Средство для внутрисуставного введения Армавискон
(далее - средство) представляет собой бесцветный вязкий раствор.
Фармакологические свойства
Средство оказывает анальгезирующее, корректирующее
действие на метаболизм костной и хрящевой ткани.
Армавискон представляет собой стерильный вязкий
раствор натриевой соли гиалуроновой кислоты (натрия гиалуроната) высокой
степени очистки, высокомолекулярный (молекулярная масса составляет не менее 3
МДа). Гиалуроновая кислота – необходимый компонент экстрацеллюлярного матрикса,
присутствует в высоких концентрациях в составе хряща и синовиальной жидкости. Гиалуроновая
кислота обеспечивает вязкость и эластичность синовиальной жидкости, а также она
необходима для формирования хряща. При остеоартрозе отмечаются дефицит и
качественные изменения гиалуроновой кислоты в составе синовиальной жидкости и
хряща. Внутрисуставное введение гиалуроновой кислоты приводит к улучшению
функционального состояния сустава. При использовании средства Армавискон при
остеоартрозе коленного сустава отмечается улучшение клинического течения
остеоартроза до шести месяцев с момента применения, наблюдается
противовоспалительный и анальгетический эффект за счет восполнения объема и
восстановления вязкости и эластичности синовиальной жидкости, которая заполняет
полость сустава и выполняет роль внутрисуставной смазки. Она предотвращает
трение суставных поверхностей, что позволяет устранить болевые ощущения и
воспаление, а также защищает от преждевременного изнашивания и разрушения
гиалинового хряща, обеспечивает подвижность, имеет амортизационные способности
(гасит внешние удары, защищая компоненты сустава от повреждения).
Раствор натрия гиалуроната распределяется местно в
полости сустава, где он подвергается локальным преобразованиям, оказывая
смазывающее действие.
Извлечение или замена средства неприменима, так как он
неотделимо смешивается с синовиальной жидкостью сустава.
Показания к применению
·
для увеличения подвижности сустава и
устранения боли, обусловленной дегенеративно-дистрофическими или
посттравматическими изменениями суставов;
·
для реабилитации после артроскопии;
·
для лечения пациентов, имеющих повышенные
физические нагрузки и регулярно нагружающих пораженный сустав.
Противопоказания
·
повышенная чувствительность к компонентам
средства;
·
наличие инфекции или повреждений кожного
покрова в области инъекции;
·
острый синовит;
·
детский возраст до 18 лет (по причине
отсутствия клинических данных).
Применение при беременности и в период грудного вскармливания
Не рекомендуется применять средство при
беременности и в период грудного вскармливания по причине отсутствия
клинических данных. Назначение средства во время беременности и в период
грудного вскармливания на усмотрение хирурга-ортопеда.
Способ применения и дозы
Внутрисуставно. В
коленный сустав содержимое одного заполненного шприца - 2 мл (20 мг)
следует вводить 1 раз в неделю, курсом из 5 инъекций по описанной ниже
стандартной методике. Обычно для коленного сустава используется игла 1,5 дюйма
21G,
для других суставов рекомендуется использовать иглу необходимого размера (от 17G до 22G) в зависимости от сустава.
Методика
введения
Средство должно вводиться только
медицинским персоналом, прошедшим специальное обучение. Режим введения в суставы и
околосуставное пространство определяется врачом индивидуально с учетом
тяжести дегенеративных или травматических изменений в суставе. Рекомендуется
выполнять инъекции в тазобедренный и др. суставы под ультразвуковым или
рентгеноскопическим контролем. Средство перед применением рекомендуется нагреть
до комнатной температуры. Вводить средство следует точно в полость сустава по
стандартным методикам, учитывая анатомические особенности. Перед введением
средства следует удалить выпот из суставной сумки. Для удаления выпота и
введения средства может использоваться одна и та же игла, однократно введенная
перед аспирацией. При этом шприц со средством присоединяется к освобожденной от
шприца игле. Для подтверждения нахождения иглы в полости сустава следует
аспирировать доступное количество синовиальной жидкости перед медленным
введением. Следует соблюдать правила асептики и антисептики при выполнении
процедуры. Введение средства в полость сустава должно быть прекращено при
появлении боли во время инъекции. При введении иглы, особенно для осуществления
инъекций в тазобедренный сустав рекомендуется применение местной анестезии. Следует
избегать попадания воздуха в шприц.
