вспомогательные вещества: парафин белый мягкий — 150 мг; цетостеариловый спирт — 72 мг; парафин жидкий — 60 мг; макрогол-цетостеариловый эфир — 22,5 мг; фосфорная кислота и натрия гидроксид — q.s. (в виде 5% растворов в количестве, необходимом для установления рН); натрия дигидрофосфата дигидрат — 3,39 мг (эквивалентно 3 мг натрия дигидрофосфата моногидрата); хлоркрезол — 1 мг; вода очищенная — q.s. до 1 г.
Фармакотерапевтическая группа
глюкокортикостероид для местного применения.
Фармакологические свойства
Целестодерм-В - ГКС для наружного применения; оказывает противовоспалительное местное, противоаллергическое, противоотечное и антипролиферативное действие.
Бетаметазон оказывает противовоспалительное и противоаллергическое действие посредством торможения высвобождения цитокинов и медиаторов воспаления, уменьшения метаболизма арахидоновой кислоты, индуцирования образования липокортинов, обладающих противоотечной активностью, снижения проницаемости сосудов.
Микродисперсия этого глюкокортикостероида (ГКС) в нежирной, не имеющей запаха, не оставляющей следов на одежде, легко смывающейся мазевой или кремовой основе обеспечивает эффективное проникновение в кожу и быстрое начало действия.
- Беременность (при отсутствии критериев для противопоказания), особенно в 1-м триместре.
- Длительное лечение обширных участков кожи, особенно у детей.
- При наличии трещин кожи или использовании окклюзионных повязок.
Применение при беременности и в период грудного вскармливания
В связи с тем, что безопасность применения местных ГКС у беременных не была установлена, назначение препаратов этого класса во время беременности оправдано только, если польза для матери явно превышает возможный вред для плода. ГКС не должны применяться во время беременности длительно или в больших дозах.
Так как до настоящего времени не установлено, могут ли ГКС при местном применении и системной абсорбции проникать в грудное молоко, следует принять решение о прекращении кормления грудью или об отмене препарата, учитывая, насколько необходимо его применение для матери.
Способ применения и дозы
Наружно. Наносить тонким слоем на пораженные участки кожи 2 раза в день - утром и вечером.
Частоту применения, отличную от рекомендованной, может установить врач, ориентируясь на тяжесть заболевания.
В легких случаях применение один раз в день обычно является достаточным, при более тяжелых поражениях может потребоваться и более частое применение.
Побочное действие
При применении ГКС местного действия наблюдались следующие нежелательные явления: жжение, раздражение и сухость кожи, фолликулит, гипертрихоз, угревидные высыпания, гипопигментация, нейтральный дерматит, аллергический контактный дерматит, мацерация кожи, вторичная инфекция, атрофия кожи, стрии и потница.
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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