Твердые желатиновые капсулы № 2 (для дозировки 100 мг) и № 0 (для дозировки 200 мг) желтого цвета. Содержимое капсул - смесь гранул и порошка желтого цвета. Допускается наличие спрессованной массы желтого цвета, распадающейся при нажатии.
Блокирует активность дегидрогеназ и угнетает дыхательные цепи, цикл трикарбоновых кислот и ряд других биохимических процессов в микробной клетке. Разрушает мембрану микробной клетки, снижает продукцию токсинов микроорганизмами.
Высокоактивен в отношении Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp.; Clostridium perfringens, Vibrio cholerae, патогенных Vibrions и Vibrio parahaemolytique, Staphylococcus spp.
Слабо чувствительны к нифуроксазиду: Citrobacter spp., Enterobacter cloacae и Proteus indologenes. Резистентны к нифуроксазиду: Klebsiella spp., Proteus mirabilis, Providencia spp., Pseudomonas spp.
Нифуроксазид не нарушает равновесие кишечной микрофлоры. При острой бактериальной диарее восстанавливает эубиоз кишечника. При инфицировании энтеротропными вирусами препятствует развитию бактериальной суперинфекции.
Фармакокинетика:
После перорального применения нифуроксазид практически не всасывается из пищеварительного тракта и оказывает свое антибактериальное действие исключительно в просвете кишечника. Нифуроксазид выводится кишечником: 20% в неизмененном виде, а остальное количество нифуроксазида - химически измененным.
Показания к применению
Острая бактериальная диарея, протекающая без ухудшения общего состояния, повышения температуры тела, интоксикации.
Противопоказания
- Повышенная чувствительность к нифуроксазиду, производным нитрофурана или другим компонентам препарата;
- беременность;
- детский возраст до 3 лет (для данной лекарственной формы);
заболевания печени, алкоголизм, черепно-мозговая травма, заболевания головного мозга; период грудного вскармливания; детский возраст.
Применение при беременности и в период грудного вскармливания
Беременность
В исследованиях на животных не было выявлено тератогенного эффекта. Однако в качестве меры предосторожности принимать препарат Нифуроксазид-ВЕРТЕКС во время беременности противопоказано.
Период грудного вскармливания
Во время периода лактации возможно продолжение грудного вскармливания в случае короткого курса лечения препаратом. Необходимо проконсультироваться с врачом.
Способ применения и дозы
Внутрь.
Капсулу следует проглатывать целиком, запивая небольшим количеством воды.
Капсулы 100 мг
Детям от 3 до 6 лет
По 2 капсулы (200 мг) 3 раза в сутки (интервал между приемами 8 часов).
Детям от 6 до 18 лет
По 2 капсулы (200 мг) 3-4 раза в сутки (интервал между приемами 6-8 часов).
Взрослым
По 2 капсулы (200 мг) 4 раза в сутки (интервал между приемами 6 часов).
Капсулы 200 мг
Детям от 3 до 6 лет
По 1 капсуле (200 мг) 3 раза в сутки (интервал между приемами 8 часов).
Детям от 6 до 18 лет
По 1 капсуле (200 мг) 3-4 раза в сутки (интервал между приемами 6-8 часов).
Взрослым
По 1 капсуле (200 мг) 4 раза в сутки (интервал между приемами 6 часов). Продолжительность курса лечения составляет 5-7 дней, но не более 7 дней. Если в течение первых трех дней приема улучшения не наступило, то следует обратиться к врачу.
Применяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции. В случае необходимости, пожалуйста, проконсультируйтесь с врачом перед применением препарата Нифуроксазид-ВЕРТЕКС.
Побочное действие
Аллергические реакции (кожная сыпь, крапивница, отек Квинке, анафилактический шок).
Если любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.
Передозировка
Симптомы
Симптомы передозировки не известны.
Лечение
Симптоматическое.
