Фармакологическое действие Препарат компенсирует недостаточн... Инструкция
Показания к применению
Нарушение функции поджелудочной железы (недостаточность внешнесекреторной функции), например, хронические воспалительные заболевания поджелудочной железы (панкреатиты) или отсутствие желудочного сока (ахилия желудка).
Нарушение пищеварения в случае заболеваний печени и желчевыводящих путей.
Нарушение пищеварения после операций на желудке и тонком кишечнике, ...
Таблетки, покрытые оболочкой продолговатой формы белого или почти белого цвета.
Фармакотерапевтическая группа
пищеварительное ферментное средство.
Фармакологические свойства
Фармакологическое действие
Препарат компенсирует недостаточность внешнесекреторной функции поджелудочной железы
Панкреатин — порошок поджелудочной железы свиньи, содержащий ферменты: липазу, альфа-амилазу, трипсин, химотрипсин и др.
Липаза отщепляет жирные кислоты по позициям 1 и 3 молекул триглицеридов.
Свободные жирные кислоты, образующиеся при этом расщеплении, всасываются, главным образом, в верхнем отделе тонкого кишечника при участии желчных кислот.
Трипсин образуется из трипсиногена под действием энтерокиназы в тонком кишечнике и, как эндопептидаза, расщепляет, в основном, связи между пептидами при участии лизина и аргинина.
Согласно результатам последних клинических исследований, трипсин ингибирует по механизму отрицательной обратной связи секрецию поджелудочной железы.
Полагают, что болеутоляющий эффект панкреатина, описанный в некоторых исследованиях, связан с этим.
Альфа-амилаза, как и эндоамилаза, расщепляет полисахариды, содержащие глюкозу.
Диметикон, входящий в состав Панкреофлата, устраняет повышенное накопление газа в тонком кишечнике.
Фармакокинетика
Панкреатин и диметикон не всасываются из желудочно-кишечного тракта.
Показания к применению
Нарушение функции поджелудочной железы (недостаточность внешнесекреторной функции), например, хронические воспалительные заболевания поджелудочной железы (панкреатиты) или отсутствие желудочного сока (ахилия желудка).
Нарушение пищеварения в случае заболеваний печени и желчевыводящих путей.
Нарушение пищеварения после операций на желудке и тонком кишечнике, особенно, если эти заболевания связаны с повышенным газообразованием и скоплением газов в кишечнике (метеоризм).
Противопоказания
Повышенная чувствительность к панкреатину или другим компонентам препарата, детский возраст до 12 лет.
С осторожностью
препарат следует назначать на ранних стадиях острого панкреатита и при обострении хронического панкреатита, а также при непереносимости галактозы, лактазной недостаточности или нарушениями всасывания глюкозы-галактозы.
Применение при беременности и в период грудного вскармливания
Нет данных о токсическом действии на репродуктивную функцию и развитие плода.
Однако, так как исследования следует соблюдать осторожность при назначении препарата у беременных и кормящих женщин.
Способ применения и дозы
Препарат принимают внутрь, не разжевывая, запивая достаточным количеством жидкости, во время или после еды.
Взрослые — по 1–2 таблетки с каждым приемом пищи.
Для детей в возрасте от 12 лет режим дозирования подбирается индивидуально лечащим врачом.
Продолжительность курса лечения определяется врачом.
Побочное действие
Со стороны кожных покровов:
Возможны аллергические реакции в случае непереносимости какого-либо компонента препарата.
Со стороны пищеварительной системы:
Боли в животе, дискомфорт в области желудка, запор, диарея, тошнота, рвота, гиперурикозурия, повышение уровня мочевой кислоты в плазме крови.
Передозировка
Нет информации о возможных симптомах передозировки панкреатина/диметикона. При длительном применении препарата в высоких дозах возможны развитие гиперурикозурии, повышение уровня мочевой кислоты в плазме крови.
Взаимодействие с другими лекарственными средствами
Одновременное применение антацидных средств, содержащих алюминия гидроксид и/или магния карбонат, может привести к снижению эффективности диметикона.
