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ИБС, стенокардия)"}},{"type":"paragraph","data":{"text":"-     \nГиперплазия предстательной железы"}},{"type":"paragraph","data":{"text":"-     \nПовышенная чувствительность к\nадренергическим препаратам, сопровождающаяся бессонницей, головокружением,\nаритмией, тремором, повышением артериального давления"}},{"type":"paragraph","data":{"text":"-     \nПациенты с синдромом удлиненного\nинтервала QT"}}]},{"id":10,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"Препарат не следует применять в период\nбеременности. В период грудного вскармливания препарат применяется только после\nтщательной оценки соотношения риска и пользы для матери и младенца, под\nконтролем врача. Не допускается превышать рекомендуемую дозировку."}}]},{"id":11,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Интраназально. Перед\nприменением необходимо очистить носовые ходы."}},{"type":"paragraph","data":{"text":"Взрослым и детям старше 12 лет: применяют\n0,1 % раствор ксилометазолина по "}},{"type":"paragraph","data":{"text":"\n1 впрыскиванию в каждый носовой ход 3 раза в сутки. "}},{"type":"paragraph","data":{"text":"Детям от 6 до 11 лет: применяют 0,05\n% раствор ксилометазолина по 1-2 впрыскивания в каждый носовой ход 2-3 раза в\nсутки."}},{"type":"paragraph","data":{"text":"Детям от 2 до 5 лет: применяют 0,05 %\nраствор ксилометазолина по 1 впрыскиванию в каждый носовой ход 1-3 раза в\nсутки. "}},{"type":"paragraph","data":{"text":"Препарат у детей следует применять\nпод наблюдением взрослых. Не следует применять более 3 раз в сутки.\nРекомендуется последнюю аппликацию проводить непосредственно перед сном.\u003cb\u003e\u003c/b\u003e"}}]},{"id":12,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Классификация частоты возникновения\nпобочных реакций:"}},{"type":"paragraph","data":{"text":"очень часто (≥ 10); часто (≥ 1/100,\n< 1/10); нечасто (≥ 1/1000, < 1/100); редко (≥ 1/10000, < 1/1000); очень редко (< 1/10000)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны иммунной системы: \u003c/i\u003eочень редко – реакции гиперчувствительности (ангионевротический\nотек, сыпь, зуд)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны нервной системы:\u003c/i\u003e часто\u003ci\u003e \u003c/i\u003e-\nголовная боль. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения психики:\u003c/i\u003e редко - бессонница, депрессия (при длительном применении в\nвысоких дозах)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны органов чувств:\u003c/i\u003e очень редко - нарушение четкости зрительного\nвосприятия. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны сердечно-сосудистой системы: \u003c/i\u003eредко - ощущение сердцебиения, повышение\nартериального давления; очень редко - тахикардия, аритмия."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны дыхательной системы, органов грудной клетки и\nсредостения: \u003c/i\u003eчасто -\nраздражение и/или сухость слизистой оболочки носа, жжение, покалывание,\nчихание, гиперсекреция слизистой оболочки носоглотки, медикаментозный ринит. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения со стороны желудочно-кишечного тракта: \u003c/i\u003eчасто \u003ci\u003e–\u003c/i\u003e тошнота; редко - рвота. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eОбщие расстройства и нарушения в месте введения:\u003c/i\u003e часто - жжение в месте применения. "}},{"type":"paragraph","data":{"text":"Если любые из указанных в инструкции\nпобочных эффектов усугубляются, или Вы"}},{"type":"paragraph","data":{"text":"\nзаметили любые другие побочные эффекты, не указанные в инструкции, сообщите об\nэтом врачу."