Взаимодействие с другими лекарственными средствами
Не рекомендуется одновременное применение с препаратами, вызывающими развитие дисульфирамоподобных реакций (боль в животе, тошнота, рвота, головная боль, тахикардия, нечеткое зрение, слабость, судороги), лекарственными препаратами, угнетающими функцию центральной нервной системы.
Если Вы принимаете другие лекарственные препараты (в том числе безрецептурные), перед применением препарата Нифуроксазид - ВЕРТЕКС проконсультируйтесь с врачом.
Особые указания
При лечении диареи одновременно с терапией нифуроксазидом необходимо проводить регидратационную терапию (пероральную или внутривенную) в соответствии с состоянием пациента и интенсивностью диареи.
В случае бактериальной диареи с признаками системного поражения (ухудшение общего состояния, повышение температуры тела, симптомы интоксикации при инфекции) следует обратиться к врачу для решения вопроса о применении антибактериальных препаратов системного действия.
При появлении симптомов гиперчувствительности (одышка, сыпь, зуд) следует прекратить прием препарата.
Употребление алкоголя во время терапии запрещено.
Указание для пациентов с сахарным диабетом
Одна разовая доза (2 капсулы 100 мг или 1 капсула 200 мг) препарата Нифуроксазид-ВЕРТЕКС содержит 72,0 мг сахарозы, что соответствует 0,006 Хлебной Единицы (ХЕ).
Максимальная суточная доза (8 капсул 100 мг или 4 капсулы 200 мг) содержит 288 мг сахарозы, что соответствует 0,024 ХЕ (1 ХЕ = 12 граммов углеводов).
Влияние на способность управлять автомобилем и движущимися механизмами
Препарат не оказывает влияния на способность к управлению транспортными средствами и механизмами.
Форма выпуска
Капсулы, 100 мг и 200 мг.
Условия хранения
Хранить в защищенном от света месте, при температуре не выше 25 °С.
Хранить в недоступном для детей месте.
Срок годности
2 года.
Не применять по истечении срока годности.
Условия отпуска
Без рецепта
Производитель
Акционерное общество "ВЕРТЕКС" (АО "ВЕРТЕКС"), г. Санкт-Петербург, Дорога в Каменку, д.62, лит. А, Россия
Организация, принимающая претензии потребителей
АО "ВЕРТЕКС"
Для описания товара использована информация от партнера 36.6
Мобильное приложение «Все аптеки»
Начните сравнивать цены и заказывать лекарства прямо в приложении
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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номер","slug":"","body":[{"type":"paragraph","data":{"text":"ЛП-004463"}}]},{"id":2,"name":"Торговое название препарата","slug":"","body":[{"type":"paragraph","data":{"text":"Нифуроксазид-ВЕРТЕКС"}}]},{"id":3,"name":"Лекарственная форма","slug":"","body":[{"type":"paragraph","data":{"text":"капсулы"}}]},{"id":4,"name":"Состав","slug":"ingredients","body":[{"type":"paragraph","data":{"text":"1 капсула содержит:"}},{"type":"paragraph","data":{"text":"\u003ci\u003eДозировка 100 мг\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eдействующее вещество:\u003c/i\u003e нифуроксазид - 100,0 мг;"}},{"type":"paragraph","data":{"text":"\u003ci\u003eвспомогательные вещества:\u003c/i\u003e крахмал кукурузный - 44,0 мг; сахароза - 36,0 мг; магния стеарат - 0,9 мг;"}},{"type":"paragraph","data":{"text":"\u003ci\u003eкапсулы твердые желатиновые: \u003c/i\u003eтитана диоксид - 2,0%; железа оксид желтый (железа оксид) - 0,6286%; желатин - до 100%."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДозировка 200 мг\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eдействующее вещество:\u003c/i\u003e нифуроксазид - 200,0 мг;"}},{"type":"paragraph","data":{"text":"\u003ci\u003eвспомогательные вещества:\u003c/i\u003e крахмал кукурузный - 88,0 мг; сахароза - 72,0 мг; магния стеарат -1,8 мг;"}},{"type":"paragraph","data":{"text":"\u003ci\u003eкапсулы твердые желатиновые:\u003c/i\u003e титана диоксид - 2,0%; железа оксид желтый (железа оксид) - 0,6286%; желатин - до 100%."}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Твердые желатиновые капсулы № 2 (для дозировки 100 мг) и № 0 (для дозировки 200 мг) желтого цвета. Содержимое капсул - смесь гранул и порошка желтого цвета. Допускается наличие спрессованной массы желтого цвета, распадающейся при нажатии."