Неиспользованное
до конца средство не подлежит хранению.
Продолжительность терапевтического эффекта – до 6
месяцев. При необходимости возможно проведение повторного курса инъекций после
консультации с врачом.
Побочное действие
Возможно
возникновение умеренной болезненности, отека, повышение температуры и
покраснение в области инъекции, увеличение содержания экссудата в полости
сустава. Вышеуказанные симптомы носят преходящий характер и обычно исчезают
спустя 24 ч. При возникновении указанных симптомов рекомендуется разгрузить
пораженный сустав и приложить лед.
Крайне редко могут
наблюдаться аллергические реакции.
Взаимодействие с другими лекарственными средствами
Армавискон не следует назначать
одновременно с другими внутрисуставными инъекциями ввиду отсутствия
значительного опыта.
Не следует применять
дезинфицирующие средства, содержащие четвертичные аммониевые соединения,
поскольку гиалуроновая кислота осаждается в присутствии этих веществ.
Особые указания
Натрия гиалуронат получен путем
ферментации бактерий Streptococcus equi и тщательно очищен. Тем не менее, врач
должен учитывать потенциальный риск, связанный с инъекционным введением любых
биологических веществ.
Экстраартикулярное введение Армавискона в
капсулу сустава или синовиальные ткани не допускается. Это может вызвать
локальные побочные эффекты. Недопустимо попадание средства в кровеносные сосуды.
В течение первых 2 суток после проведения
процедуры рекомендуется не перегружать сустав, особенно следует избегать длительной
нагрузки.
Армавискон не влияет на способность
человека управлять автотранспортом, заниматься другими потенциально опасными
видами деятельности, требующими повышенной концентрации внимания и быстроты
психомоторных реакций.
Больным с воспалительными заболеваниями, в
частности, с болезнью Бехтерева и ревматоидным артритом, Армавискон не
назначают.
Не предназначен для детей.
Только для однократного применения.
В комплект может входить 2 иглы
инъекционных одноразовых стерильных для возможности выбора врачом иглы
необходимого калибра/размера в зависимости от сустава, в который будет
вводиться средство.
Обязательно обращайте внимание на срок
годности иглы, указанный на ее этикетке.
Для безопасного использования и ликвидации
использованных игл соблюдайте общегосударственные и региональные правила и
нормы.
Форма выпуска
По 2 мл в шприцы.
По 1 шприцу в
пакете или контурной ячейковой упаковке. Допускается вложение 1
или
2 игл в пакет или контурную ячейковую упаковку.
По 1 пакету или контурной ячейковой
упаковке и 1 или 2 иглы инъекционные одноразовые стерильные (если иглы не
вкладываются в пакет или контурную ячейковую упаковку) или без них или по 2
пакета или контурные ячейковые упаковки и 2 или 4 иглы инъекционные одноразовые
стерильные (если иглы не вкладываются в пакет или контурную ячейковую упаковку)
или без них вместе с инструкцией по применению в пачке из картона.
Допускается вложение игл одинакового или
различного размера. Информация о размере вложенной иглы (вложенных игл) указана
на потребительской упаковке.
18G 1 ½ (1,2×40 мм) и 21G
1 ½ (0,8×40 мм) – для коленного сустава; 18G 2 (1,2×50 мм), 21G 2 (0,8×50 мм), 18G 4 (1,2×100 мм), 21G
4 ¾ (0,8×120 мм) и 21G 4 (0,8×100 мм) – для тазобедренного сустава.
Допускается вложение в пачку из картона
этикетки слежения в количестве 3 шт.
(для 1 шприца) или 6 шт. (для 2 шприцев).
Условия хранения
Хранить при
температуре от + 2 °С до + 25 °С.
Не замораживать.
Хранить в
недоступном для детей месте.
Срок годности
3 года.
Не применять после
окончания срока годности!