}}]},{"id":13,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"Ксилометазолин при местном\nвведении чрезмерной дозы или при случайном приеме внутрь может вызывать сильное\nголовокружение, повышенное потоотделение, резкое снижение температуры тела,\nголовную боль, брадикардию, повышение артериального давления, угнетение\nдыхания, кому и судороги. Вслед за повышением артериального давления может\nнаблюдаться его резкое снижение. Соответствующие поддерживающие меры должны\nприниматься при любых подозрениях на передозировку, в некоторых случаях показано\nнезамедлительное симптоматическое лечение под наблюдением врача. Эти меры\nдолжны включать наблюдение за пациентом в течение нескольких часов. В\u003cb\u003e \u003c/b\u003eслучае тяжелого отравления с\nостановкой сердца реанимационные действия должны продолжаться не менее 1 часа."}}]},{"id":14,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Ксилометазолин противопоказан\nпациентам, получающим ингибиторы МАО в данное время или получавшим их в течение\n2 предыдущих недель."}},{"type":"paragraph","data":{"text":"Одновременное применение\nтри- или тетрациклических антидепрессантов и симпатомиметических препаратов\nмогут привести к увеличению симпатомиметического эффекта ксилометазолина,\nпоэтому такое сочетание противопоказано."}}]},{"id":15,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"Не рекомендуется применять в\nнепрерывном режиме более 10 дней."}},{"type":"paragraph","data":{"text":"Не следует превышать\nрекомендованные дозы, особенно у детей и пожилых людей. Длительное (более 10\nдней) или чрезмерное применение препарата может вызвать эффект «рикошета» (медикаментозный\nринит) и/или атрофию слизистой оболочки полости носа. Бензалкония хлорид,\nвходящий в состав препарата, может вызвать раздражение слизистой оболочки\nполости носа."}},{"type":"paragraph","data":{"text":"Пациенты с синдромом\nудлиненного интервала QT, получающие ксилометазолин, могут подвергаться повышенному\nриску развития серьезных желудочковых аритмий."}}]},{"id":16,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Ксилометазолин\nне влияет на способность управлять транспортными средствами, механизмами."}}]},{"id":18,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"При\nтемпературе не выше 25 \u003csup\u003eо\u003c/sup\u003eС. Хранить в недоступном для детей месте."}}]},{"id":19,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3\nгода."}},{"type":"paragraph","data":{"text":"Не\nприменять по истечении срока годности."}}]},{"id":20,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают\nбез рецепта."}}]},{"id":21,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ООО «ВЕРОФАРМ»"}},{"type":"paragraph","data":{"text":"\u003ci\u003eАдрес производства и принятия претензий: \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Россия, 601125, Владимирская обл.,\nПетушинский район, пос. Вольгинский, ул. Заводская, владение 120."}},{"type":"paragraph","data":{"text":"Тел.: (49243) 7-17-53 "}},{"type":"paragraph","data":{"text":"или"}},{"type":"paragraph","data":{"text":"Россия, 308013, г. Белгород, ул.\nРабочая, д.14."}},{"type":"paragraph","data":{"text":"Тел.: (4722) 21-32-26; факс: (4722)\n21-34-71."}}]}],"source":null},"description_toggle":false,"short_description":"ФармакодинамикаКсилометазолин относится к группе местных сосудосуживающих средств (деконгестантов) с α-адреномиметическим действием, вызывает сужение кровеносных сосудов слизистой оболочки носа, устраняя отек и гиперемию слизистой оболочки носоглотки. Ксилометазолин также уменьшает сопутствующую гиперсекрецию слизи и облегчает дренаж заблокированных выделениями носовых ходов, и, таким образом, улучшает носовое дыхание при заложенности носа. Ксилометазолин хорошо переносится пациентами с чувствительной слизистой оболочкой, его воздействие не препятствует отделению слизи. Ксилометазолин имеет сбалансированное значение pH, характерное для полости носа. В терапевтических концентрациях препарат не раздражает слизистую оболочку, не вызывает гиперемию. Действие наступает через 2 минуты после применения и продолжается в течение 12 часов (например, в течение всей ночи). 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