Комбинированное средство, действие которого
обусловлено входящими в его состав компонентами.
Кофеин
обладает стимулирующим влиянием на центральную нервную систему, что приводит к
уменьшению усталости и сонливости, к повышению умственной и физической работоспособности.
Парацетамол
оказывает жаропонижающее и анальгетическое действие: уменьшает болевой синдром,
наблюдающийся при простудных заболеваниях – боль в горле, головная боль,
мышечную и суставную боль, снижает высокую температуру.
Фенилэфрин
оказывает сосудосуживающее действие – уменьшает отек и гиперемию слизистых
оболочек верхних отделов дыхательных путей и придаточных пазух.
Фенирамин
оказывает противоаллергическое действие: устраняет зуд глаз, носа и горла,
отечность и гиперемию слизистых оболочек полости носа, носоглотки и придаточных
пазух носа, уменьшает экссудативные проявления.
Показания к применению
Симптоматическое лечение «простудных заболеваний»,
ОРВИ, в том числе, гриппа (лихорадочный синдром, болевой синдром, ринорея).
Противопоказания
- выраженный атеросклероз коронарных артерий;
- портальная гипертензия;
- повышенная чувствительность к симпатомиметическим
препаратам, парацетамолу и другим компонентам, входящим в состав препарата
РиниКолд ХотКап®;
- прием других препаратов, содержащих вещества,
входящие в состав препарата РиниКолд
ХотКап®;
- одновременный прием трициклических антидепрессантов,
ингибиторов МАО и прекращение их приема менее 2-х недель назад;
- одновременный прием бета-адреноблокаторов;
- беременность;
- период лактации;
- детский возраст (до 15 лет);
- алкоголизм.
С осторожностью
При наличии состояний, указанных в данном разделе,
перед применением препарата РиниКолд ХотКап® следует
проконсультироваться с врачом.
Применение при беременности и в период грудного вскармливания
В связи с отсутствием клинических данных безопасность
применения препарата РиниКолд ХотКап® при беременности и в период
грудного вскармливания не установлена, поэтому назначение препарата данной
категории пациентов противопоказано.
Способ применения и дозы
Для приема внутрь. Содержимое 1 саше (пакетика)
высыпать в стакан, залить горячей водой, перемешать до полного растворения и
выпить (по желанию можно добавить сахар или мед). Принимать препарат РиниКолд
ХотКап® необходимо с большим количеством жидкости, через 1-2 часа
после приема пищи. Взрослым и детям старше 15 лет: принимать по одному саше (пакетику)
3-4 раза в сутки с интервалами между приемами 4-6 часов. Максимальная суточная
доза – 4 саше (пакетика). Препарат РиниКолд ХотКап® не рекомендуется
применять более 5 дней как обезболивающее и более 3 дней как жаропонижающее без
предварительной консультации врача. Увеличение суточной дозы или
продолжительности лечения возможно только под наблюдением врача.
Побочное действие
Классификация частоты развития побочных эффектов,
рекомендованная Всемирной организацией здравоохранения (ВОЗ):
очень часто ≥1/10
часто от ≥1/100
до ˂1/10
нечасто от ≥1/1000
до ˂1/100
редко от ≥1/10000 до
˂1/1000
очень редко ˂1/10000
частота неизвестна по имеющимся
данным установить частоту возникновения не представлялось возможным
Нарушения
со стороны крови и лимфатической системы
часто: тошнота, рвота, боль в эпигастральной области,
диарея, сухость слизистой оболочки полости рта.
Нарушения
со стороны печени и желчевыводящих путей
редко: повышение активности печеночных трансаминаз,
гепатотоксическое действие.
Нарушения
со стороны кожи и подкожных тканей
очень редко:
- острый генерализованный экзантематозный пустулез
(ОГЭП), острое состояние с развитием гнойничковых высыпаний, характеризуется
лихорадкой и диффузной эритемой, сопровождающейся жжением и зудом (может
возникнуть отек лица, рук и слизистых);
- синдром Стивенса-Джонсона (ССД) (злокачественная
экссудативная эритема), тяжелая форма многоформной эритемы, при которой
возникают пузыри на слизистой оболочке полости рта, горла, глаз, половых
органов, других участках кожи и слизистых оболочек;
- токсический эпидермальный некролиз (ТЭН, синдром
Лайелла)(синдром является следствием обширного апоптоза кератиноцитов, что
приводит к отслойке обширных участков кожи в местах дермоэпидермального
соединения, пораженная кожа имеет вид ошпаренной кипятком).
