Внешний вид - мягкие желатиновые капсулы, одинаковой конфигурации, без натеков и вмятин с равномерной по толщине оболочкой, герметичные, без повреждений и видимых воздушных и механических включений, цвет капсул от светло-желтого до желтого, по консистенции капсулы - упругие не хрупкие, свободно отделяющиеся друг от друга, капсулы содержат маслянистую жидкость от светло-желтого до желтого цвета, с характерным вкусом и незначительным запахом желатина. Специальные особенности: Не содержат ароматизаторов, консервантов и красителей. Гипоаллергенны, за исключением индивидуальной непереносимости компонентов продукта. При употреблении БАД в рекомендованных количествах (1 капсула в день) в организм будут поступать: масло оливковое рафинированное 297,7 мг желатин 96,3 мг глицерин 42,45 вода 11,25 масляный раствор витамина D3 (1млн МЕ/г) 2,0 мг, в том числе витамин D3 0,05 мг (50 мкг) смесь токоферолов 0,3 мг Пищевая ценность: на 1 капсулу массой 450 мг: жиры 300 мг; белок 84 мг, углеводы 0 мг. Энергетическая ценность 1 капсулы: 3,23 ккал/13,52 кДж Витамин D относится к группе жирорастворимых витаминов. Однако он не является собственно витамином в классическом смысле этого термина. Под термином «витамин D» понимают целую группу биологически активных веществ, куда входят инертный витамин D, получаемый из пищи (D2 - эргокальциферол) и синтезированный в коже (D3 - холекальциферол). Попадая в печень и почки, витамин D превращается в активный и очень важный метаболит - кальцитриол, обеспечивающий основные биологические эффекты витамина D. Оказывая многообразные биологические эффекты за счет взаимодействия со специфическими рецепторами в клетках многих тканей и органов, витамин D ведет себя как истинный гормон. Именно поэтому он получил второе название D-гормон. Основное количество витамина D образуется в коже под действием ультрафиолетовых лучей солнца. Образование витамина D идет особенно активно летом, в солнечную погоду. Содержание же витамина D в продуктах питания довольно низкое и не может покрыть потребностей организма в этом веществе. Наибольшее количество витамина D содержится в морской рыбе, рыбьем жире, яичных желтках, печени, коровьем молоке. Грудное молоко кормящих матерей, не получающих добавки, содержащие витамин D, имеет лишь небольшое количество витамина D, совершенно недостаточное для нормального развития новорожденного ребенка. Согласно оценкам ученых, дефицит витамина D широко распространен во всех возрастных группах. Этому способствует образ жизни человека в современных условиях. Очень немногие натуральные продукты содержат витамин D, лишь некоторые из пищевых продуктов дополнительно им обогащаются. Целый ряд факторов снижает производство кожного витамина D, в том числе повышенная пигментация кожи, её старение и применение солнцезащитных средств. Влияет и география: в широтах, расположенных выше широты 33°, синтез витамина D в коже очень низок или совсем отсутствует в течение большей части года. Нахождение в тени и облачная погода способны сократить синтез провитамина на 60%. Через стекло, одежду и крем от загара ультрафиолет, необходимый для синтеза провитамина, не проникает. Витамин D3 и его роль в организме Витамин D3 и костная ткань В первую очередь, витамин D3 участвует в регуляции обмена кальция и фосфора в организме. Он отвечает за всасывание этих микроэлементов из пищи в тонком кишечнике, а также активирует процесс встраивания кальция в костную ткань, активно способствует росту скелета, минерализации костей и зубов и укреплению мышц. Многочисленные исследования показали, что дополнительный прием витамина D3 повышает минеральную плотность кости и позвоночника, на 46% снижает частоту переломов шейки бедра и на 32% - всех других видов переломов. Витамин D3 и сердце Витамину D3 отводится важное значение в способности организма противодействовать болезням сердца. Существуют данные, свидетельствующие о том, что низкие уровни активного метаболита витамина D могут быть связаны с ускоренным развитием сердечно сосудистых заболеваний. Исследования показали обратную зависимость между уровнями витамина D и активностью ренина в плазме, артериальной гипертензией и кальцификацией коронарных артерий. По результатам многолетних наблюдений оказалось что люди, испытывавшие в детстве дефицит витамина D, в зрелом возрасте чаще страдали атеросклерозом, который провоцировал развитие ишемических заболеваний сердечно сосудистой системы. Низкие уровни витамина D были также связаны с фатальными инсультами, сердечной недостаточностью, внезапной кардиальной смертью и кальцинированным аортальным стенозом. Кардиологи уверены, что прием витамина D - простейшая профилактика сердечно-сосудистых проблем. Витамина D3 и онкология Витамин D3 активно противостоит онкологическим заболеваниям. Доказано, что у людей с достаточным уровнем витамина D3 в организме риск онкологических заболеваний, таких как рак молочной железы или рак кишечника, на 50% ниже, чем у людей дефицитом витамина