Аскорутин Таблетки, 50 шт, 50 + 50 мг + мг, для приема внутрь, для взрослых

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В составе комплексной терапии при варикозном расширении вен, трофических нарушениях и язвах кожи, при хронической венозной недостаточности; при геморрагическом диатезе."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"list","data":{"style":"ordered","items":["Повышенная индивидуальная чувствительность к компонентам препарата;","врожденная непереносимость фруктозы, глюкозо-галактозная мальабсорбция, дефицит сахаразы/изомальтазы;","беременность (1 триместр);","детский возраст до 18 лет."]}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"\n\nСостояния, сопровождающиеся гиперкоагуляцией крови и склонностью к тромбозам, тромбофлебит, сахарный диабет."}},{"type":"paragraph","data":{"text":"Если у Вас одно из перечисленных заболеваний, перед приемом препарата обязательно проконсультируйтесь с врачом.\n\n"}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"\n\nИз-за содержания в препарате рутина его не следует применять в 1 триместре беременности."}},{"type":"paragraph","data":{"text":"При применении препарата во время беременности (II-III триместры) и в период грудного вскармливания необходимо соблюдать дозировку и длительность курса приема, назначенные врачом.\n\n"}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"\n\nВнутрь."}},{"type":"paragraph","data":{"text":"По 1 таблетке 2-3 раза в сутки во время или после приема пищи. Курс лечения - 2-3 недели."}},{"type":"paragraph","data":{"text":"Если после лечения улучшения не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом."}},{"type":"paragraph","data":{"text":"Применяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции.\n\n"}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Возможны аллергические реакции (кожная сыпь), диспепсические расстройства, головная боль."}},{"type":"paragraph","data":{"text":"Важно сообщать о развитии нежелательных реакций с целью обеспечения непрерывного мониторинга отношения пользы и риска лекарственного препарата. Если любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу. Медицинские работники сообщают о нежелательных реакциях лекарственного препарата через национальные системы сообщения о нежелательных реакциях."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"\n\nСимптомы: чрезмерное употребление препарата может вызвать тошноту, рвоту, понос, головную боль."}},{"type":"paragraph","data":{"text":"Лечение: симптоматическое, форсированный диурез."}},{"type":"paragraph","data":{"text":"При передозировке лекарственным препаратом необходимо немедленно обратиться к врачу.\n\n"}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\n\nАскорбиновая кислота повышает всасывание лекарственных средств группы пенициллина, железа; снижает клинический эффект гепарина и непрямых антикоагулянтов, что требует коррекции доз при их одновременном применении."}},{"type":"paragraph","data":{"text":"Если вы применяете вышеперечисленные или другие лекарственные препараты (в том числе безрецептурные) перед применением лекарственного препарата Аскорутин проконсультируйтесь с врачом.\n\n"}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nПациентам с сахарным диабетом необходимо учитывать, что в одной таблетке препарата содержится около 0,2 г углеводов (0,017 ХЕ)."}},{"type":"paragraph","data":{"text":"При самостоятельном применении препарата рекомендуется не превышать максимальные сроки и рекомендуемые дозы."}},{"type":"paragraph","data":{"text":"В случае отсутствия уменьшения или при утяжелении симптомов заболевания рекомендуется обратиться к врачу.\n\n"}}]},{"id":17,"name":"Влияние на способность управлять автомобилем и движущимися механизмами","slug":"","body":[{"type":"paragraph","data":{"text":"Применение препарата не влияет на способность к выполнению потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (управление транспортом, работа с движущимися механизмами)."}}]},{"id":18,"name":"Форма выпуска","slug":"","body":[{"type":"paragraph","data":{"text":"\n\nТаблетки, 50 мг + 50 мг."}},{"type":"paragraph","data":{"text":"По 10 таблеток в контурную ячейковую упаковку из пленки поливинилхлоридной и фольги алюминиевой печатной лакированной."}},{"type":"paragraph","data":{"text":"5 контурных ячейковых упаковок по 10 таблеток с инструкцией по применению помещают в пачку из картона для потребительской тары.\n\n"}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"\n\nПри температуре не выше 25 °С в пачке."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте.\n\n"}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"\n\n3 года."}},{"type":"paragraph","data":{"text":"Не применять по истечении срока годности.\n\n"}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Отпускают без рецепта."}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"АО «Производственная фармацевтическая компания Обновление»"}}]},{"id":23,"name":"Организация, принимающая претензии потребителей","body":[{"type":"paragraph","data":{"text":"АО «Производственная фармацевтическая компания Обновление»"}}]}],"source":null},"description_toggle":false,"short_description":"Фармакодинамика Аскорбиновая кислота участвует в регуляции окислительно-восстановительных процессов, углеводного обмена, свертываемости крови, регенерации тканей, способствует повышению сопротивляемости организма. Рутозид (производное рутина) устраняет повышенную проницаемость капилляров, укрепляет сосудистую стенку, уменьшая ее отечность и воспаление. Обладает ангиагрегантным действием, что способствует улучшению микроциркуляции. Фармакокинетика Аскорбиновая кислота Всасывание Абсорбируется в желудочно-кишечном тракте (ЖКТ), преимущественно в тощей кишке. С увеличением дозы до 200 мг всасывается до 140 мг (70 %), при дальнейшем повышении дозы всасывание уменьшается (50-20 %). Связь с белками плазмы - 25 %. Заболевания ЖКТ (язвенная болезнь желудка и 12-перстной кишки, запоры или диарея, глистная инвазия, лямблиоз), употребление свежих фруктовых и овощных соков, щелочного питья уменьшают всасывание аскорбата в кишечнике. Распределение Концентрация аскорбиновой кислоты в плазме в норме составляет приблизительно 10-20 мкг/мл, запасы в организме - около 1,5 г при приеме ежедневных рекомендуемых доз и 2,5 г при приеме 200 мг/сут. ТСmах(период полувыведения) после приема внутрь - 4 ч. Метаболизм Метаболизируется преимущественно в печени в дезоксиаскорбиновую и далее в щавелевоуксусную и дикетогулоновую кислоты. Выведение Выводится почками, через кишечник, с потом, грудным молоком в виде неизмененного аскорбата и метаболитов. Рутозид Время максимальной концентрации в плазме крови после приема внутрь - 1-9 часов. Выводится преимущественно с желчью и в меньшей степени почками. 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