Если Вы заметили один из описанных выше побочных
эффектов, следует прекратить приема препарата РиниКолд ХотКап® и
немедленно обратиться к врачу.
Передозировка
В случае передозировки препаратом РиниКолд ХотКап®
следует немедленно обратиться к врачу. Быстрое оказание медицинской помощи
является критически важным, даже если вы не наблюдаете каких-либо признаков или
симптомов.
Симптомы
(обусловлены наличием парацетамола)
Симптомы проявляются после приема парацетамола свыше 7,5-10
г.
Порог передозировки может быть снижен у пожилых
пациентов и детей, а также у пациентов, принимающих определенные лекарственные
средства (например, индукторы микросомальных ферментов печени), алкоголь или
страдающих истощением.
В течение первых 24 ч после приема – бледность кожных
покровов, тошнота, рвота; анорексия, абдоминальная боль; увеличение
протромбинового времени, нарушение метаболизма глюкозы, гипокалиемия и
метаболический ацидоз (в т.ч. лактоацидоз). Симптомы нарушения функции печени
могут появляться через 12-48 ч после передозировки: повышение активности
«печеночных» трансаминаз, гепатонекроз. В тяжелых случаях – печеночная
недостаточность с прогрессирующей энцефалопатией, кома. Редко печеночная
недостаточность развивается молниеносно и может осложняться почечной
недостаточностью (тубулярный некроз).
Лечение
В случае подозрения на передозировку препаратом
РиниКолд ХотКап® необходимо прекратить применение препарата и
немедленно обратиться за врачебной помощью.
Симптоматическое лечение: в первые 6 ч после
передозировки рекомендуется промывание желудка и прием энтеросорбентов
(активированный уголь и т.п.). Введение донаторов SH-групп и предшественников
синтеза глутатиона - метионина наиболее
эффективно в первые 8-9 ч после передозировки, ацетилцистеина - через 12 ч. Необходимость в проведении
дополнительных терапевтических мероприятий (дальнейшее введение метионина и
ацетилцистеина) определяется концентрацией парацетамола в крови, а также
временем, прошедшим после его приема.
Симптомы (обусловленные наличием кофеина)
Симптомы острой передозировки: абдоминальная боль;
рвота; чувство жара; покраснение лица; лихорадка; озноб; возбуждение;
бессонница; раздражительность; потеря аппетита; слабость; тремор; повышенный
мышечный тонус; состояние измененного сознания; бред; галлюцинации; повышение
артериального давления с последующей артериальной гипотензией; тахикардия;
тахипноэ; повышение диуреза; гипокалиемия; гипонатриемия; гипергликемия;
метаболический ацидоз; судороги; миоклония и рабдомиолиз; наджелудочковые и
желудочковые аритмии.
Угнетение ЦНС, гипертермия, антихолинергический
синдром (мидриаз, приливы крови к лицу, лихорадка сухость во рту, задержка
мочи, парез кишечника), тахикардия, артериальная гипотензия, артериальная гипертензия,
тошнота, рвота, возбуждение, дезориентация, галлюцинации, психоз, судороги,
аритмии. Редко у пациентов с ажитацией, судорогами или у пациентов в коме
развивается рабдомиолиз и почечная недостаточность.
При одновременном назначении с барбитуратами,дифенином,
карбамазепином, рифампицином и
другими индукторами микросомальных ферментов печени повышается риск развития
гепатотоксического действия парацетамола.
У большинства пациентов, длительно принимающих варфарин, редкое использование
парацетамола, как правило, мало или вообще не влияет на международное
нормализованное отношение (МНО). Однако при продолжительном регулярном
использовании парацетамол усиливает эффект непрямых антикоагулянтов (варфарина
и других производных кумарина), что увеличивает риск кровотечений.
Влияние
кофеина
Однократный прием большой дозы кофеина способствует
увеличению экскреции лития почками.
Резкое прекращение приема кофеина может привести к
увеличению концентрации лития в сыворотке крови.
Влияние
фенирамина
Фенирамин одновременно с ингибиторами моноаминооксидазы (МАО), фуразолидоном может привести
к гипертоническому кризу, возбуждению, гиперпирексии.
Влияние
фенилэфрина
Фенилэфрин при приеме с ингибиторами МАО может приводить к повышению артериального
давления.
