ФармакодинамикаФеназопиридин, выделяясь с мочой, воздействуе... Инструкция
Показания к применению
Симптоматическая терапия дизурии (в том
числе боль, жжение, учащенное мочеиспускание), вызванной раздражением слизистой
оболочки нижних мочевыводящих путей вследствие инфекций, травм, хирургических
вмешательств, эндоскопических процедур, использования зонда или катетера.
Противопоказания
- Повышенная чувствительность к феназопиридину
и/или вспомогательным веществам в составе препарата;
- нарушения функции печени (печеночная
недостаточность);
Круглые двояковыпуклые таблетки, покрытые оболочкой
коричневого цвета, на поперечном разрезе ядро коричневого цвета
с белыми вкраплениями, на воздухе краснеет.
Фармакотерапевтическая группа
другие препараты, применяемые в урологии.
Код
АТХ:
G04BХ06
Фармакологические свойства
Фармакодинамика
Феназопиридин, выделяясь с мочой,
воздействует на слизистую оболочку нижних мочевыводящих путей, где оказывает
местный анальгетический эффект. Это действие помогает уменьшить дизурические
явления в том числе: боль, жжение, учащенное мочеиспускание. Точный механизм
действия неизвестен.
Фармакокинетика
Фармакокинетические свойства
феназопиридина не были полностью изучены. Феназопиридин и его метаболиты быстро
выводятся из организма почками. На 90% в течение суток при приеме 600 мг
феназопиридина в сутки, при этом 41% в виде неизмененного препарата и 49% в
виде метаболита.
Показания к применению
Симптоматическая терапия дизурии (в том
числе боль, жжение, учащенное мочеиспускание), вызванной раздражением слизистой
оболочки нижних мочевыводящих путей вследствие инфекций, травм, хирургических
вмешательств, эндоскопических процедур, использования зонда или катетера.
Противопоказания
- Повышенная чувствительность к феназопиридину
и/или вспомогательным веществам в составе препарата;
- нарушения функции печени (печеночная
недостаточность);
- почечная недостаточность;
- анемия и метгемоглобинемия;
- период грудного вскармливания
(безопасность не установлена);
- беременность;
- возраст до 18 лет.
Если
у Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска,
перед применением препарата необходимо проконсультироваться с врачом.
С осторожностью
- Дефицит глюкозо-6-фосфатдегидрогеназы;
- сердечная недостаточность;
- нервно-мышечные заболевания;
- возраст старше 65 лет (отсутствие опыта
применения).
Если
у Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска,
перед применением препарата необходимо проконсультироваться с врачом.
Применение при беременности и в период грудного вскармливания
Беременность
В доклинических
исследованиях на животных данных о наличии тератогенного действия
феназопиридина не получено (при введении с сульфацитином крысам в дозе до 110 мг/кг/сут
и кроликам в дозе до 39 мг/кг/сут). Тем не менее, в связи с отсутствием
клинических исследований безопасности применения феназопиридина у беременных и
его способностью проникать через плацентарный барьер при беременности, применение
феназопиридина во время беременности противопоказано.
Период грудного
вскармливания
Нет данных о проникновении феназопиридина
в грудное молоко человека. Применение феназопиридина в период грудного
вскармливания противопоказано.
Способ применения и дозы
Режим дозирования препарата
По 2
таблетки (200 мг) 3 раза в сутки. Длительность лечения не более 2 дней (в том
числе, в сочетании с антибактериальными препаратами).
В случае пропуска приема препарата Феназалгин,
таблетки следует принять сразу, как только пациент вспомнит об этом. Если
пациент вспомнил о пропуске приема таблеток непосредственно перед приемом
следующей дозы, двойную дозу препарата принимать не следует.
Применение препарата в
особых клинических группах
Дети и подростки до 18
лет
Применение препарата Феназалгин у детей и
подростков до 18 лет противопоказано.
У пациентов с нарушениями функции почек
Применение препарата Феназалгин у пациентов с почечной недостаточностью противопоказано.
У пациентов с нарушениями
функции печени
Применение препарата Феназалгин у пациентов с печеночной недостаточностью противопоказано.
Способ применения
Внутрь, во время или после приема
пиши, запивая полным стаканом воды. Таблетки принимают целиком, не разжевывая.
