Метродент Гель, 20 г, 10 мг + 0.5 мг / мл, лимон

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В низких концентрациях, нарушая осмотическое равновесие бактериальных клеток и выход из них ионов калия и фосфора, оказывает бактериостатическое действие; при высоких концентрациях цитоплазматическое содержимое бактериальной клетки осаждается, что ведет в конечном итоге к гибели бактерий."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Острый гингивит; острый некротический язвенный гингивит Винцента; хронический отечный гингивит; хронический гиперпластический гингивит; хронический атрофический (десквамативный) гингивит; хронический периодонтит; периодонтальный абсцесс; рецидивирующий афтозный (язвенный) стоматит; гангренозный пульпит; постэкстракционный альвеолит; юношеский пародонтит; зубная боль инфекционного происхождения."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Гиперчувствительность (в т.ч. к метронидазолу, хлоргексидину и производным нитроимидазола); детский возраст до 6 лет."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"беременность, период лактации."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Не рекомендуется применять препарат в I триместре беременности. При II и III триместре беременности применяют только в случае, если предполагаемая польза для матери превышает потенциальный риск для плода."}},{"type":"paragraph","data":{"text":"В период лактации, при необходимости назначения препарата, следует решить вопрос о прекращении грудного вскармливания."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Только для стоматологического применения."}},{"type":"paragraph","data":{"text":"Местно, после тщательной чистки зубов нанести на десны и межзубные промежутки. Применять 2 раза/сут."}},{"type":"paragraph","data":{"text":"С целью профилактики небольшое количество добавляется к зубной пасте."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eМестные реакции:\u003c/i\u003e \"металлический\" привкус во рту."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСистемные реакции\u003c/i\u003e: головная боль, аллергические реакции (кожная сыпь, зуд, крапивница)."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Усиливает антикоагулянтное действие \u003ci\u003eварфарина\u003c/i\u003e (увеличение времени образования протромбина)."}},{"type":"paragraph","data":{"text":"Одновременное применение с \u003ci\u003eдисульфирамом\u003c/i\u003e усиливает токсичность, что может привести к развитию неврологических симптомов."}},{"type":"paragraph","data":{"text":"Противомикробная активность метронидазола снижается при одновременном применении с\u003ci\u003e фенобарбиталом и фенитоином\u003c/i\u003e из-за ускоренного метаболизма метронидазола."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЦиметидин\u003c/i\u003e подавляет метаболизм метронидазола, что может привести к повышению концентрации метронидазола в сыворотке крови."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Применение лекарственного средства не заменяет гигиенической чистки зубов, поэтому во время курса лечения препаратом чистка зубов должна быть продолжена. Однако не следует сочетать наложение геля одновременно с зубной пастой."}},{"type":"paragraph","data":{"text":"Избегать попадания в глаза."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Гель стоматологический"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При температуре не выше 25 °C (не замораживать)"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2,5 года"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\u003ca href=\"https://www.vidal.ru/drugs/firm/6060\"\u003eMETIGRINS \u003c/a\u003e(Латвия)  "}}]}],"source":null},"description_toggle":false,"short_description":"Комбинированное противомикробное лекарственное средство для местного применения.Метронидазол- производное нитроимидазола, обладающего антипротозойным и антибактериальным действием против анаэробных простейших и анаэробных бактерий, вызывающих периодонтит: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp. Неактивен в отношении аэробных бактерий. Механизм действия заключается в биохимическом восстановлении 5-нитрогруппы метронидазола внутриклеточными транспортными протеинами анаэробных микроорганизмов и простейших. Восстановленная 5-нитрогруппа метронидазола взаимодействует с ДНК клетки микроорганизмов, ингибируя синтез их нуклеиновых кислот, что ведет к гибели бактерий.Хлоргексидин- дезинфицирующее средство, активен в отношении широкого спектра вегетативных форм грамотрицательных и грамположительных микроорганизмов, дрожжей, дерматофитов и липофильных вирусов. На споры бактерий действует только при повышенной температуре. Бактерицидный эффект обусловлен связыванием катионов (результат диссоциации соли хлоргексидина в физиологической среде) с отрицательно заряженными стенками бактериальных клеток и экстрамикробных комплексов. В низких концентрациях, нарушая осмотическое равновесие бактериальных клеток и выход из них ионов калия и фосфора, оказывает бактериостатическое действие; при высоких концентрациях цитоплазматическое содержимое бактериальной клетки осаждается, что ведет в конечном итоге к гибели бактерий.","substance":[],"branding":null,"valid_for_quick_buy":false,"is_available_to_delivery":true,"comments":null,"image_alt":"Метродент - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/225015/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/225015/share_default/"}},"diseases":[],"other_packages":[{"id":187990,"title":"Метродент","subtitle":{"full":"Гель, 20 г, 10 мг + 0.5 мг / мл, ананас","short":"Гель, 20 г, 10 мг + 0.5 мг / мл","package":"20 г, 10 мг + 0.5 мг / 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