Фенилэфрин снижает эффективность действия бета-адреноблокаторов и антигипертензивных препаратов.
Трициклические
антидепрессанты усиливают адреномиметическое действие
фенилэфрина, одновременное назначение галотана
повышает риск развития желудочковой аритмии.
Снижает гипотензивное действие гуанетидина, который, в свою очередь, усиливает
альфа-адреномиметическую активность фенилэфрина.
Особые указания
В период лечения препаратом РиниКолд ХотКап®
следует воздержаться от приема алкоголя, снотворных и анксиолитических
(транквилизаторы) лекарственных средств. Не принимать вместе с другими
лекарственными средствами, содержащими парацетамол.
Если симптомы заболевания ухудшаются, сохраняются или
появляются новые в течение 3-5 дней следует проконсультироваться с врачом.
Хранить в недоступном для детей месте. В случае
проглатывания препарата ребенком, следует немедленно обратиться за медицинской
помощью.
Препарат РиниКолд ХотКап®
может вызывать сонливость.
Условия хранения
Хранить в сухом месте при температуре не выше 25 °С,
в оригинальной упаковке (саше в пачке).
Срок годности
3 года.
Не использовать после истечения срока годности,
указанного на упаковке.
Для описания товара использована информация от партнера 36.6
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"}},{"type":"paragraph","data":{"text":"\u003ci\u003eКофеин\u003c/i\u003e\nобладает стимулирующим влиянием на центральную нервную систему, что приводит к\nуменьшению усталости и сонливости, к повышению умственной и физической работоспособности.\n"}},{"type":"paragraph","data":{"text":"\u003ci\u003eПарацетамол\u003c/i\u003e\nоказывает жаропонижающее и анальгетическое действие: уменьшает болевой синдром,\nнаблюдающийся при простудных заболеваниях – боль в горле, головная боль,\nмышечную и суставную боль, снижает высокую температуру. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eФенилэфрин\u003c/i\u003e\nоказывает сосудосуживающее действие – уменьшает отек и гиперемию слизистых\nоболочек верхних отделов дыхательных путей и придаточных пазух. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eФенирамин\u003c/i\u003e\nоказывает противоаллергическое действие: устраняет зуд глаз, носа и горла,\nотечность и гиперемию слизистых оболочек полости носа, носоглотки и придаточных\nпазух носа, уменьшает экссудативные проявления. "}}]},{"id":8,"name":"Показания к применению","slug":"indications","body":[{"type":"paragraph","data":{"text":"Симптоматическое лечение «простудных заболеваний»,\nОРВИ, в том числе, гриппа (лихорадочный синдром, болевой синдром, ринорея)."}}]},{"id":9,"name":"Противопоказания","slug":"contraindications","body":[{"type":"paragraph","data":{"text":"- выраженный атеросклероз коронарных артерий;"}},{"type":"paragraph","data":{"text":"- портальная гипертензия; "}},{"type":"paragraph","data":{"text":"- повышенная чувствительность к симпатомиметическим\nпрепаратам, парацетамолу и другим компонентам, входящим в состав препарата\nРиниКолд ХотКап®; "}},{"type":"paragraph","data":{"text":"- прием других препаратов, содержащих вещества,\nвходящие в состав препарата РиниКолд\nХотКап®;"}},{"type":"paragraph","data":{"text":"- одновременный прием трициклических антидепрессантов,\nингибиторов МАО и прекращение их приема менее 2-х недель назад;"}},{"type":"paragraph","data":{"text":"- одновременный прием бета-адреноблокаторов;"}},{"type":"paragraph","data":{"text":"- беременность;"}},{"type":"paragraph","data":{"text":"- период лактации;"}},{"type":"paragraph","data":{"text":"- детский возраст (до 15 лет);"}},{"type":"paragraph","data":{"text":"- алкоголизм."}}]},{"id":10,"name":"С осторожностью","slug":"cautions","body":[{"type":"paragraph","data":{"text":"При наличии состояний, указанных в данном разделе,\nперед применением препарата РиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e следует\nпроконсультироваться с врачом."