D3. Исследования показали, что восполнение дефицита D3 при уже имеющемся онкологическом процессе оказывает положительное влияние на течение заболевания. Ученые утверждают, что шансы на выживаемость при высоком уровне витамина D у раковых больных значительно возрастают. Витамин D и сахарный диабет После открытия в бета-клетках поджелудочной железы витамин-D-рецепторов (VDR) началось активное изучение роли дефицита витамина D в развитии сахарного диабета 2 типа. Доказано, что дефицит витамина D снижает секрецию инсулина бета-клетками поджелудочной железы и увеличивает инсулинорезистентность - нечувствительность тканей к инсулину. Другие эффекты витамина D Отмечено также влияние кальциферола на мускулатуру (предупреждает слабость мышц) и иммунитет (повышает сопротивляемость организма инфекциям). Недаром при оценке предполагаемой продолжительности жизни больного СПИДом одним из важных показателей является уровень содержания в крови витамина D. Используют витамин D и при комплексном лечении рассеянного склероза. Здесь, благодаря свойству стимулировать усвоение магния и кальция, он восстанавливает защитную оболочку нерва, нормализует передачу нервных импульсов и процесс сокращения мышц. Таким образом, восполнение дефицита витамина D с помощью препаратов витамина D в настоящее время является практически необходимым условием достижения и поддержания нормальной концентрации кальцитриола в сыворотке крови. Согласно рекомендациям международных экспертов, для профилактики и лечения дефицита витамина D применяется холекальциферол, или витамин D3. Согласно Клиническим рекомендациям Российской ассоциации эндокринологов (2015) с целью профилактики дефицита витамина D у взрослых рекомендуется: -Лицам в возрасте 18-50 лет - получать не менее 600-800 МЕ витамина D в сутки. -Лицам старше 50 лет - не менее 800-1000 МЕ витамина D в сутки. -Беременным и кормящим женщинам - не менее 800-1200 МЕ витамина D в сутки. -Для поддержания уровня 25(ОН)D более 30 нг/мл может потребоваться потребление не менее 1500-2000 МЕ витамина D в сутки. -Пациенты с ожирением нуждаются в увеличении дозы витамина D в 2-3 раза - до 4000-6000 МЕ витамина D в сутки. -При заболеваниях/состояниях, сопровождающихся нарушением всасывания/метаболизма витамина D, рекомендуется прием витамина D в дозах в 2-3 раза превышающих суточную потребность возрастной группы. -Без медицинского наблюдения и контроля уровня 25(ОН)D в крови не рекомендуется назначение доз витамина D более 10 000 МЕ в сутки на длительный период (> 6 месяцев).
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Гипоаллергенны, за исключением индивидуальной непереносимости компонентов продукта.\u003cbr /\u003eПри употреблении БАД в рекомендованных количествах (1 капсула в день) в организм будут поступать:\u003cbr /\u003eмасло оливковое рафинированное 297,7 мг\u003cbr /\u003eжелатин 96,3 мг\u003cbr /\u003eглицерин 42,45\u003cbr /\u003eвода 11,25\u003cbr /\u003eмасляный раствор витамина D3 (1млн МЕ/г) 2,0 мг,\u003cbr /\u003eв том числе витамин D3 0,05 мг (50 мкг)\u003cbr /\u003eсмесь токоферолов 0,3 мг\u003cbr /\u003eПищевая ценность: на 1 капсулу массой 450 мг: жиры 300 мг; белок 84 мг, углеводы 0 мг.\u003cbr /\u003eЭнергетическая ценность 1 капсулы: 3,23 ккал/13,52 кДж\u003cbr /\u003eВитамин D относится к группе жирорастворимых витаминов. Однако он не является собственно витамином в классическом смысле этого термина.\u003cbr /\u003eПод термином «витамин D» понимают целую группу биологически активных веществ, куда входят инертный витамин D, получаемый из пищи (D2 - эргокальциферол) и синтезированный в коже (D3 - холекальциферол). Попадая в печень и почки, витамин D превращается в активный и очень важный метаболит - кальцитриол, обеспечивающий основные биологические эффекты витамина D. Оказывая многообразные биологические эффекты за счет взаимодействия со специфическими рецепторами в клетках многих тканей и органов, витамин D ведет себя как истинный гормон. Именно поэтому он получил второе название D-гормон.\u003cbr /\u003eОсновное количество витамина D образуется в коже под действием ультрафиолетовых лучей солнца. Образование витамина D идет особенно активно летом, в солнечную погоду. Содержание же витамина D в продуктах питания довольно низкое и не может покрыть потребностей организма в этом веществе. Наибольшее количество витамина D содержится в морской рыбе, рыбьем жире, яичных желтках, печени, коровьем молоке. Грудное молоко кормящих матерей, не получающих добавки, содержащие витамин D, имеет лишь небольшое количество витамина D, совершенно недостаточное для нормального развития новорожденного ребенка.