Олитид Таблетки, банка, 30 шт, 600 мг, для приема внутрь

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У детей, чьи матери принимали НИОТ (нуклеозидные ингибиторы обратной транскриптазы) во время беременности, польза защиты от ВИЧ-инфекции превышала риск от возникновения нежелательных реакций."}},{"type":"paragraph","data":{"text":"Грудное вскармливание"}},{"type":"paragraph","data":{"text":"ВИЧ-инфицированным женщинам не следует кормить детей грудью, поскольку ВИЧ- инфекция может передаться ребенку вместе с грудным молоком."}},{"type":"paragraph","data":{"text":"Небольшое количество компонентов, входящих в состав препарата Олитид, также может проникать в грудное молоко."}},{"type":"paragraph","data":{"text":"Если Вы кормите грудью или планируете кормить грудью, немедленно сообщите Вашему лечащему врачу."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Всегда принимайте препарат в полном соответствии с рекомендациями лечащего врача. При появлении сомнений посоветуйтесь с лечащим врачом."}},{"type":"paragraph","data":{"text":"Рекомендуемая доза:"}},{"type":"paragraph","data":{"text":"Рекомендуемая суточная доза для взрослых и детей с массой тела более 25 кг составляет 600 мг. Препарат принимают в дозе 300 мг 2 раза в сутки или 600 мг 1 раз в сутки."}},{"type":"paragraph","data":{"text":"Применение у детей"}},{"type":"paragraph","data":{"text":"Не давайте препарат детям с массой тела менее 14 кг, потому что им невозможно подобрать дозу абакавира в таблетках."}},{"type":"paragraph","data":{"text":"Дети с массой тела от 14 кг до 20 кг: рекомендуемая суточная доза составляет 300 мг в сутки: 150 мг 2 раза в сутки или 300 мг 1 раз в сутки."}},{"type":"paragraph","data":{"text":"Дети с массой тела от 20 кг до 25 кг: рекомендуемая доза составляет 450 мг в сутки: 150 мг утром и 300 мг вечером или 450 мг 1 раз в сутки."}},{"type":"paragraph","data":{"text":"Детям с массой тела более 25 кг препарат Олитид назначают в таких же дозах, как взрослым."}},{"type":"paragraph","data":{"text":"Путь и (или) способ введения"}},{"type":"paragraph","data":{"text":"Препарат Олитид принимают внутрь, независимо от приема пищи."}},{"type":"paragraph","data":{"text":"Таблетки рекомендуется проглатывать полностью, не разжевывая, не разламывая и не измельчая."}},{"type":"paragraph","data":{"text":"При переходе от режима приема 2 раза в сутки к режиму приема 1 раз в сутки следует принять первую рекомендуемую однократную дозу (как описано выше) примерно через 12 ч после последней принятой дозы по режиму двукратного приема, а затем продолжать принимать рекомендуемую однократную дозу (как описано выше) примерно каждые 24 ч."}},{"type":"paragraph","data":{"text":"При возврате к режиму приема 2 раза в сутки следует принять первую рекомендуемую дозу по режиму двукратного приема примерно через 24 ч после последней принятой однократной дозы."}},{"type":"paragraph","data":{"text":"Если Вам трудно глотать таблетки, врач может назначить Вам \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/9.html?XFrom=www.lsgeotar.ru\"\u003eабакавир\u003c/a\u003e в другой лекарственной форме или порекомендует Вам измельчать таблетки и добавлять их к небольшому количеству мягкой пищи или жидкости. Всю полученную смесь необходимо принять внутрь незамедлительно."}},{"type":"paragraph","data":{"text":"Если Вы забыли принять препарат Олитид"}},{"type":"paragraph","data":{"text":"Если Вы забыли принять очередную таблетку препарата Олитид, примите ее как можно скорее, как только вспомните об этом. Не принимайте двойную дозу, чтобы компенсировать пропущенную дозу."}},{"type":"paragraph","data":{"text":"Важно не забывать принимать препарат, потому что при нерегулярном приеме эффективность лечения снижается."}},{"type":"paragraph","data":{"text":"При наличии вопросов по применению препарата обратитесь к лечащему врачу."