Прохэнс Раствор, флакон, 1 шт, 20 мл, 279,3 мг/мл, для внутривенного введения

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Доза не должна превышать 0.1 ммоль/кг, в ходе одного исследования не рекомендуется использование более 1 дозы. Повторное введение возможно только более чем через 7 дней."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны иммунной системы: \u003c/i\u003eнечасто - анафилактические/анафилактоидные реакции."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны психики:\u003c/i\u003e редко - тревога."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны нервной системы:\u003c/i\u003e нечасто - головная боль, парестезии, головокружение, изменение вкуса; редко - снижение умственных способностей, эпилептиформные судороги, нарушение координации; неизвестно - потеря сознания, вазо-вагальные реакции."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны органа зрения: \u003c/i\u003eнечасто - повышенное слезоотделение."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны органа слуха и лабиринтные нарушения:\u003c/i\u003e редко - шум в ушах."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны сердечно-сосудистой системы:\u003c/i\u003e нечасто - снижение АД, ощущение \"приливов\" к лицу; редко - тахикардия; неизвестно - увеличение интервала R-R."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны дыхательной системы:\u003c/i\u003e редко - ларингоспазм, свистящее дыхание, одышка, ринит, кашель, боль в грудной клетке; неизвестно - отек легких, остановка дыхания."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны пищеварительной системы:\u003c/i\u003e часто - тошнота; нечасто - сухость во рту, рвота; редко - боль в животе, отечность и/или зуд языка, гингивит, диарея, повышенное слюноотделение, затрудненное глотание."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны кожи и подкожных тканей:\u003c/i\u003e нечасто - зуд, кожные высыпания, повышенное потоотделение."}},{"type":"paragraph","data":{"text":"\u003ci\u003eАллергические реакции:\u003c/i\u003e нечасто - крапивница; редко - отек лица."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны костно-мышечной системы:\u003c/i\u003e редко - мышечная скованность."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны мочевыделительной системы:\u003c/i\u003e неизвестно - острая почечная недостаточность."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОбщие реакции:\u003c/i\u003e часто - боль в месте введения, астения; редко - гипертермия."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"С осторожностью: детский возраст от 6 месяцев до 2 лет по всем показаниям, кроме МРТ всего тела; в связи с тем, что гадотеридол выводится из организма почками, с осторожностью следует применять у пациентов с нарушениями функции почек (СКФ<30 мл/мин/1.73 м\u003csup\u003e2\u003c/sup\u003e); у пациентов с острой почечной недостаточностью на фоне гепаторенального синдрома; у пациентов в периоперационный период пересадки печени; у пациентов с эпилепсией; у пациентов с сердечно-сосудистыми заболеваниями; пациентов с нарушениями кровообращения, с нарушениями со стороны ЦНС; у пациентов с аллергическими заболеваниями в анамнезе."}},{"type":"paragraph","data":{"text":"Гадотеридол может быть использовать только специалистами, имеющими клинический опыт проведения МРТ."}},{"type":"paragraph","data":{"text":"При применении препаратов, содержащих гадолиний, необходимо учитывать возможность накопления действующего вещества в головном мозге и других органах, в связи с чем, они должны использоваться только в случаях крайней необходимости, при невозможности проведения альтернативных методов диагностики и в минимально возможных дозах, позволяющих получить необходимое изображение."}},{"type":"paragraph","data":{"text":"Имеются данные о нефрогенном системном фиброзе, ассоциированном с приемом гадолинийсодержащих контрастных агентов у пациентов с нарушениями функции почек тяжелой степени (СКФ < 30 мл/мин/1.73 м\u003csup\u003e2\u003c/sup\u003e). У пациентов, находящихся на гемодиализе, его можно кратковременно применять для выведения гадотеридола из организма. Но для пациентов, которые до этого не подвергались гемодиализу, необоснованно начинать его проведение для предупреждения или лечения нефрогенного системного фиброза."}},{"type":"paragraph","data":{"text":"В виду того, что после введения гадотеридола были зарегистрированы анафилактические реакции, следует обратить особое внимание на наличие лекарственных препаратов и соответствующего инструментария для неотложных мероприятий. Риск развития реакций гиперчувствительности выше в случаях: предшествующей реакции на контрастное средство; при бронхиальной астме; - аллергических заболеваниях в анамнезе (бронхиальная астма, сенная лихорадка). Большинство этих реакций развиваются в течение 0.5-1 ч после введения. Однако в редких случаях могут развиваться отсроченные реакции."}},{"type":"paragraph","data":{"text":"Следует учитывать, что пациенты, принимающие бета-адреноблокаторы, могут быть резистентны к лечению реакций гиперчувствительности препаратами, обладающими бета-агонистическим действием."}},{"type":"paragraph","data":{"text":"У пациентов с предрасположенностью к развитию аллергических реакций решение о применении гадотеридола следует принимать только после тщательной оценки соотношения риск/польза."}},{"type":"paragraph","data":{"text":"После проведения диагностической процедуры с использованием гадотеридола рекомендуется наблюдение за состоянием пациента."}},{"type":"paragraph","data":{"text":"Не следует проводить МРТ с контрастными веществами, содержащими другие хелатные комплексы гадолиния в течение 7 часов после применения гадотеридола."}},{"type":"paragraph","data":{"text":"При введении контрастного средства у пациентов с эпилепсией, поражением ЦНС или судорогами в анамнезе может наблюдаться снижение порога судорожной активности. Необходим контроль за состоянием пациента."}},{"type":"paragraph","data":{"text":"В распоряжении врача должен иметься лекарственные средства, необходимые для быстрого купирования судорог."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВлияние на способность к управлению транспортными средствами и механизмами\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Учитывая вероятность побочных реакций в виде головокружения, следует избегать подобных видов деятельности в течение 24 ч после введения гадотеридола."}}]}],"source":null},"description_toggle":false,"short_description":"Диагностическое средство. Неионогенное парамагнитное контрастное вещество для магнитно-резонансной томографии (МРТ). При локализации в магнитном поле гадотеридол сокращает время продольной (Т1) релаксации протонов воды в тканях исследуемых областей. В рекомендуемых дозах эффект наблюдается с наибольшей чувствительностью в Т1- взвешенной последовательности снимков Гадотеридол не проникает через интактный ГЭБ, и, таким образом, не кумулирует в неповрежденном головном мозге или патологических очагах с неповрежденным ГЭБ, таких как кисты, сформировавшиеся послеоперационные рубцы и т.д. Однако повреждение ГЭБ или нормальная васкуляризация позволяют гадотеридолу проникать в такие патологические очаги, как новообразования, абсцессы и подострые инфаркты.","substance":[],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Прохэнс - фото упаковки","image_share":{"isTouch":{"default":null},"isFromTablet":{"default":null}},"diseases":[],"other_packages":[],"other_product_forms":[],"related_products":{"title":"Похожие товары","type":"nondrugs","products":[{"id":107188,"title":"Примовист","subtitle":{"full":"Раствор, 10 мл","short":"Раствор, 10 мл","package":"10 мл"},"prescription":true,"catalog_section_id":44,"manufacturer":{"id":2666,"title":"Schering Plough","slug":"shering_plau_2666","logo":{"isTouch":{"retina":null,"default":null},"isFromTablet":{"retina":null,"default":null}}},"is_advert":false,"product_form":"Раствор","slug":"107188-primovist","attributes":{"count":"","dose":"","volume":"10 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