Не было отмечено случаев клинически значимого взаимодействия панкреатина с другими лекарственными средствами.
Особые указания
Панкреофлат содержит активные ферменты, которые в случае высвобождения их в полости рта, могут приводить к изъязвлению слизистой оболочки. Препарат следует проглатывать целиком, не разжевывая, с достаточным количеством жидкости.
Влияние на способность управлять автомобилем и движущимися механизмами
Применение Панкреофлата не оказывает влияния на психомоторные функции, связанные с вождением автомобиля или управлением машинами и механизмами
Форма выпуска
Таблетки, покрытые оболочкой: по 25 таблеток в ПВХ/ПВДХ/Ал блистер. По 1 блистеру вместе с инструкцией по применению в картонную пачку.
Условия хранения
В сухом месте при температуре не выше 20 °С.
Хранить в недоступном для детей месте.
Срок годности
2 года.
Не применять по истечении срока годности.
Условия отпуска
Без рецепта.
Производитель
Солвей Фармасьютикалз ГмбХ, Ханса-Боклер-Аллее 20, 30173, Ганновер, Германия.
Адрес места производства: Юстуса-фон-Либиха-Штрассе 33, 31535 Нойштадт, Германия
Организация, принимающая претензии потребителей
Компания «Фармаселект Интернешнл Бетайлигунгс ГмбХ» Эрнст-Мелхиор-Штрассе 20 А-1020 Вена, Австрия
Для описания товара использована информация от партнера 36.6
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Ф."}},{"type":"paragraph","data":{"text":"Диметикон — 80 мг"}},{"type":"paragraph","data":{"text":"Вспомогательные вещества:"}},{"type":"paragraph","data":{"text":"кремния диоксид коллоидный — 4,0 мг; кислота сорбиновая — 0,56 мг; метилпарагидроксибензоат — 0,264 мг; пропилпарагидроксибензоат — 0,066 мг молоко сухое (порошок) — 180,07 мг; гипромеллоза — 15,0 мг; акации камедь — 30,00 мг; коповидон К 28 — 60,0 мг"}},{"type":"paragraph","data":{"text":"Оболочка:"}},{"type":"paragraph","data":{"text":"Акации камедь — 2,88 мг; коповидон К 28 — 3,30 мг; магния оксид (легкий) — 16,0 мг; кремния диоксид коллоидный — 0,17 мг; повидон К 28 — 5,35 мг; сахароза — 228,18 мг; шеллак — 1,22 мг; тальк — 54,87 мг; титана диоксид (Е171) — 14,43 мг; макрогол 6000 — 2,68 мг; натрия кармеллоза 2000 — 0,67 мг; капол 1295 (пчелиный воск — 2,0%; карнаубский воск 98 %) — 0,26 мг\n\n"}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Таблетки, покрытые 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образуется из трипсиногена под действием энтерокиназы в тонком кишечнике и, как эндопептидаза, расщепляет, в основном, связи между пептидами при участии лизина и аргинина."}},{"type":"paragraph","data":{"text":"Согласно результатам последних клинических исследований, трипсин ингибирует по механизму отрицательной обратной связи секрецию поджелудочной железы."}},{"type":"paragraph","data":{"text":"Полагают, что болеутоляющий эффект панкреатина, описанный в некоторых исследованиях, связан с этим."}},{"type":"paragraph","data":{"text":"Альфа-амилаза, как и эндоамилаза, расщепляет полисахариды, содержащие глюкозу."}},{"type":"paragraph","data":{"text":"Диметикон, входящий в состав Панкреофлата, устраняет повышенное накопление газа в тонком кишечнике."}},{"type":"paragraph","data":{"text":"Фармакокинетика"}},{"type":"paragraph","data":{"text":"Панкреатин и диметикон не всасываются из желудочно-кишечного тракта."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"\n\nНарушение функции поджелудочной железы (недостаточность внешнесекреторной функции), например, хронические воспалительные заболевания поджелудочной железы (панкреатиты) или отсутствие желудочного сока (ахилия желудка)."}},{"type":"paragraph","data":{"text":"Нарушение пищеварения в случае заболеваний печени и желчевыводящих путей."}},{"type":"paragraph","data":{"text":"Нарушение пищеварения после операций на желудке и тонком кишечнике, особенно, если эти заболевания связаны с повышенным газообразованием и скоплением газов в кишечнике (метеоризм).