}},{"type":"paragraph","data":{"text":"Если Вы прекратили прием препарата Олитид"}},{"type":"paragraph","data":{"text":"Если Вы прекратили прием препарата Олитид по какой-либо причине - особенно, в случае, если у Вас возникли подозрения о развитии побочных эффектов или другого заболевания:"}},{"type":"paragraph","data":{"text":"Обратитесь к Вашему лечащему врачу, прежде чем снова начать прием препарата. Ваш врач оценит, были ли эти симптомы связаны с реакцией повышенной чувствительности (гиперчувствительности). Если врач сочтет, что они могли быть связаны, Вам скажут никогда больше не принимать препарат Олитид или любое другое лекарство, содержащее \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/9.html?XFrom=www.lsgeotar.ru\"\u003eабакавир\u003c/a\u003e. Важно, чтобы Вы последовали этому совету."}},{"type":"paragraph","data":{"text":"Если Ваш врач сочтет, что Вам следует снова начать прием препарата, Вас могут попросить принять первые дозы препарата в месте, где у Вас будет свободный доступ к медицинской помощи, на случай если она Вам понадобится."}},{"type":"paragraph","data":{"text":"При наличии вопросов по применению препарата обратитесь к лечащему врачу."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Подобно всем лекарственным препаратам препарат может вызывать нежелательные реакции, однако они возникают не у всех."}},{"type":"paragraph","data":{"text":"В случае лечения ВИЧ-инфекции могут возникнуть трудности при определении того, является ли симптом нежелательной реакцией на препарат Олитид или другие лекарственные препараты, принимаемые Вами, или же это проявление самой ВИЧ-инфекции. В связи с этим крайне важно сообщать Вашему лечащему врачу о любых изменениях Вашего здоровья."}},{"type":"paragraph","data":{"text":"Наиболее серьезные возможные нежелательные реакции во время терапии препаратом Олитид — это реакции повышенной чувствительности (гиперчувствительности), то есть серьезные аллергические реакции."}},{"type":"paragraph","data":{"text":"У кого развиваются реакции повышенной чувствительности (гиперчувствительности)?"}},{"type":"paragraph","data":{"text":"У любого человека, принимающего препарат Олитид, может развиться реакция повышенной чувствительности, которая может стать угрожающей для жизни, если он продолжит принимать препарат Олитид."}},{"type":"paragraph","data":{"text":"Вероятность развития такой реакции выше, если Вы являетесь носителем гена, называемого HLA-B*5701 (однако у Вас может развиться такая реакция, даже если Вы не являетесь носителем этого гена). Вам следует провести исследование на выявление этого гена перед назначением препарата Олитид. Если Вы знаете, что являетесь носителем этого гена, сообщите об этом Вашему лечащему врачу."}},{"type":"paragraph","data":{"text":"Примерно у 3-4 пациентов из каждых 100, получавших \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/9.html?XFrom=www.lsgeotar.ru\"\u003eабакавир\u003c/a\u003e в клиническом исследовании, у которых отсутствовал ген HLA-B*5701, развивалась реакция повышенной чувствительности."}},{"type":"paragraph","data":{"text":"Каковы симптомы реакций повышенной чувствительности (гиперчувствительности)?"}},{"type":"paragraph","data":{"text":"Наиболее часто встречающимися симптомами являются:"}},{"type":"list","data":{"style":"ordered","items":["лихорадка (высокая температура) и сыпь на коже."]}},{"type":"paragraph","data":{"text":"Другими частыми симптомами являются:"}},{"type":"list","data":{"style":"ordered","items":["тошнота, рвота, диарея (понос), боль в животе (в желудке), выраженная усталость, чувство дискомфорта."]}},{"type":"paragraph","data":{"text":"Другие симптомы могут включать:"}},{"type":"list","data":{"style":"ordered","items":["боль в суставах или мышцах, припухлость в области шеи, одышку, боль в горле, кашель, периодические головные боли, воспаление глаз (конъюнктивит), изъязвления полости рта, низкое артериальное давление, покалывание или онемение кистей или стоп."]}},{"type":"paragraph","data":{"text":"Когда развиваются реакции повышенной чувствительности (гиперчувствительности)?"}},{"type":"paragraph","data":{"text":"Реакции повышенной чувствительности могут развиваться в любой момент во время проведения терапии препаратом Олитид, но с наибольшей вероятностью возникают в течение первых 6 недель лечения."}},{"type":"paragraph","data":{"text":"Если Вы заботитесь о ребенке, который получает лечение препаратом Олитид, Вам важно знать и понимать, что такое реакции гиперчувствительности. Если у ребенка появились симптомы, описанные ниже, крайне важно, чтобы Вы следовали приведенной инструкции."