями тяжелых металлов промывают желудок 1% раствором магния сульфата или дают внутрь 20 г растворив в стакане воды (200 мл). Для промывания желудка больному дают выпить 1% раствор магния сульфата (20 г на 2 литра воды). Если рвота быстро не наступает то ее вызывают механическим воздействием на корень языка. Промывание проводят до прозрачных промывных вод.
Побочное действие
Тошнота рвота диарея обострение воспалительных заболеваний желудочно-кишечного тракта метеоризм боль в животе спастического характера жажда нарушение электролитного баланса (повышенная утомляемость астения спутанное сознание аритмия судороги) гипермагниемия при наличии почечной недостаточности (ранние признаки гипермагниемии: брадикардия диплопия внезапный "прилив" крови к коже лица головная боль головокружение снижение артериального давления тошнота одышка смазанная речь рвота слабость).
В случае возникновения вышеперечисленных побочных реакций или побочных реакций не указанных в данной инструкции по медицинскому применению лекарственного средства необходимо обратиться к врачу.
Передозировка
Симптомы: тяжелая диарея.
При подозрении на передозировку необходимо обратиться к врачу.
Лечение: симптоматическое. В качестве антидота вводят внутривенно (медленно) препараты кальция (кальция хлорид и кальция глюконат) перитонеальный диада или гемодиализ симптоматические средства (корригирующие функции сердечно сосудистой системы).
Взаимодействие с другими лекарственными средствами
Снижает эффект пероральных антикоагулянтов (в т.ч. кумариновых производных или дериватов индандиона) сердечных гликозидов фенотиазинов (особенно хлорпромазина).
Снижает абсорбцию ципрофлоксацина этидроновой кислоты антибиотиков группы тетрациклина (образует неабсорбированные комплексы с пероральными тетрациклинами) ослабляет действие стрептомицина и тобрамицина (слабительные магнийсодержащие лекарственные препараты следует принимать через 1-2 ч после применения вышеуказанных лекарственных средств).
Фармацевтически несовместим (образуется осадок) с препаратами кальция этанолом (в высоких концентрациях) карбонатами гидрокарбонатами и фосфатами щелочных металлов солями мышьяковой кислоты бария стронция клиндамицина фосфатом гидрокортизона натрия сукцинатом полимиксина В сульфатом прокаина гидрохлоридом салицилатами и тартратами.
Особые указания
Препарат следует принимать эпизодически (не регулярно при возникновении ситуаций указанных в разделе "Показания к применению") систематическое применение не рекомендуется. Если после приема лекарственного средства нет дефекации необходимо обратиться к врачу.
При сердечной и почечной недостаточности расстройстве пищевого поведения (анорексия или булемия) при приеме слабительного в течение недели необходимо проконсультироваться с врачом.
Влияние на способность управлять автомобилем и движущимися механизмами
В период лечения пациенты должны воздержаться от управления транспортными средствами и занятий другими потенциально опасными видами деятельности требующими повышенной концентрации внимания и быстроты психомоторных реакций (риск развития диплопии головокружения головной боли).
Форма выпуска
Порошок для приготовления раствора для приема внутрь.
Условия хранения
В защищенном от света месте при температуре не выше 25 °С.
Хранить в недоступном для детей месте.
Срок годности
5 лет.
Не использовать позже даты указанной на упаковке
Условия отпуска
Без рецепта
Производитель
Общество с ограниченной ответственностью "ЮжФарм" (ООО "ЮжФарм")
Организация, принимающая претензии потребителей
ООО "ЮжФарм"
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
Начните сравнивать цены и заказывать лекарства прямо в приложении
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Обладает желчегонным действием. Является антидотом при отравлениях солями тяжелых металлов (образует нерастворимые сульфатные комплексы тяжелых металлов и благодаря слабительному действию выводит их из организма)."}},{"type":"header","data":{"text":"Фармакокинетика:","level":3}},{"type":"paragraph","data":{"text":"При пероральном приеме плохо всасывается (не более 20%) в тощей и подвздошной кишке подвергается реабсорбции из желчи панкреатического и кишечного сока. При синдроме мальабсорбции и употреблении пищи богатой жирами абсорбция ионов магния снижается. Связь с внутриклеточными белками и макроэргическими фосфатами - 30%. Время наступления максимальной концентрации в плазме крови - 4 часа. Ионы магния депонируются в костях скелетной мускулатуре почках печени и миокарде; в небольших количествах в тканевой жидкости и эритроцитах. Проникает через гематоэнцефалический и плацентарный барьер создает в материнском молоке концентрации в два раза превышающие таковые плазме. Выведение осуществляется почками и с калом."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Запоры очищение кишечника перед диагностическими манипуляциями."}},{"type":"paragraph","data":{"text":"Отравление солями тяжелых металлов (ртуть мышьяк тетраэтилсвинец барий)."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Гиперчувствительность аппендицит ректальное кровотечение кишечная непроходимость острые воспалительные заболевания желудочно-кишечного тракта дегидратация гипермагниемия беременность период грудного вскармливания детский возраст до 18 лет."