}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"Противомикробное средство - нитрофуран"}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"header","data":{"text":"Фармакодинамика:","level":3}},{"type":"paragraph","data":{"text":"Нифуроксазид - противомикробное средство, производное нитрофурана."}},{"type":"paragraph","data":{"text":"Блокирует активность дегидрогеназ и угнетает дыхательные цепи, цикл трикарбоновых кислот и ряд других биохимических процессов в микробной клетке. Разрушает мембрану микробной клетки, снижает продукцию токсинов микроорганизмами."}},{"type":"paragraph","data":{"text":"Высокоактивен в отношении \u003ci\u003eCampylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp.; Clostridium perfringens, Vibrio cholerae, патогенных Vibrions и Vibrio parahaemolytique, Staphylococcus spp.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Слабо чувствительны к нифуроксазиду: \u003ci\u003eCitrobacter spp., Enterobacter cloacae и Proteus indologenes. Резистентны к нифуроксазиду: Klebsiella spp., Proteus mirabilis, Providencia spp., Pseudomonas spp.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Нифуроксазид не нарушает равновесие кишечной микрофлоры. При острой бактериальной диарее восстанавливает эубиоз кишечника. При инфицировании энтеротропными вирусами препятствует развитию бактериальной суперинфекции."}},{"type":"header","data":{"text":"Фармакокинетика:","level":3}},{"type":"paragraph","data":{"text":"После перорального применения нифуроксазид практически не всасывается из пищеварительного тракта и оказывает свое антибактериальное действие исключительно в просвете кишечника. Нифуроксазид выводится кишечником: 20% в неизмененном виде, а остальное количество нифуроксазида - химически измененным."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Острая бактериальная диарея, протекающая без ухудшения общего состояния, повышения температуры тела, интоксикации."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"- Повышенная чувствительность к нифуроксазиду, производным нитрофурана или другим компонентам препарата;"}},{"type":"paragraph","data":{"text":"- беременность;"}},{"type":"paragraph","data":{"text":"- детский возраст до 3 лет (для данной лекарственной формы);"}},{"type":"paragraph","data":{"text":"- дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"заболевания печени, алкоголизм, черепно-мозговая травма, заболевания головного мозга; период грудного вскармливания; детский возраст."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eБеременность\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"В исследованиях на животных не было выявлено тератогенного эффекта. Однако в качестве меры предосторожности принимать препарат Нифуроксазид-ВЕРТЕКС во время беременности противопоказано."}},{"type":"paragraph","data":{"text":"\u003ci\u003eПериод грудного вскармливания\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Во время периода лактации возможно продолжение грудного вскармливания в случае короткого курса лечения препаратом. Необходимо проконсультироваться с врачом."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь."}},{"type":"paragraph","data":{"text":"Капсулу следует проглатывать целиком, запивая небольшим количеством воды."}},{"type":"paragraph","data":{"text":"\u003ci\u003eКапсулы 100 мг\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 3 до 6 лет\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 2 капсулы (200 мг) 3 раза в сутки (интервал между приемами 8 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 6 до 18 лет\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 2 капсулы (200 мг) 3-4 раза в сутки (интервал между приемами 6-8 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВзрослым\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 2 капсулы (200 мг) 4 раза в сутки (интервал между приемами 6 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eКапсулы 200 мг\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 3 до 6 лет\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 1 капсуле (200 мг) 3 раза в сутки (интервал между приемами 8 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eДетям от 6 до 18 лет\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 1 капсуле (200 мг) 3-4 раза в сутки (интервал между приемами 6-8 часов)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВзрослым\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"По 1 капсуле (200 мг) 4 раза в сутки (интервал между приемами 6 часов). Продолжительность курса лечения составляет 5-7 дней, но не более 7 дней. Если в течение первых трех дней приема улучшения не наступило, то следует обратиться к врачу."