Назначениестенокардия, артериальная гипертензия, стенокардия ПринцметалаПоказания к применению- Артериальная гипертензия (монотерапия или в комбинации с другими гипотензивными средствами);- стенокардия напряжения, вазоспастическая стенокардия (стенокардия Принцметала или вариантная стенокардия) как в монотерапии, так и в сочетании с другими антиангинальными средствами.Противопоказания- Повышенная чувствительность к амлодипину и другим производным дигидропиридина, а также вспомогательным веществам, входящим в состав препарата;- тяжелая артериальная гипотензия (систолическое АД менее 90 мм рт. сг.);- коллапс;- шок, включая кардиогенный;- обструкция выносящего тракта левого желудочка (включая тяжелый аортальный стеноз);- гемодинамически нестабильная сердечная недостаточность после инфаркта миокарда;- возраст до 18 лет (эффективность и безопасность не установлены);- дефицит лактазы, непереносимость лактозы, синдром глюкозо-галактозной мальабсорбции.С осторожностью:- Нарушение функции печени;- синдром слабости синусового узла (выраженная брадикардия, тахикардия);- ХСН неишемической этиологии III-IV функционального класса по классификации NYHA;- нестабильная стенокардия;- мягкая или умеренная степень артериальной гипотензии;- аортальный стеноз, митральный стеноз;- гипертрофическая обструктивная кардиомиопатия;- острый инфаркт миокарда (и в течение 1 месяца после перенесенного острого инфаркта миокарда);- одновременный прием ингибиторов или индукторов изофермента CYP3A4.
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