Производитель
ООО «Гротекс», Россия
195279, Санкт-Петербург, Индустриальный
пр., д. 71, корп. 2, лит. А
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
Начните сравнивать цены и заказывать лекарства прямо в приложении
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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шприц, 2 шт, 2 мл, 1 %, для внутрисуставного введения","short":"Раствор, 2 шт, 2 мл, 1 %","package":"2 шт, 2 мл, 1 %"},"prescription":false,"catalog_section_id":74,"manufacturer":{"id":2347,"title":"Гротекс","slug":"groteks_2347","logo":{"isTouch":{"retina":null,"default":null},"isFromTablet":{"retina":null,"default":null}}},"is_advert":false,"product_form":"Раствор","slug":"159852-armaviskon","attributes":{"count":"2 шт","dose":"1 %","volume":"2 мл","spf":"","size":""},"image":{"isTouch":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/69609/phoneMedium_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/69609/phoneMedium_default/"},"isFromTablet":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/69609/tabletLarge_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/69609/tabletLarge_default/"}},"image_thumb":{"isTouch":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/69609/previewTouch_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/69609/previewTouch_default/"},"isFromTablet":{"retina":"https://vseapteki.ru/cropping/thumbnails/101/69609/previewDesktopMedium_retina/","default":"https://vseapteki.ru/cropping/thumbnails/101/69609/previewDesktopMedium_default/"}},"available":true,"price":{"min":"11813","max":"11813"},"counters":null,"description":{"data":[{"id":4,"name":"Состав","slug":"ingredients","body":[{"type":"paragraph","data":{"text":"\u003cb\u003eна 1 мл: \u003c/b\u003eнатрия\nгиалуронат - 9-11 мг/мл\n(1 %), натрия хлорид - 8,50 мг/мл, натрия\nгидрофосфата дигидрат - 0,28 мг/мл, натрия дигидрофосфата дигидрат - 0,044 мг/мл, вода для инъекций - до 1 мл."}},{"type":"paragraph","data":{"text":"Динамическая вязкость раствора составляет\n> 100 мПа·с, осмоляльность – 250 -\n350 мОсм/кг, рН – 6,5 - 7,5."}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Средство для внутрисуставного введения Армавискон\n(далее - средство) представляет собой бесцветный вязкий раствор."}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"Средство оказывает анальгезирующее, корректирующее\nдействие на метаболизм костной и хрящевой ткани."}},{"type":"paragraph","data":{"text":"Армавискон представляет собой стерильный вязкий\nраствор натриевой соли гиалуроновой кислоты (натрия гиалуроната) высокой\nстепени очистки, высокомолекулярный (молекулярная масса составляет не менее 3\nМДа). Гиалуроновая кислота – необходимый компонент экстрацеллюлярного матрикса,\nприсутствует в высоких концентрациях в составе хряща и синовиальной жидкости. Гиалуроновая\nкислота обеспечивает вязкость и эластичность синовиальной жидкости, а также она\nнеобходима для формирования хряща. При остеоартрозе отмечаются дефицит и\nкачественные изменения гиалуроновой кислоты в составе синовиальной жидкости и\nхряща. Внутрисуставное введение гиалуроновой кислоты приводит к улучшению\nфункционального состояния сустава. При использовании средства Армавискон при\nостеоартрозе коленного сустава отмечается улучшение клинического течения\nостеоартроза до шести месяцев с момента применения, наблюдается\nпротивовоспалительный и анальгетический эффект за счет восполнения объема и\nвосстановления вязкости и эластичности синовиальной жидкости, которая заполняет\nполость сустава и выполняет роль внутрисуставной смазки. Она предотвращает\nтрение суставных поверхностей, что позволяет устранить болевые ощущения и\nвоспаление, а также защищает от преждевременного изнашивания и разрушения\nгиалинового хряща, обеспечивает подвижность, имеет амортизационные способности\n(гасит внешние удары, защищая компоненты сустава от повреждения)."}},{"type":"paragraph","data":{"text":"Раствор натрия гиалуроната распределяется местно в\nполости сустава, где он подвергается локальным преобразованиям, оказывая\nсмазывающее действие."}},{"type":"paragraph","data":{"text":"Извлечение или замена средства неприменима, так как он\nнеотделимо смешивается с синовиальной жидкостью сустава."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"· \nдля увеличения подвижности сустава и\nустранения боли, обусловленной дегенеративно-дистрофическими или\nпосттравматическими изменениями суставов;"}},{"type":"paragraph","data":{"text":"· \nдля реабилитации после артроскопии;"}},{"type":"paragraph","data":{"text":"· \nдля лечения пациентов, имеющих повышенные\nфизические нагрузки и регулярно нагружающих пораженный сустав."