}},{"type":"paragraph","data":{"text":"Вы должны немедленно обратиться к врачу, если при приеме препарата у Вас появилась сыпь или 2 и более симптома из перечисленных групп:"}},{"type":"list","data":{"style":"ordered","items":["повышение температуры тела;","затрудненное дыхание, боль в горле или кашель;","тошнота или рвота, диарея, боль в животе;","сильное чувство усталости, боль в теле, недомогание."]}},{"type":"paragraph","data":{"text":"Ваш лечащий врач может сказать Вам, что Вы должны прекратить принимать препарат Олитид."}},{"type":"paragraph","data":{"text":"Если Вы раньше принимали препараты, содержащие \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/9.html?XFrom=www.lsgeotar.ru\"\u003eабакавир\u003c/a\u003e, обязательно скажите об этом Вашему лечащему врачу. Если Вы перестали их принимать из-за реакции гиперчувствительности, Вы никогда больше не должны принимать препарат Олитид и другие препараты, в состав которых входит абакавир. Если Вы все же примете препарат, у Вас может опасно снизиться артериальное давление, и Вы можете умереть."}},{"type":"paragraph","data":{"text":"Если Вы перестали принимать \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/9.html?XFrom=www.lsgeotar.ru\"\u003eабакавир\u003c/a\u003e по какой-то иной причине, Ваш врач, возможно, решит, что на всякий случай первые дозы препарата Олитид Вам нужно будет принять под его наблюдением, в условиях, когда Вам можно будет оказать срочную медицинскую помощь."}},{"type":"paragraph","data":{"text":"Ниже перечислены другие нежелательные реакции, которые наблюдались при применении препарата Олитид."}},{"type":"paragraph","data":{"text":"Часто —могут возникать не более чему 1 человека из 10:"}},{"type":"list","data":{"style":"ordered","items":["потеря аппетита,","головная боль;","тошнота;","рвота;","диарея;","сыпь;","высокая температура тела (лихорадка);","сонливость;","утомляемость."]}},{"type":"paragraph","data":{"text":"Редко — могут возникать не более чему 1 человека из 1000:"}},{"type":"list","data":{"style":"ordered","items":["воспаление поджелудочной железы (панкреатит)."]}},{"type":"paragraph","data":{"text":"Очень редко — могут возникать не более чему 1 человека из 10000:"}},{"type":"list","data":{"style":"ordered","items":["слабость, потеря аппетита, стремительная необъяснимая потеря веса, желудочно- кишечные нарушения (тошнота, рвота, боль в животе), нарушения со стороны дыхательной системы (учащенное или затрудненное дыхание) или неврологические нарушения (например, слабость мышц) - накопление молочной кислоты в крови (лактацидоз);","кожная сыпь с пузырями и элементами, похожими по форме на мишень (полиморфная экссудативная эритема);","распространенная сыпь с пузырями и отслойкой кожи, особенно вокруг рта, носа, глаз и на половых органах (синдром Стивенса-Джонсона) и более тяжелая форма, когда кожа отслаивается более чем на 30% поверхности тела (токсический эпидермальный некролиз)."]}},{"type":"paragraph","data":{"text":"Другие возможные нежелательные реакции комбинированной терапии ВИЧ-инфекции"}},{"type":"paragraph","data":{"text":"Комбинированная терапия, в частности, препаратом Олитид, может вызывать развитие иных симптомов во время лечения ВИЧ-инфекции."}},{"type":"paragraph","data":{"text":"Часто — могут возникать не более чему 1 человека из 10:"}},{"type":"list","data":{"style":"ordered","items":["сыпь (обычно в виде сочетания пятен и узелков (макулопапулезная) или зудящих волдырей (уртикарная));","тошнота;","рвота;","диарея;","боль в животе;","одышка;","кашель;","головная боль;","повышение биохимических показателей функции печени в крови;","боль в мышцах (миалгия);","лихорадка;","сонливость;","недомогание."]}},{"type":"paragraph","data":{"text":"Частота неизвестна:"}},{"type":"list","data":{"style":"ordered","items":["изъязвление слизистой оболочки рта;","боль в горле;","нарушение дыхания взрослых (респираторный дистресс-синдром взрослых);","дыхательная недостаточность;","ощущение жжения, покалывания, мурашек (парестезия);","снижение числа лимфоцитов в крови (лимфопения);","гепатит;","печеночная недостаточность;","миолиз;","боль в суставах (артралгия);","повышение активности креатинфосфокиназы в крови;","повышение концентрации креатинина;","почечная недостаточность;","отеки;","увеличение и болезненность лимфоузлов (лимфаденопатия);","снижение артериального давления;","воспаление глаз (конъюнктивит);","анафилактические реакции."]