Ксилометазолин относится к группе местных сосудосуживающих средств (деконгестантов) с альфа2-адреномиметическим действием. Оказывает быстрое, выраженное и продолжительное сосудосуживающее действие в отношении сосудов слизистой оболочки полости носа, устраняя, таким образом, ее отечность и гиперемию. Восстанавливает проходимость носовых ходов, облегчает носовое дыхание при ринитах.
В терапевтических концентрациях не раздражает слизистую оболочку полости носа, не вызывает гиперемию. Действие наступает через несколько минут и продолжается в течение 10-12 ч.
Показания к применению
острые респираторные заболевания с явлениями ринита (насморка);
острый аллергический ринит;
поллиноз;
синусит;
евстахиит;
средний отит (для уменьшения отека слизистой оболочки носоглотки);
подготовка больного к диагностическим манипуляциям в носовых ходах.
Противопоказания
повышенная чувствительность к ксилометазолину или любому другому компоненту препарата;
воспалительные заболевания кожи или слизистой оболочки преддверия носа;
артериальная гипертензия;
тахикардия;
выраженный атеросклероз;
глаукома;
атрофический ринит;
гипертиреоз;
хирургические вмешательства на мозговых оболочках (в анамнезе); состояния после трансфеноидальной гипофизэктомии;
детский возраст до 2 лет - для Ксилокт®-СОЛОфарм, спрей назальный дозированный 35 мкг/доза;
детский возраст до 6 лет - для Ксилокт®-СОЛОфарм, спрей назальный дозированный 140 мкг/доза;
беременность;
не применять при терапии ингибиторами МАО (включая период 14 дней после их отмены), трициклическими и тетрациклическими антидепрессантами, другими местными сосудосуживающими средствами (деконгестантами), а также другими препаратами, повышающими АД.
С осторожностью
Сахарный диабет, гиперплазия предстательной железы, ИБС (стенокардия), феохромоцитома, гипертиреоз, период лактации; при повышенной чувствительности к адренергическим препаратам, сопровождающейся бессонницей, головокружением, аритмией, тремором, повышением АД.
Применение при беременности и в период грудного вскармливания
Противопоказано применение препарата при беременности.
Возможно применение препарата в период грудного вскармливания по назначению лечащего врача, если ожидаемый лечебный эффект у матери превышает риск развития возможных побочных эффектов у ребенка.
Способ применения и дозы
Интраназально (в каждый носовой ход).
Детям в возрасте от 2 до 6 лет: по 1 впрыскиванию Ксилокт®-СОЛОфарм, спрей назальный дозированный 35 мкг/доза в каждый носовой ход; не следует применять более 3 раз/сут.
Взрослым и детям старше 6 лет: по 1 впрыскиванию Ксилокт®-СОЛОфарм, спрей назальный дозированный 140 мкг/доза в каждый носовой ход (при необходимости можно повторить); не следует применять более 3 раз/сут.
Если симптомы усиливаются или улучшение не наступает в течение 3 дней, необходимо проконсультироваться с врачом. В рекомендованной дозе без консультации с врачом применять не более 7 дней.
Дозы выше рекомендованных можно применять только под наблюдением врача.
При частом и длительном использовании препарата ощущение заложенности носа может появиться вновь или ухудшиться. При появлении этих симптомов следует прекратить лечение и обратиться к врачу.
Одно впрыскивание объемом 70 мкл содержит 35 мкг ксилометазолина гидрохлорида – для Ксилокт®-СОЛОфарм, спрей назальный дозированный 35 мкг/доза.
Одно впрыскивание объемом 140 мкл содержит 140 мкг ксилометазолина гидрохлорида – для Ксилокт®-СОЛОфарм, спрей назальный дозированный 140 мкг/доза.
Побочное действие
Местные реакции: при частом и/или длительном применении – раздражение и/или сухость слизистой оболочки носоглотки, жжение, покалывание, чиханье, гиперсекреция слизистой оболочки носоглотки, реакции гиперчувствительности, отек слизистой оболочки полости носа,
Системные реакции: при частом и/или длительном применении – ощущение сердцебиения, тахикардия, аритмия, повышение АД, головная боль, тошнота, рвота, бессонница, нарушение зрения, депрессия (при длительном применении высоких доз).
Если любые из указанных выше побочных эффектов усугубляются или пациент заметил любые другие побочные эффекты, он должен сообщить об этом врачу.
Передозировка
Симптомы: усиление побочных эффектов (дозозависимых), снижение температуры тела, спутанность сознания. При случайном приеме внутрь препарат может вызывать: сильное головокружение, повышенное потоотделение, головную боль, брадикардию, повышение артериального давления, угнетение дыхания, кому и судороги. После повышения АД может наблюдаться его резкое снижение.
Лечение: симптоматическое
Взаимодействие с другими лекарственными средствами
Ксилометазолин не следует применять у пациентов, получающих терапию ингибиторами МАО и трициклическими антидепрессантами (включая период 14 дней после их отмены) в связи с возможностью повышения АД.
Особые указания
Избегать попадания препарата в глаза.
Во избежание распространения инфекции необходимо применять препарат индивидуально.
Не следует превышать рекомендованные дозы и применять препарат в течение длительного (более 7 дней) времени.
Длительное применение препарата может вызвать эффект рикошета (медикаментозный ринит), повышается риск возникновения реактивной гиперемии и атрофии слизистой оболочки носа.
Т.к. препарат содержит в составе бензалкония хлорид, в качестве консерванта, особенно при длительном применении (более 7 дней), может развиться отек слизистой оболочки полости носа. При появлении подозрений на подобную реакцию (заложенность носа), необходимо, по возможности, применять лекарственное средство, не содержащее консерванты. Если такие лекарственные средства отсутствуют, необходимо применять другую лекарственную форму.
Влияние на способность к управлению транспортными средствами и механизмами
Ксилометазолин может влиять на способность управлять транспортными средствами или оборудованием.
При лечении препаратом необходимо соблюдать осторожность при управлении транспортными средствами и занятиями другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций.
Условия хранения
Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С.
Срок годности
Срок годности - 2 года. Не применять после окончания срока годности.
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В рекомендованной дозе без консультации с врачом применять не более 7 дней."}},{"type":"paragraph","data":{"text":"Дозы выше рекомендованных можно применять только под наблюдением врача."}},{"type":"paragraph","data":{"text":"При частом и длительном использовании препарата ощущение заложенности носа может появиться вновь или ухудшиться. 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При случайном приеме внутрь препарат может вызывать: сильное головокружение, повышенное потоотделение, головную боль, брадикардию, повышение артериального давления, угнетение дыхания, кому и судороги. 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При появлении подозрений на подобную реакцию (заложенность носа), необходимо, по возможности, применять лекарственное средство, не содержащее консерванты. 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