}},{"type":"paragraph","data":{"text":"При заболеваниях сердца, артериальной гипертензии;\nбронхиальной астме, хронической обструктивной болезни легких, эмфиземе,\nхроническом бронхите; сахарном диабете, заболеваниях щитовидной железы,\nфеохромоцитоме, заболеваниях крови, дефиците глюкозо-6-фосфатдегидрогеназы,\nврожденных гипербилирубинемиях (синдромы Жильбера, Дубина-Джонсона и Ротора),\nодновременном приеме препаратов, способных отрицательно влиять на печень (например,\nиндукторов микросомальных ферментов печени), печеночной и/или почечной\nнедостаточности, остром гепатите, пилородуоденальной обструкции, стенозирующей\nязве желудка и/или двенадцатиперстной кишки, эпилепсии, закрытоугольной\nглаукоме, гиперплазии предстательной железы, а также пациентам, страдающим истощением\nи/или обезвоживанием."}}]},{"id":11,"name":"Применение при беременности и в период грудного вскармливания","slug":"pregnancy_warnings","body":[{"type":"paragraph","data":{"text":"В связи с отсутствием клинических данных безопасность\nприменения препарата РиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e при беременности и в период\nгрудного вскармливания не установлена, поэтому назначение препарата данной\nкатегории пациентов противопоказано."}}]},{"id":12,"name":"Способ применения и дозы","slug":"dosage","body":[{"type":"paragraph","data":{"text":"Для приема внутрь. Содержимое 1 саше (пакетика)\nвысыпать в стакан, залить горячей водой, перемешать до полного растворения и\nвыпить (по желанию можно добавить сахар или мед). Принимать препарат РиниКолд\nХотКап\u003csup\u003e®\u003c/sup\u003e необходимо с большим количеством жидкости, через 1-2 часа\nпосле приема пищи. Взрослым и детям старше 15 лет: принимать по одному саше (пакетику)\n3-4 раза в сутки с интервалами между приемами 4-6 часов. Максимальная суточная\nдоза – 4 саше (пакетика). Препарат РиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e не рекомендуется\nприменять более 5 дней как обезболивающее и более 3 дней как жаропонижающее без\nпредварительной консультации врача. Увеличение суточной дозы или\nпродолжительности лечения возможно только под наблюдением врача. "}}]},{"id":13,"name":"Побочное действие","slug":"side_effects","body":[{"type":"paragraph","data":{"text":"Классификация частоты развития побочных эффектов,\nрекомендованная Всемирной организацией здравоохранения (ВОЗ): "}},{"type":"paragraph","data":{"text":"очень часто ≥1/10"}},{"type":"paragraph","data":{"text":"часто от ≥1/100\n до ˂1/10"}},{"type":"paragraph","data":{"text":"нечасто от ≥1/1000\n до ˂1/100"}},{"type":"paragraph","data":{"text":"редко от ≥1/10000 до\n ˂1/1000"}},{"type":"paragraph","data":{"text":"очень редко ˂1/10000"}},{"type":"paragraph","data":{"text":"частота неизвестна по имеющимся\n данным установить частоту возникновения не представлялось возможным"}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны крови и лимфатической системы \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"очень редко: анемия, тромбоцитопения, агранулоцитоз,\nгемолитическая анемия, апластическая анемия, метгемоглобинемия, панцитопения,\nлейкопения."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны иммунной системы \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"частота неизвестна: кожная сыпь, зуд, крапивница,\nангионевротический отек, реакция гиперчувствительности, анафилактический шок.\u003ci\u003e\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны нервной системы\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"редко: головная боль, головокружение, сонливость,\nнарушение засыпания, повышенная возбудимость."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны органа зрения\u003c/i\u003e "}},{"type":"paragraph","data":{"text":"редко: мидриаз, парез аккомодации, повышение\nвнутриглазного давления."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны сердца \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"редко: тахикардия, ощущение сердцебиения."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны сосудов\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"редко: повышение артериального давления."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны дыхательной системы, органов грудной клетки и средостения \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"частота неизвестна: бронхоспазм, сухость слизистой\nоболочки носа."}},{"type":"paragraph","data":{"text":"\u003ci\u003eЖелудочно-кишечные\nнарушения\u003c/i\u003e "}},{"type":"paragraph","data":{"text":"часто: тошнота, рвота, боль в эпигастральной области,\nдиарея, сухость слизистой оболочки полости рта. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны печени и желчевыводящих путей \u003c/i\u003e"}},{"type":"paragraph","data":{"text":"редко: повышение активности печеночных трансаминаз,\nгепатотоксическое действие."}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны кожи и подкожных тканей\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"очень редко:"}},{"type":"paragraph","data":{"text":"- острый генерализованный экзантематозный пустулез\n(ОГЭП), острое состояние с развитием гнойничковых высыпаний, характеризуется\nлихорадкой и диффузной эритемой, сопровождающейся жжением и зудом (может\nвозникнуть отек лица, рук и слизистых); "}},{"type":"paragraph","data":{"text":"- синдром Стивенса-Джонсона (ССД) (злокачественная\nэкссудативная эритема), тяжелая форма многоформной эритемы, при которой\nвозникают пузыри на слизистой оболочке полости рта, горла, глаз, половых\nорганов, других участках кожи и слизистых оболочек;"}},{"type":"paragraph","data":{"text":"- токсический эпидермальный некролиз (ТЭН, синдром\nЛайелла)(синдром является следствием обширного апоптоза кератиноцитов, что\nприводит к отслойке обширных участков кожи в местах дермоэпидермального\nсоединения, пораженная кожа имеет вид ошпаренной кипятком). "}},{"type":"paragraph","data":{"text":"\u003ci\u003eНарушения\nсо стороны почек и мочевыводящих путей\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"частота неизвестна: нефротоксичность (почечная колика,\nглюкозурия, интерстициальный нефрит, папиллярный некроз), затруднение\nмочеиспускания."}},{"type":"paragraph","data":{"text":"Если Вы заметили один из описанных выше побочных\nэффектов, следует прекратить приема препарата РиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e и\nнемедленно обратиться к врачу."}}]},{"id":14,"name":"Передозировка","slug":"overdose","body":[{"type":"paragraph","data":{"text":"В случае передозировки препаратом РиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e\nследует немедленно обратиться к врачу. Быстрое оказание медицинской помощи\nявляется критически важным, даже если вы не наблюдаете каких-либо признаков или\nсимптомов. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы\n(обусловлены наличием парацетамола)\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Симптомы проявляются после приема парацетамола свыше 7,5-10\nг. "}},{"type":"paragraph","data":{"text":"Порог передозировки может быть снижен у пожилых\nпациентов и детей, а также у пациентов, принимающих определенные лекарственные\nсредства (например, индукторы микросомальных ферментов печени), алкоголь или\nстрадающих истощением. "}},{"type":"paragraph","data":{"text":"В течение первых 24 ч после приема – бледность кожных\nпокровов, тошнота, рвота; анорексия, абдоминальная боль; увеличение\nпротромбинового времени, нарушение метаболизма глюкозы, гипокалиемия и\nметаболический ацидоз (в т.ч. лактоацидоз). Симптомы нарушения функции печени\nмогут появляться через 12-48 ч после передозировки: повышение активности\n«печеночных» трансаминаз, гепатонекроз. В тяжелых случаях – печеночная\nнедостаточность с прогрессирующей энцефалопатией, кома. Редко печеночная\nнедостаточность развивается молниеносно и может осложняться почечной\nнедостаточностью (тубулярный некроз). "}},{"type":"paragraph","data":{"text":"\u003ci\u003eЛечение\n\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"В случае подозрения на передозировку препаратом\nРиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e необходимо прекратить применение препарата и\nнемедленно обратиться за врачебной помощью. "}},{"type":"paragraph","data":{"text":"Симптоматическое лечение: в первые 6 ч после\nпередозировки рекомендуется промывание желудка и прием энтеросорбентов\n(активированный уголь и т.п.). Введение донаторов SH-групп и предшественников\nсинтеза глутатиона - метионина наиболее\nэффективно в первые 8-9 ч после передозировки, ацетилцистеина - через 12 ч. Необходимость в проведении\nдополнительных терапевтических мероприятий (дальнейшее введение метионина и\nацетилцистеина) определяется концентрацией парацетамола в крови, а также\nвременем, прошедшим после его приема. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы (обусловленные наличием кофеина)\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Симптомы острой передозировки: абдоминальная боль;\nрвота; чувство жара; покраснение лица; лихорадка; озноб; возбуждение;\nбессонница; раздражительность; потеря аппетита; слабость; тремор; повышенный\nмышечный тонус; состояние измененного сознания; бред; галлюцинации; повышение\nартериального давления с последующей артериальной гипотензией; тахикардия;\nтахипноэ; повышение диуреза; гипокалиемия; гипонатриемия; гипергликемия;\nметаболический ацидоз; судороги; миоклония и рабдомиолиз; наджелудочковые и\nжелудочковые аритмии."}},{"type":"paragraph","data":{"text":"Симптомы хронической интоксикации кофеином\n«кофеинизм»: раздражительность; бессонница; беспокойство; эмоциональная\nлабильность; хроническая боль в животе."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы\n(обусловленные наличием хлорфенамина)\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Угнетение ЦНС, гипертермия, антихолинергический\nсиндром (мидриаз, приливы крови к лицу, лихорадка сухость во рту, задержка\nмочи, парез кишечника), тахикардия, артериальная гипотензия, артериальная гипертензия,\nтошнота, рвота, возбуждение, дезориентация, галлюцинации, психоз, судороги,\nаритмии. Редко у пациентов с ажитацией, судорогами или у пациентов в коме\nразвивается рабдомиолиз и почечная недостаточность."}},{"type":"paragraph","data":{"text":"\u003ci\u003eСимптомы\n(обусловленные наличием фенилэфрина)\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Тошнота; рвота; раздражительность; возбуждение;\nбессонница; психоз; судороги; ощущение сердцебиения; тахикардия; повышение\nартериального давления; рефлекторная брадикардия."}}]},{"id":15,"name":"Взаимодействие с другими лекарственными средствами","slug":"drugs_interaction","body":[{"type":"paragraph","data":{"text":"\u003ci\u003eВлияние\nпарацетамола\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Усиливает эффекты ингибиторов \u003ci\u003eмоноаминооксидазы (МАО)\u003c/i\u003e, \u003ci\u003eседативных\nпрепаратов, этанола.\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"При одновременном приеме с \u003ci\u003eдигоксином\u003c/i\u003e или другими \u003ci\u003eсердечными\nгликазидами\u003c/i\u003e может увеличиться риск развития аритмии и инфаркта миокарда."}},{"type":"paragraph","data":{"text":"\u003ci\u003eАнтидепрессанты,\nпротивопаркинсонические средства, антипсихотические средства, фенотиазиновые\nпроизводные\u003c/i\u003e – повышают риск развития задержки мочи,\nсухости во рту, запоров. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eГлюкокортикостероиды\u003c/i\u003e\nувеличивают риск развития глаукомы. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eИнгибиторы\nмикросомального окисления (циметидин)\u003c/i\u003e снижают риск\nгепатотоксического действия. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eМетоклопрамид\u003c/i\u003e\nи \u003ci\u003eдомперидон\u003c/i\u003e увеличивают, а \u003ci\u003eколестирамин\u003c/i\u003e снижает скорость всасывания\nпарацетамола. "}},{"type":"paragraph","data":{"text":"Парацетамол снижает эффективность \u003ci\u003eдиуретических\u003c/i\u003e препаратов. "}},{"type":"paragraph","data":{"text":"При одновременном назначении с \u003ci\u003eбарбитуратами,\u003c/i\u003e \u003ci\u003eдифенином\u003c/i\u003e,\n\u003ci\u003eкарбамазепином, рифампицином\u003c/i\u003e и\nдругими индукторами микросомальных ферментов печени повышается риск развития\nгепатотоксического действия парацетамола. "}},{"type":"paragraph","data":{"text":"У большинства пациентов, длительно принимающих \u003ci\u003eварфарин\u003c/i\u003e, редкое использование\nпарацетамола, как правило, мало или вообще не влияет на международное\nнормализованное отношение (МНО). Однако при продолжительном регулярном\nиспользовании парацетамол усиливает эффект непрямых антикоагулянтов (варфарина\nи других производных кумарина), что увеличивает риск кровотечений. "}},{"type":"paragraph","data":{"text":"\u003ci\u003eВлияние\nкофеина\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Однократный прием большой дозы кофеина способствует\nувеличению экскреции лития почками. "}},{"type":"paragraph","data":{"text":"Резкое прекращение приема кофеина может привести к\nувеличению концентрации лития в сыворотке крови."