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"· \nповышенная чувствительность к компонентам\nсредства;"}},{"type":"paragraph","data":{"text":"· \nналичие инфекции или повреждений кожного\nпокрова в области инъекции;"}},{"type":"paragraph","data":{"text":"· \nострый синовит;"}},{"type":"paragraph","data":{"text":"· \nдетский возраст до 18 лет (по причине\nотсутствия клинических данных)."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Не рекомендуется применять средство при\nбеременности и в период грудного вскармливания по причине отсутствия\nклинических данных. Назначение средства во время беременности и в период\nгрудного вскармливания на усмотрение хирурга-ортопеда.\u003cb\u003e\u003c/b\u003e"}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрисуставно. В\nколенный сустав содержимое одного заполненного шприца - 2 мл (20 мг)\nследует вводить 1 раз в неделю, курсом из 5 инъекций по описанной ниже\nстандартной методике. Обычно для коленного сустава используется игла 1,5 дюйма\n21G,\nдля других суставов рекомендуется использовать иглу необходимого размера (от 17G до 22G) в зависимости от сустава."}},{"type":"paragraph","data":{"text":"\u003ci\u003eМетодика\nвведения\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Средство должно вводиться только\nмедицинским персоналом, прошедшим специальное обучение. Режим введения в суставы и\nоколосуставное пространство определяется врачом индивидуально с учетом\nтяжести дегенеративных или травматических изменений в суставе. Рекомендуется\nвыполнять инъекции в тазобедренный и др. суставы под ультразвуковым или\nрентгеноскопическим контролем. Средство перед применением рекомендуется нагреть\nдо комнатной температуры. Вводить средство следует точно в полость сустава по\nстандартным методикам, учитывая анатомические особенности. Перед введением\nсредства следует удалить выпот из суставной сумки. Для удаления выпота и\nвведения средства может использоваться одна и та же игла, однократно введенная\nперед аспирацией. При этом шприц со средством присоединяется к освобожденной от\nшприца игле. Для подтверждения нахождения иглы в полости сустава следует\nаспирировать доступное количество синовиальной жидкости перед медленным\nвведением. Следует соблюдать правила асептики и антисептики при выполнении\nпроцедуры. Введение средства в полость сустава должно быть прекращено при\nпоявлении боли во время инъекции. При введении иглы, особенно для осуществления\nинъекций в тазобедренный сустав рекомендуется применение местной анестезии. Следует\nизбегать попадания воздуха в шприц."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНеиспользованное\nдо конца средство не подлежит хранению.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Продолжительность терапевтического эффекта – до 6\nмесяцев. При необходимости возможно проведение повторного курса инъекций после\nконсультации с врачом."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Возможно\nвозникновение умеренной болезненности, отека, повышение температуры и\nпокраснение в области инъекции, увеличение содержания экссудата в полости\nсустава. Вышеуказанные симптомы носят преходящий характер и обычно исчезают\nспустя 24 ч. При возникновении указанных симптомов рекомендуется разгрузить\nпораженный сустав и приложить лед."}},{"type":"paragraph","data":{"text":"Крайне редко могут\nнаблюдаться аллергические реакции."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Армавискон не следует назначать\nодновременно с другими внутрисуставными инъекциями ввиду отсутствия\nзначительного опыта."}},{"type":"paragraph","data":{"text":"Не следует применять\nдезинфицирующие средства, содержащие четвертичные аммониевые соединения,\nпоскольку гиалуроновая кислота осаждается в присутствии этих веществ."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Натрия гиалуронат получен путем\nферментации бактерий Streptococcus equi и тщательно очищен. Тем не менее, врач\nдолжен учитывать потенциальный риск, связанный с инъекционным введением любых\nбиологических веществ."}},{"type":"paragraph","data":{"text":"Экстраартикулярное введение Армавискона в\nкапсулу сустава или синовиальные ткани не допускается. Это может вызвать\nлокальные побочные эффекты. Недопустимо попадание средства в кровеносные сосуды."