Ведикардол Синтез Таблетки, пачка, 30 шт, 12.5 мг, для внутреннего применения, для рта, цвет белый

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При недостаточности \nантигипертензивного эффекта через 2 недели терапии доза может быть \nувеличена в 2 раза. Максимальная рекомендованная суточная доза препарата\n составляет 50 мг 1 раз/сут, ее можно разделять на 2 приема.\n"}},{"type":"paragraph","data":{"text":"\n\t Ишемическая болезнь сердца:\n"}},{"type":"paragraph","data":{"text":"\n\t Начальная доза составляет по 12.5 мг 2 раза/сут в первые 2 дня \nлечения. Затем по 25 мг 2 раза/сут. При недостаточности антиангинального\n эффекта через 2 недели терапии доза может быть увеличена в 2 раза. \nМаксимальная рекомендованная суточная доза препарата составляет 100 \nмг/сут, разделенные на 2 приема.\n"}},{"type":"paragraph","data":{"text":"\n\t Хроническая сердечная недостаточность\n"}},{"type":"paragraph","data":{"text":"\n\t Дозу подбирают индивидуально, под тщательным наблюдением врача. \nРекомендованная начальная доза составляет 3.125 мг 2 раза/сут в течение 2\n недель. При хорошей переносимости дозу увеличивают с интервалом не \nменее 2 недель до 6.25 мг 2 раза/сут, затем - до 12.5 мг 2 раза/сут и \nдалее - до 25 мг 2 раза/сут. Дозу следует увеличивать до максимальной, \nкоторая хорошо переносится больным. У пациентов с массой тела менее 85 \nкг целевая доза составляет 50 мг/сут; у пациентов с массой тела более 85\n кг целевая доза - 75-100 мг/сут.\n"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\n\t Со стороны ЦНС и периферической нервной системы: головокружение, \nголовная боль (как правило, несильная и в начале лечения), потеря \nсознания, миастения (чаще в начале лечения), повышенная утомляемость, \nдепрессия, нарушение сна, парестезии.\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны сердечно-сосудистой системы: брадикардия, ортостатическая \nгипотензия, AV-блокада II-III степени; редко - нарушение периферического\n кровообращения, прогрессирование сердечной недостаточности (в период \nувеличения дозы), отеки нижних конечностей, стенокардия, выраженное \nснижение АД, перемежающаяся хромота.\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны пищеварительного тракта: сухость во рту, тошнота, диарея \nили запор, рвота, боль в животе, потеря аппетита, повышение активности \nпеченочных трансаминаз.\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны системы кроветворения: редко - тромбоцитопения, лейкопения.\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны обмена веществ: увеличение массы тела, нарушение углеводного обмена.\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны дыхательной системы: одышка и бронхоспазм (у предрасположенных больных).\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны органа зрения: нарушение зрения, уменьшение слезоотделения.\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны костно-мышечной системы: миалгия, артралгия, боли в конечностях.\n"}},{"type":"paragraph","data":{"text":"\n\t Со стороны мочевыделительной системы: редко - нарушение мочеиспускания, нарушение функции почек.\n"}},{"type":"paragraph","data":{"text":"\n\t Аллергические реакции: кожные проявления, заложенность носа.\n"}},{"type":"paragraph","data":{"text":"\n\t Дерматологические реакции: обострение псориаза.\n"}},{"type":"paragraph","data":{"text":"\n\t Прочие: гриппоподобный синдром, чиханье.\n"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\n\t Симптомы: снижение АД (сопровождающееся головокружением или \nобмороком), брадикардия. Возможно возникновение одышки вследствие \nбронхоспазма и рвоты. В тяжелых случаях возможны кардиогенный шок, \nнарушение дыхания, спутанность сознания, нарушения проводимости.\n"}},{"type":"paragraph","data":{"text":"\n\t Лечение: необходимо проводить мониторинг и коррекцию жизненно важных \nпоказателей, при необходимости - в ОИТ. Проводится симптоматическая \nтерапия. Целесообразно в/в введение м-холиноблокаторов (атропин), \nадреномиметиков (эпинефрин, норэпинефрин).\n"}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\n\t Карведилол может потенцировать действие других одновременно \nпринимаемых антигипертензивных средств или препаратов, которые оказывают\n гипотензивный эффект (нитраты).\n"}},{"type":"paragraph","data":{"text":"\n\t При совместном применении карведилола и дилтиазема могут развиваться нарушения проводимости сердца и нарушения гемодинамики.\n"}},{"type":"paragraph","data":{"text":"\n\t При одновременном приеме карведилола и дигоксина увеличивается \nконцентрация последнего и может увеличиваться время AV проведения.\n"}},{"type":"paragraph","data":{"text":"\n\t Карведилол может потенцировать действие инсулина и пероральных \nгипогликемических средств, при этом симптомы гипогликемии (особенно \nтахикардия) могут маскироваться, поэтому у больных сахарным диабетом \nрекомендуется проводить регулярный контроль уровня сахара в крови.\n"}},{"type":"paragraph","data":{"text":"\n\t Ингибиторы микросомального окисления (циметидин) усиливают, а \nиндукторы (фенобарбитал, рифампицин) ослабляют гипотензивный эффект \nкарведилола.