}},{"type":"paragraph","data":{"text":"Симптомы инфекции и воспаления"}},{"type":"paragraph","data":{"text":"У пациентов с поздней стадией ВИЧ-инфекции (СПИД) иммунная система ослаблена, и у них чаще развиваются серьезные инфекции (оппортунистические инфекции). Такие инфекции, возможно, были «скрытыми» и не обнаруживались до начала лечения в связи с ослабленной иммунной системой. После начала лечения иммунная система становится сильнее и может бороться с возбудителями, которые могут вызывать симптомы инфекции и воспаления."}},{"type":"paragraph","data":{"text":"Симптомы обычно включают высокую температуру тела (лихорадку) и дополнительно некоторые из следующих:"}},{"type":"list","data":{"style":"ordered","items":["головная боль;","боль в желудке;","затрудненное дыхание."]}},{"type":"paragraph","data":{"text":"В редких случаях, когда иммунная система становится сильнее, она может атаковать здоровые ткани тела (аутоиммунные расстройства). Симптомы аутоиммунных расстройств могут развиваться через несколько месяцев после начала приема препарата для лечения ВИЧ-инфекции."}},{"type":"paragraph","data":{"text":"Одно из таких заболеваний — болезнь Грейвса, поражающая щитовидную железу. Её симптомы могут включать быстрое или нерегулярное сердцебиение, дрожание частей тела или всего тела (тремор), чрезмерное беспокойство и избыточные движения (гиперактивность), слабость, начинающуюся с рук и ног и распространяющуюся на туловище."}},{"type":"paragraph","data":{"text":"Если у Вас возникает любой из симптомов инфекции и воспаления, или если Вы заметили какие-либо симптомы, описанные выше, немедленно сообщите Вашему лечащему врачу. Не принимайте другие лекарственные препараты для лечения инфекции без рекомендации Вашего лечащего врача."}},{"type":"paragraph","data":{"text":"Боль в суставах, скованность и проблемы с костями"}},{"type":"paragraph","data":{"text":"У некоторых пациентов, принимающих комбинированную терапию ВИЧ-инфекции, развивается состояние, называемое остеонекрозом. При этом состоянии часть костной ткани отмирает из-за уменьшения кровоснабжения кости. Вероятнее всего, это состояние может развиться у пациентов:"}},{"type":"list","data":{"style":"ordered","items":["если они длительное время принимают несколько препаратов для лечения ВИЧ- инфекции;","если они также принимают гормональные противовоспалительные лекарственные препараты (глюкокортикоиды);","если они употребляют алкоголь;","если их иммунная система очень ослаблена;","если они имеют избыточную массу тела."]}},{"type":"paragraph","data":{"text":"Признаки остеонекроза включают:"}},{"type":"list","data":{"style":"ordered","items":["скованность в суставах;","болезненность и боль (особенно в бедре, колене или плече)."]}},{"type":"paragraph","data":{"text":"Если Вы заметили какой-либо из этих симптомов, сообщите Вашему лечащему врачу."}},{"type":"paragraph","data":{"text":"Сообщение о нежелательных реакциях"}},{"type":"paragraph","data":{"text":"Если у Вас возникают какие-либо нежелательные реакции, проконсультируйтесь с врачом. К ним также относятся любые нежелательные реакции, не указанные в листке-вкладыше. Вы также можете сообщить о нежелательных реакциях напрямую (см. ниже). Сообщая о нежелательных реакциях, Вы помогаете получить больше сведений о безопасности препарата."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Если Вы приняли препарата Олитид больше, чем следовало"}},{"type":"paragraph","data":{"text":"Если Вы приняли препарата Олитид больше, чем предусмотрено, Вам необходимо немедленно обратиться к врачу, который проверит, нет ли у Вас признаков токсического действия препарата, и при необходимости назначит лечение."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Сообщите лечащему врачу о том, что Вы недавно принимаете, недавно принимали или можете начать принимать какие-либо другие препараты."