Препарат растительного происхождения, применяемый при лечении доброкачественной гиперплазии предстательной железы. Оказывает антиандрогенное, противовоспалительное и противоотечное действие избирательно на ткани предстательной железы.; Механизм антиандрогенного действия обусловлен ингибированием активности 5-альфа-редуктазы (вследствие чего нарушается трансформация тестостерона в дигидротестостерон). Под влиянием этого фермента поступающий в предстательную железу тестостерон превращается в активную форму - дигидротестостерон. Простаплант препятствует образованию дигидротестостерон-рецептор-комплекса, проникновению его в ядро клетки и последующему индуцированию синтеза белка. В результате данного действия тормозится процесс пролиферативных изменений в тканях предстательной железы. Простаплант не влияет на уровни тестостерона, ФСГ и ЛГ в плазме крови у мужчин.; Противовоспалительное и противоотечное действие препарата обусловлено ингибированием ферментов - циклооксигеназы и 5-липооксигеназы.; Простаплант уменьшает капиллярную проницаемость и сосудистый стаз, уменьшает отек и воспаление предстательной железы, устраняя таким образом компрессию на шейку мочевого пузыря и уретру, улучшая динамику мочевыводящих путей.; Применение препарата способствует уменьшению специфических симптомов доброкачественной гиперплазии предстательной железы (дизурия, поллакурия, никтурия, снижение объема и силы мочеиспускания, неполное опорожнение мочевого пузыря, болезненные ощущения и чувство напряжения в промежности на I и II стадии заболевания).; Простаплант не снижает потенцию, не оказывает влияния на уровень простат-специфического антигена (ПСА) в плазме крови.
Показания к применению
Нарушения мочеиспускания при доброкачественной гиперплазии (аденоме) предстательной железы I и II стадии.
Противопоказания
Повышенная чувствительность к препарату.
Применение при беременности и в период грудного вскармливания
Данные не предоставлены.
Способ применения и дозы
Внутрь, не разжевывая, запивая небольшим количеством жидкости.; По 1 капс. 1 раз в сутки; продолжительность курса лечения — не менее 3 мес.; Оптимальную схему лечения и повторные курсы в каждом отдельном случае назначает врач, основываясь на результатах диагностического обследования.;
Побочное действие
В отдельных случаях — тошнота, изжога, гастралгия (при приеме натощак); возможны аллергические реакции.
Передозировка
До настоящего времени о случаях передозировки препарата Простаплант не сообщалось.
Особые указания
С осторожностью следует назначать препарат пациентам с заболеваниями ЖКТ в анамнезе.; Перед применением препарата следует убедиться в том, что заболевание носит доброкачественный характер.
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Информация предоставляется в справочных целях. Не занимайтесь самолечением. При первых признаках заболевания обратитесь к врачу.
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