\n"}},{"type":"paragraph","data":{"text":"\n\t Препараты, снижающие содержание катехоламинов (резерпин, ингибиторы \nМАО), повышают риск развития артериальной гипотензии и выраженной \nбрадикардии.\n"}},{"type":"paragraph","data":{"text":"\n\t При одновременном применении циклоспорина увеличивается концентрация \nпоследнего (рекомендуется коррекция суточной дозы циклоспорина).\n"}},{"type":"paragraph","data":{"text":"\n\t Одновременное назначение клонидина может потенцировать антигипертензивный и урежающий сердечный ритм эффекты карведилола.\n"}},{"type":"paragraph","data":{"text":"\n\t Общие анестетики усиливают отрицательный инотропный и гипотензивный эффект карведилола.\n"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"\n\t Терапию следует проводить длительно и не прекращать резко, особенно у \nбольных ИБС, т.к. это может приводить к ухудшению течения основного \nзаболевания. В случае необходимости снижение дозы препарата должно быть \nпостепенным, в течение 1-2 недель.\n"}},{"type":"paragraph","data":{"text":"\n\t В начале терапии Ведикардолом или при повышении дозы препарата у \nпациентов, особенно пожилого возраста, может отмечаться избыточное \nснижение АД, преимущественно при вставании. Необходима коррекция дозы \nпрепарата. У больных с хронической сердечной недостаточностью при \nподборе дозы возможно нарастание симптомов сердечной недостаточности, \nпоявление отеков. При этом не следует увеличивать дозу Ведикардола, \nрекомендовано назначение больших доз диуретиков вплоть до стабилизации \nсостояния больного.\n"}},{"type":"paragraph","data":{"text":"\n\t Рекомендуется постоянное мониторирование ЭКГ и АД при одновременном \nназначении Ведикардола и блокаторов медленных кальциевых каналов, \nпроизводных фенилалкиламина (верапамил), производных бензодиазепина \n(дилтиазем), а также - с антиаритмическими средствами I класса.\n"}},{"type":"paragraph","data":{"text":"\n\t Рекомендуется контролировать функцию почек у пациентов с хронической \nпочечной недостаточностью, артериальной гипотензией и хронической \nсердечной недостаточностью.\n"}},{"type":"paragraph","data":{"text":"\n\t В случае проведения хирургического вмешательства с использованием \nобщей анестезии следует предупредить анестезиолога о предшествующей \nтерапии Ведикардолом.\n"}},{"type":"paragraph","data":{"text":"\n\t Ведикардол не влияет на концентрацию глюкозы в крови и не вызывает \nизменений показателей теста толерантности к глюкозе у больных \nинсулиннезависимым сахарным диабетом.\n"}},{"type":"paragraph","data":{"text":"\n\t Больным с феохромоцитомой до начала терапии необходимо назначить альфа-адреноблокаторы.\n"}},{"type":"paragraph","data":{"text":"\n\t При назначении пациентам, использующим контактные линзы, следует \nучитывать, что препарат может вызвать уменьшение слезоотделения.\n"}},{"type":"paragraph","data":{"text":"\n\t В период лечения избегать употребления этанола.\n"}},{"type":"paragraph","data":{"text":"\n\t Влияние на способность к вождению автотранспорта и управлению механизмами\n"}},{"type":"paragraph","data":{"text":"\n\t Не рекомендуется управлять автомобилем в начале терапии и при \nувеличении дозы Ведикардола. Следует воздержаться от других видов \nдеятельности, связанных с необходимостью высокой концентрации внимания и\n быстрых психомоторных реакций.\n"}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"В сухом, защищенном от света месте, при температуре не выше 25С.\u003cbr\u003e"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. \u003cbr\u003e"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"По рецепту. \u003cbr\u003e"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Синтез ОАО\u003cbr\u003e"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"Синтез ОАО"}}]}],"source":null},"description_toggle":false,"short_description":"Альфа- и бета-адреноблокатор. Карведилол оказывает сочетанное неселективное действие, обусловленное блокадой 1-, 2- и 1-адренорецепторов. Препарат не имеет собственной симпатомиметической активности, обладает мембраностабилизирующими свойствами. Благодаря блокаде -адренорецепторов сердца снижается АД, сердечный выброс и уменьшается ЧСС. Карведилол подавляет ренин-ангиотензин-альдостероновую систему посредством блокады - адренорецепторов почек, вызывая снижение активности ренина плазмы. Блокируя-адренорецепторы, препарат может вызывать расширение периферических сосудов, тем самым снижая ОПСС. Сочетание блокады - адренорецепторов и вазодилатации оказывает следующие воздействия: при артериальной гипертензии - снижение АД; при ИБС - антиангинальное действие; у пациентов с дисфункцией левого желудочка и недостаточностью кровообращения благоприятно влияет на гемодинамические показатели, повышает фракцию выброса левого желудочка и способствует уменьшению его размеров.","substance":[{"id":250,"title":"Карведилол","title_latin":"Carvedilolum","slug":"karvedilol_250"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Ведикардол Синтез - фото 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