Для достижения
оптимальных результатов препарат Феназалгин следует принимать, строго выполняя
все рекомендации, изложенные в инструкции по применению. При отсутствии
положительного эффекта от проводимой в течение 2 дней терапии препаратом или
ухудшении состояния, или появления новых симптомов следует обратиться к врачу.
Применяйте препарат
только согласно тем показаниям, тому способу применения и в тех дозах, которые
указаны в инструкции.
Побочное действие
В соответствии с
классификацией Всемирной организации здравоохранения (ВОЗ) нежелательные
реакции представлены в соответствии с частотой их развития: очень часто
(≥ 1/10); часто (≥ 1/100, < 1/10), нечасто (≥ 1/1000, < 1/100), редко (≥ 1/10000,
< 1/1000) и очень редко (< 1/10000), частота неизвестна – по имеющимся
данным установить частоту возникновения не представлялось возможным.
Нарушения
со стороны крови и
лимфатической системы:частота неизвестна – метгемоглобинемия,
гемолитическая анемия (при дефиците глюкозо-6-фосфатдегидрогеназы),
сульфогемоглобинемия, нейропения, лейкопения, панцитопения.
Нарушения со стороны иммунной системы: редко
– кожная сыпь, зуд, лихорадка и другие реакции гиперчувствительности; очень
редко – бронхоспазм; частота
неизвестна – анафилактоидная реакция.
Нарушения со стороны нервнойсистемы:
редко – головная боль, головокружение, асептический менингит.
Нарушения со стороны
органа слуха и лабиринтные нарушения
Частота неизвестна – боль в ушах.
Нарушения со стороны желудочно-кишечного
тракта: редко– тошнота, рвота, диарея,
окрашивание каловых масс в оранжево-красный цвет.
Нарушения со стороны печени и желчевыводящих
путей: очень редко – острая гепатотоксичность (связанная с
передозировкой лекарственного препарата), желтуха, частота неизвестна – аллергический
гепатит.
Нарушения со стороны кожи
и подкожных тканей
Очень редко (при
длительном применении) – изменение пигментации кожи и склер с окрашиванием в
желтоватый цвет; частота
неизвестна – пожелтение ногтей.
Нарушения
со стороны почек и мочевыводящих путей: редко –
окрашивание мочи в темно-оранжевый или красноватый цвет; частота неизвестна – уронефролитиаз,
острая нефротоксичность (связанная с передозировкой лекарственного препарата).
Общие расстройства и нарушения в месте
введения
Очень редко (при длительном применении) –
отек лица, верхних и нижних конечностей.
Превышение рекомендованной дозы феназопиридина
(особенно у пациентов со сниженной функцией почек, а также у пожилых пациентов)
может привести к повышению его концентрации в сыворотке крови и развитию
токсических реакций.
Симптомы: метгемоглобинемия
(особенно у пациентов с дефицитом глюкозо-6-фосфатдегидрогеназы),
нефро- и гепатоксические проявления, а также усиление выраженности других
нежелательных реакций препарата.
В случае передозировки препарата
Феназалгин следует немедленно обратиться к врачу. Лечение: прекратить
прием препарата, вызвать рвоту и провести другие мероприятия, направленные на
выведение феназопиридина из организма, а также симптоматическая терапия. Для
устранения метгемоглобинемии и связанных с ней симптомов целесообразно
внутривенное введение 1% раствора метиленового синего (1-2 мг/кг).
Взаимодействие с другими лекарственными средствами
При одновременном приеме феназопиридин может
увеличивать биодоступность ципрофлоксацина. Сведения о других взаимодействиях с
лекарственными препаратами отсутствуют.
При необходимости феназопиридин может
назначаться совместно с антибактериальными препаратами.
Если
Вы применяете нижеперечисленные или другие лекарственные препараты (в том числе
безрецептурные) перед применением препарата Феназалгин проконсультируйтесь с врачом.
Особые указания
Применение феназопиридина для снятия
симптомов дизурии вследствие инфекции не должно задерживать постановку диагноза
и начала патогенетической терапии. Препарат следует применять для
симптоматического облегчения боли, а не для замены специфической антибактериальной
терапии.
