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Оптимальный режим дозирования определяет врач. Следует строго соблюдать соответствие используемой лекарственной формы конкретного препарата показаниям к применению и режиму дозирования.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Устанавливают индивидуально, в зависимости от показаний, клинической ситуации и применяемой лекарственной формы."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"  Повышенная чувствительность к фолиевой кислоте; длительная терапия пациентов с нелеченым дефицитом кобаламинов (например, пернициозная анемия, недостаточность витамина В\u003csub\u003e12\u003c/sub\u003e, вегетарианство); злокачественные новообразования; беременные женщины без установленного дефицита фолиевой кислоты и/или наличия факторов риска развития дефектов нервной трубки у плода; период грудного вскармливания - в зависимости от лекарственной формы; детский и подростковый возраст до 18 лет.  "}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"При пернициозной анемии фолиевую кислоту следует применять только совместно с цианокобаламином, поскольку фолиевая кислота, стимулируя гемопоэз, не предупреждает развития неврологических осложнений (в т.ч. фуникулярного миелоза). Длительное применение фолиевой кислоты (особенно в высоких дозах) не рекомендуется из-за риска снижения концентрации в крови цианокобаламина."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Противопоказано применение у беременных женщин без установленного дефицита фолиевой кислоты и/или наличия факторов риска развития дефектов нервной трубки у плода. Возможно применение при беременности по показаниям в рекомендуемых дозах."}},{"type":"paragraph","data":{"text":"Возможно применение в период лактации (грудного вскармливания) строго по показаниям, в рекомендуемых дозах и лекарственных формах. Необходимо строго следовать указаниям в инструкциях препаратов фолиевой кислоты по противопоказаниям к применению в период грудного вскармливания конкретных лекарственных форм фолиевой кислоты."}},{"type":"header","data":{"text":"Применение у детей","level":4}},{"type":"paragraph","data":{"text":"Противопоказано применение у детей и подростков в возрасте до 18 лет."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны пищеварительной системы:\u003c/i\u003e редко - анорексия, тошнота, вздутие живота, метеоризм, горечь во рту."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСо стороны иммунной системы:\u003c/i\u003e редко - анафилактические реакции (включая шок)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eАллергические реакции:\u003c/i\u003e редко - эритема, сыпь, зуд, крапивница, одышка."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Аллергические реакции - кожная сыпь, кожный зуд, бронхоспазм, эритема, гипертермия. При появлении каких либо побочных эффектов, неописанных в данной инструкции, следует информировать своего лечащего врача."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Дозы фолиевой кислоты до 4 - 5 мг переносятся хорошо. Более высокие дозы могут вызвать: нарушения со стороны центральной нервной системы (раздражительность и бессонница) и желудочно-кишечного тракта (тошнота, абдоминальные боли, метеоризм)."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При одновременном применении с хлорамфениколом, неомицином, полимиксинами, тетрациклинами всасывание фолиевой кислоты уменьшается."}},{"type":"paragraph","data":{"text":"При одновремнном применении анальгетиков (длительная терапия), противосудорожных препаратов (в т.ч. фенитоин, карбамазепин), эстрогенов, парентеральных контрацептивов увеличивается потребность в фолиевой кислоте."}},{"type":"paragraph","data":{"text":"При одновременном применении фолиевой кислоты возможно снижение концентрации в плазме фенобарбитала, фенитоина, примидона, повышается риск эпилептического припадка."}},{"type":"paragraph","data":{"text":"При одновременном применении антацидов (в т.ч. препараты кальция, алюминия и магния), колестирамина, сульфонамидов (в т.ч. сульфасалазин) снижается абсорбция фолиевой кислоты. Антациды следует применять спустя 2 ч после приема фолиевой кислоты, колестирамин - за 4-6 ч до или спустя 1 ч после приема фолиевой кислоты."}},{"type":"paragraph","data":{"text":"При одновременном применении метотрексат, пириметамин, триамтерен, триметоприм ингибируют дигидрофолатредуктазу и снижают эффект фолиевой кислоты."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"При пернициозной анемии фолиевую кислоту следует применять только совместно с цианокобаламином, поскольку фолиевая кислота, стимулируя гемопоэз, не предупреждает развития неврологических осложнений (в т.ч. фуникулярного миелоза)."}},{"type":"paragraph","data":{"text":"Длительное применение фолиевой кислоты (особенно в высоких дозах) не рекомендуется из-за риска снижения концентрации в крови цианокобаламина."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Не влияет."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"По 5 контурных ячейковых упаковок по 10 таблеток в пачке."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В защищенном от света и влаги месте, при температуре не выше 25?С. Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года. Не использовать после окончания срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Открытое акционерное общество «Борисовский завод медицинских препаратов», Республика Беларусь, Минская обл., г. Борисов, ул. Чапаева 64/27, тел/факс +375(177)744280."}}]}],"source":null},"description_toggle":false,"short_description":"Витамин группы B (витамин Bc, B9). В организме фолиевая кислота восстанавливается до тетрагидрофолиевой кислоты, являющейся коферментом, участвующим в различных метаболических процессах. Необходима для нормального созревания мегалобластов и образования нормобластов. Стимулирует эритропоэз, участвует в синтезе аминокислот (в т.ч. метионина, серина), нуклеиновых кислот, пуринов и пиримидинов, в обмене холина, гистидина. При беременности защищает организм от действия тератогенных факторов. Способствует нормальному созреванию и функционированию плаценты. После приема внутрь хорошо всасывается из ЖКТ. Связывание с белками плазмы высокое. Метаболизируется в печени и тканях. Выводится с желчью и с мочой. Проникает через ГЭБ, плаценту, выделяется с грудным молоком. Макроцитарная гиперхромная анемия, вызванная дефицитом фолиевой кислоты. В составе комбинированной терапии следующих заболеваний: анемия и лейкопения, вызванные лекарственными средствами и ионизирующей радиацией; спру; хронические гастроэнтериты; туберкулез кишечника. На этапе планирования и во время беременности для профилактики развития дефектов нервной трубки у плода при наличии факторов риска у матери. Лечение мегалобластной анемии, обусловленной дефицитом или повышенной утилизацией фолиевой кислоты (в т.ч. при беременности, синдроме мальабсорбции).","substance":[],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":false,"comments":null,"image_alt":"Фолиевая кислота - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/51527/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/51527/share_default/"}},"diseases":[{"id":"25","title":"Туберкулез других органов","slug":"25-tuberkulez_drugih_organov"},{"id":"320","title":"Фолиеводефицитная анемия","slug":"320-folievodefitsitnaya_anemiya"},{"id":"344","title":"Агранулоцитоз","slug":"344-agranulotsitoz"},{"id":"874","title":"Другие неинфекционные гастроэнтериты и колиты","slug":"874-drugie_neinfektsionnye_gastroenterity_i_kolity"}],"other_packages":[{"id":92098,"title":"Фолиевая кислота","subtitle":{"full":"Таблетки, 50 шт, 1 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