Повышенная чувствительность к препарату возраст до 3 лет.
Инструкция
Регистрационный номер
Р N000143/02 от 31.05.07
Торговое название препарата
Арбидол
Лекарственная форма
таблетки покрытые оболочкой
Состав
Таблетки, покрытые оболочкой, 50 мг
Активное вещество: арбидол в пересчете на безводное вещество - 0,05 г.
Вспомогательные вещества: крахмал картофельный, метилцеллюлоза МЦ-100, кремния диоксид коллоидный (аэросил), кальция стеарат - достаточное количество до получения таблетки массой 0,075 г (без оболочки). Оболочка: сахароза (сахар), повидон (поливинилпирролидон низкомолекулярный медицинский), титана диоксид, магния карбонат основной, тальк, кремния диоксид коллоидный (аэросил), мука, воск пчелиный (пасечный) - достаточное количество до получения таблетки, покрытой оболочкой, массой 0,15 г.
Таблетки, покрытые оболочкой, 100 мг
Активное вещество: арбидол в пересчете на безводный - 0,1 г.
Вспомогательные вещества: крахмал картофельный, метилцеллюлоза МЦ-100, аэросил (кремния диоксид коллоидный), кальция стеарат, кислота стеариновая - достаточное количество до получения таблетки массой 0,15 г (без оболочки). Оболочка: сахар, поливинилпирролидон низкомолекулярный медицинский (повидон), титана диоксид, магния карбонат основной, тальк молотый, аэросил (кремния диоксид коллоидный), воск пчелиный (пасечный) - достаточное количество до получения таблетки, покрытой оболочкой, массой 0,3 г.
Описание
Таблетки, покрытые оболочкой, 50 мг
Таблетки, покрытые оболочкой от белого до белого с кремоватым оттенком цвета, круглые, двояковыпуклые.
Таблетки, покрытые оболочкой, 100 мг
Таблетки, покрытые оболочкой, от белого до белого с кремоватым оттенком цвета, круглой формы, двояковыпуклые.
Фармакотерапевтическая группа
Противовирусное и иммуностимулирующее средство
Фармакологические свойства
Фармакодинамика:
Противовирусное средство оказывает иммуномодулирующее и противогриппозное действие специфически подавляет вирусы гриппа А и В тяжелого острого респираторного синдрома (ТОРС). Препятствует контакту и проникновению вирусов в клетку подавляя слияние липидной оболочки вируса с клеточными мембранами. Обладает интерферониндуцирующим действием стимулирует гуморальные и клеточные реакции иммунитета фагоцитарную функцию макрофагов повышает устойчивость организма к вирусным инфекциям. Снижает частоту развития осложнений связанных с вирусной инфекцией а также обострений хронических бактериальных заболеваний.
Терапевтическая эффективность при вирусных инфекциях проявляется в снижении выраженности общей интоксикации и клинических явлений сокращении продолжительности болезни.
Относится к малотоксичным препаратам (LD50 >4 г/кг). Не оказывает какого-либо отрицательного воздействия на организм человека при пероральном применении в рекомендуемых дозах.
Фармакокинетика:
Быстро абсорбируется и распределяется по органам и тканям. Максимальная концентрация в плазме крови при приеме в дозе 50 мг достигается через 12 ч в дозе 100 мг - через 15 ч. Метаболизируется в печени. Период полувыведения равен 17-21 ч.
Около 40% выводится в неизмененном виде в основном с желчью (38.9%) и в незначительном количестве почками (0.12%). В течение первых суток выводится 90% от введенной дозы.
Показания к применению
Профилактика и лечение у взрослых и детей:
- грипп А и В ОРВИ тяжелый острый респираторный синдром (ТОРС) (в том числе осложненные бронхитом пневмонией);
- вторичные иммунодефицитные состояния;
- комплексная терапия хронического бронхита пневмонии и рецидивирующей герпетической инфекции.
Профилактика послеоперационных инфекционных осложнений и нормализация иммунного статуса.
Комплексная терапия острых кишечных инфекций ротавирусной этиологии у детей старше 3 лет.
Противопоказания
Повышенная чувствительность к препарату возраст до 3 лет.
Способ применения и дозы
Внутрь до приема пищи. Разовая доза: детям от 3 до 6 лет -50 мг от 6 до 12 лет - 100 мг старше 12 лет и взрослым -200 мг (2 таблетки по 100 мг или 4 таблетки по 50 мг).
Для неспецифической профилактики.
