Симптоматическое лечение метеоризма, избыточного газообразования и вздутия живота, связанных с расстройствами со стороны желудочно-кишечного тракта, в том числе, с функциональной диспепсией.
Противопоказания
Повышенная чувствительность к симетикону или другим компонентам препарата, детский возраст до 18 лет.
Инструкция
Состав
Активное вещество:
1 капсула содержит: симетикон – 120,00 мг
Вспомогательные вещества:
Желатин – 50,60 мг, глицерол – 19,60 мг
Описание
Новый препарат от газообразования и вздутия в формате гелевых капсул с жидким центром. Устраняет неприятные симптомы, схлопывая пузырьки газа в кишечнике всего за 3-6 секунд. Благодаря увеличенной концентрации активного вещества, для избавления от неприятных симптомов достаточно принять всего 1 капсулу Мотилегаз Форте 3 раза в день.
Фармакотерапевтическая группа
Прочие лекарственные препараты для лечения функциональных расстройств желудочно-кишечного тракта.
Фармакологические свойства
Фармакодинамика:
Симетикон – химически инертный полимер метилсилоксана, содержащий около 5% диоксида кремния.Симетикон обладает пеногасящими и противовспенивающими свойствами, значительно уменьшает поверхностное натяжение воды очищенной и модельных растворов поверхностно-активных веществ. Результаты экспериментов по пеногашению продемонстрировали полное разрушение пены в течение 3–6 секунд при добавлении жидкой суспензии симетикона в концентрации 0,1 мг/мл. Ниже этого порога полного разрушения пены не происходит. В качестве пеногасителя симетикон также эффективен в концентрации 0,1 мг/мл. Этот эффект длится более 24 часов.Механизм действия основан на распространении силиконовой жидкости по поверхности пленки пены, а также на локальном изменении поверхностного натяжения в области контакта. Таким образом, происходит быстрый дренаж жидкости, что способствует разрыву пленки, в следствие чего высвобождающийся газ получает возможность всасываться или выводиться естественным путем.
Фармакокинетика:
Симетикон – это химически инертная субстанция, не обладающая физиологической активностью, она не всасывается, проходит через пищеварительный тракт и выводится в неизменном виде.
Показания к применению
Симптоматическое лечение метеоризма, избыточного газообразования и вздутия живота, связанных с расстройствами со стороны желудочно-кишечного тракта, в том числе, с функциональной диспепсией.
Противопоказания
Повышенная чувствительность к симетикону или другим компонентам препарата, детский возраст до 18 лет.
Применение при беременности и в период грудного вскармливания
Клинические данные о воздействии симетикона при использовании во время беременности отсутствуют.Симетикон можно применять во время беременности только в том случае, если предполагаемая польза терапии для матери превосходит потенциальный риск для плода, принимая во внимание тот факт, что симетикон физиологически не активен и не всасывается в желудочно-кишечном тракте. Данные о выделении симетикона с грудным молоком отсутствуют.
Способ применения и дозы
Принимать по 1 капсуле 3 раза в день после приема пищи, запивая небольшим количеством воды. Максимальная суточная доза – не более 3-х капсул (360 мг).
Побочное действие
Частота побочных реакций приведена в виде следующей градации: очень часто (> 1/10); часто (> 1/100, < 1/10); нечасто (> 1/1000, < 1/100); редко (> 1/10000, < 1/1000); очень редко (< 1/10000), включая отдельные сообщения неуточненной частоты (частота не может быть подсчитана по доступным данным).
По данным пострегистрационного применения
Нарушения со стороны желудочно-кишечного тракта
Очень редко: рвота
Нарушения со стороны кожи и подкожных тканей
Очень редко: ангионевротический отек, сыпь
Передозировка
В процессе анализа данных пострегистрационного наблюдения указаний на существование симптомов передозировки не выявлено.
Взаимодействие с другими лекарственными средствами
Нет данных.
Особые указания
Если лекарственное средство пришло в негодность или истек срок годности – не выбрасывайте его в сточные воды и не выбрасывайте на улицу! Поместите лекарственное средство в пакет и положите в мусорный контейнер. Эти меры помогут защитить окружающую среду! Влияние на способность управлять автомобилем
Симетикон не влияет на способность управлять автомобилем и работу с движущимися механизмами.
Форма выпуска
Капсулы 120 мг.По 10 мягких капсул в блистере из ПВХ/ПВДХ/алюминия. По 2 блистера в картонной пачке вместе с инструкцией по медицинскому применению.
Условия хранения
Хранить при температуре не выше 25 °С.Хранить в недоступном для детей месте.
Условия отпуска
Без рецепта
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Таким образом, происходит быстрый дренаж жидкости, что способствует разрыву пленки, в следствие чего высвобождающийся газ получает возможность всасываться или выводиться естественным путем."}},{"type":"paragraph","data":{"text":"\u003cb\u003eФармакокинетика:\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Симетикон – это химически инертная субстанция, не обладающая физиологической активностью, она не всасывается, проходит через пищеварительный тракт и выводится в неизменном виде.\n\n"}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Симптоматическое лечение метеоризма, избыточного газообразования и вздутия живота, связанных с расстройствами со стороны желудочно-кишечного тракта, в том числе, с функциональной диспепсией."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к симетикону или другим компонентам препарата, детский возраст до 18 лет."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Клинические данные о воздействии симетикона при использовании во время беременности отсутствуют.Симетикон можно применять во время беременности только в том случае, если предполагаемая польза терапии для матери превосходит потенциальный риск для плода, принимая во внимание тот факт, что симетикон физиологически не активен и не всасывается в желудочно-кишечном тракте. 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Поместите лекарственное средство в пакет и положите в мусорный контейнер. Эти меры помогут защитить окружающую среду! Влияние на способность управлять автомобилем"}},{"type":"paragraph","data":{"text":"Симетикон не влияет на способность управлять автомобилем и работу с движущимися механизмами.\n\n"}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы 120 мг.По 10 мягких капсул в блистере из ПВХ/ПВДХ/алюминия. 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