Куросурф Суспензия, флакон, 1 шт, 80 мг/1 мл, фл. 1.5 мл 1 шт.

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В случае невозможности удаления обструкции эндотрахеальнуто трубку необходимо немедленно заменить."}},{"type":"paragraph","data":{"text":"Не рекомендуется проводить аспирацию трахеобронхиального секрета в течение, по крайней мере, 6 часов после введения препарата, за исключением условий, угрожающих жизни."}},{"type":"paragraph","data":{"text":"В случае возникновения брадикардии, артериальной гипотензии и понижения насыщаемости крови кислородом введение препарата необходимо приостановить и провести необходимые меры по нормализации ЧСС, после чего лечение может быть продолжено."}},{"type":"paragraph","data":{"text":"Дети, рожденные после длительного безводного периода (более 3 недель), могут плохо реагировать на заместительную терапию препаратом, что может быть связано с гипоплазией легких."}},{"type":"paragraph","data":{"text":"Можно ожидать, что введение препарата снизит тяжесть РДС или риск его возникновения, однако нельзя предполагать, что терапия полностью устранит смертность и заболеваемость, связанные с преждевременными родами, поскольку преждевременно рожденные дети могут подвергаться другим осложнениям вследствие их незрелости."}},{"type":"paragraph","data":{"text":"Применение препарата с целью профилактики необходимо проводить в соответствии со следующими рекомендациями:"}},{"type":"paragraph","data":{"text":"- недоношенные новорожденные с гестационным возрастом от 24 до 25 недель: профилактика рекомендуется;"}},{"type":"paragraph","data":{"text":"- недоношенные новорожденные с гестационным возрастом от 26 до 28 недель: рекомендуется профилактика в случае отсутствия антенатального применения кортикостероидных препаратов."}},{"type":"paragraph","data":{"text":"Принимая во внимание факторы риска у недоношенных новорожденных с гестационным возрастом менее 28 недель, профилактика также рекомендуется при наличии следующих факторов риска развития РДС: перинатальная асфиксия, необходимость интубации при рождении, наличие сахарного диабета уматери, мужской пол ребенка, семейная предрасположенность к РДС, кесарево сечение."}},{"type":"paragraph","data":{"text":"- недоношенные новорожденные с гестационным возрастом от 29 недель и более: препарат должен вводиться только в случае развития РДС."}},{"type":"paragraph","data":{"text":"Восстановление газообмена в альвеолах может привести к быстрому увеличению концентрации кислорода в артериальном русле, что потребует немедленной перестройки показателей ИВЛ для того, чтобы избежать гипероксии. В связи с этим рекомендуется проводить продолжительный мониторинг газового состава артериальной крови и тканевого содержания кислорода."}},{"type":"paragraph","data":{"text":"Подогретые перед употреблением флаконы не следует помещать обратно в холодильник. Не используйте оставшийся во флаконе препарат вторично.\n\n"}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nСуспензия для эндотрахеального введения 80 мг/мл."}},{"type":"paragraph","data":{"text":"По 1,5 мл или 3 мл препарата во флакон из бесцветного стекла, закрытый пробкой из хлорбутила, обжатый алюминиевым колпачком и закрытый пластиковой крышкой. Один или два флакона в футляре из пенопласта вместе с инструкцией по применению помещают в картонную пачку.\n\n"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В темном месте при температуре от 2 до 8 °С. Список Б. 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