Сосудосуживающий препарат для местного применения в лор-прак... Инструкция
Показания к применению
Острый ринит вирусного или бактериального генеза; - аллергический ринит; - острый синусит; - хронический синусит в фазе обострения; - поллиноз; - средний отит (с целью уменьшения отека слизистой оболочки носоглотки и восстановления проходимости евстахиевой трубы).
Противопоказания
Повышенная чувствительность к компонентам препарата; - атрофический ринит; - закрытоугольная глаукома; - артериальная гипертензия; - выраженный атеросклероз; - тахикардия; - гипертиреоз (для капель назальных); - хирургическое вмешательство на мозговых оболочках (в анамнезе); - одновременный прием ингибиторов МАО и период 14 дней после окончания их применения; ...
Действующее вещество: Ксилометазолин (Xylometazoline)Концентрация действующего вещества (%): 0, 05
Фармакологические свойства
Сосудосуживающий препарат для местного применения в лор-практике. альфа-адреномиметик из группы производных имидазола. в низких концентрациях действует на α2-адренорецепторы, в высоких концентрациях оказывает действие на α1-адренорецепторы.при местном применении вызывает сужение кровеносных сосудов, что приводит к уменьшению отека и гиперемии слизистых оболочек носоглотки, уменьшает количество выделений из носа, облегчает носовое дыхание при ринитах.действие препарата начинается через 5-10 мин и сохраняется в течение 5-6 ч при применении в форме капель назальных и в течение 10 ч при применении в форме геля назального.
Показания к применению
Острый ринит вирусного или бактериального генеза; - аллергический ринит; - острый синусит; - хронический синусит в фазе обострения; - поллиноз; - средний отит (с целью уменьшения отека слизистой оболочки носоглотки и восстановления проходимости евстахиевой трубы).
Противопоказания
Повышенная чувствительность к компонентам препарата; - атрофический ринит; - закрытоугольная глаукома; - артериальная гипертензия; - выраженный атеросклероз; - тахикардия; - гипертиреоз (для капель назальных); - хирургическое вмешательство на мозговых оболочках (в анамнезе); - одновременный прием ингибиторов МАО и период 14 дней после окончания их применения; - одновременный прием трициклических антидепрессантов; - беременность; - детский возраст до 6 лет (для 0.1% капель назальных) и до 2 лет (для 0.05% капель назальных)
Применение при беременности и в период грудного вскармливания
Противопоказан при беременности. Данных о выделении ксилометазолина с грудным молоком не имеется. Необходимо с осторожностью назначать препарат женщинам в период лактации (грудного вскармливания).
Способ применения и дозы
Галазолин в форме капель 0.05% назначают детям в возрасте от 2 до 6 лет по 1-2 капли в каждую ноздрю 1-2 раза/сут. Не следует превышать указанные дозы. Курс лечения составляет не более 3-5 дней. Максимальная длительность применения - 2 недели.
Побочное действие
Местные реакции: при частом и/или длительном применении - раздражение и/или сухость слизистой оболочки носоглотки, жжение и парестезия слизистой оболочки полости носа, чиханье, гиперсекреция слизистой оболочки полости носа; редко - отек слизистой оболочки полости носа. Системные реакции: редко - сердцебиение, тахикардия, пальпитация, аритмия, повышение АД (особенно у пациентов с заболеваниями сердечно-сосудистой системы), головная боль, тошнота, рвота, бессонница, слабость, усталость, сонливости, нарушение зрения, аллергические реакции (удушье, вазомоторный отек); при длительном применении и/или при применении в высоких дозах - депрессия, медикаментозный ринит.
Передозировка
Не отмечены случаи передозировки у взрослых. В случае применения слишком большой дозы или неправильного применения может наступить заглатывание капель и всасывание действующего вещества из ЖКТ. Это происходит, в основном, у детей. В этом случае наблюдается выраженный седативный эффект. Симптомы: при случайном проглатывании препарата (чаще у детей) отмечается тахикардия, аритмия, повышение АД, сонливость, спутанность сознания, угнетение дыхания или нерегулярное дыхание. Лечение: проводят симптоматическую терапию.
Особые указания
Перед применением необходимо очистить носовые ходы. Галазолин как и другие симпатомиметики, с особой осторожностью следует применять у пациентов с гиперчувствительностью к адреномиметикам, проявляющейся бессонницей, головокружением, тремором, нарушением сердечного ритма и повышением АД. Не следует применять препарат у пациентов с хроническим или вазомоторным ринитом, поскольку у них отмечается тенденция к применению препарата дольше 5 дней. Продолжительное применение лекарственного препарата (более 2 недель) может привести к вторичному расширению кровеносных сосудов и впоследствии к вторичному медикаментозному риниту. Причиной данного заболевания является угнетение высвобождения норадреналина из нервных окончаний посредством возбуждения пресинаптических α2-рецепторов. Не следует превышать рекомендуемые дозы, особенно у детей и пациентов пожилого возраста. Препарат содержит бензалкония хлорид, поэтому может вызывать раздражение слизистой оболочки носа. Влияние на способность к вождению автотранспорта и управлению механизмамиПрепарат не влияет на способность к управлению транспортными средствами и обслуживанию движущихся механизмов, если применяется в рекомендуемой дозе и в течение непродолжительного времени. При длительном применении или применении в высоких дозах возможно появление нежелательных эффектов со стороны сердечно-сосудистой системы и ЦНС. В случае развития побочных эффектов препарат может оказывать влияние на способность к управлению транспортными средствами и механизмами.
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