}},{"type":"paragraph","data":{"text":"В течение первых 2 суток после проведения\nпроцедуры рекомендуется не перегружать сустав, особенно следует избегать длительной\nнагрузки. "}},{"type":"paragraph","data":{"text":"Армавискон не влияет на способность\nчеловека управлять автотранспортом, заниматься другими потенциально опасными\nвидами деятельности, требующими повышенной концентрации внимания и быстроты\nпсихомоторных реакций."}},{"type":"paragraph","data":{"text":"Больным с воспалительными заболеваниями, в\nчастности, с болезнью Бехтерева и ревматоидным артритом, Армавискон не\nназначают."}},{"type":"paragraph","data":{"text":"Не предназначен для детей."}},{"type":"paragraph","data":{"text":"Только для однократного применения."}},{"type":"paragraph","data":{"text":"В комплект может входить 2 иглы\nинъекционных одноразовых стерильных для возможности выбора врачом иглы\nнеобходимого калибра/размера в зависимости от сустава, в который будет\nвводиться средство."}},{"type":"paragraph","data":{"text":"Обязательно обращайте внимание на срок\nгодности иглы, указанный на ее этикетке."}},{"type":"paragraph","data":{"text":"Для безопасного использования и ликвидации\nиспользованных игл соблюдайте общегосударственные и региональные правила и\nнормы."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"По 2 мл в шприцы.\u003cb\u003e\n\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"По 1 шприцу в\nпакете или контурной ячейковой упаковке. Допускается вложение 1\nили"}},{"type":"paragraph","data":{"text":"\n2 игл в пакет или контурную ячейковую упаковку."}},{"type":"paragraph","data":{"text":"По 1 пакету или контурной ячейковой\nупаковке и 1 или 2 иглы инъекционные одноразовые стерильные (если иглы не\nвкладываются в пакет или контурную ячейковую упаковку) или без них или по 2\nпакета или контурные ячейковые упаковки и 2 или 4 иглы инъекционные одноразовые\nстерильные (если иглы не вкладываются в пакет или контурную ячейковую упаковку)\nили без них вместе с инструкцией по применению в пачке из картона."}},{"type":"paragraph","data":{"text":"Допускается вложение игл одинакового или\nразличного размера. Информация о размере вложенной иглы (вложенных игл) указана\nна потребительской упаковке."}},{"type":"paragraph","data":{"text":"18G 1 ½ (1,2×40 мм) и 21G\n1 ½ (0,8×40 мм) – для коленного сустава; 18G 2 (1,2×50 мм), 21G 2 (0,8×50 мм), 18G 4 (1,2×100 мм), 21G\n4 ¾ (0,8×120 мм) и 21G 4 (0,8×100 мм) – для тазобедренного сустава."}},{"type":"paragraph","data":{"text":"Допускается вложение в пачку из картона\nэтикетки слежения в количестве 3 шт."}},{"type":"paragraph","data":{"text":"\n(для 1 шприца) или 6 шт. (для 2 шприцев)."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить при\nтемпературе от + 2 °С до + 25 °С."}},{"type":"paragraph","data":{"text":"Не замораживать."}},{"type":"paragraph","data":{"text":"Хранить в\nнедоступном для детей месте. "}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года."}},{"type":"paragraph","data":{"text":"Не применять после\nокончания срока годности!"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ООО «Гротекс», Россия"}},{"type":"paragraph","data":{"text":"195279, Санкт-Петербург, Индустриальный\nпр., д. 71, корп. 2, лит. А"}},{"type":"paragraph","data":{"text":"Тел.: +7 812 385 47 87"}},{"type":"paragraph","data":{"text":"Факс: +7 812 385 47 88"}},{"type":"paragraph","data":{"text":"\u003ca href=\"http://www.solopharm.com\"\u003ewww.solopharm.com\u003c/a\u003e"}},{"type":"paragraph","data":{"text":"www.armaviskon.ru\u003cb\u003e\u003c/b\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"Средство оказывает анальгезирующее, корректирующее действие на метаболизм костной и хрящевой ткани. 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При использовании средства Армавискон при остеоартрозе коленного сустава отмечается улучшение клинического течения остеоартроза до шести месяцев с момента применения, наблюдается противовоспалительный и анальгетический эффект за счет восполнения объема и восстановления вязкости и эластичности синовиальной жидкости, которая заполняет полость сустава и выполняет роль внутрисуставной смазки. Она предотвращает трение суставных поверхностей, что позволяет устранить болевые ощущения и воспаление, а также защищает от преждевременного изнашивания и разрушения гиалинового хряща, обеспечивает подвижность, имеет амортизационные способности (гасит внешние удары, защищая компоненты сустава от повреждения). Раствор натрия гиалуроната распределяется местно в полости сустава, где он подвергается локальным преобразованиям, оказывая смазывающее действие. 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