Возраст до 6 лет. Повышенная чувствительность к компонентам препарата. С осторожностью: У пациентов с легочным туберкулезом в активной или хронической форме. У пациентов с бактериальными, вирусными или грибковыми инфекциями дыхательных путей.
Возраст до 6 лет. Повышенная чувствительность к компонентам препарата. С осторожностью: У пациентов с легочным туберкулезом в активной или хронической форме. У пациентов с бактериальными, вирусными или грибковыми инфекциями дыхательных путей.
Способ применения и дозы
Альвеско применяют только для пероральной ингаляции. Препарат следует принимать ежедневно в течение длительного периода времени. Альвеско дозируют индивидуально. Начальную дозу следует подбирать в зависимости от тяжести состояния. При достижении желаемого клинического эффекта, дозу следует снизить до минимальной, необходимой для контролирования проявлений заболевания. Взрослым и подросткам старше 12 лет, пациентам пожилого возраста При бронхиальной астме от легкой до средней степени тяжести Рекомендованная ежедневная доза составляет от 160 мкг до 640 мкг; дозу 640 мкг следует делить на 2 приема в сутки. При бронхиальной астме тяжелой степени Доза может быть увеличена максимально до 640 мкг 2 раза/сут ежедневно. Улучшение проявлений заболевания наступает в течение 24 ч после приема Альвеско. Предполагается, что максимальный эффект от лечения - как и с другими ингаляционными ГКС - достигается после 2-3 месячного применения препарата. Пациенты не должны прекращать лечение, даже при отсутствии симптомов бронхиальной астмы. Пациентам пожилого возраста Коррекция дозы не требуется. Детям старше 6 лет Рекомендованная ежедневная доза составляет 80-160 мкг 1 раз/сут. или по 80 мкг 2 раза/сут. Альвеско можно применять со спейсером или без него. Если использование спейсера необходимо, рекомендуется применять спейсер AeroChamberPlus. Пациентам с почечной или печеночной недостаточностью Коррекция дозы не требуется. Взрослые и подростки, постоянно принимающие пероральные ГКС У пациентов с тяжелым течением бронхиальной астмы, которые зависят от пероральной терапии ГКС (например, преднизолоном), доза Альвеско составляет 640 мкг 2 раза/сут. Перевод пациентов с перорального ГКС на Альвеско возможен в стадии ремиссии. Альвеско в дозе 640 мкг 2 раза/сут следует применять в течение 10 дней в комбинации с пероральным ГКС. Дозу перорального ГКС следует затем постепенно снижать каждую неделю до минимальной эффективной дозы, с уменьшением ежедневной дозы не более, чем на 2,5 мг каждый раз.
Побочное действие
Нечасто (>1/1000, <1/100). Редко (>1/10 000, <1/1000). Со стороны сердечно-сосудистой системы Редко - усиленное сердцебиение**, повышение АД. Со стороны пищеварительной системы Не часто - тошнота, рвота*, неприятный вкус. Редко - боль в животе*, диспепсия*. Местные реакции Не часто -ощущение раздражения и першения в горле, сухость слизистой оболочки полости рта и глотки. Аллергические реакции Редко - ангионевротический отек, гиперчувствительность. Инфекционные и паразитарные заболевания Не часто - грибковые инфекции полости рта*. Со стороны нервной системы Не часто - головная боль*, Дисфония Со стороны дыхательной системы Нечасто - кашель после ингаляции*, парадоксальный бронхоспазм*. Со стороны кожных покровов Не часто - экзема, кожная сыпь.
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