\n\n"}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к панкреатину или другим компонентам препарата, детский возраст до 12 лет."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"препарат следует назначать на ранних стадиях острого панкреатита и при обострении хронического панкреатита, а также при непереносимости галактозы, лактазной недостаточности или нарушениями всасывания глюкозы-галактозы."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"\n\nНет данных о токсическом действии на репродуктивную функцию и развитие плода."}},{"type":"paragraph","data":{"text":"Однако, так как исследования следует соблюдать осторожность при назначении препарата у беременных и кормящих женщин.\n\n"}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"\n\nПрепарат принимают внутрь, не разжевывая, запивая достаточным количеством жидкости, во время или после еды."}},{"type":"paragraph","data":{"text":"Взрослые — по 1–2 таблетки с каждым приемом пищи."}},{"type":"paragraph","data":{"text":"Для детей в возрасте от 12 лет режим дозирования подбирается индивидуально лечащим врачом."}},{"type":"paragraph","data":{"text":"Продолжительность курса лечения определяется врачом.\n\n"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"\n\nСо стороны кожных покровов:"}},{"type":"paragraph","data":{"text":"Возможны аллергические реакции в случае непереносимости какого-либо компонента препарата."}},{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы:"}},{"type":"paragraph","data":{"text":"Боли в животе, дискомфорт в области желудка, запор, диарея, тошнота, рвота, гиперурикозурия, повышение уровня мочевой кислоты в плазме крови.\n\n"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Нет информации о возможных симптомах передозировки панкреатина/диметикона. При длительном применении препарата в высоких дозах возможны развитие гиперурикозурии, повышение уровня мочевой кислоты в плазме крови."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\n\nОдновременное применение антацидных средств, содержащих алюминия гидроксид и/или магния карбонат, может привести к снижению эффективности диметикона."}},{"type":"paragraph","data":{"text":"Не было отмечено случаев клинически значимого взаимодействия панкреатина с другими лекарственными средствами.\n\n"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":" Панкреофлат содержит активные ферменты, которые в случае высвобождения их в полости рта, могут приводить к изъязвлению слизистой оболочки. Препарат следует проглатывать целиком, не разжевывая, с достаточным количеством жидкости. "}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Применение Панкреофлата не оказывает влияния на психомоторные функции, связанные с вождением автомобиля или управлением машинами и механизмами"}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Таблетки, покрытые оболочкой: по 25 таблеток в ПВХ/ПВДХ/Ал блистер. По 1 блистеру вместе с инструкцией по применению в картонную пачку."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"\n\nВ сухом месте при температуре не выше 20 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте.\n\n"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"\n\n2 года."}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности.\n\n"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nСолвей Фармасьютикалз ГмбХ, Ханса-Боклер-Аллее 20, 30173, Ганновер, Германия."}},{"type":"paragraph","data":{"text":"Адрес места производства: Юстуса-фон-Либиха-Штрассе 33, 31535 Нойштадт, Германия\n\n"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"Компания «Фармаселект Интернешнл Бетайлигунгс ГмбХ» Эрнст-Мелхиор-Штрассе 20 А-1020 Вена, Австрия"}}]}],"source":null},"description_toggle":false,"short_description":"Фармакологическое действие Препарат компенсирует недостаточность внешнесекреторной функции поджелудочной железы Панкреатин — порошок поджелудочной железы свиньи, содержащий ферменты: липазу, альфа-амилазу, трипсин, химотрипсин и др. 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