При непосредственном контакте с больными гриппом и другими ОРВИ:
- детям от 3 до 6 лет - 50 мг от 6 до 12 лет - 100 мг старше 12 лет и взрослым - 200 мг один раз в день в течение 10-14 дней.
В период эпидемии гриппа и других ОРВИ для предупреждения обострений хронического бронхита рецидива герпетической инфекции:
- детям от 3 до 6 лет - 50 мг от 6 до 12 лет - 100 мг старше 12 лет и взрослым - 200 мг два раза в неделю в течение 3 недель.
Для профилактики ТОРС (при контакте с больным):
- взрослым и детям старше 12 лет назначают по 200 мг один раз в день в течение 12-14 дней.
Профилактика послеоперационных осложнений:
- детям от 3 до 6 лет - 50 мг от 6 до 12 лет - 100 мг старше 12 лет и взрослым - 200 мг за 2 суток до операции затем на 2 и 5 сутки после операции.
Для лечения.
Грипп другие ОРВИ без осложнений:
- детям от 3 до 6 лет - 50 мг от 6 до 12 лет - 100 мг старше 12 лет и взрослым - 200 мг 4 раза в сутки (каждые 6 часов) в течение 5 суток.
Грипп другие ОРВИ с развитием осложнений (бронхит пневмония и др.):
- детям от 3 до 6 лет - 50 мг от 6 до 12 лет - 100 мг старше 12 лет и взрослым- 200 мг 4 раза в сутки (каждые 6 часов) в течение 5 суток затем разовую дозу 1 раз в неделю в течение 4 недель.
Тяжелый острый респираторный синдром (ТОРС):
- взрослым и детям старше 12 лет - 200 мг 2 раза в день в течение 8-10 суток.
В комплексном лечении хронического бронхита герпетической инфекции:
- детям от 3 до 6 лет - 50 мг от 6 до 12 лет - 100 мг старше 12 лет и взрослым - 200 мг 4 раза в сутки (каждые 6 часов) в течение 5-7 суток затем разовую дозу 2 раза в неделю в течение 4 недель.
Комплексная терапия острых кишечных инфекций ротавирусной этиологии у детей старше 3 лет:
- от 3 до 6 лет - 50 мг от 6 до 12 лет - 100 мг старше 12 лет - 200 мг 4 раза в сутки (каждые 6 часов) в течение 5 суток.
Побочное действие
Редко - аллергические реакции.
Передозировка
Не отмечена.
Взаимодействие с другими лекарственными средствами
При назначении с другими лекарственными средствами отрицательных эффектов отмечено не было.
Влияние на способность управлять автомобилем и движущимися механизмами
Не проявляет центральной нейротропной активности и может применяться в медицинской практике в профилактических целях у практически здоровых лиц различных профессий в т.ч. требующих повышенного внимания и координации движений (водители транспорта операторы и т.д.).
Форма выпуска
Таблетки покрытые оболочкой 50 мг или 100 мг.
Условия хранения
Таблетки покрытые оболочкой 50 мг.
Список Б. В сухом защищенном от света месте при температуре от + 5 до + 30 °С.
Таблетки покрытые оболочкой 100 мг.
Список Б. В сухом защищенном от света месте при температуре не выше 25 °С.
Хранить в местах недоступных для детей.
Срок годности
2 года. Не использовать по истечении срока годности указанного на упаковке.