\u003cbr /\u003eСогласно оценкам ученых, дефицит витамина D широко распространен во всех возрастных группах. Этому способствует образ жизни человека в современных условиях. Очень немногие натуральные продукты содержат витамин D, лишь некоторые из пищевых продуктов дополнительно им обогащаются. Целый ряд факторов снижает производство кожного витамина D, в том числе повышенная пигментация кожи, её старение и применение солнцезащитных средств. Влияет и география: в широтах, расположенных выше широты 33°, синтез витамина D в коже очень низок или совсем отсутствует в течение большей части года. Нахождение в тени и облачная погода способны сократить синтез провитамина на 60%. Через стекло, одежду и крем от загара ультрафиолет, необходимый для синтеза провитамина, не проникает.\u003cbr /\u003eВитамин D3 и его роль в организме\u003cbr /\u003eВитамин D3 и костная ткань\u003cbr /\u003eВ первую очередь, витамин D3 участвует в регуляции обмена кальция и фосфора в организме. Он отвечает за всасывание этих микроэлементов из пищи в тонком кишечнике, а также активирует процесс встраивания кальция в костную ткань, активно способствует росту скелета, минерализации костей и зубов и укреплению мышц.\u003cbr /\u003eМногочисленные исследования показали, что дополнительный прием витамина D3 повышает минеральную плотность кости и позвоночника, на 46% снижает частоту переломов шейки бедра и на 32% - всех других видов переломов.\u003cbr /\u003eВитамин D3 и сердце\u003cbr /\u003eВитамину D3 отводится важное значение в способности организма противодействовать болезням сердца. Существуют данные, свидетельствующие о том, что низкие уровни активного метаболита витамина D могут быть связаны с ускоренным развитием сердечно сосудистых заболеваний. Исследования показали обратную зависимость между уровнями витамина D и активностью ренина в плазме, артериальной гипертензией и кальцификацией коронарных артерий.\u003cbr /\u003eПо результатам многолетних наблюдений оказалось что люди, испытывавшие в детстве дефицит витамина D, в зрелом возрасте чаще страдали атеросклерозом, который провоцировал развитие ишемических заболеваний сердечно сосудистой системы.\u003cbr /\u003eНизкие уровни витамина D были также связаны с фатальными инсультами, сердечной недостаточностью, внезапной кардиальной смертью и кальцинированным аортальным стенозом. Кардиологи уверены, что прием витамина D - простейшая профилактика сердечно-сосудистых проблем.\u003cbr /\u003eВитамина D3 и онкология\u003cbr /\u003eВитамин D3 активно противостоит онкологическим заболеваниям. Доказано, что у людей с достаточным уровнем витамина D3 в организме риск онкологических заболеваний, таких как рак молочной железы или рак кишечника, на 50% ниже, чем у людей дефицитом витамина D3. Исследования показали, что восполнение дефицита D3 при уже имеющемся онкологическом процессе оказывает положительное влияние на течение заболевания. Ученые утверждают, что шансы на выживаемость при высоком уровне витамина D у раковых больных значительно возрастают.\u003cbr /\u003eВитамин D и сахарный диабет\u003cbr /\u003eПосле открытия в бета-клетках поджелудочной железы витамин-D-рецепторов (VDR) началось активное изучение роли дефицита витамина D в развитии сахарного диабета 2 типа. Доказано, что дефицит витамина D снижает секрецию инсулина бета-клетками поджелудочной железы и увеличивает инсулинорезистентность - нечувствительность тканей к инсулину.\u003cbr /\u003eДругие эффекты витамина D\u003cbr /\u003eОтмечено также влияние кальциферола на мускулатуру (предупреждает слабость мышц) и иммунитет (повышает сопротивляемость организма инфекциям). Недаром при оценке предполагаемой продолжительности жизни больного СПИДом одним из важных показателей является уровень содержания в крови витамина D.\u003cbr /\u003eИспользуют витамин D и при комплексном лечении рассеянного склероза. Здесь, благодаря свойству стимулировать усвоение магния и кальция, он восстанавливает защитную оболочку нерва, нормализует передачу нервных импульсов и процесс сокращения мышц.\u003cbr /\u003eТаким образом, восполнение дефицита витамина D с помощью препаратов витамина D в настоящее время является практически необходимым условием достижения и поддержания нормальной концентрации кальцитриола в сыворотке крови. Согласно рекомендациям международных экспертов, для профилактики и лечения дефицита витамина D применяется холекальциферол, или витамин D3.\u003cbr /\u003eСогласно Клиническим рекомендациям Российской ассоциации эндокринологов (2015) с целью профилактики дефицита витамина D у взрослых рекомендуется:\u003cbr /\u003e-Лицам в возрасте 18-50 лет - получать не менее 600-800 МЕ витамина D в сутки.\u003cbr /\u003e-Лицам старше 50 лет - не менее 800-1000 МЕ витамина D в сутки.\u003cbr /\u003e-Беременным и кормящим женщинам - не менее 800-1200 МЕ витамина D в сутки.\u003cbr /\u003e-Для поддержания уровня 25(ОН)D более 30 нг/мл может потребоваться потребление не менее 1500-2000 МЕ витамина D в сутки.\u003cbr /\u003e-Пациенты с ожирением нуждаются в увеличении дозы витамина D в 2-3 раза - до 4000-6000 МЕ витамина D в сутки.\u003cbr /\u003e-При заболеваниях/состояниях, сопровождающихся нарушением всасывания/метаболизма витамина D, рекомендуется прием витамина D в дозах в 2-3 раза превышающих 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