Препарат относится к противомикробным и противопротозойпым с... Инструкция
Показания к применению
дизентерия;
парагифы;
пищевая токсикоинфекция;
лямблиоз.
Противопоказания
Беременность, лактация. Повышенная индивидуальная чувствительность к группе нитрофуранов. Терминальная стадия хронической почечной недостаточности, дефицит глюкозо-6-дегидрогеназы, возраст до 1 года.
Инструкция
Регистрационный номер
ЛС-000577
Торговое название препарата
Фуразолидон
Лекарственная форма
таблетки
Состав
одна таблетка содержит 0,05 г фуразолидона и вспомогательные вещества: сахар молочный, крахмал картофельный, аэросил, кальция стеарат.
Описание
таблетки желтого или зеленовато-желтого цвета, плоскоцилиндрические, с фаской.
Фармакотерапевтическая группа
противомикробное и противопротозойное средство
Фармакологические свойства
Фармакодинамика:
Препарат относится к противомикробным и противопротозойпым средствам. Обладает бактериостатическим действием по отношению к микробам. Механизм действия заключается в нарушении активности некоторых ферментных систем бактерий. Спектр действия: грамположительные кокки (Streptococcus, Staphylococcus), грамотрицательные палочки (Escherichia, Salmonella, Shigella, Proteus, Klebsiella, Enterobacter), простейшие (Lamblia). Из возбудителей кишечных инфекций наиболее чувствительны возбудители дизентерии, брюшного тифа и паратифов. Устойчивость развивается медленно.
Фармакокинетика:
При пероральном применении фуразолидон слабо всасывается и инактивируется в кишечнике. Только около 5% препарата выводится из организма с мочой в неизмененном виде или в виде метаболитов, при этом окрашивая мочу в коричневый цвет.
Показания к применению
дизентерия;
парагифы;
пищевая токсикоинфекция;
лямблиоз.
Противопоказания
Беременность, лактация. Повышенная индивидуальная чувствительность к группе нитрофуранов. Терминальная стадия хронической почечной недостаточности, дефицит глюкозо-6-дегидрогеназы, возраст до 1 года.
Применение при беременности и в период грудного вскармливания
Противопоказан при беременности и в период лактации.
Способ применения и дозы
Фуразолидон назначают внутрь.
Для лечения паратифа, дизентерии, пищевых токсикоинфекций взрослые принимают по 0,1-0,15 г после еды 4 раза в сутки на протяжении 5-10 дней (продолжительность приема зависит от характера и тяжести патологического процесса). В таких же дозах фуразолидон можно принимать циклами по 3-6 дней (интервалы - 3-4 дня).
Дозы для детей - 10 мг/кг массы тела в сутки (суточную дозу распределяют на 3-4 приема).
Фуразолидон не рекомендуется назначать более 10 дней.
При лечении лямблиоза взрослые принимают по 0,1 г фуразолидона 4 раза в день, дети - в дозе 10 мг/кг массы тела в сутки (суточную дозу распределяют на 3-4 приема).
Высшие суточные дозы для взрослых для приема внутрь : разовая - 0,2 г, суточная - 0,8 г.
Побочное действие
Возможно появление тошноты, рвоты, снижение аппетита; в отдельных случаях могут развиться аллергические реакции.
Для уменьшения побочных реакций при применении фуразолидона рекомендуется принимать его перед едой и запивать препарат большим количеством жидкости, при необходимости уменьшить дозу, назначить антигистаминные препараты и витамины группы В. При выраженных побочных явлениях необходимо прекратить применение препарата.
Передозировка
Симптомы: острый токсический гепатит, гематотоксичность, нейротоксичность (полиневрит). Лечение: отмена ЛС, прием большого количества жидкости, симптоматическая терапия, антигистаминные ЛС, витамины группы В.
Взаимодействие с другими лекарственными средствами
Фуразолидон является ингибитором моноаминоксидазы; при его применении должны соблюдаться такие же меры предосторожности, как при применении других ингибиторов моноаминоксидазы.
Аминогликозиды и тетрациклины усиливают противомикробные свойства фуразолидона. Сенсибилизирует организм к алкоголю.
Фуразолидон увеличивает угнетение кроветворения на фоне хлорамфеникола и ристомицина.
Особые указания
Ограничен к применению при хронической почечной недостаточности, заболеваниях нервной системы. Для профилактики невритов при длительном применении нужно сочетать с витаминами группы B.
Фурозолидон обладает способностью сенсибилизировать организм к действию алкоголя и может быть использован для лечения хронического алкоголизма при недостаточной эффективности других лекарственных средств или наличии противопоказаний к их применению.
Следует учитывать, что Фуразолидон является ингибитором МАО, поэтому при его применении должны соблюдаться такие же меры предосторожности, как и при использовании классических ингибиторов МАО.
Форма выпуска
Таблетки по 50 мг.
Условия хранения
В сухом, защищенном от света, недоступном для детей месте, при температуре от 4 5 до + 30°С.
Срок годности
3 года. Препарат следует использовать до даты, указанной на упаковке.
Условия отпуска
По рецепту
Производитель
Открытое акционерное общество "Борисовский завод медицинских препаратов" (ОАО "БЗМП"), 222518, Минская обл., г. Борисов, ул. Чапаева, д. 64, Республика Беларусь
Организация, принимающая претензии потребителей
ОАО "БЗМП"
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
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Только около 5% препарата выводится из организма с мочой в неизмененном виде или в виде метаболитов, при этом окрашивая мочу в коричневый цвет."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"list","data":{"style":"ordered","items":["дизентерия;","парагифы;","пищевая токсикоинфекция;","лямблиоз."]}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Беременность, лактация. Повышенная индивидуальная чувствительность к группе нитрофуранов. Терминальная стадия хронической почечной недостаточности, дефицит глюкозо-6-дегидрогеназы, возраст до 1 года."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Противопоказан при беременности и в период лактации."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Фуразолидон назначают внутрь."}},{"type":"paragraph","data":{"text":"Для лечения паратифа, дизентерии, пищевых токсикоинфекций взрослые принимают по 0,1-0,15 г после еды 4 раза в сутки на протяжении 5-10 дней (продолжительность приема зависит от характера и тяжести патологического процесса). 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