Условия отпуска
Без рецепта
Производитель
ОАО "ДАЛЬХИМФАРМ", 680001, Хабаровский край, г. Хабаровск, ул.Ташкентская, д.22, Россия
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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Оболочка: сахароза (сахар), повидон (поливинилпирролидон низкомолекулярный медицинский), титана диоксид, магния карбонат основной, тальк, кремния диоксид коллоидный (аэросил), мука, воск пчелиный (пасечный) - достаточное количество до получения таблетки, покрытой оболочкой, массой 0,15 г."}},{"type":"paragraph","data":{"text":"Таблетки, покрытые оболочкой, 100 мг"}},{"type":"paragraph","data":{"text":"Активное вещество: арбидол в пересчете на безводный - 0,1 г."}},{"type":"paragraph","data":{"text":"Вспомогательные вещества: крахмал картофельный, метилцеллюлоза МЦ-100, аэросил (кремния диоксид коллоидный), кальция стеарат, кислота стеариновая - достаточное количество до получения таблетки массой 0,15 г (без оболочки). Оболочка: сахар, поливинилпирролидон низкомолекулярный медицинский (повидон), титана диоксид, магния карбонат основной, тальк молотый, аэросил (кремния диоксид коллоидный), воск пчелиный (пасечный) - достаточное количество до получения таблетки, покрытой оболочкой, массой 0,3 г."}}]},{"id":5,"name":"Описание","slug":"common_description","body":[{"type":"paragraph","data":{"text":"Таблетки, покрытые оболочкой, 50 мг"}},{"type":"paragraph","data":{"text":"Таблетки, покрытые оболочкой от белого до белого с кремоватым оттенком цвета, круглые, двояковыпуклые."}},{"type":"paragraph","data":{"text":"Таблетки, покрытые оболочкой, 100 мг"}},{"type":"paragraph","data":{"text":"Таблетки, покрытые оболочкой, от белого до белого с кремоватым оттенком цвета, круглой формы, двояковыпуклые."}}]},{"id":6,"name":"Фармакотерапевтическая группа","slug":"","body":[{"type":"paragraph","data":{"text":"Противовирусное и иммуностимулирующее средство"}}]},{"id":7,"name":"Фармакологические свойства","slug":"pharmacologic_effects","body":[{"type":"header","data":{"text":"Фармакодинамика:","level":3}},{"type":"paragraph","data":{"text":"Противовирусное средство оказывает иммуномодулирующее и противогриппозное действие специфически подавляет вирусы гриппа А и В тяжелого острого респираторного синдрома (ТОРС). Препятствует контакту и проникновению вирусов в клетку подавляя слияние липидной оболочки вируса с клеточными мембранами. Обладает интерферониндуцирующим действием стимулирует гуморальные и клеточные реакции иммунитета фагоцитарную функцию макрофагов повышает устойчивость организма к вирусным инфекциям. Снижает частоту развития осложнений связанных с вирусной инфекцией а также обострений хронических бактериальных заболеваний."}},{"type":"paragraph","data":{"text":"Терапевтическая эффективность при вирусных инфекциях проявляется в снижении выраженности общей интоксикации и клинических явлений сокращении продолжительности болезни."}},{"type":"paragraph","data":{"text":"Относится к малотоксичным препаратам (LD50 >4 г/кг). Не оказывает какого-либо отрицательного воздействия на организм человека при пероральном применении в рекомендуемых дозах."}},{"type":"header","data":{"text":"Фармакокинетика:","level":3}},{"type":"paragraph","data":{"text":"Быстро абсорбируется и распределяется по органам и тканям. Максимальная концентрация в плазме крови при приеме в дозе 50 мг достигается через 12 ч в дозе 100 мг - через 15 ч. Метаболизируется в печени. Период полувыведения равен 17-21 ч."}},{"type":"paragraph","data":{"text":"Около 40% выводится в неизмененном виде в основном с желчью (38.9%) и в незначительном количестве почками (0.12%). В течение первых суток выводится 90% от введенной дозы."}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Профилактика и лечение у взрослых и детей:"}},{"type":"paragraph","data":{"text":"- грипп А и В ОРВИ тяжелый острый респираторный синдром (ТОРС) (в том числе осложненные бронхитом пневмонией);"}},{"type":"paragraph","data":{"text":"- вторичные иммунодефицитные состояния;"}},{"type":"paragraph","data":{"text":"- комплексная терапия хронического бронхита пневмонии и рецидивирующей герпетической инфекции."}},{"type":"paragraph","data":{"text":"Профилактика послеоперационных инфекционных осложнений и нормализация иммунного статуса."}},{"type":"paragraph","data":{"text":"Комплексная терапия острых кишечных инфекций ротавирусной этиологии у детей старше 3 лет."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"Повышенная чувствительность к препарату возраст до 3 лет."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Внутрь до приема пищи. 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В сухом защищенном от света месте при температуре от + 5 до + 30 °С."}},{"type":"paragraph","data":{"text":"Таблетки покрытые оболочкой 100 мг."}},{"type":"paragraph","data":{"text":"Список Б. В сухом защищенном от света месте при температуре не выше 25 °С."}},{"type":"paragraph","data":{"text":"Хранить в местах недоступных для детей."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"2 года. Не использовать по истечении срока годности указанного на упаковке."}}]},{"id":21,"name":"Условия отпуска","slug":"release_condition","body":[{"type":"paragraph","data":{"text":"Без рецепта"}}]},{"id":22,"name":"Производитель","slug":"","body":[{"type":"paragraph","data":{"text":"ОАО \"ДАЛЬХИМФАРМ\", 680001, Хабаровский край, г. 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