СОСТАВ И ФОРМА ВЫПУСКА Антигельминтный препарат, содержащий 40 мг оксибендазола, 200 мг никлозамида и наполнитель. Поливеркан представляет собой сахарный кубик массой 8 грамм, светло-желтого цвета, с разделяющей бороздкой посередине, растворимый в воде. Препарат расфасовывают по 8 кубиков в герметично закрытые пластмассовые блистеры, которые упаковываются в картонные коробки по одному или по сто штук. Каждую упаковку маркируют с указанием названия и назначения препарата, фирмы-изготовителя, номера серии, срока годности и снабжают временным наставлением по применению.
ФАРМАКОЛОГИЧЕСКИЕ СВОЙСТВА Поливеркан относится к комбинированным антигельминтным препаратам. Препарат обладает широким спектром действия на все стадии развития нематод и цестод, паразитирующих у собак и кошек, в том числе Toxocara canis, Toxascaris leonine, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus granulosus, Echinococcus multilocularis, Diphyllobothrium latum, Multiceps multiceps. Никлозамид, входящий в состав Поливеркана, активен против цестод. Механизм его действия заключается в блокировке абсорбции паразитом глюкозы. Никлозамид практически не всасывается в кишечнике, выводится с фекалиями в неизменном виде. Оксибендазол, являющийся производным бензимидазола, обладает широким спектром нематоцидного действия. Механизм его действия заключается в блокировке фумаратредуктазы и нарушении энергетического метаболизма у гельминта. Часть препарата всасывается в кишечнике, трансформируется в организме и выводится с мочой и частично с фекалиями в неизменном виде и в виде метаболитов. Поливеркан малотоксичен для теплокровных животных, хорошо переносятся кошками и собаками, в рекомендуемых дозах не обладает эмбриотоксическим и тератогенным свойствами.
ДОЗЫ И СПОСОБ ПРИМЕНЕНИЯ Поливеркан применяют собакам и кошкам для профилактики и лечения токсокароза, токсаскаридоза, унцинариоза, анкилостоматоза, дипилидиоза, дифиллоботриоза. Препарат назначают перорально в следующих разовых дозах: котятам и щенкам массой 0,5 кг 1/4 брикета; кошкам и собакам с массой тела 1-5 кг 1/2 брикета; собакам с массой 5-10 кг 1 брикет; собакам с массой 10-20 кг 2 брикета; собакам с массой 20-30 кг 3 брикета; собакам с массой 30-40 кг 4 брикета; собакам с массой 40-50 кг 5 брикетов; собакам с массой 50 кг и выше 6 брикетов. Максимальная доза на животное – не более шести брикетов. Собакам сахарный кубик скармливают с руки хозяина или добавляют в пищу (в воду), кошкам - добавляют в пищу или, растворив препарат в небольшом количестве воды, вводят его через рот шприцом. С лечебной целью дают двукратно с интервалом 10 дней, с профилактической однократно один раз в квартал.
ПРОТИВОПОКАЗАНИЯ Не рекомендуется применять в период беременности. Не использовать совместно с другими антигельминтными препаратами, в связи с возможным усилением их токсичности. Поливеркан не предназначен для продуктивных животных.
ПОБОЧНЫЕ ДЕЙСТВИЯ Побочных явлений и осложнений при применении Поливеркана в соответствии с настоящей инструкцией, как правило, не наблюдается. У некоторых животных при повышенной индивидуальной чувствительности к компонентам препарата может возникнуть рвота. При высокой степени инвазии паразитами могут появиться симптомы интоксикации. В этом случае животному назначают средства симптоматической терапии. При передозировке препарата у животного может наблюдаться угнетенное состояние, отказ от корма, избыточное слюноотделение, расстройство желудочно-кишечного тракта. В этом случае рекомендуется промывание желудка и симптоматическое лечение.
УСЛОВИЯ ХРАНЕНИЯ Хранят в упаковке изготовителя в сухом, защищенном от света и недоступном для детей и животных месте при температуре от 0 до 25 С. Гарантийный срок годности препарата – 4 года со дня изготовления.
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