}},{"type":"paragraph","data":{"text":"Применяйте препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции. В случае необходимости, пожалуйста, проконсультируйтесь с врачом перед применением препарата Нифуроксазид-ВЕРТЕКС."}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Аллергические реакции (кожная сыпь, крапивница, отек Квинке, анафилактический шок)."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.\u003c/i\u003e"}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Симптомы передозировки не известны."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Симптоматическое."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"Не рекомендуется одновременное применение с препаратами, вызывающими развитие дисульфирамоподобных реакций (боль в животе, тошнота, рвота, головная боль, тахикардия, нечеткое зрение, слабость, судороги), лекарственными препаратами, угнетающими функцию центральной нервной системы."}},{"type":"paragraph","data":{"text":"Если Вы принимаете другие лекарственные препараты (в том числе безрецептурные), перед применением препарата Нифуроксазид - ВЕРТЕКС проконсультируйтесь с врачом."}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"При лечении диареи одновременно с терапией нифуроксазидом необходимо проводить регидратационную терапию (пероральную или внутривенную) в соответствии с состоянием пациента и интенсивностью диареи."}},{"type":"paragraph","data":{"text":"В случае бактериальной диареи с признаками системного поражения (ухудшение общего состояния, повышение температуры тела, симптомы интоксикации при инфекции) следует обратиться к врачу для решения вопроса о применении антибактериальных препаратов системного действия."}},{"type":"paragraph","data":{"text":"При появлении симптомов гиперчувствительности (одышка, сыпь, зуд) следует прекратить прием препарата."}},{"type":"paragraph","data":{"text":"Употребление алкоголя во время терапии запрещено."}},{"type":"paragraph","data":{"text":"\u003ci\u003eУказание для пациентов с сахарным диабетом\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Одна разовая доза (2 капсулы 100 мг или 1 капсула 200 мг) препарата Нифуроксазид-ВЕРТЕКС содержит 72,0 мг сахарозы, что соответствует 0,006 Хлебной Единицы (ХЕ)."}},{"type":"paragraph","data":{"text":"Максимальная суточная доза (8 капсул 100 мг или 4 капсулы 200 мг) содержит 288 мг сахарозы, что соответствует 0,024 ХЕ (1 ХЕ = 12 граммов углеводов)."}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Препарат не оказывает влияния на способность к управлению транспортными средствами и механизмами."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"Капсулы, 100 мг и 200 мг."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в защищенном от света месте, при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года."}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"Акционерное общество \"ВЕРТЕКС\" (АО \"ВЕРТЕКС\"), г. Санкт-Петербург, Дорога в Каменку, д.62, лит. А, Россия"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"АО \"ВЕРТЕКС\""}}]}],"source":null},"description_toggle":false,"short_description":"Нифуроксазид - противомикробное средство, производное нитрофурана. Блокирует активность дегидрогеназ и угнетает дыхательные цепи, цикл трикарбоновых кислот и ряд других биохимических процессов в микробной клетке. Разрушает мембрану микробной клетки, снижает продукцию токсинов микроорганизмами. Высокоактивен в отношенииCampylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp.; Clostridium perfringens, Vibrio cholerae, патогенных Vibrions и Vibrio parahaemolytique, Staphylococcus spp.Слабо чувствительны к нифуроксазиду:Citrobacter spp., Enterobacter cloacae и Proteus indologenes. 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