Амоксиклав Порошок, флакон, 5 шт, 500+100 мг+мг, для раствора для внутривенного введения

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Острый и хронический средний отит. Заглоточный абсцесс. Тонзиллит. Фарингит. Инфекции нижних отделов дыхательных путей, в т.ч.: Острый бронхит с бактериальной суперинфекцией. Хронический бронхит. Пневмония . Инфекции мочевыводящих путей. Гинекологические инфекции. Инфекции кожи и мягких тканей, включая укусы человека и животных. Инфекции костей и суставов. Инфекции брюшной полости, в т.ч. желчных путей ( холецистит , холангит ). Одонтогенные инфекции. Инфекции передаваемые половым путем (гонорея, шанкроид). Профилактика инфекций после хирургических вмешательств."}}]},{"id":4,"name":"Способ применения и дозы","slug":"dosage","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Препарат вводят в/в. Курс лечения составляет 5-14 дней. Продолжительность курса лечения определяется индивидуально. При уменьшении степени тяжести симптомов для продолжения терапии рекомендуется переход на пероральные формы препарата Амоксиклав. 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Применение при нарушении функции почек Для пациентов с почечной недостаточностью доза и/или интервал между введениями препарата должны быть скорректированы в зависимости от клиренса креатинина (см.таблицу). Клиренс креатинина Режим дозирования \u003e 0.5 мл/с (\u003e 30 мл/мин) коррекции дозы не требуется 0.166-0.5 мл/с (10-30 мл/мин) первая доза - 1.2 г (1000 мг + 200 мг), а затем по 600 мг (500 мг + 100 мг) в/в каждые12 ч \u003c 0.166 мл/с (\u003c 10 мл/мин) первая доза - 1.2 г (1000 мг + 200 мг), а затем по 600 мг (500 мг + 100 мг) в/в каждые 24 ч анурия интервал между введениями следует увеличить до 48 ч или больше Поскольку 85% Амоксиклава удаляется гемодиализом, введение препарата проводят по окончании процедуры гемодиализа. При перитонеальном диализе не требуется коррекции режима дозирования. Правила приготовления и введения растворов для в/в инъекций Следует растворить содержимое флакона 1.2 г (1000 мг+200 мг) в 20 мл воды для инъекций . В/в вводить медленно (в течение 3-4 мин.). Правила приготовления и введения растворов для в/в инфузий Для инфузионного введения Амоксиклава необходимо дальнейшее разведение: приготовленный раствор, содержащий 1.2 г (1000 мг+200 мг) препарата, должен быть разведен в 100 мл инфузионного раствора. Продолжительность инфузии 30-40 мин. При использовании перечисленных ниже инфузионных растворов в рекомендованных объемах в них сохраняются необходимые концентрации антибиотика. В качестве растворителя для в/в инфузий могут использоваться следующие инфузионные растворы. Инфузионный раствор Стабильность при 25°С Стабильность при 5°С Вода для инъекций 4 ч 8 ч Инфузионный раствор натрия хлорида (0.9%) 4 ч 8 ч Инфузионный раствор Рингера лактата 3 ч - Инфузионный раствор калия хлорида или натрия хлорида 3 ч - Амоксиклав менее стабилен в инфузионных растворах, содержащих декстрозу (глюкозу), декстран или бикарбонат. Амоксиклав следует вводить в течение 20 мин после приготовления растворов для в/в введения. Следует использовать только прозрачные растворы. Приготовленные растворы не замораживать."}}]},{"id":5,"name":"Побочное действие","slug":"side_effects","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы Потеря аппетита, тошнота, рвота , диарея. Редко - нарушения функции печени, повышение активности АЛТ и АСТ . в единичных случаях - холестатическая желтуха , гепатит, псевдомембранозный колит . Аллергические реакции Зуд, крапивница, эритематозные высыпания . редко - многоформная экссудативная эритема, ангионевротический отек, анафилактический шок. В единичных случаях - эксфолиативный дерматит, синдром Стивенса-Джонсона. Прочие Обратимое увеличение протромбинового времени (при совместном применении с антикоагулянтами). Редко - кандидоз и другие виды суперинфекции."}}]},{"id":6,"name":"Особые указания","slug":"cautions","displayInMenu":true,"body":[{"type":"paragraph","data":{"text":"Со стороны пищеварительной системы Потеря аппетита, тошнота, рвота , диарея. Редко - нарушения функции печени, повышение активности АЛТ и АСТ . в единичных случаях - холестатическая желтуха , гепатит, псевдомембранозный колит . Аллергические реакции Зуд, крапивница, эритематозные высыпания . редко - многоформная экссудативная эритема, ангионевротический отек, анафилактический шок. В единичных случаях - эксфолиативный дерматит, синдром Стивенса-Джонсона. Прочие Обратимое увеличение протромбинового времени (при совместном применении с антикоагулянтами). Редко - кандидоз и другие виды суперинфекции."}}]}],"source":{"title":"36.6","url":"https://366.ru"}},"description_toggle":false,"short_description":"Антибиотик широкого спектра действия . содержит полусинтетический пенициллин амоксициллин и ингибитор β .-лактамаз клавулановую кислоту. Клавулановая кислота образует стойкий инактивированный комплекс с β .-лактамазами и обеспечивает устойчивость амоксициллина к их воздействию. Клавулановая кислота, подобная по структуре бета-лактамным антибиотикам, обладает слабой собственной антибактериальной активностью. Таким образом, Амоксиклав . действует бактерицидно на широкий спектр грамположительных и грамотрицательных бактерий (в т.ч. на штаммы, которые приобрели устойчивость к бета-лактамным антибиотикам вследствие продукции β .-лактамаз). Амоксиклав . активен в отношении аэробных грамположительных бактерий: Streptococcus spp. (в т.ч. 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