в блистере 10 шт.; в пачке картонной 1 или 2 блистера.
Описание
Препарат Тофф плюс - средство для лечения простудных заболеваний. Оказывает седативное, противокашлевое, противоаллергическое, сосудосуживающее, противоотечное, анальгезирующее, жаропонижающее действия.
Фармакотерапевтическая группа
ОРЗ и "простуды" симптомов средство устранения (анальгезирующее ненаркотическое средство+противокашлевое опиоидное средство+альфа-адреномиметик+H1-гистаминовых рецепторов блокатор)
Фармакологические свойства
Парацетамол оказывает жаропонижающее и анальгетическое действие. Фенилэфрин - альфа-адерномиметик, оказывает сосудосуживающее действие, способствует устранению заложенности носа, уменьшению слизистого отделяемого секрета из полости носа. Хлорфенамин - Н1-гистаминоблокатор, оказывает противоаллергическое действие, подавляет симптомы аллергического ринита (уменьшает проницаемость сосудов, устраняет отечность и гиперемию слизистой оболочки полости носа). Декстрометорфан - противокашлевое средство, по силе действия близок к кодеину, повышает порог чувствительности кашлевого центра продолговатого мозга, подавляет кашель любого происхождения, устраняет раздражающее действие сухого непродуктивного кашля и хорошо переносится всеми возрастными группами. Оказывает некоторое седативное действие. Не обладает обезболивающим, наркотическим и снотворным действием. Не угнетает дыхательный центр и активность реснитчатого эпителия. Начало действия - через 20-30 мин, длительность - 4-4,5 ч.
В период лечения следует воздерживаться от приема алкоголя. Необходимо соблюдать осторожность при выполнении работы, требующей концентрации внимания, повышенной скорости двигательных и психических реакций.
У лиц, страдающих хроническим алкоголизмом, прием терапевтических доз препарата Тофф плюс может вызвать тяжелую печеночную недостаточность.
Применение при беременности и в период грудного вскармливания
Противопоказан при беременности и в период лактации.
Способ применения и дозы
Внутрь, взрослым - по одной капсуле каждые 4-6 часов, но не более 4 капсул в сутки. Прием в качестве жаропонижающего средства не более 3 дней без консультации врача.
Побочное действие
Со стороны сердечно-сосудистой системы: артериальная гипертензия. Со стороны нервной системы и органов чувств: головокружение, сонливость, повышенная возбудимость, мидриаз, парез аккомодации, повышение внутриглазного давления. Со стороны пищеварительной системы: сухость во рту, эпигастральная боль, тошнота, рвота, гепатотоксическое действие. Со стороны органов кроветворения: анемия, тромбоцитопения, гемолитическая анемия, апластическая анемия. Со стороны мочевыделительной системы: задержка мочи, нефротоксичность (папиллярный некроз). Аллергические реакции (в т.ч. кожная сыпь, зуд, ангионевротический отек), бронхообструкция. Аллергические реакции могут быть замедленными (в связи с наличием в составе метилпарагидроксибензоата и пропилпарагидроксибензоата).
Передозировка
Симптомы (обусловлена парацетамолом, проявляется после приема свыше 10-15 г): бледность кожных покровов, анорексия, тошнота, рвота, гепатонекроз, повышение активности “печеночных” трансаминаз, увеличение протромбинового времени. Лечение: промывание желудка с последующим назначением активированного угля, симптоматическая терапия.
Взаимодействие с другими лекарственными средствами
Хлорфенирамин, назначенный одновременно с ингибиторами МАО и фуразолидоном, может привести к развитию гипертонического криза, психомоторному возбуждению, повышению температуры.
Трициклические антидепрессанты усиливают симпатомиметическое действие; одновременное назначение галотана повышает риск развития желудочковой аритмии.
Снижает гипотензивное действие гуанетидина, который, в свою очередь, усиливает альфа-адреностимулирующую активность фенилэфрина.
Особые указания
В период лечения не следует принимать другие лекарственные средства, содержащие вещества, входящие в состав препарата.
У лиц, страдающих хроническим алкоголизмом, прием терапевтических доз препарата может вызвать тяжелую печеночную недостаточность.
В период лечения необходимо воздерживаться от употребления этанола (возможно развитие гепатотоксического действия).
Влияние на способность управлять автомобилем и движущимися механизмами
В период лечения следует воздерживаться от приема алкоголя. Необходимо соблюдать осторожность при выполнении работы, требующей концентрации внимания, повышенной скорости двигательных и психических реакций.
Форма выпуска
капсулы в блистере 10 шт.; в пачке картонной 1 или 2 блистера.
Условия хранения
В защищенном от света месте, при температуре не выше 25 °C.
Хранить в недоступном для детей месте.
Срок годности
3 года.
Не применять по истечении срока годности, указанного на упаковке.
Для описания товара использована информация от партнера 36.6
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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