У пациентов с дефицитом
глюкозо-6-фосфатдегидрогеназы прием феназопиридина может приводить к гемолизу
эритроцитов и развитию метгемоглобинемии.
При применении феназопиридина
возможно окрашивание мочи (при щелочной реакции) в темно-оранжевый или
красноватый цвет и каловых масс в оранжево-красный цвет.
Желтоватый цвет кожи или склер может
указывать на накопление феназопиридина в результате нарушения функции почек или
передозировки или приема препарата более 2 дней, что требует прекращения приема
препарата.
Следует исключить ношение контактных
линз, так как феназопиридин может вызывать окрашивание контактных линз.
Лечение феназопиридином не должно
превышать 2 дней. 2,3,6-триаминопиридин (один из метаболитов феназопиридина) в
токсикологических исследованиях продемонстрировал способность повреждать клетки
поперечно-полосатых мышц и кардиомиоциты. Рекомендуется соблюдать осторожность
при применении феназопиридина у пациентов с заболеванием сердца и
нервно-мышечными заболеваниями.
Феназопиридин противопоказан пациентам
с любыми заболеваниями печени.
Феназопиридин противопоказан
пациентам с почечной недостаточностью. Следует иметь в виду возможность
снижения функции почек, связанное с возрастом. Данные о применении
феназопиридина у пациентов старше 65 лет, в том числе с нарушением функции
почек отсутствуют.
Феназопиридин может вызывать
изменения результатов анализов мочи, проводимых колориметрическими, фотометрическими
и флуориметрическими методами (определение кетоновых тел, порфиринов,
уробилиногена).
Влияние на способность управлять автомобилем и движущимися механизмами
Следует принимать во внимание
потенциальную возможность развития такой нежелательной реакции, как
головокружение. При появлении головокружения следует воздержаться от управления
транспортными средствами и механизмами.
Форма выпуска
Таблетки, покрытые
пленочной оболочкой, 100 мг.
По 6 или 7, или 10
таблеток в контурной ячейковой упаковке из пленки поливинилхлоридной и фольги
алюминиевой.
По 1, 2, 3, 4 или 5
контурных ячейковых упаковок вместе с инструкцией по применению помещают в
пачку из картона.
Условия хранения
Хранить в защищенном от света месте,
при температуре не выше 30 °С. Хранить в недоступном для
детей месте!
Срок годности
5 лет.
Не применять по истечении срока годности,
указанного на упаковке.
Условия отпуска
Отпускают без рецепта.
Производитель
ЗАО «Обнинская химико-фармацевтическая
компания» (ЗАО «ОХФК»)
Адрес места производства: Россия, Калужская
обл., г. Обнинск, Киевское шоссе, зд. 103, зд. 107
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на воздухе краснеет."}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"другие препараты, применяемые в урологии. "}},{"type":"paragraph","data":{"text":"\u003cb\u003eКод\nАТХ\u003c/b\u003e:\nG04BХ06"}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003eФармакодинамика\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Феназопиридин, выделяясь с мочой,\nвоздействует на слизистую оболочку нижних мочевыводящих путей, где оказывает\nместный анальгетический эффект. Это действие помогает уменьшить дизурические\nявления в том числе: боль, жжение, учащенное мочеиспускание. Точный механизм\nдействия неизвестен."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003eФармакокинетика\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"Фармакокинетические свойства\nфеназопиридина не были полностью изучены. Феназопиридин и его метаболиты быстро\nвыводятся из организма почками. На 90% в течение суток при приеме 600 мг\nфеназопиридина в сутки, при этом 41% в виде неизмененного препарата и 49% в\nвиде метаболита."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Симптоматическая терапия дизурии (в том\nчисле боль, жжение, учащенное мочеиспускание), вызванной раздражением слизистой\nоболочки нижних мочевыводящих путей вследствие инфекций, травм, хирургических\nвмешательств, эндоскопических процедур, использования зонда или катетера."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"- Повышенная чувствительность к феназопиридину\nи/или вспомогательным веществам в составе препарата;"}},{"type":"paragraph","data":{"text":"- нарушения функции печени (печеночная\nнедостаточность);"}},{"type":"paragraph","data":{"text":"- почечная недостаточность;"}},{"type":"paragraph","data":{"text":"- анемия и метгемоглобинемия;"}},{"type":"paragraph","data":{"text":"- период грудного вскармливания\n(безопасность не установлена);"}},{"type":"paragraph","data":{"text":"- беременность;"}},{"type":"paragraph","data":{"text":"- возраст до 18 лет."