Лоперамид Капсулы, 10 шт, 2 мг

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Симптоматическое лечение: активированный уголь, промывание желудка, искусственная вентиляция легких."}},{"type":"paragraph","data":{"text":"Необходимо медицинское наблюдение, по крайней мере, в течение 48 часов."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Не отмечалось."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"При отсутствии эффекта после 2-х суток применения Лоперамида необходимо обратиться к врачу."}},{"type":"paragraph","data":{"text":"Если при лечении развиваются запоры или вздутие живота, лоперамид следует отменить."}},{"type":"paragraph","data":{"text":"У пациентов с нарушением функции печени необходим тщательный контроль за признаками токсического поражения ЦНС."}},{"type":"paragraph","data":{"text":"В период лечения диареи необходимо восполнять потерю жидкости и электролитов."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"В период лечения необходимо соблюдать осторожность при управлении транспортными средствами и занятии др. потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы 2 мг."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в сухом, защищенном от света, недоступном для детей месте, при температуре не выше 25 °С."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Не применять по истечении срока годности указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ООО \"Производство Медикаментов\", 346720, Ростовская обл., Аксайский район, г. Аксай, ул. Ленина, д. 43, Россия"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"ООО \"Производство Медикаментов\""}}]}],"source":null},"description_toggle":false,"short_description":"Лоперамид, связываясь с опиоидными рецепторами кишечной стенки (стимуляция холин- и адренергических нейронов через гуанин-нуклеотиды), снижает тонус и моторику гладкой мускулатуры кишечника, замедляет пассаж содержимого кишечника, уменьшает выделение жидкости и электролитов с фекалиями. Повышает тонус анального сфинктера, способствует удержанию каловых масс и урежению позывов к дефекации. Действие наступает быстро и продолжается 4-6 часов. Абсорбция - 40 %. Время, необходимое для достижения максимальной концентрации (ТСcmах) - 2,5 часа. Связь с белками плазмы - 97 %. Период полувыведения - 9-14 ч. Не проникает через гематоэнцефалический барьер. Практически полностью метаболизируется в печени путем конъюгации. Выводится преимущественно кишечником; незначительная часть выводится почками (в виде конъюгированных метаболитов).","substance":[{"id":613,"title":"Лоперамид","title_latin":"Loperamidum","slug":"loperamid_613"}],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":true,"comments":null,"image_alt":"Лоперамид - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/196638/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/196638/share_default/"}},"diseases":[],"other_packages":[{"id":142199,"title":"Лоперамид","subtitle":{"full":"Капсулы, 10 шт, 2 мг","short":"Капсулы, 10 шт, 2 мг","package":"10 шт, 2 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