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"Блокада сердца сердечная недостаточность хроническая почечная недостаточность."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Противопоказано применение магния сульфата внутрь при беременности. Парентеральное применение при беременности возможно только по назначению врача, если предполагаемая польза для матери превышает потенциальный риск для плода; противопоказано применение в предродовой период (за 2 часа до родов)."}},{"type":"paragraph","data":{"text":"При необходимости применения в период лактации грудное вскармливание следует прекратить."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Принимают внутрь."}},{"type":"paragraph","data":{"text":"Взрослые - по 20-25 г 1 раз в сутки натощак предварительно растворив препарат в стакане воды (200 мл)."}},{"type":"paragraph","data":{"text":"Возможно применение препарата в виде клизм (50-100 мл 20-30% раствора)."}},{"type":"paragraph","data":{"text":"При отравлении солями тяжелых металлов промывают желудок 1% раствором магния сульфата или дают внутрь 20 г растворив в стакане воды (200 мл). Для промывания желудка больному дают выпить 1% раствор магния сульфата (20 г на 2 литра воды). Если рвота быстро не наступает то ее вызывают механическим воздействием на корень языка. Промывание проводят до прозрачных промывных вод."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Тошнота рвота диарея обострение воспалительных заболеваний желудочно-кишечного тракта метеоризм боль в животе спастического характера жажда нарушение электролитного баланса (повышенная утомляемость астения спутанное сознание аритмия судороги) гипермагниемия при наличии почечной недостаточности (ранние признаки гипермагниемии: брадикардия диплопия внезапный \"прилив\" крови к коже лица головная боль головокружение снижение артериального давления тошнота одышка смазанная речь рвота слабость)."}},{"type":"paragraph","data":{"text":"В случае возникновения вышеперечисленных побочных реакций или побочных реакций не указанных в данной инструкции по медицинскому применению лекарственного средства необходимо обратиться к врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Симптомы: тяжелая диарея."}},{"type":"paragraph","data":{"text":"При подозрении на передозировку необходимо обратиться к врачу."}},{"type":"paragraph","data":{"text":"Лечение: симптоматическое. В качестве антидота вводят внутривенно (медленно) препараты кальция (кальция хлорид и кальция глюконат) перитонеальный диада или гемодиализ симптоматические средства (корригирующие функции сердечно сосудистой системы)."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Снижает эффект пероральных антикоагулянтов (в т.ч. кумариновых производных или дериватов индандиона) сердечных гликозидов фенотиазинов (особенно хлорпромазина)."}},{"type":"paragraph","data":{"text":"Снижает абсорбцию ципрофлоксацина этидроновой кислоты антибиотиков группы тетрациклина (образует неабсорбированные комплексы с пероральными тетрациклинами) ослабляет действие стрептомицина и тобрамицина (слабительные магнийсодержащие лекарственные препараты следует принимать через 1-2 ч после применения вышеуказанных лекарственных средств)."}},{"type":"paragraph","data":{"text":"Фармацевтически несовместим (образуется осадок) с препаратами кальция этанолом (в высоких концентрациях) карбонатами гидрокарбонатами и фосфатами щелочных металлов солями мышьяковой кислоты бария стронция клиндамицина фосфатом гидрокортизона натрия сукцинатом полимиксина В сульфатом прокаина гидрохлоридом салицилатами и тартратами."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат следует принимать эпизодически (не регулярно при возникновении ситуаций указанных в разделе \"Показания к применению\") систематическое применение не рекомендуется. Если после приема лекарственного средства нет дефекации необходимо обратиться к врачу."}},{"type":"paragraph","data":{"text":"При сердечной и почечной недостаточности расстройстве пищевого поведения (анорексия или булемия) при приеме слабительного в течение недели необходимо проконсультироваться с врачом."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"В период лечения пациенты должны воздержаться от управления транспортными средствами и занятий другими потенциально опасными видами деятельности требующими повышенной концентрации внимания и быстроты психомоторных реакций (риск развития диплопии головокружения головной боли)."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Порошок для приготовления раствора для приема внутрь."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В защищенном от света месте при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"5 лет."}},{"type":"paragraph","data":{"text":"Не использовать позже даты указанной на упаковке"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Общество с ограниченной ответственностью \"ЮжФарм\" (ООО \"ЮжФарм\")"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО \"ЮжФарм\""}}]}],"source":null},"description_toggle":false,"short_description":"При приеме внутрь действует как слабительное средство (в связи с плохой всасываемостью препарата в кишечнике в нем создается высокое осмотическое давление происходит накопление воды в кишечнике содержимое кишечника разжижается перистальтика усиливается). 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