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВлияние\nфенирамина\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Фенирамин одновременно с \u003ci\u003eингибиторами моноаминооксидазы (МАО), фуразолидоном\u003c/i\u003e может привести\nк гипертоническому кризу, возбуждению, гиперпирексии."}},{"type":"paragraph","data":{"text":"\u003ci\u003eВлияние\nфенилэфрина\u003c/i\u003e"}},{"type":"paragraph","data":{"text":"Фенилэфрин при приеме \u003ci\u003eс ингибиторами МАО\u003c/i\u003e может приводить к повышению артериального\nдавления. "}},{"type":"paragraph","data":{"text":"Фенилэфрин снижает эффективность действия \u003ci\u003eбета-адреноблокаторов\u003c/i\u003e и \u003ci\u003eантигипертензивных\u003c/i\u003e препаратов."}},{"type":"paragraph","data":{"text":"\u003ci\u003eТрициклические\nантидепрессанты\u003c/i\u003e усиливают адреномиметическое действие\nфенилэфрина, одновременное назначение \u003ci\u003eгалотана\u003c/i\u003e\nповышает риск развития желудочковой аритмии."}},{"type":"paragraph","data":{"text":"Снижает гипотензивное действие \u003ci\u003eгуанетидина,\u003c/i\u003e который, в свою очередь, усиливает\nальфа-адреномиметическую активность фенилэфрина. "}}]},{"id":16,"name":"Особые указания","slug":"","body":[{"type":"paragraph","data":{"text":"В период лечения препаратом РиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e\nследует воздержаться от приема алкоголя, снотворных и анксиолитических\n(транквилизаторы) лекарственных средств. Не принимать вместе с другими\nлекарственными средствами, содержащими парацетамол."}},{"type":"paragraph","data":{"text":"Если симптомы заболевания ухудшаются, сохраняются или\nпоявляются новые в течение 3-5 дней следует проконсультироваться с врачом."}},{"type":"paragraph","data":{"text":"Хранить в недоступном для детей месте. В случае\nпроглатывания препарата ребенком, следует немедленно обратиться за медицинской\nпомощью."}},{"type":"paragraph","data":{"text":"Препарат РиниКолд ХотКап\u003csup\u003e®\u003c/sup\u003e\nможет вызывать сонливость."}}]},{"id":19,"name":"Условия хранения","slug":"storage","body":[{"type":"paragraph","data":{"text":"Хранить в сухом месте при температуре не выше 25 °С,\n в оригинальной упаковке (саше в пачке)."}}]},{"id":20,"name":"Срок годности","slug":"expiry_date","body":[{"type":"paragraph","data":{"text":"3 года."}},{"type":"paragraph","data":{"text":"Не использовать после истечения срока годности,\nуказанного на упаковке."}}]}],"source":null},"description_toggle":false,"short_description":"Комбинированное средство, действие которого обусловлено входящими в его состав компонентами.Кофеинобладает стимулирующим влиянием на центральную нервную систему, что приводит к уменьшению усталости и сонливости, к повышению умственной и физической работоспособности.Парацетамолоказывает жаропонижающее и анальгетическое действие: уменьшает болевой синдром, наблюдающийся при простудных заболеваниях – боль в горле, головная боль, мышечную и суставную боль, снижает высокую температуру.Фенилэфриноказывает сосудосуживающее действие – уменьшает отек и гиперемию слизистых оболочек верхних отделов дыхательных путей и придаточных пазух.Фенираминоказывает противоаллергическое действие: устраняет зуд глаз, носа и горла, отечность и гиперемию слизистых оболочек полости носа, носоглотки и придаточных пазух носа, уменьшает экссудативные проявления.","substance":[{"id":589,"title":"Фенилэфрин","title_latin":"Phenylephrinum","slug":"fenilefrin_589"},{"id":605,"title":"Парацетамол","title_latin":"Paracetamolum","slug":"paratsetamol_605"},{"id":1078,"title":"Кофеин","title_latin":"Coffeinum","slug":"kofein_1078"},{"id":1854,"title":"Фенирамин","title_latin":"Pheniraminum","slug":"feniramin_1854"}],"branding":null,"valid_for_quick_buy":true,"is_available_to_delivery":true,"comments":null,"image_alt":"Риниколд ХотКап - фото упаковки","image_share":{"isTouch":{"default":"https://vseapteki.ru/cropping/thumbnails/101/223678/share_default/"},"isFromTablet":{"default":"https://vseapteki.ru/cropping/thumbnails/101/223678/share_default/"}},"diseases":[],"other_packages":[{"id":204391,"title":"Риниколд ХотКап","subtitle":{"full":"Порошок, 5 шт, 5 г, для раствора для приема внутрь, апельсин","short":"Порошок, 5 шт, 5 г","package":"5 шт, 5 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