Фармакологическое действие — антиагрегационное, противошоков... Инструкция
Показания к применению
Нарушение капиллярного кровотока, профилактика и лечение шока (травматического, операционного, ожогового); профилактика и лечение тромбозов, тромбофлебитов, эндартериита; операции на сердце, проводимые с использованием аппарата искусственного кровообращения (для добавления к перфузионной жидкости); улучшение местной циркуляции в сосудистой и пластической ...
Тромбоцитопения, заболевания почек (с анурией), сердечная недостаточность, случаи, когда не следует вводить большое количество жидкости, аллергия на декстран в анамнезе.
Инструкция
Описание
Прозрачная бесцветная или слабо-желтая жидкость.
Фармакологические свойства
Фармакологическое действие — антиагрегационное, противошоковое, дезинтоксикационное, плазмозамещающее, улучшающее микроциркуляцию.
Показания к применению
Нарушение капиллярного кровотока, профилактика и лечение шока (травматического, операционного, ожогового); профилактика и лечение тромбозов, тромбофлебитов, эндартериита; операции на сердце, проводимые с использованием аппарата искусственного кровообращения (для добавления к перфузионной жидкости); улучшение местной циркуляции в сосудистой и пластической хирургии; дезинтоксикация (при ожогах, перитоните, панкреатите и т.д.); заболевания сетчатки и зрительного нерва, воспалительные процессы роговицы и сосудистой оболочки.
Противопоказания
Тромбоцитопения, заболевания почек (с анурией), сердечная недостаточность, случаи, когда не следует вводить большое количество жидкости, аллергия на декстран в анамнезе.
Способ применения и дозы
В/в, капельно.Доза устанавливается индивидуально и зависит от клинической ситуации и состояния больного.С целью предупреждения и лечения нарушений капиллярного кровотока, связанных с травматическим, операционным и ожоговым шоком, применяют в/в капельно 400–1000мл/сут (в течение не менее 30–60 мин) обычно 1 (реже 2) раза в сутки.При оперативных вмешательствах на сердце и сосудах вводят до операции в/в капельно по 10мл/кг, во время операции— 400–500мл и в течение 5–6 дней после операции— по 10мл/кг на введение.Детям общая доза не должна превышать 15мл/кг/сут.При сердечно-сосудистых операциях детям в возрасте до 2–3 лет вводят по 10мл/кг 1 раз в сутки (в течение 60 мин), до 8 лет— 7–10мл/кг (1–2 раза в сутки), до 13 лет— по 5–7мл/кг (1–2 раза в сутки), старше 14 лет— дозу для взрослых. Для дезинтоксикации вводят 5–10мл/кг в течение 60–90 мин.При операциях с искусственным кровообращением Реополиглюкин добавляют в кровь из расчета 10–20мл/кг массы тела для заполнения насоса оксигенатора. Концентрация Реополиглюкина в перфузионном растворе не должна превышать 3%. В послеоперационном периоде препарат используют в тех же дозах, что и при лечении шоковых состояний.С целью дезинтоксикации вводят в/в капельно в разовой дозе от 500 до 1200мл (у детей 5–10мл/кг) в течение 60–90 мин. При необходимости можно в первые сутки перелить еще 500мл препарата (у детей введение препарата в первые сутки может быть повторено в тех же дозах). В последующие дни препарат вводят капельно, взрослым— в суточной дозе 500мл, детям— из расчета 5–10мл/кг. Целесообразно совместно вводить кристаллоидные растворы (Рингера, Рингера-ацетата и др.) в таком количестве, чтобы нормализовать водно-электролитный баланс (особенно важно при лечении обезвоженных больных и после хирургических операций). Препарат, как правило, вызывает увеличение диуреза (уменьшение диуреза указывает на обезвоживание организма больного).В офтальмологической практике применяется путем электрофореза. Процедуру проводят 1 раз в день. Применяют по 10мл (с положительного и отрицательного полюса; плотность тока до 1,5 мА/см2).
Взаимодействие с другими лекарственными средствами
Необходимо предварительно проверить на совместимость декстрана с ЛС, которые запланированы для введения в инфузионный раствор.
Условия хранения
В сухом месте, при температуре 10–25°C. Допускается замораживание.Хранить в недоступном для детей месте.
Срок годности
4 года. Не применять по истечении срока годности, указанного на упаковке.2000-2017. Регистр лекарственных средств России
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