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли\nу Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска,\nперед применением препарата необходимо проконсультироваться с врачом.\u003c/i\u003e"}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"- Дефицит глюкозо-6-фосфатдегидрогеназы;"}},{"type":"paragraph","data":{"text":"- сердечная недостаточность;"}},{"type":"paragraph","data":{"text":"- нервно-мышечные заболевания;"}},{"type":"paragraph","data":{"text":"- возраст старше 65 лет (отсутствие опыта\nприменения)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли\nу Вас есть одно из перечисленных выше заболеваний/состояний или факторов риска,\nперед применением препарата необходимо проконсультироваться с врачом.\u003c/i\u003e"}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eБеременность\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"В доклинических\nисследованиях на животных данных о наличии тератогенного действия\nфеназопиридина не получено (при введении с сульфацитином крысам в дозе до 110 мг/кг/сут\nи кроликам в дозе до 39 мг/кг/сут). 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Длительность лечения не более 2 дней (в том\nчисле, в сочетании с антибактериальными препаратами)."}},{"type":"paragraph","data":{"text":"В случае пропуска приема препарата Феназалгин,\nтаблетки следует принять сразу, как только пациент вспомнит об этом. Если\nпациент вспомнил о пропуске приема таблеток непосредственно перед приемом\nследующей дозы, двойную дозу препарата принимать не следует."}},{"type":"paragraph","data":{"text":"\u003cb\u003e\u003ci\u003eПрименение препарата в\nособых клинических группах\u003c/i\u003e\u003c/b\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eДети и подростки до 18\nлет\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Применение препарата Феназалгин у детей и\nподростков до 18 лет противопоказано."}},{"type":"paragraph","data":{"text":"\u003ci\u003eУ пациентов с нарушениями функции почек\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Применение препарата Феназалгин у пациентов с почечной недостаточностью противопоказано."}},{"type":"paragraph","data":{"text":"\u003ci\u003eУ пациентов с нарушениями\nфункции печени\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Применение препарата Феназалгин у пациентов с печеночной недостаточностью противопоказано."}},{"type":"paragraph","data":{"text":"Способ применения"}},{"type":"paragraph","data":{"text":"Внутрь, во время или после приема\nпиши, запивая полным стаканом воды. Таблетки принимают целиком, не разжевывая."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДля достижения\nоптимальных результатов препарат Феназалгин следует принимать, строго выполняя\nвсе рекомендации, изложенные в инструкции по применению. При отсутствии\nположительного эффекта от проводимой в течение 2 дней терапии препаратом или\nухудшении состояния, или появления новых симптомов следует обратиться к врачу.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eПрименяйте препарат\nтолько согласно тем показаниям, тому способу применения и в тех дозах, которые\nуказаны в инструкции.\u003c/i\u003e"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"В соответствии с\nклассификацией Всемирной организации здравоохранения (ВОЗ) нежелательные\nреакции представлены в соответствии с частотой их развития: очень часто\n(≥ 1/10); часто (≥ 1/100, < 1/10), нечасто (≥ 1/1000, < 1/100), редко (≥ 1/10000,\n< 1/1000) и очень редко (< 1/10000), частота неизвестна – по имеющимся\nданным установить частоту возникновения не представлялось возможным."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны \u003c/i\u003e\u003ci\u003eкрови и\nлимфатической системы:\u003cb\u003e \u003c/b\u003e\u003c/i\u003eчастота неизвестна – метгемоглобинемия,\nгемолитическая анемия (при дефиците глюкозо-6-фосфатдегидрогеназы),\nсульфогемоглобинемия, нейропения, лейкопения, панцитопения."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны иммунной системы: \u003c/i\u003eредко\n– кожная сыпь, зуд, лихорадка и другие реакции гиперчувствительности; очень\nредко – бронхоспазм; частота\nнеизвестна – анафилактоидная реакция."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны нервной\u003c/i\u003e \u003ci\u003eсистемы\u003c/i\u003e:\nредко – головная боль, головокружение, асептический менингит."