}},{"type":"paragraph","data":{"text":"Некоторые лекарственные препараты могут влиять на то, как работает препарат Олитид, или увеличивать вероятность появления нежелательных реакций."}},{"type":"list","data":{"style":"ordered","items":["фенитоин и \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/2360.html?XFrom=www.lsgeotar.ru\"\u003eфенобарбитал\u003c/a\u003e (препараты, применяемые для лечения эпилепсии);","рифампицин (препарат, применяемый для лечения туберкулеза и других бактериальных инфекций);","метадон (препарат, используемый для лечения наркотической зависимости). Олитид увеличивает скорость, с которой метадон выводится из организма, и это может привести к появлению симптомов отмены. Если Вы принимаете метадон и Вам назначили препарат Олитид, Вам нужно сказать об этом своему наркологу. Возможно, он сочтет необходимым изменить Вашу дозу метадона."]}},{"type":"paragraph","data":{"text":"Сообщите Вашему лечащему врачу, если Вы принимаете любой из перечисленных препаратов. Ваш лечащий врач может принять решение о коррекции дозы или необходимости проведения дополнительных осмотров."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Перед приемом препарата Олитид проконсультируйтесь с лечащим врачом."}},{"type":"paragraph","data":{"text":"Реакция повышенной чувствительности (гиперчувствительность)"}},{"type":"paragraph","data":{"text":"Применение препарата Олитид может вызвать серьезную аллергическую реакцию, известную как реакция повышенной чувствительности, которая может угрожать Вашей жизни."}},{"type":"paragraph","data":{"text":"Если у Вас раньше возникали аллергические реакции при приеме препаратов, содержащих \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/9.html?XFrom=www.lsgeotar.ru\"\u003eабакавир\u003c/a\u003e, Вам нельзя принимать препарат Олитид. Если Вы раньше принимали препараты, содержащие \u003ca target=\"_blank\" href=\"https://www.lsgeotar.ru/pharma_mnn/9.html?XFrom=www.lsgeotar.ru\"\u003eабакавир\u003c/a\u003e, и Вам их отменили по другим причинам, то начинать лечение препаратом Олитид Вам можно только при наличии быстрого доступа к медицинской помощи."}},{"type":"paragraph","data":{"text":"Внимательно прочтите всю информацию под заголовком «Реакции повышенной чувствительности»."}},{"type":"paragraph","data":{"text":"Состояния, за которыми Вам необходимо следить"}},{"type":"paragraph","data":{"text":"У некоторых пациентов, принимающих лекарственные препараты для лечения ВИЧ- инфекции, развиваются состояния, которые могут быть серьезными."}},{"type":"paragraph","data":{"text":"К ним относятся:"}},{"type":"list","data":{"style":"ordered","items":["накопление молочной кислоты и поражение печени;","симптомы инфекции и воспаления;","боли в суставах, скованность и проблемы с костями."]}},{"type":"paragraph","data":{"text":"Вам необходимо знать о важных признаках и симптомах, за которыми Вам необходимо следить, пока Вы принимаете препарат Олитид."}},{"type":"paragraph","data":{"text":"Защита других людей"}},{"type":"paragraph","data":{"text":"ВИЧ-инфекция передается половым путем при контактах с инфицированными лицами или при контакте с инфицированной кровью (например, при использовании одних и тех же игл для инъекций). Вы все еще можете заразить ВИЧ-инфекцией, когда принимаете препарат Олитид, хотя риск снижается благодаря эффективной антиретровирусной терапии. Обсудите с Вашим лечащим врачом меры предосторожности во избежание передачи инфекции другим людям."}},{"type":"paragraph","data":{"text":"Перед применением препарата полностью прочитайте листок-вкладыш, поскольку в нем содержатся важные для Вас сведения."}},{"type":"paragraph","data":{"text":"Сохраните листок-вкладыш. Возможно, Вам потребуется прочитать его еще раз."}},{"type":"paragraph","data":{"text":"Если у Вас возникли дополнительные вопросы, обратитесь к лечащему врачу."}},{"type":"paragraph","data":{"text":"Препарат назначен именно Вам. Не передавайте его другим людям. Он может навредить им, даже если симптомы их заболевания совпадают с Вашими."}},{"type":"paragraph","data":{"text":"Если у Вас возникли какие-либо нежелательные реакции, обратитесь к лечащему врачу. 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