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны\nоргана зрения\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Частота неизвестна – нарушение зрения, раздражение глаз,\nобратимая потеря цветового зрения."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны\nоргана слуха и лабиринтные нарушения\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Частота неизвестна – боль в ушах."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны желудочно-кишечного\nтракта: \u003c/i\u003eредко\u003ci\u003e \u003c/i\u003e– тошнота, рвота, диарея,\nокрашивание каловых масс в оранжево-красный цвет."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны печени и желчевыводящих\nпутей: \u003c/i\u003eочень редко – острая гепатотоксичность (связанная с\nпередозировкой лекарственного препарата), желтуха, частота неизвестна – аллергический\nгепатит."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны кожи\nи подкожных тканей\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Очень редко (при\nдлительном применении) – изменение пигментации кожи и склер с окрашиванием в\nжелтоватый цвет; частота\nнеизвестна – пожелтение ногтей."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны почек и мочевыводящих путей: \u003c/i\u003eредко –\nокрашивание мочи в темно-оранжевый или красноватый цвет; частота неизвестна – уронефролитиаз,\nострая нефротоксичность (связанная с передозировкой лекарственного препарата)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eОбщие расстройства и нарушения в месте\nвведения \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Очень редко (при длительном применении) –\nотек лица, верхних и нижних конечностей."}},{"type":"paragraph","data":{"text":"\u003ca\u003e\u003ci\u003eЕсли любые из указанных в инструкции нежелательных реакций усугубляются,\nили Вы заметили любые другие нежелательные реакции, не указанные в инструкции,\nсообщите об этом врачу\u003c/i\u003e\u003c/a\u003e."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Превышение рекомендованной дозы феназопиридина\n(особенно у пациентов со сниженной функцией почек, а также у пожилых пациентов)\nможет привести к повышению его концентрации в сыворотке крови и развитию\nтоксических реакций."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы\u003c/i\u003e: метгемоглобинемия\n(особенно у пациентов с дефицитом глюкозо-6-фосфатдегидрогеназы),\nнефро- и гепатоксические проявления, а также усиление выраженности других\nнежелательных реакций препарата."}},{"type":"paragraph","data":{"text":"В случае передозировки препарата\nФеназалгин следует немедленно обратиться к врачу. \u003ci\u003eЛечение\u003c/i\u003e: прекратить\nприем препарата, вызвать рвоту и провести другие мероприятия, направленные на\nвыведение феназопиридина из организма, а также симптоматическая терапия. Для\nустранения метгемоглобинемии и связанных с ней симптомов целесообразно\nвнутривенное введение 1% раствора метиленового синего (1-2 мг/кг)."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"При одновременном приеме феназопиридин может\nувеличивать биодоступность ципрофлоксацина. Сведения о других взаимодействиях с\nлекарственными препаратами отсутствуют."}},{"type":"paragraph","data":{"text":"При необходимости феназопиридин может\nназначаться совместно с антибактериальными препаратами."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли\nВы применяете нижеперечисленные или другие лекарственные препараты (в том числе\nбезрецептурные) перед применением препарата Феназалгин проконсультируйтесь с врачом.\u003c/i\u003e"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Применение феназопиридина для снятия\nсимптомов дизурии вследствие инфекции не должно задерживать постановку диагноза\nи начала патогенетической терапии. Препарат следует применять для\nсимптоматического облегчения боли, а не для замены специфической антибактериальной\nтерапии."}},{"type":"paragraph","data":{"text":"У пациентов с дефицитом\nглюкозо-6-фосфатдегидрогеназы прием феназопиридина может приводить к гемолизу\nэритроцитов и развитию метгемоглобинемии."}},{"type":"paragraph","data":{"text":"При применении феназопиридина\nвозможно окрашивание мочи (при щелочной реакции) в темно-оранжевый или\nкрасноватый цвет и каловых масс в оранжево-красный цвет."}},{"type":"paragraph","data":{"text":"Желтоватый цвет кожи или склер может\nуказывать на накопление феназопиридина в результате нарушения функции почек или\nпередозировки или приема препарата более 2 дней, что требует прекращения приема\nпрепарата."}},{"type":"paragraph","data":{"text":"Следует исключить ношение контактных\nлинз, так как феназопиридин может вызывать окрашивание контактных линз."}},{"type":"paragraph","data":{"text":"Лечение феназопиридином не должно\nпревышать 2 дней. 2,3,6-триаминопиридин (один из метаболитов феназопиридина) в\nтоксикологических исследованиях продемонстрировал способность повреждать клетки\nпоперечно-полосатых мышц и кардиомиоциты. Рекомендуется соблюдать осторожность\nпри применении феназопиридина у пациентов с заболеванием сердца и\nнервно-мышечными заболеваниями."}},{"type":"paragraph","data":{"text":"Феназопиридин противопоказан пациентам\nс любыми заболеваниями печени."}},{"type":"paragraph","data":{"text":"Феназопиридин противопоказан\nпациентам с почечной недостаточностью. Следует иметь в виду возможность\nснижения функции почек, связанное с возрастом. Данные о применении\nфеназопиридина у пациентов старше 65 лет, в том числе с нарушением функции\nпочек отсутствуют."}},{"type":"paragraph","data":{"text":"Феназопиридин может вызывать\nизменения результатов анализов мочи, проводимых колориметрическими, фотометрическими\nи флуориметрическими методами (определение кетоновых тел, порфиринов,\nуробилиногена)."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Следует принимать во внимание\nпотенциальную возможность развития такой нежелательной реакции, как\nголовокружение. При появлении головокружения следует воздержаться от управления\nтранспортными средствами и механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, покрытые\nпленочной оболочкой, 100 мг."}},{"type":"paragraph","data":{"text":"По 6 или 7, или 10\nтаблеток в контурной ячейковой упаковке из пленки поливинилхлоридной и фольги\nалюминиевой. "}},{"type":"paragraph","data":{"text":"По 1, 2, 3, 4 или 5\nконтурных ячейковых упаковок вместе с инструкцией по применению помещают в\nпачку из картона."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в защищенном от света месте,\nпри температуре не выше 30 °С. Хранить в недоступном для\nдетей месте!"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"5 лет."}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности,\nуказанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают без рецепта. "}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ЗАО «Обнинская химико-фармацевтическая\nкомпания» (ЗАО «ОХФК»)"}},{"type":"paragraph","data":{"text":"Адрес места производства: Россия, Калужская\nобл., г. Обнинск, Киевское шоссе, зд. 103, зд. 107"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"АО «Нижфарм», Россия"}},{"type":"paragraph","data":{"text":"603105, г. Нижний\nНовгород, ул. Салганская, д. 7"}},{"type":"paragraph","data":{"text":"Тел.: (831) 278-80-88;\nфакс: (831) 430-72-28"}},{"type":"paragraph","data":{"text":"E-mail: \u003ca href=\"mailto:med@stada.ru\"\u003emed@stada.ru\u003c/a\u003e"}}]}],"source":null},"description_toggle":false,"short_description":"ФармакодинамикаФеназопиридин, выделяясь с мочой, воздействует на слизистую оболочку нижних мочевыводящих путей, где оказывает местный анальгетический эффект. Это действие помогает уменьшить дизурические явления в том числе: боль, жжение, учащенное мочеиспускание. Точный механизм действия неизвестен.ФармакокинетикаФармакокинетические свойства феназопиридина не были полностью изучены. Феназопиридин и его метаболиты быстро выводятся из организма почками. На 90% в течение суток при приеме 600 мг феназопиридина в сутки, при этом 41% в виде неизмененного препарата и 49% в виде метаболита.","substance":[{"id":2344,"title":"феназопиридина гидрохлорид","title_latin":"Phenazopyridine hydrochloride","slug":"fenazopiridina_gidrohlorid"}],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":false,"comments":null,"image_alt":"Феназалгин - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/89137/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/89137/share_default/"}},"diseases":[],"other_packages":[],"other_product_forms":[],"related_products":{"title":"Похожие товары","type":"nondrugs","products":[{"id":100406,"title":"Фурадонин Авексима","subtitle":{"full":"Таблетки, 10 шт, 50 мг, для приема внутрь","short":"Таблетки, 10 шт, 50 мг","package":"10 шт, 50 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